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Exemptia 20mg/0.4ml Prefilled Syringe

Manufacturer: Zydus Cadila
Medicine composition: Adalimumab
Prescription vs.OTC: Prescription by Doctor required

Exemptia 20mg/0.4ml Prefilled Syringe is a medicine used in the treatment of psoriatic arthritis, rheumatoid pneumonia, Crohn's disease, ankylosing spondylitis, chronic psoriasis, ulcerative colitis, hidradenitis suppurativa, and juvenile idiopathic arthritis. It is an anti inflammatory, Tumor Necrosis Factor (TNF) binding biological medicine.

Exemptia 20mg/0.4ml Prefilled Syringe should not be taken if you are having any kind of infection, are allergic to it or any ingredient in it, using anakinra, abatacept, or if you are already on some other TNF blocker. You should also consult your doctor before taking Exemptia 20mg/0.4ml Prefilled Syringe if you already had hepatitis B, tuberculosis, heart problems, liver problems in the past, or any other infections that keeps coming back. Exemptia 20mg/0.4ml Prefilled Syringe should also be avoided if you are taking in medicine or supplements or if you are pregnant, plan on becoming pregnant, or you are breastfeeding.

The side effects of Exemptia 20mg/0.4ml Prefilled Syringe include headache, mild pain, back pain, swelling at site of injection, nausea, runny nose. Immediately see a doctor if you experience severe allergic reactions, extreme pain, sudden mood changes, sudden weight loss or weight gain. In many cases certain type of cancers or lymphoma have been reported and past infections like TB have also been reactivated.

Exemptia 20mg/0.4ml Prefilled Syringe is available as an injection given under the skin. You should not inject it into the muscles. It should always be administered as per the dosage prescribed by the doctor on the basis of your physiological conditions.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Rheumatologist before using this medicine.

In addition to its intended effect, Exemptia 20mg/0.4ml Prefilled Syringe may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Headache
Sinus inflammation
Rash
Upper respiratory tract infection
Injection site reaction.
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Adfrar 40mg prefilled syringe is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
Does this affect kidney function?
There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Are there any missed dose instructions?
If you miss a dose of Adalimumab, please consult your doctor.
Exemptia 20mg/0.4ml Prefilled Syringe combines to TNF-alpha and obstructs the interaction with p55 as well as with p75 cell surface of TNF receptors. Exemptia 20mg/0.4ml Prefilled Syringe lyses the surface with TNF releasing cells within in vitro.
What are you using Exemptia 20mg/0.4ml Prefilled Syringe for?
Rheumatoid Arthritis
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

What Precautions should the patient take when he is taking Exemptia 40injection course?

MBBS
General Physician, Mumbai
What Precautions should the patient take when he is taking Exemptia 40injection course?
Tips- At the time of taking the injection you should not be having any kind of infection and should be vitally stable and any vaccination prior to this should not be given

Which injection is good for ankylosing spondylitis either exemptia 40 mg. Or. Infimab 100 mg? Please tell me.

Erasmus Mundus Master in Adapted Physical Activity, MPT, BPTh/BPT
Physiotherapist, Chennai
Which injection is good for ankylosing spondylitis either exemptia 40 mg. Or. Infimab 100 mg?
Please tell me.
Ankylosing spondylitis Ankylosing spondylitis is a cause of back pain in adolescents and young adults. Ankylosing spondylitis is a form of chronic inflammation of the spine and the sacroiliac joints Chronic inflammation in these areas causes pain and stiffness in and around the spine, including the neck, middle back, lower back, and buttocks. Over time, chronic inflammation of the spine (spondylitis) can lead to a complete cementing together (fusion) of the vertebrae, a process referred to as ankylosis. Ankylosis causes loss of mobility of the spine. Pt treatment deep breathing for lung expansion and stretching exercises to improve spine and joint mobility. Are also advised to sleep on a firm mattress and avoid the use of a pillow in order to prevent spine curvature. Aerobic exercise is generally encouraged as it promotes full expansion of the breathing muscles and opens the airways of the lungs.

My son is suffering form ankylosing spondylitis since 10 years. He has taken embark for 4 years monthly once and exemptia 40 mg for 2 years. After using exemptia he got TB and now we stopped all medicine related to ankylosing spondylitis except painkillers. Now as TB medicine course is over, can I take exemptia. Why I'm asking is that I'm having slight pain in morning. As a preventive measure can I take the injection. And also please suggest can I take safe or exemptia. Thanks.

