Alemtuzumab

Alemtuzumab is a drug used in the treatment of chronic lymphocytic leukemia (CLL), cutaneous T-cell lymphoma (CTCL) and T-cell lymphoma. It is also used in some conditioning regimens for bone marrow transplantation, kidney transplantation and islet cell transplantation. It is also used to treat a certain type of multiple sclerosis.

Alemtuzumab is not a traditional chemotherapy medication; it is in a class of medications called monoclonal antibodies, a type of targeted therapy.Traditional chemotherapy drugs identify cancer cells by their rapid rate of reproduction, and then attack those cells. Unfortunately, there are also cells in our bodies that normally reproduce rapidly and these cells are also affected by traditional chemotherapy drugs.

Alemtuzumab is used to treat leukemia by exploiting antibody mediated lysis of CD52 presenting cells. The CD52 antigen is a cell surface protein found on essentially all B and T lymphocytes, a majority of monocytes, macrophages and most granulocytes. The CD52 antigen is not present on erythrocytes or hematopoetic stem cells. In leukemia there is an excess of B and T cells, so Campath permits selective reduction of lymphocyte populations.

SIDE EFFECTS :

• Cough
• Bronchitis (see lung problems)
• Muscle pain
• Poor appetite
• Sweating (see skin reactions)
• Headache
• Numbness in the hands or feet
• Mouth sores
• Weakness
• Swelling of the hands or feet
• Sore throat (see cold symptoms)
• Dizziness
• High blood pressure
• Abdominal pain
• Chest pain
• Heartburn
• Back pain

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of alemtuzumab, there are no specific foods that you must exclude from your diet.Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if alemtuzumab passes into your breast milk. You and your doctor should decide whether you will stop breastfeeding or not take alemtuzumab.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Blood Cancer

• Multiple Sclerosis (Ms)

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Rash

• Headache

• Insomnia (Difficulty In Sleeping)

• Nausea

• Upper Respiratory Tract Infection

• Decreased White Blood Cell Count

• Fatigue

• Fever

• Itching

• Flushing

• Urticaria

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Alemtuzumab may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Alemtuzumab is probably usafe to use during lactation. \nLimited human data suggests that the drug could represent a significant risk to the baby.

• Is it safe to drive while on this medicine?

  Alemtuzumab may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

• Does this affect kidney function?

  There is limited information available on the use of Alemtuzumab in patients with kidney disease. Please consult your doctor.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose of Alemtuzumab, please consult your doctor.\n

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

Below is the list of medicines, which contains Alemtuzumab as ingredient

• Campath 30mg Injection

  Zydus Cadila

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

Alemtuzumab is a monoclonal antibody which specifically binds CD52 antigen found on all B and T lymphocytes called, leading to lysis of these cells. Excess of B and T lymphocytes in leukemia allows their population to be reduced by this drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.