Gliclazide
About Gliclazide
Gliclazide falls in the category of oral hypoglycemic. This medication is used in the treatment of type 2 diabetes. Gliclazide helps to control the blod sugar levels in the body. It activates the pancreas to secrete more insulin and also supports the body in utilizing insulin more effectively.
Gliclazide is used when other methods of treatment such as diet, weight loss and exercise have failed to produce the desired results. The dosage of Gliclazide varies from 80 mg to 320 mg on a daily basis. If one is to take a dose more than 160 mg then the dose is divided into two equal parts. It is recommended to avoid modifying the dose without consulting the doctor. Also, in case you miss a dose, avoid taking two doses in order to compensate for the missed dose.
It is advised not to take this medication if you – are allergic to any of its ingredients; are breast feeding or pregnant; have an infection; affected by type 1 diabetes; have kidney or liver problems; have undergone surgery.
Gliclazide also has some side effects that are not experienced by everyone taking it. The side effects are – diarrhea, dizziness, stomach cramps, joint pain, gastrointestinal problems, headaches, increased skin sensitivity, vomiting and nausea. Consult a doctor if you experience these side effects. It is advisable to stop from consuming this medication any further if you experience the following – seizures, chest pain, unconsciousness and severe skin reactions such as peeling and blistering.
Do inform you doctor about other medications you are taking before starting a course of Gliclazide. Gliclazide also causes reactions like warmth, nausea and flushing if one consumes alcohol. It is also recommended to follow a proper diet alongside the medication.
type diabetesInformation given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.
What are the uses of Gliclazide
Type 2 Diabetes Mellitus
Gliclazide is used in the treatment of Type II Diabetes Mellitus which is a condition with elevated blood glucose levels in the body.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.
What are the contraindications of Gliclazide ?
Avoid taking this medicine if you have a known allergy to Gliclazide or any other medicine belonging to the class sulphonylureas.
Diabetic Ketoacidosis
Avoid taking this medicine if you have repeated episodes of diabetic ketoacidosis.
Impaired Kidney Function
Avoid taking this medicine in patients with impaired kidney function or history of severe kidney injury.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.
What are the side effects of Gliclazide ?
Nausea Or Vomiting
Confusion
Weakness
Changes In Vision
Decreased Heartbeat
Elevated Liver Enzymes
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.
Key highlights of Gliclazide
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 24 hours.
What is the onset of action?
The peak effect of this medicine can be observed within 4-6 hours.
Are there any pregnancy warnings?
This medicine is not recommended for pregnant women.
Is it habit forming?
No habit forming tendencies were reported
Are there any breast-feeding warnings?
This medicine is not recommended for women who are breastfeeding.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.
What are the dosage instructions?
Missed Dose instructions
The missed dose can be taken as soon as you remember. If it is time for the next dosage then the missed dose can be skipped.
Are there any overdose instructions?
It is recommended to discontinue the medicine and contact your doctor immediately if an overdose is suspected. Symptoms like dizziness, confusion, increased heartbeat, tremor and sweating after taking the medicine should be reported immediately.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.
Where is the Gliclazide approved?
India
Japan
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.
Medicines containing Gliclazide
Below is the list of medicines, which contains Gliclazide as ingredient
- Glykind 80 MG Tablet
Mankind Pharmaceuticals Ltd
- Gliza 80 MG Tablet
Stadmed Pvt. Ltd
- Glizid Mr 30 MG Tablet MR
Panacea Biotec Ltd
- Glycinorm-M 40 Tablet
Ipca Laboratories Ltd
- Gliclaz M 80 Mg/500 Mg Tablet
Khandelwal Laboratories Pvt Ltd
- Glz Trio Tablet
Alembic Pharmaceuticals Ltd
- Glycinorm 80 MG Tablet MR
Ipca Laboratories Pvt Ltd.
- Glizid 80 MG Tablet
Panacea Biotec Ltd
- Glychek 80 MG Tablet
Indoco Remedies Ltd
- Glized 80 MG Tablet
Swiss Pharma Pvt. Ltd
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.
How does this medication work?
Gliclazide belongs to the class sulfonylureas. It works by lowering the blood glucose levels by stimulating the release of insulin from pancreatic beta cells.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.
What are the interactions of Gliclazide ?
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
- test
Interaction with Alcohol
Alcohol
Consumption of alcohol is not recommended when you are taking this medicine. Do not perform activities that require mental alertness like operating heavy machinery or driving a vehicle. Inform the doctor if you experience any undesired effect.Interaction with Lab Test
Lab
Information not available.Interaction with Medicine
Miconazole
This combination is not recommended as it leads to an increase in the concentration of Gliclazide. This may further cause hypoglycemic effects like dizziness, confusion and weakness. Inform the doctor if you are receiving these medicines. An alternate medicine should be considered based on the clinical condition.Phenylbutazone
This combination is not recommended as it leads to an increase in the concentration of Gliclazide, which may cause hypoglycemic effects like dizziness, confusion, weakness. Inform the doctor if you are receiving these medicines. An alternate medicine should be considered based on the clinical condition.Chlorpromazine
The desired effect of Gliclazide may not be achieved if taken with chlorpromazine. This interaction is more likely to occur if a high dose of chlorpromazine is used. Frequent monitoring of blood glucose levels is necessary. Dose adjustment or an alternative treatment should be considered based on the clinical condition.Glucocorticoids
The desired effect of Gliclazide may not be achieved if taken with glucocorticoids like prednisolone and methylprednisolone etc. This interaction is more likely to occur if glucocorticoids are taken for more than a week. Frequent monitoring of blood glucose levels and kidney function tests are necessary. Dose adjustment or an alternative treatment should be considered based on the clinical condition.Interaction with Disease
Hemolytic Anemia/G6Pd Deficiency
Gliclazide is not recommended for use in people suffering from Hemolytic Anemia. Reporting this condition to the doctor is a must. In such cases, alternate medication not belonging to Sulfonylureas should be considered.Heart Diseases
Gliclazide should be administered with extreme caution if you suffer from any disease of heart and blood vessels.Interaction with Food
Food
Information not available.
References
Gliclazide-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:
https://druginfo.nlm.nih.gov/drugportal/name/gliclazide
Gliclazide-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 1 June 2022].Available from:
https://go.drugbank.com/drugs/DB01120
Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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