MBBS, MD TUBERCULOSIS AND CHEST DISEASES, Diploma in Tuberculosis & Chest Diseases, Diploma in Tropical Medicine and Hygiene
Pulmonologist, Kolkata
My son is suffering form ankylosing spondylitis since 10 years. He has taken embark for 4 years monthly once and exem...
Right now it's not advisable to resume embark or exemptia due to risk of recurrence of tuberculosis relapse. Continue conservative management of ankylosing spondylitis with analgesics and exercise. Wish you good health.

He have rheumatoid arthritis. Doctor give him exemptia injection. But no improvement in his health condition. Pain occurs in all joints of body. He is taking folitrax tab once a week and exemptia injection once in 14 days. Suggest something to reduce pain.

MBA (Healthcare), Bachelor of Unani Medicine and Surgery (B.U.M.S)
Unani Specialist, Patna
He have rheumatoid arthritis. Doctor give him exemptia injection. But no improvement in his health condition. Pain oc...
I prescribed some unani medicine for rheumatoid arthritis. There is no side effects 1 habbe suranjan (hamdard) 2tabx 2 = 1 month 2. Majun chobchini (hamdard) 10 gm to be taken with water at bed time. 3. Roghan suranjan this oil to be massaged in all part of join.
3 people found this helpful

I have been diagnosed with ankylosing spondylitis and I am taking exemptia shots every three weeks. I am moderately fit. I need to know if I need tho make any dietary modifications to maintain my health.

MPT - Orthopedic Physiotherapy, Fellowship In Orthopaedic Rehabilitation (FOR) Advanced Diploma in Nutrition & Diet
Physiotherapist, Kolkata
I have been diagnosed with ankylosing spondylitis and I am taking exemptia shots every three weeks. I am moderately f...
Absolutely .You need to take Antinflammatory Diet. Diet and Nutritional Therapy can make your condition much better and that too without any side effects. Consult with me for a professional medical nutrition therapy guidelines. Good luck!
1 person found this helpful

Popular Health Tips

Uveitis - Do You Know It Can Increase The Risk Of Other Diseases?

MBBS, MS - Ophthalmology
Ophthalmologist, Ghaziabad
Uveitis - Do You Know It Can Increase The Risk Of Other Diseases?

Uveitis is a set of inflammatory diseases that results in the swelling and damaging of the eye tissue. It can lead to temporary or permanent loss of vision. This disease often affects a part of the eye called the uvea, from which it has derived its name. It can affect people of all ages and can last from a short to long period of time. Ophthalmologists categorize uveitis into four major parts posterior uveitis, anterior uveitis, panuveitis uveitis and intermediate uveitis. This disease can be infectious or noninfectious, depending on the nature of the infection.

What causes uveitis and what are the major risk factors?
This disease is caused by the eye's inflammatory response and is caused by a series of potential factors such as the following:

  • Immune system attack from the body
  • Eye bruises
  • Eye infection or tumor within the eye
  • Foreign toxins that penetrate the eye

What are the diseases associated with uveitis?
Uveitis is associated with a range of diseases such as multiple sclerosis, Behcet's syndrome, Vogt-Koyanagi-Harada's (VKH) disease, psoriasis, herpes zoster infection, tuberculosis, rheumatoid arthritis, ulcerative colitis, toxoplasmosis, and cytomegalovirus (CMV) retinitis.

What are the typical symptoms of uveitis?
One or both eyes can be affected by uveitis. Some of the common symptoms include pain in the eye, light sensitivity and blurred and dark spots in vision. Moreover, the symptoms might vary from person to person and greatly depends on the type of inflammation. The symptoms also vary according to the type of uveitis.

What is the detection process?
The process of detection starts with a patient's medical history followed by several medical tests to rule out autoimmune disorders. This is followed by an evaluation of the central nervous system to rule out multiple sclerosis. Some of the other tests conducted by ophthalmologists include measuring the ocular pressure, slit lamp exam, funduscopic exam and visual acuity test.

The primary aim of the treatment is to eradicate inflammation, restore vision, prevent tissue damage and reduce pain. The treatment plan depends on the type of uveitis a patient displays. Doctors often suggest a dose of corticosteroid eye drops to arrest the infection in and around the eye. Other treatment methods include the prescription of immunosuppressive agents.

