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Etanercept

Prescription vs.OTC: Prescription by Doctor required

Etanercept is a biological medicine which is used for treating inflammatory conditions such as rheumatoid arthritis, plaque psoriasis, ankylosing spondylitis, psoriatic arthritis, polyarticular juvenile idiopathic arthritis. Etanercept blocks the TNF (tumor necrosis factor alpha) that causes inflammation. It is usually injected in the body and shows results in 2-10 weeks.

Etanercept is US FDA approved, but has some side effects as well. Some common side effects include pain, headache, itching, bruising, sore throat, redness, swelling and dizziness. It can also aggravate or lead to serious conditions like fungal infections, sepsis, or tuberculosis. Some cases of cancers have also been reported in children. Patents with serious infections are advised to use it with caution and doctor's prescription.

The drug is especially dangerous for people with chickenpox. It can also lead to nervous system problems such as sclerosis and seizures. It can also weaken the heart and lead to heart problems. It should be avoided by people who are allergic to latex, are pregnant or are planning to do so, have been in close proximity to a person with chicken pox.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Rheumatologist before using this medicine.

In addition to its intended effect, Etanercept may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Upper respiratory tract infection

Rash

Injection site reaction.

Is It safe with alcohol?

Interaction with alcohol is unknown. Please consult your doctor.

Are there any pregnancy warnings?

Etacept 25mg injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.

Are there any breast-feeding warnings?

Unknown. Human and animal studies are not available. Please consult your doctor.

Is it safe to drive while on this medicine?

There is no data available. Please consult doctor before consuming the drug.

Does this affect kidney function?

There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

Does this affect liver function?

There is no data available. Please consult doctor before consuming the drug.

Are there any missed dose instructions?

If you miss a dose of Etanercept, please consult your doctor.
Below is the list of medicines, which contains Etanercept as ingredient
Intas Pharmaceuticals Ltd
Intas Pharmaceuticals Ltd
Etanercept is a Tumour Necrosis Factor (TNF) inhibitor which is used in treating autoimmune diseases. There are two forms of TNF receptors – p55 and p75. Etanercept works as p75 TNF receptor which can bind two TNF molecules and hence remove it from circulation.
What are you using Etanercept for?
Ankylosing Spondylitis
Psoriasis
Rheumatoid Arthritis
Other
How much was the improvement?
Average
Excellent
Poor
How long did it take before seeing improvement?
More than 2 days
Within a day
How frequently did you take this medicine?
Not taking on daily level
Once a day
How did you take this medicine?
With or without food
What were the side effects of this medicine?
Other
Injection site reaction
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Hi sir, I am 32 years old male. I have rheumatoid arthritis. Any medicine for it. and any particular diet.

FRAS, MD - Ayurveda, Bachelor of Ayurveda, Medicine & Surgery (BAMS)
Alternative Medicine Specialist, Ernakulam
Ra can be well managed with ayurveda treatment and pancha karma, consult a ayurveda specialist in your city or come to kerala for authentic ayurveda treatment.
2 people found this helpful

rheumatoid arthritis is a very big problem for my wife. she will be suffering from almost 10 years what is the remedies for this and she gone for all sorts of treatments its not working her body please help me out from this point of view thank you sir.

Dip. SICOT (Belgium), MNAMS, DNB (Orthopedics), MBBS
Orthopedist, Delhi
Hi thanks for your query and welcome to lybrate. I am Dr. Akshay from fortis hospital, new delhi. As you must be knowing by now, rheumatoid arthritis is a chronic inflammatory joint disease which has a genetic predisposition. Since this is a genetically linked disease hence as of now there is no permanent cure for it, but there are new injectable medications like etanercept etc which are available which help in disease control. You need a very active lifestyle with intensive regular physical therapy, take adequate calcium and vitamin d supplementation you also need to be in touch of a rheumatologist as it needs a long term supervised care. Do not hesitate to contact me if you need any further assistance.
8 people found this helpful

I am 62 years male, have psoriasis only on both hands mainly on sides n undersides of fingers for past 1 year. Small cracks form n heal in a day or two. Hv bn applying skin creams n sorifix cream. Need help.

