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Overview

Diltigesic 2% Cream

Manufacturer: Troikaa Pharmaceuticals Ltd
Medicine composition: Diltiazem
Prescription vs.OTC: Prescription by Doctor required

Diltigesic 2% Cream obstructs calcium function, to effectively relax heart muscles and blood vessels. The drug is prescribed to patients who suffer from high blood pressure issues or have angina. Patients with various disorders of the heart rhythm may also be prescribed Diltigesic 2% Cream. The medicine is taken orally and the dosage should be strictly taken according to the prescription. This is primarily because Diltigesic 2% Cream can cause certain side effects, which may aggravate if the dosage is not right. Some side effects of Diltigesic 2% Cream are-

Other side effects may also occur, in which case a doctor should be immediately considered.

The medicine is generally not prescribed to patients with severe heart problems, for instance an AV block or suffer from hypotension. It is also not recommended for patients who have had a heart attack very recently. Doctors should be informed about any kidney problems, liver disease or allergies to make sure that the drug is safe for consumption. It is also not recommended for pregnant women or mothers who are breast feeding, unless absolutely essential. It is available either in the form of a table or a capsule, the drug is meant to be taken orally. Stopping the medicine suddenly can lead to severe consequences. In case the drug needs to be stopped it should be done gradually. It is always best that patients on Diltigesic 2% Cream keep checking their blood pressure to ensure that it is at the desired level. Diltigesic 2% Cream should be stored at room temperature and kept away from heat as well as moisture. An over dose of the drug can be highly fatal. Emergency medical aid should be acquired in this case.

Diltigesic 2% Cream is used in the treatment of hypertension which is an increase in the blood pressure caused by genetic and environmental factors.
Angina Pectoris Prophylaxis
Diltigesic 2% Cream is used in the treatment of angina pectoris which is a type of heart disease characterized by chest pain caused due to emotional stress and smoking.
Diltigesic 2% Cream is used in the treatment of atrial fibrillation which is a type of heart disease characterized by irregular and fast heart rate.
Supraventricular Tachycardia
Diltigesic 2% Cream is used in the treatment of supraventricular tachycardia which is a type of heart disease characterized by fast heartbeat.
Avoid if you have a known allergy to Diltigesic 2% Cream or any medicine belongs to the class calcium channel blockers.
Hypotension
This medicine is not recommended in the patients with the systolic blood pressure less than 90 mm Hg.
This medicine is not recommended in the patients with known case of myocardial infarction.
This medicine is not recommended in the patients with sick sinus syndrome except in the presence of a functioning ventricular pacemaker.
In addition to its intended effect, Diltigesic 2% Cream may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Body pain Major Common
Cough Major Common
Fever Major Common
Chest discomfort Major Less Common
Headache Major Less Common
Diarrhea Major Less Common
Swelling of the hands, ankles, feet, or lower legs Major Less Common
Sneezing Minor Common
Acid or sour stomach Minor Less Common
Constipation Minor Less Common
Muscle pain Minor Less Common
Skin rash Minor Less Common
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 9 to 12 hours for an immediate release tablet, 12 to 24 hours for an extended release tablet, 15 to 30 hours for an extended release capsule, 9 to 12 hours for a single intravenous dose, 12 to 15 hours for an infusion.
What is the onset of action?
The peak effect of this medicine can be observed in 2 to 4 hours for an immediate release tablet, 11 to 18 hours for an extended release tablet and 10 to 14 hours for an extended release capsule.
Are there any pregnancy warnings?
This medicine is not recommended for pregnant women. Use under the supervision of the doctor, only if clinical condition clearly requires the use of this medicine.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
This medicine is not recommended for breastfeeding women. Use only if clearly needed under the doctor's supervision. Monitoring of blood pressure is necessary.
Missed Dose instructions
The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of an overdose.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Aortic Stenosis Major
Diltigesic 2% Cream is not recommended in the patients with aortic stenosis as it may worsen the myocardial oxygen balance.
Interaction with Alcohol
Alcohol Moderate
Consumption of alcohol should be avoided while taking this medicine, especially when you start taking the medicine or a change its dosage. Symptoms like headache, dizziness, change in pulse or heart rate should be reported to the doctor.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Carbamazepine Major
Combined use of these medicines is not recommended due to changes in the levels of these medicines. Any symptoms of headache, dizziness, visual disturbances should be reported to the doctor. Dose adjustments are to be made based on the clinical condition or an alternate medicine should be considered.
Itraconazole Major
Combined use of these medicines is not recommended due to changes in the levels of Diltigesic 2% Cream. Any symptoms of swelling of hands, feet, dizziness should be reported to the doctor. Avoid operating machinery and driving vehicle. Dose adjustments are to be made based on the clinical condition or an alternate medicine should be considered.
Ethinyl Estradiol Moderate
The blood levels of oral contraceptives may increase if taken with Diltigesic 2% Cream. Dose adjustments are to be based on the clinical condition or an alternate medicine should be considered.
Atorvastatin Moderate
These medicines should be used with caution due to increase in the levels of atorvastatin which may cause severe muscle injury. Frequent monitoring of kidney function tests is necessary. Any symptoms of muscle pain, tenderness, dark colored urine should be reported to the doctor. Dose adjustments or an alternate medicine should be considered based on the clinical condition.
What are you using Diltigesic 2% Cream for?
Other
How much was the improvement?
Average