Furthermore, a doctor may suggest steroidal medication in the form of an eye drop, pill or injection. It can also be surgically infused into the eye. Some other agents used for treatment are azathioprine, methotrexate and mycophenolate. Medications such as these require regular monitoring of the blood to check for any side effects. Doctors also suggest biologics such as infliximab, rituximab, and adalimumab. Most of these drugs have a specific target in the immune system.

In case you have a concern or query you can always consult an expert & get answers to your questions!

5044 people found this helpful

Uveitis - Know How It Can Be Diagnosed!

ABC
Ophthalmologist, Jodhpur
Uveitis - Know How It Can Be Diagnosed!

Uveitis is a set of inflammatory diseases that results in the swelling and damaging of the eye tissue. It can lead to temporary or permanent loss of vision. This disease often affects a part of the eye called the uvea, from which it has derived its name. It can affect people of all ages and can last from a short to long period of time. Ophthalmologists categorize uveitis into four major parts posterior uveitis, anterior uveitis, panuveitis uveitis and intermediate uveitis. This disease can be infectious or noninfectious, depending on the nature of the infection.

What causes uveitis and what are the major risk factors?
This disease is caused by the eye's inflammatory response and is caused by a series of potential factors such as the following:

  • Immune system attack from the body
  • Eye bruises
  • Eye infection or tumor within the eye
  • Foreign toxins that penetrate the eye

What are the diseases associated with uveitis?
Uveitis is associated with a range of diseases such as multiple sclerosis, Behcet's syndrome, Vogt-Koyanagi-Harada's (VKH) disease, psoriasis, herpes zoster infection, tuberculosis, rheumatoid arthritis, ulcerative colitis, toxoplasmosis, and cytomegalovirus (CMV) retinitis.

What are the typical symptoms of uveitis?

One or both eyes can be affected by uveitis. Some of the common symptoms include pain in the eye, light sensitivity and blurred and dark spots in vision. Moreover, the symptoms might vary from person to person and greatly depends on the type of inflammation. The symptoms also vary according to the type of uveitis.

What is the detection process?
The process of detection starts with a patient's medical history followed by several medical tests to rule out autoimmune disorders. This is followed by an evaluation of the central nervous system to rule out multiple sclerosis. Some of the other tests conducted by ophthalmologists include measuring the ocular pressure, slit lamp exam, funduscopic exam and visual acuity test.

The primary aim of the treatment is to eradicate inflammation, restore vision, prevent tissue damage and reduce pain. The treatment plan depends on the type of uveitis a patient displays. Doctors often suggest a dose of corticosteroid eye drops to arrest the infection in and around the eye. Other treatment methods include the prescription of immunosuppressive agents.

Furthermore, a doctor may suggest steroidal medication in the form of an eye drop, pill or injection. It can also be surgically infused into the eye. Some other agents used for treatment are azathioprine, methotrexate and mycophenolate. Medications such as these require regular monitoring of the blood to check for any side effects. Doctors also suggest biologics such as infliximab, rituximab, and adalimumab. Most of these drugs have a specific target in the immune system.

In case you have a concern or query you can always consult an expert & get answers to your questions!

6486 people found this helpful

What Is Uveitis? How Can It Be Treated?

Super-Speciality Trained Ophthalmologists
Ophthalmologist, Delhi
What Is Uveitis? How Can It Be Treated?

Uveitis is a set of inflammatory diseases that results in the swelling and damaging of the eye tissue. It can lead to temporary or permanent loss of vision. This disease often affects a part of the eye called the uvea, from which it has derived its name. It can affect people of all ages and can last from a short to long period of time. Ophthalmologists categorize uveitis into four major parts posterior uveitis, anterior uveitis, panuveitis uveitis and intermediate uveitis. This disease can be infectious or noninfectious, depending on the nature of the infection.

What causes uveitis and what are the major risk factors?
This disease is caused by the eye's inflammatory response and is caused by a series of potential factors such as the following:

  • Immune system attack from the body
  • Eye bruises
  • Eye infection or tumor within the eye
  • Foreign toxins that penetrate the eye

What are the diseases associated with uveitis?
Uveitis is associated with a range of diseases such as multiple sclerosis, Behcet's syndrome, Vogt-Koyanagi-Harada's (VKH) disease, psoriasis, herpes zoster infection, tuberculosis, rheumatoid arthritis, ulcerative colitis, toxoplasmosis, and cytomegalovirus (CMV) retinitis.

