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Last Updated: Jan 10, 2023

Nephrotic Syndrome - 9 Surprising Causes Behind it

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Dr. Ravi BansalNephrologist • 28 Years Exp.DM - Nephrology, MD-Medicine, MBBS
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Nephrotic syndrome is a type of kidney disorder wherein, the body passes out excess amount of proteins through urine, owing to the damage caused to the tiny clusters of blood vessels in the kidneys. The symptoms include putting on excessive weight as a result of fluid retention, foamy urine and severe swelling around the region of the feet, ankles and eyes.

Common causes behind it

  1. Minimal change disease (also known as nil disease) leads to the abnormal functioning of the kidneys
  2. Excess deposit of amyloid proteins in the organs, thus taking a toll on the filter mechanism of the kidneys.
  3. Diabetes affecting the glomeruli (capillaries present in the nephrons of the kidneys).
  4. Systemic lupus  erythematous causing chronic swelling of your kidney.
  5. Membranous nephropathy wherein the membranes in your glomeruli thicken.
  6. Infections such as malaria, hepatitis C, hepatitis B and HIV.
  7. Medications to combat infections and nonsteroidal anti-inflammatory drugs.

Treatment Available

  1. Kidney Biopsy is an essential part of disease assessment.
  2. Angiotensin-converting enzyme inhibitors bring down blood pressure levels as well as the amount of protein discharged from the urine.
  3. Water pills help control sweating, thus, increasing the fluid flushed from the kidneys.
  4. Statins reduce cholesterol levels.
  5. Blood thinners such as anticoagulants lower the risk of blood clots.
  6. Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
  7. Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling. If you wish to discuss about any specific problem, you can consult a doctor and ask a free question.

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