Prescription vs OTC: Prescription by Doctor required

Hydroxyurea is an oral medicene that is prescribed to patients suffering from chronic myelogenous leukemia, acute myelogenous leukemia, sickle-cell disease, ovarian cancer, cervical cancer, and polycythemia vera.

This medicine slows down the growth of cancer cells in the body and can reduce the need for blood tranfusion. It comes as a capsule that is usually taken once in a day. But talk to your doctor regarding the right dosage for you.

Do not use this medicine if- you are allergic to any of its ingredients; have a prescription for didanosine or stavudine; have severe bone marrow depressin; have anemia or count of white blood cells or platelets is low.

Also, let your healthcare provider know before prescription if- you are pregnant or are planning to become pregnant, are breastfeeding, have a history of allergies to food or medicine, have anemia, kidney or liver problems or if you are a HIV positive patient.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

Below are the conditions for which this medicine is used:

  • Hypersensitivity

  • Undiagnosed Anemia

  • Severe Liver Impairment

  • Kidney Impairment

  • Severe Myelosuppression

  • Nursing Mothers

  • Low Wbc Count

  • Thrombocytopenia

Common side effects of this medicine include:

  • Oligospermia (Low Sperm Count)

  • Azoospermia (Absence Of Sperms)

  • Headache

  • Dizziness

  • Bleeding

  • Skin Reaction

  • Chills

  • Alopecia

  • Abdominal Pain

  • Is It safe with alcohol?

    Interaction with alcohol is unknown. Please consult your doctor.
  • Are there any pregnancy warnings?

    This medicine is unsafe to use during pregnancy.
    There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
  • Are there any breast-feeding warnings?

    This medication is probably unsafe to use during breastfeeding. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    Should not drive or operate machinery unless it has been shown not to affect physical or mental ability.
  • Does this affect kidney function?

    Caution to be advised in patients with impaired renal function.
  • Does this affect liver function?

    There is no data available. Please consult doctor before consuming the drug.
  • What is the onset of action?

    The effect of the medicine is initiated within 2 hrs of its administration.
  • How long is the duration of effect?

    This medicine shows its action for about 8 hrs of its administration.
  • Are there any missed dose instructions?

    If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
  • Are there any overdose instructions?

    Consult you doctor in case of overdosing.

Below is the list of medicines, which contains Hydroxyurea as ingredient

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This medication belongs to the class of an antineoplastic agent. It gets converted to a free radical and inhibits the entire DNA replicate complex, including ribonucleotide reductase and selectively inhibits DNA synthesis, while also inhibiting DNA repair mechanisms. Hence it causes neoplastic cell death.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Medicine


    This mediation if taken along with zidovudine, zalcitabine, didanosine, fluorouracil, cytarabine and synergise the effect to be produced. Thus it may lead to toxicity. Hence concomitant use of these must be avoided.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Hydroxyurea
What are the uses of Hydroxyurea
What are the contraindications of Hydroxyurea ?
What are the side effects of Hydroxyurea ?
Key highlights of Hydroxyurea
What are the dosage instructions?
Medicines containing Hydroxyurea
How does this medication work?
What are the interactions of Hydroxyurea ?