PDDM, MHA, MBBS
General Physician, Nashik
I am 62 years male, have psoriasis only on both hands mainly on sides n undersides of fingers for past 1 year. Small ...
Psoriasis is an inflammatory skin disease characterised by well defined erythematous scaly plaques with silvery white or candle wax type of scaling. Chronic plaque psoriasis is the most common type. It can affect sites like scalp, arms, and legs, (specifically elbows and knees), palms and soles etc. Other types of psoriasis are: Erythrodermic psoriasis, Pustular psoriasis (generalised and localised), Nail psoriasis and Scalp psoriasis. There are various precipitating factors for psoriasis: Infections (sore throat, dental infections etc), drugs (b-blockers used for hypertension), pregnancy, winters (psoriasis becomes worse in winters), stress, alcohol intake and cigarette smoking, topical irritants like coal tar, salicylic acid and withdrawal of oral/ topical steroids etc. The disease has a chronic course and there topical creams/ointments/gels/lotions etc as well as oral and injectable medicines which can treat psoriasis but there is no permanent cure for psoriasis. For limited disease involving < 20% of BSA, Topical treatment alone suffices: -Moisturisers specially those which contain hygroscopic (attract water from the atmosphere and lock it into the skin) and keratoloytic agents like Ammonium lactate (Amylac cream), Urea, Lactic acid etc are especially useful in dry scaly conditions like psoriasis. -For the patches you could use a steroid+salicylic acid ointment, twice daily (clobetasol+3% OR 6% salicylic acid in an ointment base e.g propysalic NF Ointment) over and above the moisturiser for 4 weeks. -Other treatment modalities which can be used for localized plaque psoriasis are: Vitamin D analogues like calcipotriol, calcipotriene alone or in combination with steroid. For extensive psoriasis (involving more than 20% of BSA) oral as well as topical treatment is combined together: -Once weekly oral methotrexate is another option in case of plaque psoriasis but it should always be taken under the supervision of a dermatologist since it can rarely cause serious side effects like bone marrow suppression. -Oral cyclosporine is given for extensive psoriasis involving more than 20% of the body surface area. It is rapidly effective but it requires monitoring of kidney functions and BP. Other commonly used oral treatment modalities are: -Oral Psoralens e.g 8-methoxypsoralen and UV A phototherapy (PUVA) -Narrow-Band phototharapy (NB-UVB) -Biologics response modifiers (Etanercept, Infliximab, Adalimumab etc) To summarize, in limited psoriasis only topical agents are used, whereas if the disease involves >20% body surface area, it is better to combine both topical and oral therapies. I would suggest that you see a dermatologist and have a fair discussion regarding the most appropriate treatment modalities for you.
2 people found this helpful

I'm suffering from joint pains like knee elbow arms fingers soldiers ankle n back. I'm female aged about 38 years my weight is 50 kgs. please give me good advice.

M.B.S.(HOMEO), MD - Homeopathy
Homeopath, Visakhapatnam
I'm suffering from joint pains like knee elbow arms fingers soldiers ankle n back. I'm female aged about 38 years my ...
Arthritis is a general term for numerous conditions that affect bone joints; scientists do not know exactly what cause arthritis. Some think the disease is genetic-something that is inherited from your parents. Other think arthritis is caused by infection, obesity, bone damage, or another disease. Regardless of the cause or type of arthritis, people with arthritis experience chronic pain and swelling in their joints. Symptoms associated with arthritis Mainly stiffness, redness, swelling, limitation of movements, may also associated with fever, weight loss, carditis in specific medical conditions of arthritis. Treatment of arthritis Drug treatment – includes Anti-Inflammatory agents, ranging from mild and familiar oral medication, such as aspirin, to powerful new medications, such as etanercept and infliximab. Immunosuppressive medicines (drugs that inhibit the immune system) may be prescribed in rheumatoid arthritis, especially when the activity of disease is moderate or severe. Some important remedies are given below for the homeopathic treatment of arthritis: Bryonia Alba. – Pain with inflammation which, is aggravated by movement and relieved by moderate pressure and rest. Ledum pal. – Excellent remedy for gout and rheumatism which is of ascending nature, better by cold application. Rhus Tox. – Pain aggravated by first movement, damp weather and better by continuous motion.
1 person found this helpful

Hi, I am a 59-year old suffering from psoriatic arthritis for the last 6 years. There has been severe itching too lately. I take an anti-histamine like Piriton nightly to control itchiness and help me to sleep as well, as recently I also suffer from insomnia. Is it okay for me to take Atarax 25 mg as well nightly? Or should I take 2 tablets Piriton instead?

Erasmus Mundus Master in Adapted Physical Activity, MPT, BPTh/BPT
Physiotherapist, Chennai
Hi, I am a 59-year old suffering from psoriatic arthritis for the last 6 years. There has been severe itching too lat...
No cure exists for psoriatic arthritis, so treatment focuses on controlling inflammation in your affected joints to prevent joint pain and disability. Medications Drugs used to treat psoriatic arthritis include: NSAIDs. Nonsteroidal anti-inflammatory drugs (NSAIDs) can relieve pain and reduce inflammation. Over-the-counter NSAIDs include ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve). Stronger NSAIDs are available by prescription. Side effects may include stomach irritation, heart problems, and liver and kidney damage. Disease-modifying antirheumatic drugs (DMARDs). These drugs can slow the progression of psoriatic arthritis and save the joints and other tissues from permanent damage. Common DMARDs include methotrexate (Trexall), leflunomide (Arava), and sulfasalazine (Azulfidine). Side effects vary but may include liver damage, bone marrow suppression and severe lung infections. Immunosuppressants. These medications act to tame your immune system, which is out of control in psoriatic arthritis. Examples include azathioprine (Imuran, Azasan) and cyclosporine (Gengraf, Neoral, Sandimmune). These medications can increase your susceptibility to infection. TNF-alpha inhibitors. Tumor necrosis factor-alpha (TNF-alpha) is an inflammatory substance produced by your body. TNF-alpha inhibitors can help reduce pain, morning stiffness, and tender or swollen joints. Examples include etanercept (Enbrel), infliximab (Remicade), adalimumab (Humira), golimumab (Simponi) and certolizumab (Cimzia). Potential side effects include nausea, diarrhea, hair loss and an increased risk of serious infections. Newer medications. Some newly developed medications for plaque psoriasis can also reduce the signs and symptoms of psoriatic arthritis. Examples include apremilast (Otezla), ustekinumab (Stelara) and secukinumab (Cosentyx). Surgical and other procedures Steroid injections. This type of medication reduces inflammation quickly and is sometimes injected into an affected joint. Joint replacement surgery. Joints that have been severely damaged by psoriatic arthritis can be replaced with artificial prostheses made of metal and plastic.

