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Overview

Etacept 25Mg Injection

Manufacturer: Cipla Ltd
Medicine composition: Etanercept
Prescription vs.OTC: Prescription by Doctor required

Etacept 25Mg Injection is a biological medicine which is used for treating inflammatory conditions such as rheumatoid arthritis, plaque psoriasis, ankylosing spondylitis, psoriatic arthritis, polyarticular juvenile idiopathic arthritis. Etacept 25Mg Injection blocks the TNF (tumor necrosis factor alpha) that causes inflammation. It is usually injected in the body and shows results in 2-10 weeks.

Etacept 25Mg Injection is US FDA approved, but has some side effects as well. Some common side effects include pain, headache, itching, bruising, sore throat, redness, swelling and dizziness. It can also aggravate or lead to serious conditions like fungal infections, sepsis, or tuberculosis. Some cases of cancers have also been reported in children. Patents with serious infections are advised to use it with caution and doctor's prescription.

The drug is especially dangerous for people with chickenpox. It can also lead to nervous system problems such as sclerosis and seizures. It can also weaken the heart and lead to heart problems. It should be avoided by people who are allergic to latex, are pregnant or are planning to do so, have been in close proximity to a person with chicken pox.

In addition to its intended effect, Etacept 25Mg Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Upper respiratory tract infection
Rash
Injection site reaction.
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Etacept 25mg injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
There is no data available. Please consult doctor before consuming the drug.
Does this affect kidney function?
There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which have the same composition, strength and form as Etacept 25Mg Injection, and hence can be used as its substitute.
Intas Pharmaceuticals Ltd
Are there any missed dose instructions?
If you miss a dose of Etanercept, please consult your doctor.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
What are you using Etacept 25Mg Injection for?
Ankylosing Spondylitis
Rheumatoid Arthritis
Psoriasis
Other
How much was the improvement?
Excellent
Average
Poor
How long did it take before seeing improvement?
More than 2 days
Within 6 hours
Within 2 days
Within a day
How frequently did you take this medicine?
Not taking on daily level
Thrice a day
How did you take this medicine?
With Food
Empty stomach
With or without food
What were the side effects of this medicine?
Itching
Other
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I am 37 years old. I am having anklosing spondylitis for. 10 years now i'm taking etacept in fifteen days but I also face tge problem of excessive thirst and dryness what I should do.?

MBBS, MS - Orthopaedics
Orthopedist, Delhi
I have no experience of using etacept injection. Anyway kindly show me digital x rays of affected part. Rule out diabetes & vit. D deficiency or any other metabolic disorder. Sleep on a hard bed with soft bedding on it. Spring beds, folding beds or thick matress are harmful use no pillow under the head. Do hot fomantation. Ibuprofen 200mg od & sos x 5days bio d3 max 1tab od x10 do deep breathing & general exercises. It may have to be further investigated. You will need other supportive medicines also. Make sure you are not allergic to any of the medicines you are going to take. Do reply back for detailed treatment plan. Do not ignore. It could be beginning of a serious problem.
1 person found this helpful

I am suffering frm anklosing spondlities frm ten yrs my Dr. Is Dr. Ashok kumar fortis frm dehli they advice etacept in the duration of fifteen days frm last eight month but now I feel less joint pain but I feel too. Much dry ness in body too much thirst tiredness and pain in head what i do I don't know.

MBBS, MS - Orthopaedics
Orthopedist, Delhi
Kindly show me a photograph & digital x rays of affected part. Rule out diabetes & vit. D deficiency or any other metabolic disorder. Sleep on a hard bed with soft bedding on it. Spring beds, folding beds or thick matress are harmful use no pillow under the head. Do hot fomantation. Ibuprofen 200mg od & sos x 5days. Bio d3 max 1tab od x10. Do neck, back, deep breathing & general exercises. It may have to be further investigated. You will need other supportive medicines also. Make sure you are not allergic to any of the medicines you are going to take. Do reply back for detailed treatment plan. Do not ignore. It could be beginning of a serious problem. Contact me on ph. 9810012688.

Good evening sir, I am suffering from Rheumatoid arthritis 3 year I consult doctor doctor given me sazo 1 GM zyq200'zuvimide100 and and I am very well but before 6 month swelling is start in right knee and I was consult doctor then doctor give me etacept 50 mg injection 6 weak and then we are very well but before 3 month swelling start in right knee again. Then I was consult doctor advised repeat again same medicine please sir help me and advised me please sir.

