My father in law diagnosed of myleoprofilerative disorder (essential thrombocytosis. His age is 71 years. Med oncologist suggested Hydab 500 and Zyloric� 100 mg. Once count is normal stop the medicine. We are confused state. Please clarify our doubts. Cbc count Wbc 12k Platelets 14 lakhs Rbc normal range Blood Report: Jak 2 mutation is positive My question is First of all different between blood cancer Vs Myeloproliferarive Disorder? Is it curable by medication? Are there any surgery for permanent cure? Please suggest
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Dear Bala Ji, Thanks for your QUERRY. Myeloma proliferative disorder is also Sort of cancer occuring in bone marrow elements. There is increase no. Of platelets. In younger and suitable patients bone marrow transplantation can be done., Otherwise only to be controlled by drug. There is no surgery for this condition.
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Hi. First of all, essential thrombocythemia diagnosis requires bone marrow aspiration and biopsy test to confirm. If bone marrow study also confirms it as essential thrombocythenia, then hydroxyurea and aspirin, for life long is the treatnent of choice. Given the age of patient, he is high risk, so need these cytoreduction and antiplatelet therapy. The dose may need to be adjusted according the response and other complications. The disease entity is considered to be a chronic blood cancer amenable to medicine only and regular follow up, but the long term complications include leukemic transformation (developing blood cancer) and marrow fibrosis (drying up of marrow). Hope it will help you.
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