What are the typical symptoms of uveitis?
One or both eyes can be affected by uveitis. Some of the common symptoms include pain in the eye, light sensitivity and blurred and dark spots in vision. Moreover, the symptoms might vary from person to person and greatly depends on the type of inflammation. The symptoms also vary according to the type of uveitis.

What is the detection process?
The process of detection starts with a patient's medical history followed by several medical tests to rule out autoimmune disorders. This is followed by an evaluation of the central nervous system to rule out multiple sclerosis. Some of the other tests conducted by ophthalmologists include measuring the ocular pressure, slit lamp exam, funduscopic exam and visual acuity test.

The primary aim of the treatment is to eradicate inflammation, restore vision, prevent tissue damage and reduce pain. The treatment plan depends on the type of uveitis a patient displays. Doctors often suggest a dose of corticosteroid eye drops to arrest the infection in and around the eye. Other treatment methods include the prescription of immunosuppressive agents.

Furthermore, a doctor may suggest steroidal medication in the form of an eye drop, pill or injection. It can also be surgically infused into the eye. Some other agents used for treatment are azathioprine, methotrexate and mycophenolate. Medications such as these require regular monitoring of the blood to check for any side effects. Doctors also suggest biologics such as infliximab, rituximab, and adalimumab. Most of these drugs have a specific target in the immune system.

4558 people found this helpful

Juvenile Rheumatoid Arthritis - Know More About It!

MBBS, MD - Internal Medicine, MRCEM(UK), MEM, Diploma in Rheumatology, PGCC - Rheumatology, MACEP, FCCS
Rheumatologist, Kolkata
Juvenile Rheumatoid Arthritis - Know More About It!

Juvenile rheumatoid arthritis also known as juvenile idiopathic arthritis is a commonly occurring arthritis in children under the age of 15. Some common problems that are faced by patients with this disease include stiffness, joint pain, and swelling. While the symptoms might persist for a few months for some patients, for others it might continue for the rest of their lives. Patients might face serious complications such as inflammation of the eye, problems related to growth etc. The treatment of this condition focuses on preventing the bones from getting damaged, pain control and improving the function of the body.

What are some of the common symptoms of juvenile arthritis?

  1. Pain: A child suffering from juvenile rheumatoid arthritis might face extreme pain in the joints. They might limp after a nap or night sleep due to pain or stiff joints.

  2. Swelling: Larger joints such as the knee might swell frequently. The swelling might occur in smaller joints too.

  3. Stiffness: In addition to limping the child might appear rough and clumsy after waking from night sleep or a nap.

Other conditions could include rashes, swollen lymph nodes, frequent fever, headache, etc.

What are the causes of Juvenile Rheumatoid Arthritis?

Juvenile Rheumatoid Arthritis occurs when the immune system of the body attacks its own tissues and cells. It is still unclear as to why it happens, although, researchers believe that the environment and heredity have a role to play. Certain genetic mutations might make a child more vulnerable and susceptible to microbes that can trigger this condition.

What are the complications involved?

There could be several complications that might arise due to this condition. It is, therefore, wise to keep a close watch on the child. Seeking immediate medical attention can go a long way in mitigating the risk of these complications.

  • Problems related to the eye: Juvenile Rheumatoid arthritis can damage the eye by causing an inflammation known as uveitis. If this condition is not treated, it might result in other conditions such as glaucoma, cataracts, blindness etc.

  • Growth problems: Juvenile rheumatoid arthritis could result in growth problems. To treat this, a child would require a dose of corticosteroid.

How to diagnose juvenile arthritis?

It is not very easy to diagnose juvenile arthritis. Doctors often prescribe blood tests to get an idea of erythrocyte sedimentation rate, rheumatoid factor, C-reactive protein, anti-nuclear antibody, cyclic citrullinated peptide etc. A doctor might also prescribe imaging tests such as X-rays, MRI etc to detect congenital defects, fractures, tumors etc.

What are the treatment options available?

The overall treatment goal is to control symptoms, prevent joint damage, and maintain function. Oral steroids such as prednisone, deflazocort may be used in certain situations, but only for as short a time and at the lowest dose possible. Some of the medications that are prescribed for this condition include NSAID such as ibuprofen and naproxen, DMARD such as methotrexate and leflunomide, TNF blockers such as adalimumab and etanercept, immune suppressants such as rituximab. In addition to this, doctors would also prescribe exercises and therapies.