Bams
Ayurveda, Noida
Good evening sir, I am suffering from Rheumatoid arthritis
 3 year I consult doctor doctor given me sazo 1 GM zyq200'...
In allopathy there is no permanent treatment of this as your age is 22 yr, and recently onset of disease can be cured by ayurveda otherwise it will be difficult to treat ,so first I will tell you this disease is mainly aggrevated by aam formation if you stomach is not clear or motion it occurs again and again so try to take healthy diet, avoid ,chilli, spice,junk food etc, if your digestion is not proper then correct it causes of swelling is many so identify the season or duration, morning or evening stiffness etc, these will correct with yoga asan likeVirasana Malasana Makarasana Utthita Parsvakonasana Parsvottanasana Trikonasana Garudasana etc it helps to reduce swelling and stiffness, use sand fomentation on painful and sweeling joint gives felief from both, or hot fomentation with eranda patra decoction all these remedies gives relef but you have to take panchkarm treatment for permanent solution.

My wife is suffering from Rhemutoid arthritis for 5 yrs. Doctor ne kaha hai etacept injection lene k liye Kay yeh lene k baad mere wife k RA Thik Ho jayega. Aur baad me koi medicine v nhi chalets. Hame ek baby v chahiye usske k liye yeh injection Thik hai. Injection lene k kitne din baad baby le sake hai.

Erasmus Mundus Master in Adapted Physical Activity, MPT, BPTh/BPT
Physiotherapist, Chennai
My wife is suffering from Rhemutoid arthritis for 5 yrs.
Doctor ne kaha hai etacept injection lene k liye Kay yeh len...
Symptoms of rheumatoid arthritis may include painful swelling, inflammation, and stiffness in the fingers, arms, legs, and wrists occurring in the same joints on both sides of the body, especially upon awakening.

Hi sir, I am 32 years old male. I have rheumatoid arthritis. Any medicine for it. and any particular diet.

FRAS, MD - Ayurveda, Bachelor of Ayurveda, Medicine & Surgery (BAMS)
Alternative Medicine Specialist, Ernakulam
Ra can be well managed with ayurveda treatment and pancha karma, consult a ayurveda specialist in your city or come to kerala for authentic ayurveda treatment.
2 people found this helpful

Popular Health Tips

Options Other Than Knee Replacement

MBBS, M. S., SR (AIIMS),FIJRS (SOUTH KOREA)
Orthopedist, Delhi
Options Other Than Knee Replacement

There is no cure for arthritis but there are a number of treatments that may help relieve the pain and disability it can cause.

  • As with other arthritic conditions, initial treatment of arthritis of the knee is nonsurgical. Your doctor may recommend a range of treatment options.
  • Lifestyle modifications. Some changes in your daily life can protect your knee joint and slow the progress of arthritis.
  • Minimize activities that aggravate the condition, such as climbing stairs.
  • Switching from high impact activities (like jogging or tennis) to lower impact activities (like swimming or cycling) will put less stress on your knee.
  • Losing weight can reduce stress on the knee joint, resulting in less pain and increased function.
  • Physical therapy. Specific exercises can help increase range of motion and flexibility, as well as help strengthen the muscles in your leg. Your doctor or a physical therapist can help develop an individualized exercise program that meets your needs and lifestyle.
  • Assistive devices. Using devices such as a cane, wearing shock-absorbing shoes or inserts, or wearing a brace or knee sleeve can be helpful. A brace assists with stability and function, and may be especially helpful if the arthritis is centered on one side of the knee. There are two types of braces that are often used for knee arthritis: an" unloader" brace shifts weight away from the affected portion of the knee, while a" support" brace helps support the entire knee load.
  • Other remedies. Applying heat or ice, using pain-relieving ointments or creams, or wearing elastic bandages to provide support to the knee may provide some relief from pain.
  • Medications. Several types of drugs are useful in treating arthritis of the knee. Because people respond differently to medications, your doctor will work closely with you to determine the medications and dosages that are safe and effective for you.
  • Over-the-counter, non-narcotic pain relievers and anti-inflammatory medications are usually the first choice of therapy for arthritis of the knee. Acetaminophen is a simple, over-the-counter pain reliever that can be effective in reducing arthritis pain.
  • Like all medications, over-the-counter pain relievers can cause side effects and interact with other medications you are taking. Be sure to discuss potential side effects with your doctor.
  • Another type of pain reliever is a nonsteroidal anti-inflammatory drug, or nsaid (pronounced" en-said"). Nsaids, such as ibuprofen and naproxen, are available both over-the-counter and by prescription. A cox-2 inhibitor is a special type of nsaid that may cause fewer gastrointestinal side effects. Common brand names of cox-2 inhibitors include celebrex (celecoxib) and mobic (meloxicam, which is a partial cox-2 inhibitor). A cox-2 inhibitor reduces pain and inflammation so that you can function better. If you are taking a cox-2 inhibitor, you should not use a traditional nsaid (prescription or over-the-counter). Be sure to tell your doctor if you have had a heart attack, stroke, angina, blood clot, hypertension, or if you are sensitive to aspirin, sulfa drugs or other nsaids.
  • Corticosteroids (also known as cortisone) are powerful anti-inflammatory agents that can be injected into the joint these injections provide pain relief and reduce inflammation; however, the effects do not last indefinitely. Your doctor may recommend limiting the number of injections to three or four per year, per joint, due to possible side effects.
  • In some cases, pain and swelling may" flare" immediately after the injection, and the potential exists for long-term joint damage or infection. With frequent repeated injections, or injections over an extended period of time, joint damage can actually increase rather than decrease.
  • Disease-modifying anti-rheumatic drugs (dmards) are used to slow the progression of rheumatoid arthritis. Drugs like methotrexate, sulfasalazine, and hydroxychloroquine are commonly prescribed.
  • In addition, biologic dmards like etanercept (embril) and adalimumab (humira) may reduce the body's overactive immune response. Because there are many different drugs today for rheumatoid arthritis, a rheumatology specialist is often required to effectively manage medications.
  • Viscosupplementation involves injecting substances into the joint to improve the quality of the joint fluid.
  •  Glucosamine and chondroitin sulfate, substances found naturally in joint cartilage, can be taken as dietary supplements. Although patient reports indicate that these supplements may relieve pain, there is no evidence to support the use of glucosamine and chondroitin sulfate to decrease or reverse the progression of arthritis.
5 people found this helpful

