Lybrate Logo
Get the App
For Doctors
Login/Sign-up
tab_logos
About
tab_logos
Feed
Overview

Harflox 400 MG Tablet

Manufacturer :  Taurus Laboratories Pvt Ltd
Medicine Composition :  Norfloxacin
Prescription vs OTC : Prescription by Doctor required

About Harflox 400 MG Tablet

Harflox 400 MG Tablet is a used to treat uncomplicated urinary tract infections and cystitis caused by susceptible gram-negative and gram-positive bacteria. It is also prescribed to treat sexually transmitted disease (eg, uncomplicated urethral and cervical gonorrhoea) caused by N. gonorrhoeae.

This medicine is also used to treat prostatitis due to E. coli; ophthalmic solution for conjunctivitis. Harflox 400 MG Tablet is not recommended in children <18 years of age. CNS stimulation may occur which may lead to tremor, restlessness, confusion, and very rarely to hallucinations or convulsive seizures.

However, remember that this drug will not be effective for infections that aren’t caused by bacteria (viral infections such as common cold and the flu). Using an antibiotic repetitively and for infections that aren’t bacterial will lead the medicine to lose its potency over a period of time.

The treatment plan and dosage will depend upon the severity of the condition. It is advised to take this drug minimum two hours prior to consuming other minerals/vitamins or such products containing aluminium/magnesium such as antacids.

For best results, take this medicine at regular intervals every day. Try to limit your intake of caffeinated beverages such as coffee or tea, for that matter, as caffeine can interfere with the medicine’s potency in all probability. Don’t consume any dairy product either two hours prior to or an hour after taking this medication.

Risk factors for this medicine include kidney disorders, heart afflictions and epileptic seizures. It isn’t recommended for children below the age of 12 years. Overdosing on this medicine can result in irregular (slow) heartbeats.

Few side effects include an allergic response in the form of rashes, irritation of the skin, itching, etc. (though very rare), chest pain, dizziness, confusion, seizures, liver damage, joint or muscle pain, a ringing sensation in the ears (tinnitus), lightheadedness, diarrhea, fatigue, nausea, headaches and troubled sleeping.

Don’t take narcotic pain medicines if you experience any of these side effects since these can cause you more harm than good. Yeast infection and oral thrush are other concerns that might show up if you use this medicine indiscriminately. Know from your doctor the names of all those drugs that could diminish the efficacy of this medication.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Harflox 400 MG Tablet

    • Bacterial Infections

    • Cystitis

    • Prostatitis

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Harflox 400 MG Tablet ?

    • Allergy

      Avoid taking Harflox 400 MG Tablet if you have a known allergy to this medicine or any other medicines belonging to the class fluoroquinolones.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Harflox 400 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Harflox 400 MG Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 9 to 12 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 1 to 2 hours.

    • Are there any pregnancy warnings?

      This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      Use of this medicine is not recommended in women who breastfeed due to the adverse effect on the development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

    • Is It safe with alcohol?

      It is unsafe to consume alcohol along with this medicine.

    • Is it safe to drive while on this medicine?

      It is not known whether Harflox 400 MG Tablet affects the patients ability to drive or not.

    • Does this affect kidney function?

      Caution must be taken in patients with kidney disease. Adjustment of dose is needed. Kindly consult your doctor before taking it.

    • Does this affect liver function?

      Limited information is available regarding the use of this medicine in patients with liver disease. Kindly consult your doctor before doing it.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the substitutes for Harflox 400 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Harflox 400 MG Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Harflox 400 MG Tablet approved?

    • India

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This medicine works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Harflox 400 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Information not available.
      • Interaction with Medicine

        Disulfiram

        Increased toxicity/serum levels: Quinolones cause increased levels or toxicity of digoxin, caffeine, warfarin, cyclosporine, and possibly theophylline. Cimetidine and probenecid increase quinolone levels.
      • Interaction with Disease

        Central Nervous System Depression

        If you suffer from CNS disorder and you take Harflox 400 MG Tablet, then you may experience tremors, restlessness, anxiety, confusion and hallucinations. Avoid consuming caffeine-containing products like coffee, chocolates and energy drinks.

        Qt Prolongation

        Avoid using Harflox 400 MG Tablet if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.

        Colitis

        Avoid taking Harflox 400 MG Tablet if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.
      • Interaction with Food

        Dairy products

        The desired effect of Harflox 400 MG Tablet is not observed if consumed with dairy products. There should be at least 2 hours gap between taking Harflox 400 MG Tablet and dairy products.

        Decreases absorption with food; should be administered on an empty stomach with water

      FAQs about Harflox 400 MG Tablet

      • Ques : What is Harflox 400 MG Tablet?

        Ans : This medication belongs to the class of fluoroquinolones and used to treat Bacterial infections.

      • Ques : How long do I need to use Harflox 400 MG Tablet before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Harflox 400 MG Tablet?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Harflox 400 MG Tablet empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Harflox 400 MG Tablet?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Ofloxacin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 31 May 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ofloxacin

      • Ofloxacin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 31 May 2022].Available from:

        https://go.drugbank.com/drugs/DB01165

      • OFLOXACIN Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 31 May 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=OFLOXACIN

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
      swan-banner
      Sponsored

      Popular Questions & Answers

      View All

      I want to eradicate klebsiella oxytoca from pro...

      related_content_doctor

      Dr. K V Anand

      Psychologist

      This type of prostate enlargement isn't thought to be a precursor to prostate cancer. With this c...

      I am suffering from loose motion .Can I take no...

      related_content_doctor

      Dr. Prashant K Vaidya

      Homeopath

      dietary changes to avoid foods triggering loose stools. consuming foods high in fiber. taking ant...

      Is norfloxacin 400, advisable gas, bloating, an...

      related_content_doctor

      Dr. Nash Kamdin

      General Physician

      Dear lybrateuser, - Better to avoid norfloxacin if you have bloating & gas formation as it can in...

      Ketoconazole cream will work on anal fissure an...

      related_content_doctor

      Dr. Sreepada Kameswara Rao

      Homeopathy Doctor

      Your anal fissures.Take easily digestible foods with fibre-including , vegetables, curds and frui...

      Can I take Norfloxacin 400 mg for burning sensa...

      related_content_doctor

      Dr. Dhaval Thakkar

      General Surgeon

      Hello lybrate-user First of all, as you may know Norfloxacin is an antibiotic and it should not b...

      Table of content

      Content Details
      Profile Image
      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
      Profile Image
      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
      chat_icon

      Ask a free question

      Get FREE multiple opinions from Doctors

      posted anonymously
      swan-banner