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Overview

Perinorm 10Mg Tablet

Manufacturer :  Ipca Laboratories Ltd
Medicine Composition :  Metoclopramide
Prescription vs OTC : Prescription by Doctor not required

About Perinorm 10Mg Tablet

Perinorm 10Mg Tablet is primarily used for symptomatic treatment of diabetic gastric stasis, gastroesophageal reflux; prevention of nausea associated with chemotherapy or postsurgery and facilitates intubation of the small intestine.

Perinorm 10Mg Tablet is used in the treatment of diabetes, stomach and intestinal diseases. It increases the muscle contractions of the upper digestive tract. It provides relief in cases of heartburn and migraines. It prevents feelings of nausea and the tendency to vomit. Perinorm 10Mg Tablet falls under the category of drugs known as dopamine-receptor antagonists.

The associated side-effects that come with the use of Perinorm 10Mg Tablet are headache, dizziness, sleeping troubles, drowsiness and restlessness. Major side effects include depression, uncontrollable body movements, high fever, shakiness, skin rash, hives, rapid and irregular heartbeat and stiff muscles.

Avoid using Perinorm 10Mg Tablet if; you have any allergies, you have bleeding or blockage in your intestines or stomach, you have epilepsy, seizure, kidney, liver or Parkinson’s diseases, you have high blood pressure, breast cancer or a history of depression.

Ideally the dosage for you will be prescribed by the doctor taking into consideration your specifications. Perinorm 10Mg Tablet is available in both tablet and solution form. Usually the dosage prescribed is four times a day which needs to be taken before each meal and at night before sleeping.

Take this drug as prescribed, 30 minutes prior to eating. Do not increase dosage. Do not use alcohol or other CNS depressant or sleeping aids without consulting prescriber. May cause dizziness, drowsiness, or blurred vision.

Use caution when driving or engaging in tasks that require alertness until response to drug is known. May cause restlessness, anxiety, depression, or insomnia (will reverse when medication is discontinued). Report any CNS changes, involuntary movements, unresolved diarrhea. If diabetic, monitor serum glucose regularly.

Symptoms of overdose include drowsiness, ataxia, extrapyramidal reactions, seizures, methemoglobinemia (in infants); disorientation, muscle hypertonia, irritability, and agitation are common.

Perinorm 10Mg Tablet often causes extrapyramidal symptoms (eg, dystonic reactions) requiring management with diphenhydramine 1-2 mg/kg (adults) up to a maximum of 50 mg I.M. or I.V. slow push followed by a maintenance dose for 48-72 hours. When these reactions are unresponsive to diphenhydramine, benztropine mesylate I.V. 1-2 mg (adults) may be effective. These agents are generally effective within 2-5 minutes.

    What are the uses of Perinorm 10Mg Tablet

    What are the contraindications of Perinorm 10Mg Tablet ?

    What are the side effects of Perinorm 10Mg Tablet ?

    Key highlights of Perinorm 10Mg Tablet

    • Is It safe with alcohol?

      Use of this medicine with alcohol may cause excessive drowsiness and calmness with alcohol.

    • Are there any pregnancy warnings?

      Pregnant women must consult doctor before using this medication.

    • Are there any breast-feeding warnings?

      This medicine unsafe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      Caution is advised when driving or operating machinery.

    • Does this affect kidney function?

      Caution to be advised in patients with impaired renal function.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    • What is the onset of action?

      The effect of this drug will be initiated within 30 - 1 hour after its administration.

    • How long is the duration of effect?

      The effect of this drug remain effective for about 1 - 2 hours, regardless of the route of administration.

    What are the substitutes for Perinorm 10Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Perinorm 10Mg Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

    • Are there any overdose instructions?

      In case of overdose, consult your doctor.

    How does this medication work?

    This medication is an antiemetic that works by inhibiting gastric smooth muscle relaxation caused by dopamine. This improves the response of the gastrointestinal smooth muscles to cholinergic stimulation, which leads to an increase of gastric emptying into the intestines. It antagonises the dopamine D2 receptors in the medulla which prevents nausea and vomiting.

      What are the interactions of Perinorm 10Mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Additive CNS effect, avoid use.
      • Interaction with Lab Test

        This drug might affect the results of aminotransferase [ALT (SGPT)/AST (SGOT)] (S), and amylase (S) if patient undergoes pathological test while taking this medicine.
      • Interaction with Medicine

        • This medication interacts with Phenytoin, Atropine, Chlorpromazine and others.
        • Increased toxicity: Opiate analgesics may increase CNS depression.
      • Interaction with Disease

        Use with caution in patients with Parkinson's disease and in patients with a history of mental illness; dosage and/or frequency of administration should be modified in response to degree of renal impairment; extrapyramidal reactions, depression; may exacerbate seizures in seizure patients; to prevent extrapyramidal reactions, patients may be pretreated with diphenhydramine; elderly are more likely to develop dystonic reactions than younger adults; use lowest recommended doses initially.

      FAQs about Perinorm 10Mg Tablet

      • Ques : What is Perinorm 10Mg Tablet?

        Ans : Perinorm has Metoclopramide as an active element present in it. This medicine performs its action by controlling vomiting sensations and speeds up emptying of stomach.

      • Ques : What are the uses of Perinorm 10Mg Tablet?

        Ans : Perinorm is used for the treatment and prevention from conditions such as Chemotherapy induced nausea and vomiting and Gastroparesis.

      • Ques : What are the Side Effects of Perinorm 10Mg Tablet?

        Ans : Side effects include Dizziness, Abdominal pain, Convulsions, Headache, Skin rash, Irregular heartbeat, Diarrhea, Restlessness, Breast pain and tenderness, and Increased flow of breast milk.

      • Ques : What are the instructions for storage and disposal Perinorm 10Mg Tablet?

        Ans : Perinorm should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets.

      • Ques : How long do I need to use Perinorm 10Mg Tablet before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Perinorm 10Mg Tablet?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Perinorm 10Mg Tablet empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Perinorm 10Mg Tablet?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : How is this Perinorm 10Mg Tablet administered?

        Ans : This medication is administered orally.

      References

      • Metoclopramide- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 3 December 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/364-62-5

      • METOCLOPRAMIDE tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2021 [Cited 24 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2ad82e21-44b6-4a2f-a62f-05ca37347ea5

      • Maxolon Tablets 10mg- EMC [Internet]. www.medicines.org.uk. 2019 [Cited 24 Nov 2021]. Available from:

        https://www.medicines.org.uk/emc/product/6213/smpc

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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