Prescribed to control some types of seizures that may result due to epilepsy and treat bipolar disorder, Lamotrigine is meant for oral consumption. The drug is available in the form of regular tablets that have to be swallowed, tablets that can be chewed or those that dissolve in the mouth. Extended release tablets are also available.
Before starting the medication you should be aware of some of the common side effects of Lamotrigine. They are-
- feeling sleepy, or insomnia
- headache, which may be accompanied with blurred or double vision
- back pain
- runny nose, sore throat and fever
- skin rashes
Some serious side effects of Lamotrigine include rashes that can result in sores or blisters, multi-organ hypersensitivity which can lead to fever, acute pain in the muscles and yellowing of the skin. Behavioral changes may also result, which may include suicidal thoughts, panic attacks, anger, aggressiveness and restlessness.
Patients should inform their doctor about the medication that they are already taking for other health problems before starting Lamotrigine. This is because certain drugs interfere with the effectiveness of Lamotrigine. for instance oral contraceptives reduces the level of Lamotrigine, thus affecting the action of the drug. HIV drugs as well as tuberculosis medicines have the same effect on Lamotrigine.
The dosage of the drug prescribed may vary from individual to individual depending on the age, health condition, severity of the health problem, and reaction to the initial dose. Initially the doctor may begin with a 25 mg dose and increase it gradually. A dosage up to 300 mg can be taken according to the reaction to the medicine. In case of liver of kidney problems the doctor may prescribe the drug after conducting a thorough medical check-up.
- hyperactivity and tiredness are some of the symptoms of bipolar disorder.
How long is the duration of effect?The effect of this medicine lasts for an average duration of 2 to 3 days.
What is the onset of action?The peak effect of this medicine can be observed in 1 to 1.5 hours for an immediate release tablet and 4 to 11 hours for an extended release tablet.
Are there any pregnancy warnings?This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.
Is it habit forming?No habit forming tendency has been reported.
Are there any breast-feeding warnings?This medicine is not recommended for breastfeeding women unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.
Missed Dose instructionsIf you miss a dose of Lamotrigine, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose instructionsSeek emergency medical treatment or contact the doctor in case of an overdose.
Below is the list of medicines, which contains Lamotrigine as ingredient
This medication works by reducing the excitation of the brain cells by inhibiting the sodium channels and stabilizes the neuronal membranes thus inhibits the repetitive firing of brain cells.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
AlcoholConsumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
Interaction with Lab Test
LabInformation not available.
Interaction with Medicine
Ethinyl EstradiolThe desired effect of Lamotrigine may not be observed if taken with oral contraceptives. The dose of Lamotrigine should be adjusted to achieve better seizure control. Any symptoms of worsening of seizures should be reported to the doctor.
RifampinThe desired effect of Lamotrigine may not be observed if taken with rifampin. The dose of Lamotrigine should be adjusted to achieve better seizure control. Any symptoms of worsening of seizures should be reported to the doctor.
Valporic AcidConcomitant use of these medications may increase the risk of serious skin reactions. Any symptoms of skin rash, itching should be reported to the doctor. An alternative medication should be considered based on the clinical condition.
Interaction with Disease
DepressionLamotrigine should be given with caution in the patients with depression and suicidal thoughts. Frequent monitoring of depression symptoms is necessary. Dose adjustments are to be made based on the outcomes in the patient.
Aseptic MeningitisLamotrigine may increase the risk of aseptic meningitis. Any symptoms of neck rigidity, headache and fever should be reported to the doctor immediately. Discontinue the treatment until the cause is identified.
Interaction with Food
FoodInformation not available.
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Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.