I am 25 yr old i still have acne problem. I v been using Adacine (adapalene & clindamycin phosphate gel) since 5 yrs. If i stop using the gel for more than 3 days acne starts all over my face, throat, chest and back. Additionally i use SOTRET R (isotretinoin capsule usp 20 mg) and DIVAINE - 100 (Minocycline tablets BP 100 mg) tablets for 2 or 3 days when ever the acne problem increases even while using the gel. Is there any other better solution for my problem. I can not continue using these medicines for yrs. Please help me.