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Overview

Famotidine 40 MG Tablet

Manufacturer: Cipla Ltd
Medicine composition: Famotidine
Prescription vs.OTC: Prescription by Doctor required

Famotidine 40 MG Tablet is a prescriptive drug that is used primarily in peptic ulcer diseases and other gastroesophageal reflux diseases. It is histamine h2 blocker that prevents acid production in the stomach. Famotidine 40 MG Tablet is sold under the trade name of Pepcid in the market. It comes in both liquid and tablet form and can also be injected into the body.

Aside from the ones already mentioned, the benefits of using Famotidine 40 MG Tablet are many; it aides in the treatment of heartburn, acid indigestion, of gastric and duodenal ulcers, and in the treatment of esophagitis. The associated side effects resulting from the taking of Famotidine 40 MG Tablet include dizziness, seizures, depression, sexual problems, headache, and shortness of breath, constipation and in certain cases diarrhea.

Inform your doctor or pharmacist if:

  • You are allergic to famotidine, cimetidine, nizatidine, ranitidine, or any other medications .
  • If you are taking any kind of prescriptive or non-prescriptive drugs, any kind of herbal medications or any kind of medications for heartburn.
  • You have a history of QT syndrome, asthma or any kind of breathing problems.
  • You are planning to become pregnant, are pregnant or are breastfeeding a baby.
  • You have phenylketonuria or any kind of kidney disease.

Famotidine should be taken in the amount as prescribed by your doctor depending on your condition. It is recommended that you measure the liquid with a cup or a syringe. Taking too much or too little may not show the desired results. If a proper diet is followed along with the intake of this medicine then your ulcer has a chance of healing within four weeks. Otherwise it may take up to eight weeks. Should you experience any chest pain then contact your doctor right away. Heartburn is often mistaken with the initial symptoms of a possible heart attack.

In case of a missed dose take it as soon as possible. However, if it is almost time for your next dose, then skip the previous one but do not take more medicine as overdosing may have adverse effects. If you do overdose then it is advised that you seek medical help immediately without delay.

Duodenal Ulcer
Famotidine 40 MG Tablet is used in the treatment of ulcers in the small intestine.
Gastric Ulcer
Famotidine 40 MG Tablet is used in the treatment of ulcers in the stomach.
Gastroesophagal Reflux Disease
Famotidine 40 MG Tablet is used for the treatment of a condition where the acid produced in the stomach causes irritation in the food pipe.
Hypersecretory Condition
Famotidine 40 MG Tablet is used to prevent and treat conditions where the amount of acid secreted in the stomach is abnormally high.
Not recommended in patients with known allergy to Famotidine 40 MG Tablet or other H2 antagonists.
In addition to its intended effect, Famotidine 40 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Diarrhea Major Rare
Itching Major Rare
Weakness Major Rare
Dizziness Major Rare
Black or tarry stools Major Rare
Fever Major Rare
Muscle or joint pain Major Rare
Constipation Minor Less Common
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 10 to 12 hours.
What is the onset of action?
The effect of this medicine can be observed in less than 1 hour after an oral dose and less than 30 minutes after an intravenous dose.
Are there any pregnancy warnings?
This medicine is recommended in pregnant women only if benefits overweigh the risks.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
This medicine is known to excreted through the breastmilk. It is recommended for breastfeeding women.
Below is the list of medicines, which have the same composition, strength and form as Famotidine 40 MG Tablet, and hence can be used as its substitute.
Alkem Laboratories Ltd
Cadila Pharmaceuticals Ltd
Cadila Pharmaceuticals Ltd
Zydus Cadila
Torrent Pharmaceuticals Ltd
Missed Dose instructions
Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of an overdose.
India
United States
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Gastro-intestinal bleeding Major
Use of Famotidine 40 MG Tablet is not recommended for use if any symptoms indicating gastrointestinal bleeding exists. Consult your doctor if there is blood in vomit or the stools are bloody or black.
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Glipizide Moderate
Famotidine 40 MG Tablet may increase the effect of antidiabetics medicines like glipizide, glimepiride which may lower the blood glucose levels. Monitoring of blood glucose levels is necessary. Any symptoms like dizziness, tiredness, weakness should be reported to the doctor. Dose adjustments or an alternate medicine should be considered based on the clinical condition.
Ketoconazole Moderate
Famotidine 40 MG Tablet will decrease the effect of antifungals, therefore inform the doctor if you are receiving any antifungals or gastric medications. Immediate medical treatment should be initiated if any symptoms of an increase in the severity of fungal infection appear. An alternate medicine should be considered based on the clinical condition.
Atazanavir Major
Report the use of either of the medicine to the doctor. Your doctor may adjust the dosage of Atazanavir when it is to be consumed along with Famotidine 40 MG Tablet. Do not stop the usage of any medication without consulting your doctor.
What are you using Famotidine 40 MG Tablet for?
Gastroesophagal Reflux Disease
Duodenal Ulcer
Gastric Ulcer
Other
How much was the improvement?
Average
Poor
How long did it take before seeing improvement?
More than 2 days
How frequently did you take this medicine?
Once a day
How did you take this medicine?
Empty stomach
What were the side effects of this medicine?
Weakness
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I am 45 year old lady having back ache very much. Sometimes sudden shocks in upper left back Shortness of breathe also Taking telma 20 and topcid 40 for long please tell.