Popular Health Tips

Juvenile Rheumatoid Arthritis - Know More About It!

MBBS, MD - Internal Medicine, MRCEM(UK), MEM, Diploma in Rheumatology, PGCC - Rheumatology, MACEP, FCCS
Internal Medicine Specialist, Kolkata
Juvenile Rheumatoid Arthritis - Know More About It!

Juvenile rheumatoid arthritis also known as juvenile idiopathic arthritis is a commonly occurring arthritis in children under the age of 15. Some common problems that are faced by patients with this disease include stiffness, joint pain, and swelling. While the symptoms might persist for a few months for some patients, for others it might continue for the rest of their lives. Patients might face serious complications such as inflammation of the eye, problems related to growth etc. The treatment of this condition focuses on preventing the bones from getting damaged, pain control and improving the function of the body.

What are some of the common symptoms of juvenile arthritis?

  1. Pain: A child suffering from juvenile rheumatoid arthritis might face extreme pain in the joints. They might limp after a nap or night sleep due to pain or stiff joints.

  2. Swelling: Larger joints such as the knee might swell frequently. The swelling might occur in smaller joints too.

  3. Stiffness: In addition to limping the child might appear rough and clumsy after waking from night sleep or a nap.

Other conditions could include rashes, swollen lymph nodes, frequent fever, headache, etc.

What are the causes of Juvenile Rheumatoid Arthritis?

Juvenile Rheumatoid Arthritis occurs when the immune system of the body attacks its own tissues and cells. It is still unclear as to why it happens, although, researchers believe that the environment and heredity have a role to play. Certain genetic mutations might make a child more vulnerable and susceptible to microbes that can trigger this condition.

What are the complications involved?

There could be several complications that might arise due to this condition. It is, therefore, wise to keep a close watch on the child. Seeking immediate medical attention can go a long way in mitigating the risk of these complications.

  • Problems related to the eye: Juvenile Rheumatoid arthritis can damage the eye by causing an inflammation known as uveitis. If this condition is not treated, it might result in other conditions such as glaucoma, cataracts, blindness etc.

  • Growth problems: Juvenile rheumatoid arthritis could result in growth problems. To treat this, a child would require a dose of corticosteroid.

How to diagnose juvenile arthritis?

It is not very easy to diagnose juvenile arthritis. Doctors often prescribe blood tests to get an idea of erythrocyte sedimentation rate, rheumatoid factor, C-reactive protein, anti-nuclear antibody, cyclic citrullinated peptide etc. A doctor might also prescribe imaging tests such as X-rays, MRI etc to detect congenital defects, fractures, tumors etc.

What are the treatment options available?

The overall treatment goal is to control symptoms, prevent joint damage, and maintain function. Oral steroids such as prednisone, deflazocort may be used in certain situations, but only for as short a time and at the lowest dose possible. Some of the medications that are prescribed for this condition include NSAID such as ibuprofen and naproxen, DMARD such as methotrexate and leflunomide, TNF blockers such as adalimumab and etanercept, immune suppressants such as rituximab. In addition to this, doctors would also prescribe exercises and therapies.

3865 people found this helpful

Options Other Than Knee Replacement

MBBS, M. S., SR (AIIMS),FIJRS (SOUTH KOREA)
Orthopedist, Delhi
Options Other Than Knee Replacement

There is no cure for arthritis but there are a number of treatments that may help relieve the pain and disability it can cause.

