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Overview

Azifast 2 % Gel

Manufacturer :  Ipca Laboratories Pvt Ltd.
Medicine Composition :  Azithromycin
Prescription vs OTC : Prescription by Doctor required

About Azifast 2 % Gel

Azifast 2 % Gel is an antibiotic used to treat different types of infections caused by a variety of bacteria. It belongs to a group of Macrolide Antibiotics useful for treating numerous infections caused by bacteria like middle ear infections, traveler’s diarrhea.

It is prescribed for the treatment of mild to moderate upper and lower respiratory tract infections, infections of the skin and skin structure. The medication also helps against number of intestinal infections and sexually transmitted infections including gonorrhea and chlamydia.

You should not consume the tablet without consulting a doctor if you have:

Few common side effects of this tablet include nausea, vomiting, stomach upset and diarrhoea. An allergic reaction can also occur in rare cases. The dosage will depend on your age, the severity of condition, medical history and how you react to the first dose.

It is also used for preventing or delaying the onset of infection with Mycobacterium avium complex (MAC). Also, prescribed for prophylaxis of bacterial endocarditis in patients who are allergic to penicillin and undergoing surgical or dental procedures.

Along with other medications, it is sometimes used for curing malaria. This drug is also used to treat several intestinal infections and sexually transmitted infections. This medicine is not recommended for use in case of common cold, flu or viral infection since it is active against infections caused by bacteria only.

Symptoms of overdose include nausea, vomiting, diarrhea, prostration. Treatment is supportive and symptomatic. Take as directed. Take all of prescribed medication. Do not discontinue until prescription is completed.

Take suspension 1 hour before or 2 hours after meals; tablet form may be taken with meals to decrease GI effects. Do not take with aluminum- or magnesium-containing antacids. May cause transient abdominal distress, diarrhea, headache.

Report signs of additional infections (eg, sores in mouth or vagina, vaginal discharge, unresolved fever, severe vomiting, or diarrhea). Safety and efficacy of Azifast 2 % Gel have not been established in children <6 months of age with acute otitis media and in children <2 years of age with pharyngitis/tonsillitis.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Azifast 2 % Gel

    • Bronchitis

    • Sinusitis

    • Pharyngitis/Tonsillitis

    • Upper Respiratory Tract Infection

    • Lower Respiratory Tract Infection

    • Skin And Structure Infection

    • Bacterial Infections

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Azifast 2 % Gel ?

    • Hypersensitivity

    • Severe Liver Impairment

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Azifast 2 % Gel ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Azifast 2 % Gel

    • How long is the duration of effect?

      The effect of this drug lasts for an average duration of 2 to 4 days.

    • What is the onset of action?

      The effect of this drug can be observed within 2 to 3 hours of dose administration.

    • Are there any pregnancy warnings?

      This drug is not recommended for use by pregnant women unless extremely necessary. Consult your doctor to weigh the risks and benefits of taking it.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      This drug is not recommended for the breastfeeding mothers unless extremely necessary. Close monitoring of the infant will be required if taking it at all.

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Consult a doctor before taking the medicine when consuming alcohol.

    • Is it safe to drive while on this medicine?

      The side effects of this drug can be adverse and when facing the same, driving should be completely avoided.

    • Does this affect liver function?

      It should be avoided if the person is suffering from any type of liver disease.

    • Does this affect kidney function?

      Caution must be taken while taking this medication in patients with kidney disease. Adjustment of dose is required, thus consult your doctor before taking Azifast 2 % Gel.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Take the missed dose as soon as possible and avoid taking it if its almost time for the other dose.

    • Are there any overdose instructions?

      A doctor should be consulted immediately if such a situation is suspected.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Azifast 2 % Gel approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This medicine works by inhibiting protein synthesis by binding itself to 50S ribosomal subunits of the sensitive micro-organism. This infringes with transpeptidation and translocation and thus inhibits protein synthesis and cell growth.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Azifast 2 % Gel ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Monitoring should be done of liver function tests and CBC differential when the patient is on this medicine.
      • Interaction with Medicine

        • May inhibit CYP3A3/4 enzyme (mild).
        • Increased effect/toxicity: Azifast 2 % Gel may increase levels of tacrolimus, phenytoin, ergot alkaloids, alfentanil, astemizole, terfenadine, bromocriptine, carbamazepine, cyclosporine, digoxin, disopyramide, and triazolam; Azifast 2 % Gel did not affect the response to warfarin or theophylline although caution is advised when administered together.
        • Avoid use with pimozide due to significant risk of cardiotoxicity.
      • Interaction with Food

        Rate and extent of GI absorption decreased; take this medicine on an empty stomach.
      • Interaction with Disease

        • Qt Prolongation: Inform your doctor if you have an arrhythmia, any heart disease or drugs that prolong QT interval such as psychiatric drugs, anti-arrhythmic drugs.
        • Liver Disease: Inform your doctor if you have any liver disease and drugs that cause liver damage (Eg: TB drugs, HIV drugs).
        • Myasthenia Gravis: This medicine has certain interactions with diseases. A few of the diseases it interacts with are QT Prolongation, Liver disease and Myasthenia Gravis.
        • Use with caution in patients with hepatic dysfunction; hepatic impairment with or without jaundice has occurred chiefly in older children and adults.
        • It may be accompanied by malaise, nausea, vomiting, abdominal colic, and fever; discontinue use if these occur.
        • May mask or delay symptoms of incubating gonorrhea or syphilis, so appropriate culture and susceptibility tests should be performed prior to initiating Azifast 2 % Gel.
        • Pseudomembranous colitis has been reported with use of macrolide antibiotics.

      FAQs about Azifast 2 % Gel

      • Ques : What is Azifast 2 % Gel?

        Ans : It performs its action by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.

      • Ques : What are the uses of Azifast 2 % Gel?

        Ans : Azifast 2 % Gel is a salt, which is used for the treatment and prevention from conditions such as community-acquired pneumonia, pharyngitis/tonsillitis, and skin and soft tissue infections.

      • Ques : What are the Side Effects of Azifast 2 % Gel?

        Ans : Side effects include diarrhea, dry or scaly skin, abdominal pain, difficult or painful urination, vomiting, fever, acid or sour stomach, aggression or anger, excessive air or gas in the stomach, and heartburn.

      • Ques : What are the instructions for storage and disposal Azifast 2 % Gel?

        Ans : This drug should be kept in a cool dry place and its original packaging. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses.

      • Ques : Can the use of Azifast 2 % Gel cause diarrhea?

        Ans : Yes, the use of Azifast 2 % Gel can cause diarrhea. It is an antibiotic that kills harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, consult your doctor immediately.

      • Ques : Is Azifast 2 % Gel safe?

        Ans : This drug is safe if used at prescribed doses as advised by your doctor.

      • Ques : Is Azifast 2 % Gel an antibiotic?

        Ans : Yes, this medication is an antibiotic that belongs to a class of antibiotics known as macrolides.

      • Ques : What if I don't get better even after taking Azifast 2 % Gel?

        Ans : You should inform your doctor if you do not notice any improvement in your symptoms after 3 days of taking Azifast 2 % Gel and if your symptoms get worse.

      References

      • Azithromycin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 23 Nov 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/azithromycin

      • Azithromycin 250 Film-coated Tablets- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 23 Nov 2021]. Available from:

        https://www.medicines.org.uk/emc/product/11680/smpc

      • AZITHROMYCIN- azithromycin monohydrate tablet, film coated- Daily Med [Internet]. dailymed.nlm.nih.gov. 2008 [Cited 23 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a2b0c06b-e93d-f5aa-e053-2995a90ac9aa

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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