Erasmus Mundus Master in Adapted Physical Activity, MPT, BPTh/BPT
Physiotherapist, Chennai
I am 45 year old lady having back ache very much.
Sometimes sudden shocks in upper left back Shortness of breathe als...
This is a general low back ache and for this you can follow these measures: one keep a pillow right under the knee while sleeping, next is you can keep ice in the painful area for about 5--10 minutes, if pain still persists you can stretch your body by twisting the waist on both sides how we used to do in the school drill similarly you can try which will help you relax as well will reduce the pain. It looks like you are anaemic. If you have back pain after you sit for long hours then it is due to your haemoglobin levels as it is important to check that. Anaemia always leads to the symptoms of being tired and also having back / leg pain though there may not be any pathological reasons for back pain. If you have leg pain then you have to rule out the casues for having leg pain. First of all check your weight and your haemoglobin levels, as Anaemia always leads to the symptoms of being tired and also having leg pain though there are no issues with the knee joint or back pain. If not if the pain radiates down the back of thigh and legs then it might be due to sciatica. Kindly consult the nearby physiotherapist. Hope you recover soon from the leg pain. •Standing hamstring stretch: Place the heel of your injured leg on a stool about 15 inches high. Keep your knee straight. Lean forward, bending at the hips until you feel a mild stretch in the back of your thigh. Make sure you do not roll your shoulders and bend at the waist when doing this or you will stretch your lower back instead of your leg. Hold the stretch for 15 to 30 seconds. Repeat 3 times. •Cat and camel: Get down on your hands and knees. Let your stomach sag, allowing your back to curve downward. Hold this position for 5 seconds. Then arch your back and hold for 5 seconds. Do 3 sets of 10. •Quadruped arm/leg raise: Get down on your hands and knees. Tighten your abdominal muscles to stiffen your spine. While keeping your abdominals tight, raise one arm and the opposite leg away from you. Hold this position for 5 seconds. Lower your arm and leg slowly and alternate sides. Do this 10 times on each side. •Pelvic tilt: Lie on your back with your knees bent and your feet flat on the floor. Tighten your abdominal muscles and push your lower back into the floor. Hold this position for 5 seconds, then relax. Do 3 sets of 10. •Partial curl: Lie on your back with your knees bent and your feet flat on the floor. Tighten your stomach muscles. Tuck your chin to your chest. With your hands stretched out in front of you, curl your upper body forward until your shoulders clear the floor. Hold this position for 3 seconds. Don't hold your breath. It helps to breathe out as you lift your shoulders up. Relax. Repeat 10 times. Build to 3 sets of 10. To challenge yourself, clasp your hands behind your head and keep your elbows out to the side. •Gluteal stretch: Lying on your back with both knees bent, rest the ankle of one leg over the knee of your other leg. Grasp the thigh of the bottom leg and pull that knee toward your chest. You will feel a stretch along the buttocks and possibly along the outside of your hip on the top leg. Hold this for 15 to 30 seconds. Repeat 3 times. •Extension exercise: Lie face down on the floor for 5 minutes. If this hurts too much, lie face down with a pillow under your stomach. This should relieve your leg or back pain. When you can lie on your stomach for 5 minutes without a pillow, then you can continue with the rest of this exercise.