Spondyloarthritis

MD
General Physician, Secunderabad
Spondyloarthritis

Spondyloarthritis (also known as spondyloarthropathy) is the term which describes the connective tissue diseases. It is the group of inflammatory diseases, including arthritis of the peripheral joints and spine (sacroiliitis or spondylitis); including the area where ligaments and tendons attach to bones (enthesitis or enthesopathy). These diseases cause pain or stiffness in the leg or arm joints, spine, ligaments and tendons become inflamed. Skin rashes, eye, and intestinal problems may also be able to occur.

Epidemiology

  • Spondyloarthritis is a pathology that specifically strikes young people. The symptoms most frequently start before the age of 45. It affects more males than females.
  • Predisposition to spondyloarthritis, especially spa, is determined largely by genetic factors.
  • The incidence rate is higher in populations with a higher prevalence of hla-b27.
  • Psoriatic skin lesions and colitis due to inflammatory bowel disease (ibd) have been considered as both basic, subtype-defining entities with their own genetic background (distinct from hla-b27 genotype), and as manifestations of spondyloarthritis.
  • There is a strong need to diagnose patients with spa in an earlier stage; currently, there is a delay of 5–10 years between onset of the first symptoms and diagnosis.

Types

There are five types of spondyloarthritis

Ankylosing spondylitis or bechterew disease: it is the type of arthritis that affects the spine. Symptoms include pain and stiffness in the lower back and in the neck. Spine bones fuse together and it will become rigid spine and it leads to stoope over posture.

Psoriatic arthritis: psoriatic arthritis is the form of arthritis that affects the people who have psoriasis. Most people diagnosed with psoriasis and later diagnosed with psoriatic arthritis. It may affect any part of the body such as fingertips and spine. The main symptoms are joint pain, stiffness, and swelling.

Psoriatic arthritis

Reactive arthritis: it occurs due to the infection by certain bacteria. Often the bacteria’s from genitals (chlamydia trachomatis) or bowel (campylobacter, salmonella, shigella, and yersinia). It usually targets your knees and joints of ankles or feet.

Reactive arthritis

Undifferentiated arthritis: undifferentiated inflammatory arthritis does not conform to any of the recognized inflammatory arthritis types. It may include monoarthritis of a single joint; oligoarthritis, which is usually when four or fewer joints are involved; or polyarthritis, which usually involves many small joints.