Popular Questions & Answers

I am 46 years and I have this recurring anal fissure, I have tried diltigesic cream and anusol inserts, but it comes back again when the medication is over.

M.S. (Ayurveda), Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Ayurveda, Delhi
You need proper Kshar Karma sittings in which a specific Kshar medicines are applied over the anal fissure under medical supervision. The sittings are conducted at weekly intervals. Fissure heals completely in 4-5 sittings. For more information please contact through Lybrate or visit clinic.

I have recurring anal fissures, I have tried anal inserts recently a doctor gave me Diltigesic cream to apply, they disappeared for two weeks, now the pain is back again kindly I need help.

MS - General Surgery, FMAS.Laparoscopy
General Surgeon, Gandhinagar
Hello dear Lybrate user, hi Warm welcome to Lybrate.com I have evaluated your query thoroughly. Anal fissures are known to get on and off presentation only you can keep it under control with medicines, ointmnent,sitz bath, dietary measures, quitting smoking if doing Hope this clears your query. Wishing you fine recovery. Welcome for any further assistance at my private URL https://www.Lybrate.com/gandhinagar/doctor/dr-bhagyesh-patel-general-surgeon Regards take care.
1 person found this helpful

Hi, Respected Doctor confirms anal fissure with sentinel piles. Advised Diltigesic Cream application. I feel itching sensation when applied. Is it normal?

MCh(Minimally Invasive & Robotic Surgery), MS - Surgical, MBBS
General Surgeon, Guwahati
Ya. It is fine. Try to take hot sitz bath with Betadine solution twice daily. Please rem that Diltigesic oint may cause mild headache which is normal.

I have been suffering from recurring anal fissure since last 6-7 months. It started earlier around 6-7 months back and got healed properly after taking Diltigesic ointment. But it strike once again. I have been applying Diltigesic but its like after application it become fine. But whenever I defecate itching and pain start once again. I am having a small tear on a anal passage opening. Never had constipation. So I wish to consult that what's the permanent solution to get rid of this anal fissures. Looking forward for quick response.

MS - General Surgery, FMAS.Laparoscopy
General Surgeon, Gandhinagar
I have been suffering from recurring anal fissure since last 6-7 months. It started earlier around 6-7 months back an...
Respected lybrate-user hi avoiding friction through hard stool is the only way for it. Cases have been reported recurrence after surgery so I would advise surgery as last resort only. Take more liquids green leafy veg fiber fruits curd avoid oily spicy nonveg stuffs. Can take analgesics for more pain & sitz bath as usual to get early cure thanks regards.
1 person found this helpful

Popular Health Tips

Pulmonary Hypertension - What Type Of Treatment Is Given?