  • As with other arthritic conditions, initial treatment of arthritis of the knee is nonsurgical. Your doctor may recommend a range of treatment options.
  • Lifestyle modifications. Some changes in your daily life can protect your knee joint and slow the progress of arthritis.
  • Minimize activities that aggravate the condition, such as climbing stairs.
  • Switching from high impact activities (like jogging or tennis) to lower impact activities (like swimming or cycling) will put less stress on your knee.
  • Losing weight can reduce stress on the knee joint, resulting in less pain and increased function.
  • Physical therapy. Specific exercises can help increase range of motion and flexibility, as well as help strengthen the muscles in your leg. Your doctor or a physical therapist can help develop an individualized exercise program that meets your needs and lifestyle.
  • Assistive devices. Using devices such as a cane, wearing shock-absorbing shoes or inserts, or wearing a brace or knee sleeve can be helpful. A brace assists with stability and function, and may be especially helpful if the arthritis is centered on one side of the knee. There are two types of braces that are often used for knee arthritis: an" unloader" brace shifts weight away from the affected portion of the knee, while a" support" brace helps support the entire knee load.
  • Other remedies. Applying heat or ice, using pain-relieving ointments or creams, or wearing elastic bandages to provide support to the knee may provide some relief from pain.
  • Medications. Several types of drugs are useful in treating arthritis of the knee. Because people respond differently to medications, your doctor will work closely with you to determine the medications and dosages that are safe and effective for you.
  • Over-the-counter, non-narcotic pain relievers and anti-inflammatory medications are usually the first choice of therapy for arthritis of the knee. Acetaminophen is a simple, over-the-counter pain reliever that can be effective in reducing arthritis pain.
  • Like all medications, over-the-counter pain relievers can cause side effects and interact with other medications you are taking. Be sure to discuss potential side effects with your doctor.
  • Another type of pain reliever is a nonsteroidal anti-inflammatory drug, or nsaid (pronounced" en-said"). Nsaids, such as ibuprofen and naproxen, are available both over-the-counter and by prescription. A cox-2 inhibitor is a special type of nsaid that may cause fewer gastrointestinal side effects. Common brand names of cox-2 inhibitors include celebrex (celecoxib) and mobic (meloxicam, which is a partial cox-2 inhibitor). A cox-2 inhibitor reduces pain and inflammation so that you can function better. If you are taking a cox-2 inhibitor, you should not use a traditional nsaid (prescription or over-the-counter). Be sure to tell your doctor if you have had a heart attack, stroke, angina, blood clot, hypertension, or if you are sensitive to aspirin, sulfa drugs or other nsaids.
  • Corticosteroids (also known as cortisone) are powerful anti-inflammatory agents that can be injected into the joint these injections provide pain relief and reduce inflammation; however, the effects do not last indefinitely. Your doctor may recommend limiting the number of injections to three or four per year, per joint, due to possible side effects.
  • In some cases, pain and swelling may" flare" immediately after the injection, and the potential exists for long-term joint damage or infection. With frequent repeated injections, or injections over an extended period of time, joint damage can actually increase rather than decrease.
  • Disease-modifying anti-rheumatic drugs (dmards) are used to slow the progression of rheumatoid arthritis. Drugs like methotrexate, sulfasalazine, and hydroxychloroquine are commonly prescribed.
  • In addition, biologic dmards like etanercept (embril) and adalimumab (humira) may reduce the body's overactive immune response. Because there are many different drugs today for rheumatoid arthritis, a rheumatology specialist is often required to effectively manage medications.
  • Viscosupplementation involves injecting substances into the joint to improve the quality of the joint fluid.
  •  Glucosamine and chondroitin sulfate, substances found naturally in joint cartilage, can be taken as dietary supplements. Although patient reports indicate that these supplements may relieve pain, there is no evidence to support the use of glucosamine and chondroitin sulfate to decrease or reverse the progression of arthritis.
5 people found this helpful

Spondyloarthritis

MD
General Physician, Secunderabad
Spondyloarthritis

Spondyloarthritis (also known as spondyloarthropathy) is the term which describes the connective tissue diseases. It is the group of inflammatory diseases, including arthritis of the peripheral joints and spine (sacroiliitis or spondylitis); including the area where ligaments and tendons attach to bones (enthesitis or enthesopathy). These diseases cause pain or stiffness in the leg or arm joints, spine, ligaments and tendons become inflamed. Skin rashes, eye, and intestinal problems may also be able to occur.

Epidemiology

  • Spondyloarthritis is a pathology that specifically strikes young people. The symptoms most frequently start before the age of 45. It affects more males than females.
  • Predisposition to spondyloarthritis, especially spa, is determined largely by genetic factors.
  • The incidence rate is higher in populations with a higher prevalence of hla-b27.
  • Psoriatic skin lesions and colitis due to inflammatory bowel disease (ibd) have been considered as both basic, subtype-defining entities with their own genetic background (distinct from hla-b27 genotype), and as manifestations of spondyloarthritis.
  • There is a strong need to diagnose patients with spa in an earlier stage; currently, there is a delay of 5–10 years between onset of the first symptoms and diagnosis.

Types

There are five types of spondyloarthritis

Ankylosing spondylitis or bechterew disease: it is the type of arthritis that affects the spine. Symptoms include pain and stiffness in the lower back and in the neck. Spine bones fuse together and it will become rigid spine and it leads to stoope over posture.

Psoriatic arthritis: psoriatic arthritis is the form of arthritis that affects the people who have psoriasis. Most people diagnosed with psoriasis and later diagnosed with psoriatic arthritis. It may affect any part of the body such as fingertips and spine. The main symptoms are joint pain, stiffness, and swelling.

