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I have been taking glitaris m7. 5/500 one tablet after dinner for sugar control for more than 10 years. This has been banned again in india. My endocrinologist is of the opinion that I should not stop pioglitazone (the reason, it facilitates utilization of insulin in body cells). Secondly, I am taking it in low intensity (7.5 mg). My questions are the following. 1. Does it have harmful effect? 2. Is the side effect related to quantity of pioglitazone one is taking? Meaning, is to safe to take it in low amount as in my case? 3. Though this tablet is banned, glitaris 7.5 mg is available in market (exclusive pioglitazone). Can I take this with one additional tablet glycomet 500 (metformin)? If yes, 4. If combination tablet glitaris m7. 5/500 is unsafe (because it is banned) then how the same in separate form, glitaris 7.5 + glycomet 500, can be safe?
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Mr. lybrate-user, thanks for the query. As told by your endocrinologist pioglitazone does help insulin action by reducing resistance to its action. The combination has been banned because it is considered as irrational to have certain "fixed dose" combinations. Because it is difficult to make dosage adjustment in asuch a combination. However, using those separately is absolutely fine. Plus if you have been getting good glucose control with those drugs, then please do use separately. At the dose you are taking pioglitazone is quite safe. Thanks.
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