MD , MBBS
Pulmonologist, Delhi
Pulmonary Hypertension - What Type Of Treatment Is Given?

Pulmonary hypertension mainly occurs due to narrowing of the arteries of the lungs as a result of which the flow of blood is restricted. In this kind of condition, blood fails to carry oxygen to your heart and thus your heart gets adversely affected. The blood pressure of your body will get increased to a great extent if this situation remains untreated, thus leading to bdreadful consequenses, specifically situation like heart failure, serious pulmonary diseases, blood clots in lungs and congenial heart defects, etc.

There are certain forms of pulmonary hypertension, which are serious in nature and worsen with time, so much so that they are even fatal at times. It also includes forms which are non curable in nature, however, in order to improve the quality of life, symptoms can be reduced with proper treatment. The treatment for pulmonary hypertension is often complex and it takes some time to find the most appropriate treatment and requires extensive follow-up care. Your doctor might also need to change your treatment if it's no longer effective. However, when pulmonary hypertension is caused by another condition, your doctor will treat the underlying cause whenever possible.

Common Treatments for pulmonary hypertension:

Medications:

  1. Blood vessel dilators (vasodilators): Vasodilators open narrowed blood vessels. They are one of the most commonly prescribed vasodilators for pulmonary hypertension is epoprostenol (Flolan, Veletri). The drawback to epoprostenol is that the effect lasts only for few minutes. This drug is continuously injected through an intravenous (IV) catheter via a small pump that you wear in a pack on your belt or shoulder.
  2. Ventavis: Another form of the drug, iloprost (Ventavis), can be inhaled six to nine times a day through a nebulizer, a machine that vaporizes your medication. Because it's inhaled, it goes directly to the lungs.
  3. Treprostinil (Tyvaso, Remodulin, Orenitram): It is another form of the drug, which can be given four times a day and can be inhaled or can be taken as an oral medication and can also be administered through injection.
  4. Endothelin receptor antagonists: These medications reverse the effect of endothelin, a substance in the walls of blood vessels that causes them to narrow. These drugs may improve your energy level and symptoms. However, these drugs shouldn't be taken if you're pregnant. Also, these drugs can damage your liver and you may need monthly liver monitoring.
  5. Sildenafil and tadalafil: Sildenafil (Revatio, Viagra) and tadalafil (Cialis, Adcirca) are sometimes used to treat pulmonary hypertension. These drugs work by opening the blood vessels in the lungs to allow blood to flow through more easily.
  6. High-dose calcium channel blockers: These drugs help relax the muscles in the walls of your blood vessels. They include medications, such as amlodipine (Norvasc), diltiazem (Cardizem, Tiazac, others) and nifedipine (Procardia, others). Although calcium channel blockers can be effective, only a small number of people with pulmonary hypertension respond to them.
  7. Soluble guanylate cyclase (SGC) stimulator: Soluble guanylate cyclase (SGC) stimulators (Adempas) interact with nitric oxide and help relax the pulmonary arteries and lower the pressure within the arteries. These medications should not be taken if you're pregnant. They can sometimes cause dizziness or nausea.
  8. Anticoagulants: Your doctor is likely to prescribe the anticoagulant warfarin (Coumadin, Jantoven) to help prevent the formation of blood clots within the small pulmonary arteries. Because anticoagulants prevent normal blood coagulation, they increase your risk of bleeding complications. Take warfarin exactly as prescribed, because warfarin can cause severe side effects if taken incorrectly. If you're taking warfarin, your doctor will ask you to have periodic blood tests to check how well the drug is working. Many other drugs, herbal supplements and foods can interact with warfarin, so be sure your doctor knows all of the medications you're taking.
  9. Digoxin: Digoxin (Lanoxin) can help the heart beat stronger and pump more blood. It can help control the heart rate if you experience arrhythmias.
  10. Diuretics: Commonly known as water pills, these medications help eliminate excess fluid from your body. This reduces the amount of work your heart has to do. They may also be used to limit fluid buildup in your lungs.
  11. Oxygen: Your doctor might suggest that you sometimes breathe pure oxygen, a treatment known as oxygen therapy, to help treat pulmonary hypertension, especially if you live at a high altitude or have sleep apnea. Some people who have pulmonary hypertension eventually require continuous oxygen therapy.