Popular Health Tips

GERD: Causes, Symptoms and Treatment

MBBS, M.S. (Gold Medalist), MCh - Surgical Gastroenterology/G.I. Surgery
Gastroenterologist, Agra
GERD: Causes, Symptoms and Treatment

Gastroesophageal Reflux Disease (GERD) is a form of digestive disorder, which affects the lower oesophageal sphincters or the muscle ring present between the stomach and the food pipe. GERD incorporates the return of the contents of the stomach back to the oesophagus or food pipe. The functioning of the lower oesophageal sphincter is disrupted.

Causes:  Hiatal hernia is a common cause of GERD. An unhealthy lifestyle and diet may also lead to GERD. Intake of an excess amount of chocolates, fried food, coffee or alcohol triggers the chance of a reflux. GERD also occurs in obese people and pregnant women.

Symptoms: Heartburn, also known as acid indigestion, is the primary symptom of GERD. The affected person may feel a burning chest pain which starts from behind the breastbone and reaches up to the throat. The feeling can be defined as food coming back to the throat with a bitter, acidic taste. The burning sensation may last as long as two hours.

Other symptoms include:

  1. Excess saliva secretion
  2. Chronic conditions of sore throat
  3. Laryngitis
  4. Gum inflammation
  5. Tooth cavities
  6. Unpleasant breath

In order to diagnose GERD, several tests may be conducted . They are:

  1. An X-Ray of the upper part of the digestive system.
  2. Endoscopy to examine the inner part of the oesophagus.
  3. Ambulatory acid test for monitoring the amount of acid within the oesophagus.
  4. An oesophageal impedance test to measure substance movement inside the oesophagus.

Treatment

  1. A person must make several changes to his daily lifestyle and diet plan for treatment of GERD.
  2. Food and beverages like chocolates, fatty food, coffee, alcohol and peppermint should be avoided in order to reduce the weakening of the lower oesophageal sphincter. Several food items irritate the damaged oesophageal lining and should also be avoided. They include citrus fruits, tomato and pepper.
  3. Smoking cigarettes results in weakening of the lower oesophageal sphincter and should be stopped to reduce GERD.
  4. One should elevate the head of the bed on which he or she sleeps on blocks measuring 6 inches. This reduces the heartburn as gravity minimizes stomach reflux to return to the oesophagus.
  5. Over the counter medicines can be used to cure GERD. Antacids are a good example and neutralize the acid in the oesophagus and stomach, reducing heartburn. Combining antacids with foaming agents is also effective. A foam barrier is formed over the stomach, preventing the occurrence of acid reflux.
  6. Medicines for reducing acid in the stomach are prescribed in cases of chronic GERD, which include H2 blockers by the likes of cimetidine, famotidine or nizatidine.

GERD is a digestive disorder, which causes disruption in digestion, as reflux from the stomach is returned to the oesophagus. Proper treatment measures should be taken. If you wish to discuss about any specific problem, you can consult a Gastroenterologist.

3227 people found this helpful

GERD - Causes, Symptoms And Treatment!

MBBS, MS - General Surgery, MCh - Surgical Gastroenterology/G.I. Surgery
Gastroenterologist, Chennai
GERD - Causes, Symptoms And Treatment!