Options Other Than Knee Replacement

MBBS, M. S., SR (AIIMS),FIJRS (SOUTH KOREA)
Orthopedist, Delhi
Options Other Than Knee Replacement

There is no cure for arthritis but there are a number of treatments that may help relieve the pain and disability it can cause.

  • As with other arthritic conditions, initial treatment of arthritis of the knee is nonsurgical. Your doctor may recommend a range of treatment options.
  • Lifestyle modifications. Some changes in your daily life can protect your knee joint and slow the progress of arthritis.
  • Minimize activities that aggravate the condition, such as climbing stairs.
  • Switching from high impact activities (like jogging or tennis) to lower impact activities (like swimming or cycling) will put less stress on your knee.
  • Losing weight can reduce stress on the knee joint, resulting in less pain and increased function.
  • Physical therapy. Specific exercises can help increase range of motion and flexibility, as well as help strengthen the muscles in your leg. Your doctor or a physical therapist can help develop an individualized exercise program that meets your needs and lifestyle.
  • Assistive devices. Using devices such as a cane, wearing shock-absorbing shoes or inserts, or wearing a brace or knee sleeve can be helpful. A brace assists with stability and function, and may be especially helpful if the arthritis is centered on one side of the knee. There are two types of braces that are often used for knee arthritis: an" unloader" brace shifts weight away from the affected portion of the knee, while a" support" brace helps support the entire knee load.
  • Other remedies. Applying heat or ice, using pain-relieving ointments or creams, or wearing elastic bandages to provide support to the knee may provide some relief from pain.
  • Medications. Several types of drugs are useful in treating arthritis of the knee. Because people respond differently to medications, your doctor will work closely with you to determine the medications and dosages that are safe and effective for you.
  • Over-the-counter, non-narcotic pain relievers and anti-inflammatory medications are usually the first choice of therapy for arthritis of the knee. Acetaminophen is a simple, over-the-counter pain reliever that can be effective in reducing arthritis pain.
  • Like all medications, over-the-counter pain relievers can cause side effects and interact with other medications you are taking. Be sure to discuss potential side effects with your doctor.
  • Another type of pain reliever is a nonsteroidal anti-inflammatory drug, or nsaid (pronounced" en-said"). Nsaids, such as ibuprofen and naproxen, are available both over-the-counter and by prescription. A cox-2 inhibitor is a special type of nsaid that may cause fewer gastrointestinal side effects. Common brand names of cox-2 inhibitors include celebrex (celecoxib) and mobic (meloxicam, which is a partial cox-2 inhibitor). A cox-2 inhibitor reduces pain and inflammation so that you can function better. If you are taking a cox-2 inhibitor, you should not use a traditional nsaid (prescription or over-the-counter). Be sure to tell your doctor if you have had a heart attack, stroke, angina, blood clot, hypertension, or if you are sensitive to aspirin, sulfa drugs or other nsaids.
  • Corticosteroids (also known as cortisone) are powerful anti-inflammatory agents that can be injected into the joint these injections provide pain relief and reduce inflammation; however, the effects do not last indefinitely. Your doctor may recommend limiting the number of injections to three or four per year, per joint, due to possible side effects.
  • In some cases, pain and swelling may" flare" immediately after the injection, and the potential exists for long-term joint damage or infection. With frequent repeated injections, or injections over an extended period of time, joint damage can actually increase rather than decrease.
  • Disease-modifying anti-rheumatic drugs (dmards) are used to slow the progression of rheumatoid arthritis. Drugs like methotrexate, sulfasalazine, and hydroxychloroquine are commonly prescribed.
  • In addition, biologic dmards like etanercept (embril) and adalimumab (humira) may reduce the body's overactive immune response. Because there are many different drugs today for rheumatoid arthritis, a rheumatology specialist is often required to effectively manage medications.
  • Viscosupplementation involves injecting substances into the joint to improve the quality of the joint fluid.
  •  Glucosamine and chondroitin sulfate, substances found naturally in joint cartilage, can be taken as dietary supplements. Although patient reports indicate that these supplements may relieve pain, there is no evidence to support the use of glucosamine and chondroitin sulfate to decrease or reverse the progression of arthritis.
5 people found this helpful

Table of Content

About Exemptia 20mg/0.4ml Prefilled Syringe
When is Exemptia 20mg/0.4ml Prefilled Syringe prescribed?
What are the side effects of Exemptia 20mg/0.4ml Prefilled Syringe ?
Key highlights of Exemptia 20mg/0.4ml Prefilled Syringe
What are the dosage instructions?
How does medicine works?