Psoriatic arthritis

Reactive arthritis: it occurs due to the infection by certain bacteria. Often the bacteria’s from genitals (chlamydia trachomatis) or bowel (campylobacter, salmonella, shigella, and yersinia). It usually targets your knees and joints of ankles or feet.

Reactive arthritis

Undifferentiated arthritis: undifferentiated inflammatory arthritis does not conform to any of the recognized inflammatory arthritis types. It may include monoarthritis of a single joint; oligoarthritis, which is usually when four or fewer joints are involved; or polyarthritis, which usually involves many small joints.

Risk factors

Risk factors may be higher due to following reasons:

  • Family member having the gene which causes spondyloarthritis
  • Positive results for the hla-b27 gene
  • Recurring bacterial infection in your gut
  • Have other inflammatory conditions such as psoriasis or inflammatory bowel disease

Causes

  • The main cause is not known, but researchers pointed out that the hereditary genetics playing an important role in this disease. Since this disease occurs often in family members of patients who have spondyloarthritis.
  • Many genes cause it. Up to 30 genes have been found. But the major gene that causes spondyloarthritis is hla-b27.
  • Bacterial infections can also cause reactive spondyloarthritis known to be triggered by a bacteria chlamydia or food borne infections.

Symptoms and complications of spondyloarthritis

The first and major symptoms of all types of spondyloarthritis are severe low back pain, swelling of arms, stiffness, and fatigue. The different types of spondyloarthritis can be manifested by the following signs and symptoms.

  • Alternative or unilateral buttock pain
  • Arthritis in small joints
  • Arthritis in large joints such as knee joint, ankle joint and elbow joint (peripheral arthritis)
  • Numbness and tingling sensation in arms and legs
  • Spinal fusion may occur in ankylosing spondylitis
  • Inflammation at the interfaces between bone and tendon or ligament of limbs (enthesitis)
  • Inflammation of intestine, urinary tract and aortic heart valves. These can lead to spinal joints inflammation.
  • Inflammation of joints in pelvis and spine (sacroiliitis)
  • Enteropathic arthritis shows symptoms such as diarrhea and abdominal pain
  • Digestive problems
  • Skin disease like psoriasis
  • Osteoporosis
  • Redness of eye (iritis)
  • Swollen fingers and
  • Pain in the heels cause difficult to walk, stand even for small duration

Diagnosis and testing

First a doctor may ask for patient’s medical history, physical exam and may suspects for symptoms of spondyloarthritis. To confirm doctor may perform the following diagnosis and tests.

  • X-rays: x-ray images shows the change of the sacroiliac joints in the pelvis and fusion of spine. If these changes not observed, but symptoms shows spondyloarthritis doctor will suggest mri scan. Mri shows these changes more promptly than the x-ray.
  • Mri scans: it can show a very clear image of enthesitis and also the changes of sacroiliac joints.
  • Ct scans: ct also used for the imaging of bone joints.
  • Hla-b27: most patients with spondyloarthritis have hla-b27 gene, but some people don’t have this gene. So it is necessary to go for a hla-b27 test if the symptoms suspects spondyloarthritis.
  • Complete blood count (cbc): cbc can be useful to find the inflammation.
  • Musculoskeletal ultrasound scanning: ultrasound imaging uses sound waves to produce the images of inflammatory conditions of muscles, ligaments, and tendons.
  • Dual-energy x-ray absorptiometry (dexa) scans: used for measuring the bone mineral density usually the bones of the lower spine and hips. Bone loss is measured through this technique.

Treatment of spondyloarthritis.

  • There is no way to cure this disease condition, but there are treatments to counterparts the symptoms.
  • Nonsteroidal anti-inflammatory drugs: certain nsaid’s like naproxen, ibuprofen, meloxicam, or indomethacin are prescribed by doctors to relief from the pain due to symptoms.
  • Corticosteroid medication: inflammation around the tendons and in the joints can be overcome by taking some corticosteroid drugs. This helps to reduce the swelling in the joints.
  • Antibiotics: antibiotics can be used in the case of reactive spondyloarthritis in which bacteria cause the major problems.
  • Disease-modifying antirheumatic drugs (dmard’s): sulfasalazine (azulfidine) and methotrexate are the best dmard’s to be used for the joint damages in limbs affected by arthritis.
  • Tumor necrosis alpha (tnf-alpha) blockers: fda approved tnab are adalimumab (humira), adalimumab-atto (amjevita), a biosimilar to humira, certolizumab pegol (cimzia), etanercept (enbrel), etanercept-szzs (ereizi), a biosimilar to enbrel, golimumab (simponi), infliximab (remicade), infliximab-dyyb (inflectra), a biosimilar to remicade, and secukinimab (cosentyx). These are biosimilars used to treat arthritis in spine joints.
  • Surgery: patients with over inflammation of pelvis joints needs hip replacement. In the case of heavy damage in the cartilage of joints needs surgery to repair. In some rare cases, spinal surgery also needed.