Gastroesophageal Reflux Disease (GERD) is a form of digestive disorder, which affects the lower oesophageal sphincters or the muscle ring present between the stomach and the food pipe. GERD incorporates the return of the contents of the stomach back to the oesophagus or food pipe. The functioning of the lower oesophageal sphincter is disrupted.

Causes:  Hiatal hernia is a common cause of GERD. An unhealthy lifestyle and diet may also lead to GERD. Intake of an excess amount of chocolates, fried food, coffee or alcohol triggers the chance of a reflux. GERD also occurs in obese people and pregnant women.

Symptoms: Heartburn, also known as acid indigestion, is the primary symptom of GERD. The affected person may feel a burning chest pain which starts from behind the breastbone and reaches up to the throat. The feeling can be defined as food coming back to the throat with a bitter, acidic taste. The burning sensation may last as long as two hours.

Other symptoms include:

  1. Excess saliva secretion
  2. Chronic conditions of sore throat
  3. Laryngitis
  4. Gum inflammation
  5. Tooth cavities
  6. Unpleasant breath

In order to diagnose GERD, several tests may be conducted . They are:

  1. An X-Ray of the upper part of the digestive system.
  2. Endoscopy to examine the inner part of the oesophagus.
  3. Ambulatory acid test for monitoring the amount of acid within the oesophagus.
  4. An oesophageal impedance test to measure substance movement inside the oesophagus.

Treatment

  1. A person must make several changes to his daily lifestyle and diet plan for treatment of GERD.
  2. Food and beverages like chocolates, fatty food, coffee, alcohol and peppermint should be avoided in order to reduce the weakening of the lower oesophageal sphincter. Several food items irritate the damaged oesophageal lining and should also be avoided. They include citrus fruits, tomato and pepper.
  3. Smoking cigarettes results in weakening of the lower oesophageal sphincter and should be stopped to reduce GERD.
  4. One should elevate the head of the bed on which he or she sleeps on blocks measuring 6 inches. This reduces the heartburn as gravity minimizes stomach reflux to return to the oesophagus.
  5. Over the counter medicines can be used to cure GERD. Antacids are a good example and neutralize the acid in the oesophagus and stomach, reducing heartburn. Combining antacids with foaming agents is also effective. A foam barrier is formed over the stomach, preventing the occurrence of acid reflux.
  6. Medicines for reducing acid in the stomach are prescribed in cases of chronic GERD, which include H2 blockers by the likes of cimetidinefamotidine or nizatidine.

GERD is a digestive disorder, which causes disruption in digestion, as reflux from the stomach is returned to the oesophagus. Proper treatment measures should be taken. In case you have a concern or query you can always consult an expert & get answers to your questions! 

2923 people found this helpful

Gastroesophageal Reflux Disease (GERD)

MBBS, MS - General Surgery , DNB (General Surgery), MNAMS (Membership of the National Academy), Fellow HPB Surgery & Liver Transplant (Singapore) , FICS - RPSLH - RPSLH
Gastroenterologist, Hyderabad
Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD) is a form of digestive disorder, which affects the lower oesophageal sphincters or the muscle ring present between the stomach and the food pipe. GERD incorporates the return of the contents of the stomach back to the oesophagus or food pipe. The functioning of the lower oesophageal sphincter is disrupted.

Causes:  Hiatal hernia is a common cause of GERD. An unhealthy lifestyle and diet may also lead to GERD. Intake of an excess amount of chocolates, fried food, coffee or alcohol triggers the chance of a reflux. GERD also occurs in obese people and pregnant women.

Symptoms: Heartburn, also known as acid indigestion, is the primary symptom of GERD. The affected person may feel a burning chest pain which starts from behind the breastbone and reaches up to the throat. The feeling can be defined as food coming back to the throat with a bitter, acidic taste. The burning sensation may last as long as two hours.