Surgeries:

  1. Atrial Septostomy: If medications don't control your pulmonary hypertension, this open heart surgery might be an option. In an atrial septostomy, a surgeon will create an opening between the upper left and right chambers of your heart (atria) to relieve the pressure on the right side of your heart.
  2. Lung Transplantation: In some cases, a lung or heart lung transplant might be an option, especially for younger people who have idiopathic pulmonary arterial hypertension.

Reducing Complications:

  1. The complications need to be reduced by taking proper health care. Healthy diet needs to be taken regularly along with proper medications. Smoking should be stopped and exercising sessions should be attended daily without any fail
  2. Overweight or obesity needs to be controlled properly for reducing the complications. Specialized caring strategies need to be maintained for avoiding severe kinds of health complications that are quite annoying. If you wish to discuss about any specific problem, you can consult a Pulmonologist.
2492 people found this helpful

Pulmonary Hypertension: How to Treat It?

MD - Pulmonary, DTCD
Pulmonologist, Faridabad
Pulmonary Hypertension: How to Treat It?

Pulmonary hypertension mainly occurs due to narrowing of the arteries of the lungs as a result of which the flow of blood is restricted. In this kind of condition, blood fails to carry oxygen to your heart and thus your heart gets adversely affected. The blood pressure of your body will get increased to a great extent if this situation remains untreated, thus leading to bdreadful consequenses, specifically situation like heart failure, serious pulmonary diseases, blood clots in lungs and congenial heart defects, etc.

There are certain forms of pulmonary hypertension, which are serious in nature and worsen with time, so much so that they are even fatal at times. It also includes forms which are non curable in nature, however, in order to improve the quality of life, symptoms can be reduced with proper treatment. The treatment for pulmonary hypertension is often complex and it takes some time to find the most appropriate treatment and requires extensive follow-up care. Your doctor might also need to change your treatment if it's no longer effective. However, when pulmonary hypertension is caused by another condition, your doctor will treat the underlying cause whenever possible.

Common Treatments for pulmonary hypertension:

Medications:

  1. Blood vessel dilators (vasodilators): Vasodilators open narrowed blood vessels. They are one of the most commonly prescribed vasodilators for pulmonary hypertension is epoprostenol (Flolan, Veletri). The drawback to epoprostenol is that the effect lasts only for few minutes. This drug is continuously injected through an intravenous (IV) catheter via a small pump that you wear in a pack on your belt or shoulder.
  2. Ventavis: Another form of the drug, iloprost (Ventavis), can be inhaled six to nine times a day through a nebulizer, a machine that vaporizes your medication. Because it's inhaled, it goes directly to the lungs.
  3. Treprostinil (Tyvaso, Remodulin, Orenitram): It is another form of the drug, which can be given four times a day and can be inhaled or can be taken as an oral medication and can also be administered through injection.
  4. Endothelin receptor antagonists: These medications reverse the effect of endothelin, a substance in the walls of blood vessels that causes them to narrow. These drugs may improve your energy level and symptoms. However, these drugs shouldn't be taken if you're pregnant. Also, these drugs can damage your liver and you may need monthly liver monitoring.
  5. Sildenafil and tadalafil: Sildenafil (Revatio, Viagra) and tadalafil (Cialis, Adcirca) are sometimes used to treat pulmonary hypertension. These drugs work by opening the blood vessels in the lungs to allow blood to flow through more easily.
  6. High-dose calcium channel blockers: These drugs help relax the muscles in the walls of your blood vessels. They include medications, such as amlodipine (Norvasc), diltiazem (Cardizem, Tiazac, others) and nifedipine (Procardia, others). Although calcium channel blockers can be effective, only a small number of people with pulmonary hypertension respond to them.
  7. Soluble guanylate cyclase (SGC) stimulator: Soluble guanylate cyclase (SGC) stimulators (Adempas) interact with nitric oxide and help relax the pulmonary arteries and lower the pressure within the arteries. These medications should not be taken if you're pregnant. They can sometimes cause dizziness or nausea.
  8. Anticoagulants: Your doctor is likely to prescribe the anticoagulant warfarin (Coumadin, Jantoven) to help prevent the formation of blood clots within the small pulmonary arteries. Because anticoagulants prevent normal blood coagulation, they increase your risk of bleeding complications. Take warfarin exactly as prescribed, because warfarin can cause severe side effects if taken incorrectly. If you're taking warfarin, your doctor will ask you to have periodic blood tests to check how well the drug is working. Many other drugs, herbal supplements and foods can interact with warfarin, so be sure your doctor knows all of the medications you're taking.
  9. Digoxin: Digoxin (Lanoxin) can help the heart beat stronger and pump more blood. It can help control the heart rate if you experience arrhythmias.
  10. Diuretics: Commonly known as water pills, these medications help eliminate excess fluid from your body. This reduces the amount of work your heart has to do. They may also be used to limit fluid buildup in your lungs.
  11. Oxygen: Your doctor might suggest that you sometimes breathe pure oxygen, a treatment known as oxygen therapy, to help treat pulmonary hypertension, especially if you live at a high altitude or have sleep apnea. Some people who have pulmonary hypertension eventually require continuous oxygen therapy.

Surgeries:

  1. Atrial Septostomy: If medications don't control your pulmonary hypertension, this open heart surgery might be an option. In an atrial septostomy, a surgeon will create an opening between the upper left and right chambers of your heart (atria) to relieve the pressure on the right side of your heart.
  2. Lung Transplantation: In some cases, a lung or heart lung transplant might be an option, especially for younger people who have idiopathic pulmonary arterial hypertension.

Reducing Complications:

  1. The complications need to be reduced by taking proper health care. Healthy diet needs to be taken regularly along with proper medications. Smoking should be stopped and exercising sessions should be attended daily without any fail
  2. Overweight or obesity needs to be controlled properly for reducing the complications. Specialized caring strategies need to be maintained for avoiding severe kinds of health complications that are quite annoying.
8721 people found this helpful

How To Treat Pulmonary Hypertension?

DTCD (TDD), C-HIV
Pulmonologist, Pune
How To Treat Pulmonary Hypertension?

Pulmonary hypertension mainly occurs due to narrowing of the arteries of the lungs as a result of which the flow of blood is restricted. In this kind of condition, blood fails to carry oxygen to your heart and thus your heart gets adversely affected. The blood pressure of your body will get increased to a great extent if this situation remains untreated, thus leading to bdreadful consequenses, specifically situation like heart failure, serious pulmonary diseases, blood clots in lungs and congenial heart defects, etc.

There are certain forms of pulmonary hypertension, which are serious in nature and worsen with time, so much so that they are even fatal at times. It also includes forms which are non curable in nature, however, in order to improve the quality of life, symptoms can be reduced with proper treatment. The treatment for pulmonary hypertension is often complex and it takes some time to find the most appropriate treatment and requires extensive follow-up care. Your doctor might also need to change your treatment if it's no longer effective. However, when pulmonary hypertension is caused by another condition, your doctor will treat the underlying cause whenever possible.