Prevention and control measures

  • Prevention from spondyloarthritis needed some lifestyle changes as follows.
  • Quit smoking: smoking speeds up the spinal fusion in addition to other bad health effects.
  • Follow good posture: practicing a proper sitting and posture makes your spine to escape from growing into slumped-over position and strain.
  • Daily physical exercise: frequent home exercise and physiotherapy is essential to reduce the stiffening of spine and other joint problems. It also helps to have your heart healthy.
  • Good diet: follow the diets that are rich in calcium. Dairy products are preferred foe calcium rich foods.
Psoriatic arthritis
4 people found this helpful

Rheumatoid Arthritis!

MD - Acupuncture, Diploma In Accupuncture, Advanced Diploma In Accupuncture
Acupuncturist, Delhi
Rheumatoid Arthritis!

Rheumatoid Arthritis 

Treatment of Rheumatoid arthritis
Homeopathic Treatment of Rheumatoid arthritis
Acupuncture & Acupressure Treatment of Rheumatoid arthritis
Psychotherapy Treatment of Rheumatoid arthritis
Conventional / Allopathic Treatment of Rheumatoid arthritis
Surgical Treatment of Rheumatoid arthritis
Dietary & Herbal Treatment of Rheumatoid arthritis
Other Treatment of Rheumatoid arthritis
What is Rheumatoid arthritis
Symptoms of Rheumatoid arthritis
Causes of Rheumatoid arthritis
Risk factors of Rheumatoid arthritis
Complications of Rheumatoid arthritis
Lab Investigations and Diagnosis of Rheumatoid arthritis
Precautions & Prevention of Rheumatoid arthritis
Treatment of Rheumatoid arthritis

Homeopathic Treatment of Rheumatoid arthritis

Homeopathy is extremely successful in treating rheumatoid arthritis. Homeopathic treatment gives relief in arthritis with inflammation, pain, stiffness and lameness. It is useful in preventing and treating deformities associated with the disease. Some of the homeopathic remedies that can be used for treatment of rheumatoid arthritis are:

Arnica
Bryonia
Calcarea
Causticum
Chinin s
Dulcamara
Kali carb
Pulsatilla
 

Acupuncture & Acupressure Treatment of Rheumatoid arthritis

The acupuncture and acupressure stimulate dilation of the blood vessels, potentially reducing swelling and pain. Acupuncture and Acupressure helps in nourishing the tendons and joints. It also has a strong effect on promoting the smooth flow of chi throughout the body. Obstruction to the smooth flow of chi causes pain and discomfort. Acupuncture gives lasting relief in rheumatoid arthritis.

Psychotherapy and Hypnotherapy Treatment of Rheumatoid arthritis

Psychotherapy and hypnotherapy can help in stress relief. They can help in better coping and early relief.

Conventional / Allopathic Treatment of Rheumatoid arthritis

Allopathic Treatment of Rheumatoid arthritis involves the following medications:

NSAIDs – ibuprofen and naproxen
Steroids – prednisone
DMARDs – leflunomide and hydroxychloroquine
Immunosuppressants – cyclosporine and cyclophosphamide
TNF-alpha inhibitors – etanercept and infliximab
 

Surgical Treatment of Rheumatoid arthritis

Surgical Treatment of Rheumatoid arthritis involves the following surgeries:

Total joint replacement
Tendon repair
Joint fusion
 

Dietary & Herbal Treatment of Rheumatoid arthritis

Eat foods rich in omega-3 fatty acid such as soybeans, walnuts and avocados
Avoid saturated fats
Avoid fried and grilled food
Avoid tea and coffee
 

Other Treatment of Rheumatoid arthritis

Heat compresses relax your muscles and stimulate blood flow
Applying cold also decreases muscle spasms.
 

What is Rheumatoid arthritis

Rheumatoid arthritis (RA) is a form of arthritis that causes pain, swelling, stiffness and loss of function in your joints. Hands, feet and wrists are commonly affected, but it can also damage other parts of the body.

Symptoms of Rheumatoid arthritis

Swollen joints
Pain in the joints
Fatigue
Fever
Weight loss
Morning stiffness
 

Causes of Rheumatoid arthritis

The exact cause of rheumatoid arthritis is unknown.

Risk factors of Rheumatoid arthritis

More common in women
Between the ages of 40 and 60
Cigarette smoking
Family history
 

Complications of Rheumatoid arthritis

Carpal tunnel syndrome
Heart problems
Lung disease
Deformities
Osteoporosis
 

Diagnosis of Rheumatoid arthritis

Diagnosis of Rheumatoid arthritis involves the following tests:

Physical exam
Blood tests
X-rays
 

Precautions & Prevention of Rheumatoid arthritis

You can gain control of rheumatoid arthritis and improve your chances by taking the following steps:

Get the treatment early
Avoid exercising tender, injured or severely inflamed joints
Rest when you need to
Use a cane in the hand opposite a painful hip or knee

Ankylosing Spondylitis!

MD - Acupuncture, Diploma In Accupuncture, Advanced Diploma In Accupuncture
Acupuncturist, Delhi
Ankylosing Spondylitis!

