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Ondem 4 MG Tablet MD

Manufacturer: Alkem Laboratories Ltd
Medicine composition: Ondansetron
Prescription vs.OTC: Prescription by Doctor not required
Last Updated: August 02, 2019

Developed by Alkem Laboratories Ltd, Ondem 4 MG tablet comprises of Ondansetron which belongs to a group called antiemetics and it is a major drug which is used for the treatment of nausea and vomiting which are a result of chemotherapy, surgery, and radiation. It blocks serotonin from getting released in the gut and central nervous system of the patient and also helps in prevention of nausea and vomiting.

The medicine can be consumed with food or without food. For patients that undergo chemotherapy, the medicine must be consumed orally about half an hour before the therapy begins. If the patient is getting a radiation treatment, then it is advisable to take the medicine 1-2 hours before the treatment begins.

Before a surgery, the medicine must be consumed one hour before the surgery commences in order to prevent nausea. The 5-HT3 receptors are blocked peripherally on the vagal nerve terminals and they are blocked centrally when it comes to the chemoreceptor trigger zone by this medicine.

This medicine is useful against the following conditions:

  • Hypersensitivity

This medicine causes side effects such as:

  • How long is the duration of effect?

    The effect of Ondem 4 MG Tablet MD lasts for about 12 to 28 hours since the medicine is predominantly excreted through urine.

  • What is the onset of action?

    Within 2 hours after consumption, the peak effects of the medicine are observed. The intravenous form of the medicine shows peak effects within 30 minutes.

  • Are there any pregnancy warnings?

    Ondem 4 MG Tablet MD must not be consumed by pregnant women. A doctor must be consulted for more details.

  • Is it habit forming?

    Ondem 4 MG Tablet MD tablet doesn’t have any habit forming tendencies.

  • Are there any breast-feeding warnings?

    Ondem 4 MG Tablet MD must not be used by breastfeeding women since there is no absolute data that talks about excretion through human breast milk.

  • Is It safe with alcohol?

    Alcohol and its effects with the medicine have not been clinically acquired yet. The doctor must be consulted before consuming alcohol during the treatment.

  • Is it safe to drive while on this medicine?

    Ondem can cause drowsiness in the patient, which can be very dangerous while driving. The patient must refrain from performing any activity that requires alertness in the patient.

  • Does this affect kidney function?

    For patients suffering from any kidney abnormalities, the consumption of Ondem can cause kidney disorders such as kidney failure. Consulting the doctor before consumption is a prudent idea.

  • Does this affect liver function?

    Patients that have a history of liver damage must not consume the medicine as it can cause a high increase in the level of liver enzymes.

Below is the list of medicines, which have the same composition, strength and form as Ondem 4 MG Tablet MD , and hence can be used as its substitute.

  • Are there any overdose instructions?

    If the patient overdoses, the doctor must be consulted immediately and medical attention must be provided as soon as possible.

  • Are there any missed dose instructions?

    For Ondem 4 MG, the patient must take the missed dose as soon as possible and skip the dose if the time for the next dose as scheduled occurs. Doubling the dose is not advisable.

Ondem 4 MG Tablet MD works by blocking 5-HT3 receptors peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Disease

    Ondem interacts strongly with heart diseases or arrhythmia with drugs that cause QT prolongation (Arrhythmia and antipsychotics) and should be reported as soon as possible to the doctor. People who have been suffering from liver disease must refrain from consuming the medicine due to reactions with drugs that affect the liver and diseases such as jaundice and hepatitis which affect the liver adversely.

  • Interaction with Medicine

    Ondem 4 MG Tablet MD reacts severely with medicines that contain Amiodarone, Apomorphine, and Amitriptyline compounds. It has moderate reactions with Cyclophosphamide, Carbamazepine, and Phenytoin compounds.

Ques: What is Ondem 4 mg tablet md?

Ans: Ondem 4 mg tablet MD is a medication which contains Ondansetron as an active ingredients in it. It performs its actions by restricting the action of a serotonin (chemical messenger ) in the brain that may cause nausea and vomiting during anti-cancer treatment known as chemotherapy or after surgery.

Ques: What is Ondem 4 mg tablet mg used for?


Ondem 4 mg tablet MD is a medication that is used to treat, control, and prevent the Below mentioned conditions, which are as follows:

  1. Nausea and vomiting
  2. Chemotherapy induced nausea and vomiting
  3. Post-operative nausea and vomiting

Ques: What are the side effects of Ondem 4 mg tablet md?


Ondem 4 mg tablet MD is a medication which has some known side effects. These side effects may or may not appear always and some of them are rare but severe. It is a prescribed medication, consult your doctor before taking it. If you experience any of the below mentioned side effects, contact your doctor immediately.

Here are some side effects of Ondem 4 mg tablet MD:

  1. Abnormal heartbeat
  2. Anxiety or agitation
  3. Chest pain (angina)
  4. Cold sensation
  5. Dizziness
  6. Flushing
  7. Headache
  8. Inability to urinate
  9. Intravenous injection site reaction
  10. Local burning sensation
  11. Palpitations
  12. Constipation
  13. Diarrhea
  14. Difficult urination
  15. Extra heartbeat
  16. Fever
  17. Feeling of discomfort

Ques: Can ondansetron make you sleepy?

Ans: Ondansetron which is an active ingredient of Ondem 4 mg tablet MD. It may cause sleepiness/dizziness. If you are observing such conditions, please consult your doctor.

Ques: How long do I need to use ondem 4 mg tablet md before I see improvement of my conditions?

Ans: This medication should be consumed, till the complete eradication of disease. Thus it is advised to use, till the time directed by your doctor and moreover taking this medication longer than it was prescribed, can also cause inadequate effect on the patient. So please consult your doctor.

Ques: At what frequency do I need to use ondem 4 mg tablet md ?

Ans: This medication is generally used once or twice a day, as the time interval upto which this medication has an impact, is around 12 to 28 hours, but it is not the standard frequency for using this medication. It is advised to consult your doctor for the dosage, as the frequency also depends on the patient's condition.

Ques: Should I use ondem 4 mg tablet md empty stomach, before food or after food?

Ans: This medication is commonly taken orally from mouth and the action of salts involved in this medication, do not depend on using it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a the day.

Ques: What are the instructions for storage and disposal of ondem 4 mg tablet md?

Ans: this medication contains salts, which are suitable to store at room temperature and keeping this medication above or below that, can cause inadequate effect. Protect it from moisture and light. Keep this medication away, from the reach of children. It is advised to dispose the expired or unused medication, for avoiding its inadequate effect.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MD-Pharmacology, MBBS
Table of Content
About Ondem 4 MG Tablet MD
What are the uses of Ondem 4 MG Tablet MD
What are the contraindications of Ondem 4 MG Tablet MD ?
What are the side effects of Ondem 4 MG Tablet MD ?
Key highlights of Ondem 4 MG Tablet MD
What are the substitutes for Ondem 4 MG Tablet MD ?
What are the dosage instructions?
How does this medication work?
What are the interactions of Ondem 4 MG Tablet MD ?
FAQs about Ondem 4 MG Tablet MD