Norfloxacin is a combination medicine that is used to cure bacterial infections. It is primarily used to treat diarrhoea and dysentery. It is a combination of two antibiotics Norfloxacin and Tinidazole.
However, remember that this drug will not be effective for infections that aren’t caused by bacteria (viral infections such as common cold and the flu). Using an antibiotic repetitively and for infections that aren’t bacterial will lead the medicine to lose its potency over a period of time.
The treatment plan and dosage will depend upon the severity of the condition. It is advised to take this drug minimum two hours prior to consuming other minerals/vitamins or such products containing aluminium/magnesium such as antacids.
For best results, take this medicine at regular intervals every day. Try to limit your intake of caffeinated beverages such as coffee or tea, for that matter, as caffeine can interfere with the medicine’s potency in all probability. Don’t consume any dairy product either two hours prior to or an hour after taking this medication.
Risk factors for this medicine include kidney disorders, heart afflictions and epileptic seizures. It isn’t recommended for children below the age of 12 years. Overdosing on this medicine can result in irregular (slow) heartbeats.
Few side effects include an allergic response in the form of rashes, irritation of the skin, itching, etc. (though very rare), chest pain, dizziness, confusion, seizures, liver damage, joint or muscle pain, a ringing sensation in the ears (tinnitus), lightheadedness, diarrhea, fatigue, nausea, headaches and troubled sleeping.
Don’t take narcotic pain medicines if you experience any of these side effects since these can cause you more harm than good. Yeast infection and oral thrush are other concerns that might show up if you use this medicine indiscriminately. Know from your doctor the names of all those drugs that could diminish the efficacy of this medication.
The medicine is useful against the following conditions:
Tendinitis Or Tendon RuptureAvoid taking this medicine if you have a past history of tendinitis or tendon rupture after using Norfloxacin.
- fatigue of muscles under voluntary control).
How long is the duration of effect?The effect of this medicine lasts for an average duration of 9 to 12 hours.
What is the onset of action?The peak effect of this medicine can be observed in 1 to 2 hours.
Are there any pregnancy warnings?This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.
Is it habit forming?No habit forming tendency has been reported.
Are there any breast-feeding warnings?Use of this medicine is not recommended in women who breastfeed due to the adverse effect on the development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Monitoring of undesired effects like diarrhea, diaper rash is necessary.
Are there any missed dose instructions?The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
Are there any overdose instructions?Seek emergency medical treatment or contact the doctor in case of overdose.
Below is the list of medicines, which contains Norfloxacin as ingredient
This medicine is a combination of Norfloxacin and Tinidazole. These drugs are antibiotic and belong to fluoroquinolone and anthelmintics, respectively. Thus it works following a dual mechanism.
Firstly, it works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.
Secondly, it enters into the organism and forms the free radical. A concentration gradient is created in the organism due to alteration in the molecule and promotes the influx of the molecule. Thus, the free radical and the altered molecule will interfere with the DNA synthesis and stops the growth of the organism.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Disease
Central Nervous System DepressionIf you suffer from CNS disorder and you take Norfloxacin, then you may experience tremors, restlessness, anxiety, confusion and hallucinations. Avoid consuming caffeine-containing products like coffee, chocolates and energy drinks.
Qt ProlongationAvoid using Norfloxacin if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.
ColitisAvoid taking Norfloxacin if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.
Interaction with Alcohol
AlcoholInteraction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
LabInformation not available.
Interaction with Food
Dairy productsThe desired effect of Norfloxacin is not observed if consumed with dairy products. There should be at least 2 hours gap between taking Norfloxacin and dairy products.
Interaction with Medicine
EscitalopramYou may experience dizziness, lightheadedness, shortness of breath, or heart palpitations if these medicines are used together. This interaction is more likely to happen if you suffer from any heart disease (Arrhythmia) or have a family history of Arrhythmia. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.
Ethinyl EstradiolThe desired effect of contraceptive pills will not be achieved if these medicines are used together. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.
CorticosteroidsYou may experience pain, swelling, or inflammation in ankle, shoulder, hand, or thumb if these medicines are used together. This interaction is more likely to occur in elderly population who have undergone a kidney or heart transplantation. Replacement of the medicine should be made under the doctor's supervision.
AspirinYou may experience tremors, involuntary muscle movements, hallucinations, or seizures if these medicines are used together. This interaction is more likely to happen if you have a history of seizures or family history of seizures. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.
Antidiabetic drugsYou may experience hypoglycemic effects like dizziness, headache, nervousness, confusion, tremor and weakness if these medicines are used together. Hyperglycemic effects like increased thirst, urination and hunger are less likely to occur. Regular blood glucose checkups are to be performed if you are diabetic or if you are suffering from any kidney disease. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.
WarfarinTinidazole may increase the concentration of warfarin and increase the risk of bleeding. Inform the doctor if you have any bleeding disorder. Any symptoms of unusual bleeding, blood in stools, headache, and dizziness should be reported to the doctor. An alternate class of medicine should be considered based on the clinical condition.
DisulfiramTinidazole is not recommended in patients receiving disulfiram due to the risk of confusion and psychotic symptoms. Inform the doctor if you are receiving these medications. Any symptoms of change in behavior, irritation, and altered coordination should be reported to the doctor.
Ques: What is Norfloxacin?
Ques: How long do I need to use Norfloxacin before I see improvement in my condition?
Ques: At what frequency do I need to use Norfloxacin?
Ques: Should I use Norfloxacin empty stomach, before food or after food?
Ques: What are the instructions for the storage and disposal of Norfloxacin?
Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.