Ankylosing Spondylitis Overview:
Arthritis can affect the quality of life of the affected in multifold ways. Ankylosing spondylitis is a type of arthritis can affects the spine. Pain and stiffness that runs from the neck to the lower back are the symptoms of this disease. This is an inflammation that can cause chronic pain and even lead to disability. Deformity too can be caused as the pain in the spine can lead to the formation of a new bone. It is not the only the neck and lowers back region that experiences the terrible pain, but even the other parts of the body are affected by this condition.

When affected by this condition, inflammation occurs between the vertebrae. This can also affect the joints in a few people. This can limit the movement of the affected. This disease often begins in early adolescence. When the spine becomes rigid, one can start seeing the changes. The changes can start at any point of time when the disease ranges from mild to severe. Over time, the affected also get a stooped posture. The disease is more common in Native Americans, and milder in women.

 

Ankylosing Spondylitis Symptoms:
1.    Pain and arduousness:
It is usual to experience the numbness, pain and stiffness in the back, buttocks and in the hips. When the symptoms exist for more than 3 months, the condition is moving from mild to severe. This usually begins in the lowest part of the spine, called the sacrum.

2.    Bony fusion: the Abnormal joining of bones is called bony fusion, and ankylosing spondylitis can lead to this overgrowth of bones. This can occur in major joints like the neck, hips, or back. The affected starts losing efficiency in performing the daily chores. In severe cases, the affected will also find it very tough to take a deep breath.

3.    Pain in tendons and sinews: The ligaments and sinews attached to the bones can be affected by ankylosing spondylitis. The inflammation of tendons called tendonitis is often on the cards. The pain and stiffness beneath the area of the heel can be experienced. This specific condition is called Achilles tendon. The back of the ankle is also affected, and the patient often finds it difficult to walk.

4.    Other symptoms: This disease is systematic, and this is why the pain and discomfort are not related to certain areas only. Affected people can experience symptoms like fatigue, fever, eye inflation, problems in heart and lungs, and loss of appetite.

5.    Weight loss, early morning stiffness, and anaemia are some of the symptoms experienced.

6.    Inflammation in the bowels and heart valve inflammation too are experienced as this is an inflammatory disease

Causes of Ankylosing Spondylitis:
The exact cause for this disease is not yet clear. Doctors point fingers at the genetic susceptibility. But, it is also be understood that not all who are affected by this disease carry the gene HLA B27. The major point is that people who carry this gene, have the higher risk of a hit by this type of arthritis. The risk percentage is higher by 10 to 20%.

What is risk factors Ankylosing Spondylitis:
If one carries the HLA B2 protein, the chances of getting affected are higher. The same is the case when one or more family members are affected by this disease. The symptoms are often seen beginning at the age of 20 to 40 years. This is also common in men, and women are rarely affected by this condition.

How to diagnosed Ankylosing Spondylitis?
1.    The diagnosis for ankylosing spondylitis is done through various ways. One of the major ways the doctor might identify the disease in the presence of the symptoms. Hence, it is important for the patients to ensure all the pain and discomfort experienced in different parts of the body should be intimated to the doctor.

2.    A physical examination is carried out by the healthcare professionals to identify the inflammation. The doctor also might ask to move and stretch the limbs, to identify the affected areas. Restricted movements often unveil the disease.

3.    X-rays are taken to notice the inflammation in the neck and the pelvic region. This screening offers a clear picture of the inflammation in various joints.

4.    The chest breathing examination is carried out to check if the condition has an impact on the lungs and causes difficulty in breathing

5.    The blood tests and other lab tests are also suggested by the doctor to check for anaemia, and other possible disorders that are associated with this condition.

6.    Urinalysis is also recommended by the doctors. This is because the inflation can also affect the function of the kidney. This can be checked at the right moment with the urine sample test done at the lab.

Treatment of Ankylosing Spondylitis:
It has to be understood that ankylosing spondylitis has no cure. It can be treated to ensure that the discomfort and pain are reduced. The movement functions can be improved to ensure that the patient can do the daily chores with ease. The stiffness and pain are the major problems with the condition, and these can be eradicated to a great extent by this treatment. The goal of the treatment is also to prevent further damage and help retain a good posture. Proper treatment, methods help the affected to lead a fairly normal life, without having to depend on others. A team of doctors are involved in the treatment plan. Doctor, occupational therapist, ophthalmologist, who treats eye disease,  gastroenterologist, who treats bowel disease,  physiatrist, who specializes in physical medicine and rehabilitation,  and a physical therapist, who provides stretching and exercise programs are present in the team.

1.   Physical and occupational therapy: it is important to opt for these therapies at the initial stages to ensure that deformity is not formed. These therapies are given by trained professionals, who suggest a range of exercises specific to your needs and help in improving the functions,  and also keep off from forming deformities due to reduced movements. For instance, a stooped posture can be corrected or prevented with the occupational and physical therapy.

