Acute intermittent porphyria (AIP) is a rare autosomal dominant metabolic disorder affecting the production of heme, the oxygen-binding prosthetic group of hemoglobin. It is characterized by a deficiency of the enzyme porphobilinogen deaminase.The most common type of porphyria is porphyria cutanea tarda (PCT), which affects the skin. PCT is also the most treatable. No known cure exists for any type of porphyria.
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