Pioglitazone is a drug used to control high blood sugar levels in patients with type 2 diabetes. It is an anti diabetic drug. It makes the blood cells more sensitive to the action of insulin thus lowering the blood sugar levels in the body. It is used in combination with a proper diet and exercise program to maximize its effects. It also helps in preventing kidney damage, nerve problems and sexual problems. Controlling blood sugar level also helps reduce the risk of a heart attack or stroke.
Pioglitazone is a drug used to control high blood sugar level in patients with type 2 diabetes. It is an anti diabetic drug. It makes the blood cells more sensitive to the action of insulin thus lowering the blood sugar level. It is used alongside a proper diet and exercise program to maximize its effects. It also helps in preventing kidney damage, nerve problems and sexual problems. Controlling blood sugar level also helps reduce the risk of heart attack or stroke.
Pioglitazone is a prescribed drug and should always be taken under the guidance of a medical expert. It is available in three doses: 15mg, 30 mg and 45mg orally consumed tablets. The course duration for this medication is normally3 to 6 months after which the doctor examines its effects on the patient.
There are a few conditions under which you shouldn’t take Pioglitazone: if you are allergic to any ingredients of this medicine, if you have suffered from a heart attack in the past or if you have any liver disease. It is also important to mention to your doctor if you are currently using any prescribed drugs or dietary supplements. Pioglitazone might also cause changes in the menstrual cycle and increase the risk of becoming pregnant. Hence, it is advisable to use reliable birth control while using this medication. During pregnancy, use this drug only when it’s extremely necessary. Pioglitazone might also cause certain side effects.
Some common side effects of this medication are: cold, headache or sore throat. These side effects last for a few days before going away on their own. However sometimes severe side effects occur in which case one should immediately consult the doctor. These side effects are allergic reactions, blurred vision, symptoms of liver problems (like dark urine, stomach trouble or vomiting), or symptoms of low blood sugar. These side effects appear rarely, but if they do, you should immediately consult the doctor.
Pioglitazone should be stored at a temperature between 15 to 25 degrees C. It should be kept moisture free and away from direct sunlight. Keep it out of the reach of children or pets.type diabetes
How long is the duration of effect?The effect of this medicine lasts for an average of 24 hours.
What is the onset of action?The effect of this medicine can be observed within an hour of oral administration. However, it takes 2-4 hours for the medicine to reach its peak effect.
Are there any pregnancy warnings?This medicine is not recommended for use in pregnant women. There is a possibility of an adverse effect on the fetus and there is a lack of conclusive evidence from clinical studies. It is advisable to consult your doctor.
Is it habit forming?No habit forming tendencies were reported
Are there any breast-feeding warnings?This medicine is suspected of passing into breast milk and having a harmful effect on the baby. Alternative therapy should be considered in such cases after consulting the doctor.
Are there any missed dose instructions?The missed dose can be taken as soon as you remember. If it is time for the next dosage then the missed dose can be skipped.
Are there any overdose instructions?It is recommended to discontinue the medication and contact your doctor immediately if an overdose is suspected. Symptoms like dizziness, confusion, increased heartbeat, tremor and sweating after taking the medication should be reported immediately.
Below is the list of medicines, which contains Pioglitazone as ingredient
This medication works by activating peroxisome proliferator activator receptor causing an increase in the production of components that breaks down lipids and glucose in the body. It also increases insulin response without affecting its secretion.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
EthanolConsumption of alcohol in large quantities is not recommended when you are taking Pioglitazone for controlling blood sugar levels. It is recommended to reduce the alcohol intake so that the adverse effects can be avoided. Symptoms of both reduced or elevated blood sugar levels should be reported to the doctor immediately.
Interaction with Lab Test
Elevated ALTYou should consult the doctor about the usage of Pioglitazone if a liver test is to be taken in immediate future. This is necessary as the likelihood of getting a false result is very high in such cases.
Interaction with Medicine
GatifloxacinPioglitazone is not recommended for use along with Gatifloxacin. You should report the use of either of the medicines to the doctor. Symptoms of high blood sugar, as well as low blood sugar, should be reported immediately. You should not stop the usage of any medicine without talking to the doctor.
MiconazolePioglitazone should not be used with the oral form of Miconazole. Report the usage of either of the medication to the doctor. Suitable dose adjustment and safety monitoring are required in these cases. Symptoms like headache, dizziness, tremor, sweating after taking these medicines should be reported immediately.
FluconazolePioglitazone should not be used with Fluconazole. Report the usage of either of the medication to the doctor. Suitable dose adjustment and safety monitoring are required in these cases. Symptoms like headache, dizziness, tremor, sweating after taking these medicines should be reported immediately.
RifampinPioglitazone should not be used with Rifampin. Report the usage of either of the medication to the doctor. Suitable dose adjustment and safety monitoring are required in these cases. Symptoms like increased thirst, hunger, and urination after taking these medicines should be reported immediately.
ColesevelamReport the usage of either of these medications to the doctor. Pioglitazone and Colesevelam should be taken with suitable time gap to avoid the interaction from happening. Normally, there should be a gap of 4 hours between the administration of these two medicines.
DiclofenacPioglitazone should not be co-administered with Diclofenac or other NSAIDs. Appropriate dosage adjustment and more frequent monitoring of blood sugar levels are necessary in such cases. Do not stop the usage of any drug without consulting your doctor.
Interaction with Disease
Heart DiseasesPioglitazone should be administered with extreme caution if you suffer from any disease of heart and blood vessels.
Kidney DiseasePioglitazone should be administered with extreme caution in you suffer from any disease of the kidneys. You should consult your doctor to make suitable adjustment in dosage quantity and/or time-interval between two dosages.
HypoglycemiaPioglitazone should be administered with caution in if you are prone to having episodes of low blood sugar. This population includes diabetics who are also malnourished or those receiving Beta-blocker drugs such as Metoprolol and Propranolol.
Hemolytic Anemia/G6Pd DeficiencyPioglitazone is not recommended for use in people suffering from Hemolytic Anemia. Reporting this condition to the doctor is a must. In such cases, alternate medication not belonging to Sulfonylureas should be considered.
Interaction with Food
FoodInformation not available.
Pioglitazone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 26 May 2022].Available from:https://druginfo.nlm.nih.gov/drugportal/name/pioglitazone
Pioglitazone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 26 May 2022].Available from:https://go.drugbank.com/drugs/DB01132
PIOGLITAZONE Capsule,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 26 May 2022].Available from:https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=PIOGLITAZONE
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