 

2.   Exercises: Exercises improve the daily functioning of the individuals, and help in proper posture maintenance. Apart from the exercise schedule the occupational therapist and the physical therapists suggest, the doctors can also suggest a list of exercises that can help in promoting deep breathing. When done regularly they can immensely help a lot. An exercise that is considered to be the best is swimming. For those, who cannot swim, the other options are yoga poses that help in improving the breathing pattern without any trouble.

 

3.   Medications: Drugs are the important part of the treatment plan for ankylosing spondylitis, for they alone offer the much demanded instant relief from pain and stiffness caused by this disease. These drugs also ensure that the patients can do the exercises to improve the condition without facing much discomfort. Else, carrying out the daily chores too can be strenuous for the patients. The anti-inflammatory drugs that do not involve the use of steroids are often prescribed for this disease. A few examples are aspirin and ibuprofen. Disease-modifying antirheumatic drugs (DMARDs) like methotrexate (Rheumatrex)  can be used when the condition is not mild, but severe. This is because the NSAIDs are not enough to control the inflammation. Other FDA approved drugs like certolizumab pegol (Cimzia), golimumab (Simponi Aria, Simponi), infliximab (Remicade), and infliximab-day (Inflectra), a biosimilar to Remicade, and secukinumab (Cosentyx), etanercept (Enbrel), etanercept-szzs (Erelzi), a biosimilar to Enbrel, and adalimumab (Humira), adalimumab-atto (Amjevita), a biosimilar to Humira,too are prescribed currently. The chronic back pain can also be dealt with a few anti-depressants.

 

4.   Surgery:  When the inflammation has affected the hips and waist joints very much, a joint replacement surgery is done. This has to be decided by the doctor, and various factors can be responsible for the doctor going against the same.

Apart from the treatment options, there are certain do’s and doughnuts that are instructed by the doctors to live with this condition.

 

1.    Smoking exacerbates the condition. In many diseases, smoking can see to be aggravating the complications, and it is the same in the case of ankylosing spondylitis too. Smoking can impact inflammation. So, the patients are restricted from smoking.

2.    Sleeping on the firm bed is a must. Too soft mattresses can aggravate the pain. Sleeping on the back is what the patients are supposed to do. It is also advised not to use large and soft pillows. Very thin pillows or cotton bed sheets can be folded under the head. This is because the neck fusion can be triggered by using large pillows.

3.    Propping legs on pillows is another thing the patients are restricted to do. This is because, in the bent position, hip and knee fusion can result.

4.    The tables, chairs and other work surfaces should be in such a degree that the stooping posture should not be encouraged. 

5.    Using armchairs is a good option, for they offer ample of support to the arms and shoulders.

6.    Jumping, falling, and dancing can cause severe damage in the severe cases of the disease. The patient should take immense care in such cases.

 

Prevention of Ankylosing Spondylitis:
It is not easy to prevent ankylosing spondylitis. In fact, it is near to impossible. Majorly because the cause is unknown, the prevention is also yet to be known.  However, if there are 1 or more family members diagnosed with this condition, then it is a good option to find the risk chances. Yearly health checkups can help in avoiding this condition. Leading a sedentary life too can add to the chances of getting affected by this condition. So, involving physical activities, and doing regular exercises can prevent this disease to a certain extent. Exercises can help in improving the flexibility, and in people who are very active, the symptoms are identified soon, making it easy to get treated even at the initial stages. It is also essential to stay off from smoking and tobacco. Even when not diagnosed with any form of arthritis, these substances can increase the risk factor and aggravate the condition. Eating a healthy diet is also recommended. This inflammatory disease can also lead to inflammation of the heart. So, when adding the junk and fatty foods, the heart can lose its efficiency sooner.  A healthy diet can cut out the risk by half. 

 

Complications of Ankylosing Spondylitis:
1.    Fusion of the spine can lead to a curvature, which is called kyphosis. This can lead to a stooped posture when ankylosing spondylitis is left over time untreated.

2.    The pain is often felt in the groin area when the hi; tp and shoulder joints are affected. This is called referred pain, which can be felt in the thighs too. This can have an impact on the occupational front of the patient too.

3.    In most severe and rare cases, the heart’s electric functioning is also affected. This is because of the inflammation of the heart valves. A pacemaker must be brought in to ensure the proper functioning of the heart in such cases.

4.    In 10% of the cases, the joints near the jaws are affected. This can lead to the problem not able to open the jaw fully to eat.

5.    In the case of a few patients, the eye inflation can affect the quality of life, in case proper treatment is not given on time.

 

Myths:
Myth #1:  
 Ankylosing spondylitis affects only runs in families: only the risk factors high, and doesn’t mean it cannot occur to someone who has none in the family affected by this disease.

Myth #2:    Exercises can prevent the occurrence: While exercising can keep symptoms at bay for long, and help in easy diagnosing at early stages, it does not guarantee to stay far from this disease.

Myth #3:    Women are not affected: the risk factor for women is low. Men are affected 2 to 3 times higher but do not mean, women are spared by this disease.

It is not easy to lead a normal life with ankylosing spondylitis. It takes immense determination to fight this progressive disease. Sticking to medication and active lifestyle can only help to live with this disease.

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