Hello doctor, my sister is 41 years old and has 2 sons. She was diagnosed with seronegative rheumatoid arthritis 4 years back. Initially she took allopathic medicine then she switched to a combination of naturopathy with homeopathy. But still symptoms were not improved. Now she is taking ashwagandha, triphala & guduchi and she is feeling better but in cold weather, she experience some pain. She is doing walking, meditation, mantra chanting and pranayama. But she has anxiety and the symptoms of depression like hopeless, sad, less energy, slow speaking etc. Sometime she says she should not live. She is not coming to consult doctor. I request, please suggest me what kind of treatment like ayurveda, allopathy or homeopathy will be effective to treat her depression with less side effects.