Risk factors

Risk factors may be higher due to following reasons:

  • Family member having the gene which causes spondyloarthritis
  • Positive results for the hla-b27 gene
  • Recurring bacterial infection in your gut
  • Have other inflammatory conditions such as psoriasis or inflammatory bowel disease

Causes

  • The main cause is not known, but researchers pointed out that the hereditary genetics playing an important role in this disease. Since this disease occurs often in family members of patients who have spondyloarthritis.
  • Many genes cause it. Up to 30 genes have been found. But the major gene that causes spondyloarthritis is hla-b27.
  • Bacterial infections can also cause reactive spondyloarthritis known to be triggered by a bacteria chlamydia or food borne infections.

Symptoms and complications of spondyloarthritis

The first and major symptoms of all types of spondyloarthritis are severe low back pain, swelling of arms, stiffness, and fatigue. The different types of spondyloarthritis can be manifested by the following signs and symptoms.

  • Alternative or unilateral buttock pain
  • Arthritis in small joints
  • Arthritis in large joints such as knee joint, ankle joint and elbow joint (peripheral arthritis)
  • Numbness and tingling sensation in arms and legs
  • Spinal fusion may occur in ankylosing spondylitis
  • Inflammation at the interfaces between bone and tendon or ligament of limbs (enthesitis)
  • Inflammation of intestine, urinary tract and aortic heart valves. These can lead to spinal joints inflammation.
  • Inflammation of joints in pelvis and spine (sacroiliitis)
  • Enteropathic arthritis shows symptoms such as diarrhea and abdominal pain
  • Digestive problems
  • Skin disease like psoriasis
  • Osteoporosis
  • Redness of eye (iritis)
  • Swollen fingers and
  • Pain in the heels cause difficult to walk, stand even for small duration

Diagnosis and testing

First a doctor may ask for patient’s medical history, physical exam and may suspects for symptoms of spondyloarthritis. To confirm doctor may perform the following diagnosis and tests.

  • X-rays: x-ray images shows the change of the sacroiliac joints in the pelvis and fusion of spine. If these changes not observed, but symptoms shows spondyloarthritis doctor will suggest mri scan. Mri shows these changes more promptly than the x-ray.
  • Mri scans: it can show a very clear image of enthesitis and also the changes of sacroiliac joints.
  • Ct scans: ct also used for the imaging of bone joints.
  • Hla-b27: most patients with spondyloarthritis have hla-b27 gene, but some people don’t have this gene. So it is necessary to go for a hla-b27 test if the symptoms suspects spondyloarthritis.
  • Complete blood count (cbc): cbc can be useful to find the inflammation.
  • Musculoskeletal ultrasound scanning: ultrasound imaging uses sound waves to produce the images of inflammatory conditions of muscles, ligaments, and tendons.
  • Dual-energy x-ray absorptiometry (dexa) scans: used for measuring the bone mineral density usually the bones of the lower spine and hips. Bone loss is measured through this technique.

Treatment of spondyloarthritis.

  • There is no way to cure this disease condition, but there are treatments to counterparts the symptoms.
  • Nonsteroidal anti-inflammatory drugs: certain nsaid’s like naproxen, ibuprofen, meloxicam, or indomethacin are prescribed by doctors to relief from the pain due to symptoms.
  • Corticosteroid medication: inflammation around the tendons and in the joints can be overcome by taking some corticosteroid drugs. This helps to reduce the swelling in the joints.
  • Antibiotics: antibiotics can be used in the case of reactive spondyloarthritis in which bacteria cause the major problems.
  • Disease-modifying antirheumatic drugs (dmard’s): sulfasalazine (azulfidine) and methotrexate are the best dmard’s to be used for the joint damages in limbs affected by arthritis.
  • Tumor necrosis alpha (tnf-alpha) blockers: fda approved tnab are adalimumab (humira), adalimumab-atto (amjevita), a biosimilar to humira, certolizumab pegol (cimzia), etanercept (enbrel), etanercept-szzs (ereizi), a biosimilar to enbrel, golimumab (simponi), infliximab (remicade), infliximab-dyyb (inflectra), a biosimilar to remicade, and secukinimab (cosentyx). These are biosimilars used to treat arthritis in spine joints.
  • Surgery: patients with over inflammation of pelvis joints needs hip replacement. In the case of heavy damage in the cartilage of joints needs surgery to repair. In some rare cases, spinal surgery also needed.

Prevention and control measures

  • Prevention from spondyloarthritis needed some lifestyle changes as follows.
  • Quit smoking: smoking speeds up the spinal fusion in addition to other bad health effects.
  • Follow good posture: practicing a proper sitting and posture makes your spine to escape from growing into slumped-over position and strain.
  • Daily physical exercise: frequent home exercise and physiotherapy is essential to reduce the stiffening of spine and other joint problems. It also helps to have your heart healthy.
  • Good diet: follow the diets that are rich in calcium. Dairy products are preferred foe calcium rich foods.
Psoriatic arthritis
3 people found this helpful

Rheumatoid Arthritis!