Other symptoms include:

  1. Excess saliva secretion
  2. Chronic conditions of sore throat
  3. Laryngitis
  4. Gum inflammation
  5. Tooth cavities
  6. Unpleasant breath

In order to diagnose GERD, several tests may be conducted . They are:

  1. An X-Ray of the upper part of the digestive system.
  2. Endoscopy to examine the inner part of the oesophagus.
  3. Ambulatory acid test for monitoring the amount of acid within the oesophagus.
  4. An oesophageal impedance test to measure substance movement inside the oesophagus.

Treatment

  1. A person must make several changes to his daily lifestyle and diet plan for treatment of GERD.
  2. Food and beverages like chocolates, fatty food, coffee, alcohol and peppermint should be avoided in order to reduce the weakening of the lower oesophageal sphincter. Several food items irritate the damaged oesophageal lining and should also be avoided. They include citrus fruits, tomato and pepper.
  3. Smoking cigarettes results in weakening of the lower oesophageal sphincter and should be stopped to reduce GERD.
  4. One should elevate the head of the bed on which he or she sleeps on blocks measuring 6 inches. This reduces the heartburn as gravity minimizes stomach reflux to return to the oesophagus.
  5. Over the counter medicines can be used to cure GERD. Antacids are a good example and neutralize the acid in the oesophagus and stomach, reducing heartburn. Combining antacids with foaming agents is also effective. A foam barrier is formed over the stomach, preventing the occurrence of acid reflux.
  6. Medicines for reducing acid in the stomach are prescribed in cases of chronic GERD, which include H2 blockers by the likes of cimetidine, famotidine or nizatidine.

GERD is a digestive disorder, which causes disruption in digestion, as reflux from the stomach is returned to the oesophagus. Proper treatment measures should be taken.

3779 people found this helpful

Safe and Unsafe Medications to Take While Pregnant

MBBS, DGO, MD - Obstetrics & Gynaecology, MRCOG
Gynaecologist, Delhi
Safe and Unsafe Medications to Take While Pregnant

Which medicines are safe to use during Pregnancy?

Normal pregnancy lasts for 38 to 42 weeks. However, there may be times during these weeks that you may have some physical issues such as vomiting, backache, and loose stools etc which require treatment with medicines.

Therefore, monitoring and managing these physical conditions becomes necessary to ensure a normal delivery.Management consists of both medicines and rehabilitation.Medicines are considered to be the first line of treatment; however, the health care provider needs to take care while prescribing medicines during pregnancy taking into consideration the harmful effects they can have on both – the mother and the foetus.  Medicines pass on via the placenta from the mother to the foetus. Hence, before prescribing any medicine the provider should check the possibilities of the medicine causing any congenital defect. You should avoid medicines from the time of conception till the first 10 weeks, as this is the time when the foetus is most prone to the get permanent congenital deformities. Medicines given in the later stages (after 10 weeks) may cause systemic damage. For example NSAIDs (Non Steroidal Anti-Inflammatory Drugs) may lead to problems during labour or organ defects in the foetus.

Therefore, medicines should always be avoided during pregnancy. Still there are certain medicines, which can be taken but after consulting your physician. Let’s discuss the medicines that are safe during pregnancy.

The following is a list of medicines and their effects during pregnancy:

1. Analgesic Medicines

Paracetamol Safe
NSAIDs, such as aspirin May cause heart abnormalities in the third trimester

2. Opiates

Codeine Effective in low doses
Hydrocodone Effective in low doses
Hydromorphone Effective in low doses

3. Anaesthetics

Etomidate Unknown always ask your provider
Ketamine Avoid during the last trimester
Lorazepam Avoid for severe conditions, safe for short periods

4. Thrombolytics - The possible advantages of this class may balance the risk during pregnancy. Common medicines used are: Alteplase, Reteplase, Streptokinase, Urokinase.

