My brother, who is 14 years old, is suffering from frequent urination during the nights. He is fit otherwise. We got him diagnosed, but nothing showed up in the report too. He is a bit obese but is physically fit otherwise. Please check into this issue and let me know what you can do about it. We consulted several doctors but all in vain. Please help me with this issue.

Dr. Souvik PaulGeneral Physician3yrs exp

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Increased frquency in urine or polyuria may be due to many causes. If his blood sugar levels are normal, diabetes mellitus is excluded. First water and sugar intake needs to be decreased. If problem does not subside after that, 24 hr urine volume measurement need to be done. If its more than 3litrs, then urine and serum osmolality and specific gravity needs to be evaluated. Depending on them serum vasopressin level and1 desmopressin stimulation test needs to be done later. These tests will exclude central or peripheral diabetes insipidus or polydipsia. Treatments can be done accordingly. Also history of taking any drugs like lithium, demeclocycline, amphotericin b, aminoglycosides etc. Or histry of any cns infections, trauma, surgeries needs to be excluded. 

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