My mother was diagnosed with breast cancer 3 years ago, with stage1 (2.2cm). Her nodes were clean. After complete breast surgery she was given chemo. Now at the same time, there was a lump of 5 mm on lower left lung which has now grown to 1.1cm. Doctor has taken that out now. Now the histopathology of the tissue is concluded at metastatic breast cancer. My question if the old tumor was removed at a stage 1, how come it had spread to lung? Metastatic takes place in stage3 /4. Is it possible the biopsy is wrong? What should we do here?
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Hi. You are right that stage 1 ca breast usually does not show metastasis. However there may be a micrometastasis which can be missed on x ray ultrasound ct and even on pet scan. So it's unfortunate that your mother developed lung mets. May be the primary tumour was poor differentiating with lymphovascular invasion. These kind of tumors may be small in size but may metastazise early and often resistant to chemo.
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Respected lybrate-userhi there are always remote possibilities of micrometastasis in any stage of cancer. So histopatho is wrong we can not stamp directly yes for our satisfaction we can definately get review of slides by another expert pathologist for double assurance thanks regards.
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