5. Antidotes

Hydroxycobalamin antidote: cyanide Safe
Methylene blue antidote: methemoglobinemia Has a potential risk to the mother and foetus

6. Penicillins

First generation: penicillin G, benzathine penicillin, Bicillin, penicillin VK Safe
Second generation: oxacillin, dicloxacillin, nafcillin Safe

7. Cardiac agents

Adenosine Safe
Digoxin Not advised in third trimester
Lidocaine Safe

8. Diabetes: Insulin is safe to use during diabetes.

9. Antacids

Famotidine Low risk
Ranitidine Safe

10. Corticosteroids: Advised for short term use

Cetirizine Almost safe
Chlorpheniramine Safe

Always talk to your physician in case of any complication and before taking any medicine given above.

Taking Medicines during Pregnancy: Safe and Unsafe Medications

MBBS, DGO, MD - Obstetrics & Gynaecology, MRCOG
Gynaecologist, Delhi
Taking Medicines during Pregnancy: Safe and Unsafe Medications

Normal pregnancy lasts for 38 to 42 weeks. However, there may be times during these weeks that you may have some physical issues such as vomiting, backache, and loose stools etc which require treatment with medicines.

Therefore, monitoring and managing these physical conditions becomes necessary to ensure a normal delivery. Management consists of both medicines and rehabilitation. Medicines are considered to be the first line of treatment; however, the health care provider needs to take care while prescribing medicines during pregnancy taking into consideration the harmful effects they can have on both – the mother and the foetus.  Medicines pass on via the placenta from the mother to the foetus. Hence, before prescribing any medicine the provider should check the possibilities of the medicine causing any congenital defect. You should avoid medicines from the time of conception till the first 10 weeks, as this is the time when the foetus is most prone to the get permanent congenital deformities. Medicines given in the later stages (after 10 weeks) may cause systemic damage. For example NSAIDs (Non Steroidal Anti-Inflammatory Drugs) may lead to problems during labour or organ defects in the foetus.

Therefore, medicines should always be avoided during pregnancy. Still there are certain medicines, which can be taken but after consulting your physician. Let’s discuss the medicines that are safe during pregnancy.

The following is a list of medicines and their effects during pregnancy:

1. Analgesic Medicines

Paracetamol Safe
NSAIDs, such as aspirin May cause heart abnormalities in the third trimester

2. Opiates 

Codeine Effective in low doses
Hydrocodone Effective in low doses
Hydromorphone Effective in low doses

3. Anaesthetics 

Etomidate Unknown always ask your provider
Ketamine Avoid during the last trimester
Lorazepam Avoid for severe conditions, safe for short periods

4. Thrombolytics - The possible advantages of this class may balance the risk during pregnancy. Common medicines used are: Alteplase, Reteplase, Streptokinase, Urokinase.

5. Antidotes

Hydroxycobalamin antidote: cyanide Safe
Methylene blue antidote: methemoglobinemia Has a potential risk to the mother and foetus

6. Penicillins

First generation: penicillin G, benzathine penicillin, Bicillin, penicillin VK Safe
Second generation: oxacillin, dicloxacillin, nafcillin Safe

7. Cardiac agents

Adenosine Safe
Digoxin Not advised in third trimester
Lidocaine Safe

8. Diabetes: Insulin is safe to use during diabetes.

9. Antacids

Famotidine Low risk
Ranitidine Safe

10. Corticosteroids: Advised for short term use

Cetirizine Almost safe
Chlorpheniramine Safe

Always talk to your physician in case of any complication and before taking any medicine given above.

4 people found this helpful

Table of Content

About Famotidine 40 MG Tablet
When is Famotidine 40 MG Tablet prescribed?
What are the contraindications of Famotidine 40 MG Tablet?
What are the side effects of Famotidine 40 MG Tablet?
Key highlights of Famotidine 40 MG Tablet
What are the substitutes for Famotidine 40 MG Tablet?
What are the dosage instructions?
Where is the Famotidine 40 MG Tablet approved?
What are the interactions for Famotidine 40 MG Tablet?