MD - Acupuncture, Diploma In Accupuncture, Advanced Diploma In Accupuncture
Acupuncturist, Delhi
Rheumatoid Arthritis!

Rheumatoid Arthritis 

Treatment of Rheumatoid arthritis
Homeopathic Treatment of Rheumatoid arthritis
Acupuncture & Acupressure Treatment of Rheumatoid arthritis
Psychotherapy Treatment of Rheumatoid arthritis
Conventional / Allopathic Treatment of Rheumatoid arthritis
Surgical Treatment of Rheumatoid arthritis
Dietary & Herbal Treatment of Rheumatoid arthritis
Other Treatment of Rheumatoid arthritis
What is Rheumatoid arthritis
Symptoms of Rheumatoid arthritis
Causes of Rheumatoid arthritis
Risk factors of Rheumatoid arthritis
Complications of Rheumatoid arthritis
Lab Investigations and Diagnosis of Rheumatoid arthritis
Precautions & Prevention of Rheumatoid arthritis
Treatment of Rheumatoid arthritis

Homeopathic Treatment of Rheumatoid arthritis

Homeopathy is extremely successful in treating rheumatoid arthritis. Homeopathic treatment gives relief in arthritis with inflammation, pain, stiffness and lameness. It is useful in preventing and treating deformities associated with the disease. Some of the homeopathic remedies that can be used for treatment of rheumatoid arthritis are:

Arnica
Bryonia
Calcarea
Causticum
Chinin s
Dulcamara
Kali carb
Pulsatilla
 

Acupuncture & Acupressure Treatment of Rheumatoid arthritis

The acupuncture and acupressure stimulate dilation of the blood vessels, potentially reducing swelling and pain. Acupuncture and Acupressure helps in nourishing the tendons and joints. It also has a strong effect on promoting the smooth flow of chi throughout the body. Obstruction to the smooth flow of chi causes pain and discomfort. Acupuncture gives lasting relief in rheumatoid arthritis.

Psychotherapy and Hypnotherapy Treatment of Rheumatoid arthritis

Psychotherapy and hypnotherapy can help in stress relief. They can help in better coping and early relief.

Conventional / Allopathic Treatment of Rheumatoid arthritis

Allopathic Treatment of Rheumatoid arthritis involves the following medications:

NSAIDs – ibuprofen and naproxen
Steroids – prednisone
DMARDs – leflunomide and hydroxychloroquine
Immunosuppressants – cyclosporine and cyclophosphamide
TNF-alpha inhibitors – etanercept and infliximab
 

Surgical Treatment of Rheumatoid arthritis

Surgical Treatment of Rheumatoid arthritis involves the following surgeries:

Total joint replacement
Tendon repair
Joint fusion
 

Dietary & Herbal Treatment of Rheumatoid arthritis

Eat foods rich in omega-3 fatty acid such as soybeans, walnuts and avocados
Avoid saturated fats
Avoid fried and grilled food
Avoid tea and coffee
 

Other Treatment of Rheumatoid arthritis

Heat compresses relax your muscles and stimulate blood flow
Applying cold also decreases muscle spasms.
 

What is Rheumatoid arthritis

Rheumatoid arthritis (RA) is a form of arthritis that causes pain, swelling, stiffness and loss of function in your joints. Hands, feet and wrists are commonly affected, but it can also damage other parts of the body.

Symptoms of Rheumatoid arthritis

Swollen joints
Pain in the joints
Fatigue
Fever
Weight loss
Morning stiffness
 

Causes of Rheumatoid arthritis

The exact cause of rheumatoid arthritis is unknown.

Risk factors of Rheumatoid arthritis

More common in women
Between the ages of 40 and 60
Cigarette smoking
Family history
 

Complications of Rheumatoid arthritis

Carpal tunnel syndrome
Heart problems
Lung disease
Deformities
Osteoporosis
 

Diagnosis of Rheumatoid arthritis

Diagnosis of Rheumatoid arthritis involves the following tests:

Physical exam
Blood tests
X-rays
 

Precautions & Prevention of Rheumatoid arthritis

You can gain control of rheumatoid arthritis and improve your chances by taking the following steps:

Get the treatment early
Avoid exercising tender, injured or severely inflamed joints
Rest when you need to
Use a cane in the hand opposite a painful hip or knee