Common Treatments for pulmonary hypertension:

Medications:

  1. Blood vessel dilators (vasodilators): Vasodilators open narrowed blood vessels. They are one of the most commonly prescribed vasodilators for pulmonary hypertension is epoprostenol (Flolan, Veletri). The drawback to epoprostenol is that the effect lasts only for few minutes. This drug is continuously injected through an intravenous (IV) catheter via a small pump that you wear in a pack on your belt or shoulder.
  2. Ventavis: Another form of the drug, iloprost (Ventavis), can be inhaled six to nine times a day through a nebulizer, a machine that vaporizes your medication. Because it's inhaled, it goes directly to the lungs.
  3. Treprostinil (Tyvaso, Remodulin, Orenitram): It is another form of the drug, which can be given four times a day and can be inhaled or can be taken as an oral medication and can also be administered through injection.
  4. Endothelin receptor antagonists: These medications reverse the effect of endothelin, a substance in the walls of blood vessels that causes them to narrow. These drugs may improve your energy level and symptoms. However, these drugs shouldn't be taken if you're pregnant. Also, these drugs can damage your liver and you may need monthly liver monitoring.
  5. Sildenafil and tadalafil: Sildenafil (Revatio, Viagra) and tadalafil (Cialis, Adcirca) are sometimes used to treat pulmonary hypertension. These drugs work by opening the blood vessels in the lungs to allow blood to flow through more easily.
  6. High-dose calcium channel blockers: These drugs help relax the muscles in the walls of your blood vessels. They include medications, such as amlodipine (Norvasc), diltiazem (Cardizem, Tiazac, others) and nifedipine (Procardia, others). Although calcium channel blockers can be effective, only a small number of people with pulmonary hypertension respond to them.
  7. Soluble guanylate cyclase (SGC) stimulator: Soluble guanylate cyclase (SGC) stimulators (Adempas) interact with nitric oxide and help relax the pulmonary arteries and lower the pressure within the arteries. These medications should not be taken if you're pregnant. They can sometimes cause dizziness or nausea.
  8. Anticoagulants: Your doctor is likely to prescribe the anticoagulant warfarin (Coumadin, Jantoven) to help prevent the formation of blood clots within the small pulmonary arteries. Because anticoagulants prevent normal blood coagulation, they increase your risk of bleeding complications. Take warfarin exactly as prescribed, because warfarin can cause severe side effects if taken incorrectly. If you're taking warfarin, your doctor will ask you to have periodic blood tests to check how well the drug is working. Many other drugs, herbal supplements and foods can interact with warfarin, so be sure your doctor knows all of the medications you're taking.
  9. Digoxin: Digoxin (Lanoxin) can help the heart beat stronger and pump more blood. It can help control the heart rate if you experience arrhythmias.
  10. Diuretics: Commonly known as water pills, these medications help eliminate excess fluid from your body. This reduces the amount of work your heart has to do. They may also be used to limit fluid buildup in your lungs.
  11. Oxygen: Your doctor might suggest that you sometimes breathe pure oxygen, a treatment known as oxygen therapy, to help treat pulmonary hypertension, especially if you live at a high altitude or have sleep apnea. Some people who have pulmonary hypertension eventually require continuous oxygen therapy.

Surgeries:

  1. Atrial Septostomy: If medications don't control your pulmonary hypertension, this open heart surgery might be an option. In an atrial septostomy, a surgeon will create an opening between the upper left and right chambers of your heart (atria) to relieve the pressure on the right side of your heart.
  2. Lung Transplantation: In some cases, a lung or heart lung transplant might be an option, especially for younger people who have idiopathic pulmonary arterial hypertension.

Reducing Complications:

  1. The complications need to be reduced by taking proper health care. Healthy diet needs to be taken regularly along with proper medications. Smoking should be stopped and exercising sessions should be attended daily without any fail
  2. Overweight or obesity needs to be controlled properly for reducing the complications. Specialized caring strategies need to be maintained for avoiding severe kinds of health complications that are quite annoying. If you wish to discuss about any specific problem, you can consult a Pulmonologist.
1872 people found this helpful

Table of Content

About Diltigesic 2% Cream
When is Diltigesic 2% Cream prescribed?
What are the contraindications of Diltigesic 2% Cream?
What are the side effects of Diltigesic 2% Cream?
Key highlights of Diltigesic 2% Cream
What are the dosage instructions?
Where is the Diltigesic 2% Cream approved?
What are the interactions for Diltigesic 2% Cream?