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Overview

Altaxel 300 MG Infusion

Manufacturer: Alkem Laboratories Ltd
Medicine composition: Paclitaxel
Prescription vs.OTC: Prescription by Doctor required

Altaxel 300 MG Infusion is an anticancer medicine, used in chemotherapy to treat a number of cancers. Primarily it is used in the treatment of breast cancer and ovarian cancer. It is sold under the trade name of Taxol. Altaxel 300 MG Infusion is categorized as a plant alkaloid, a taxane and a antimicrotublue agent. Altaxel 300 MG Infusion is injected into the body by injection or infusion.

Altaxel 300 MG Infusion is a type of irritant that may cause an inflammation of your vein through which it is being given. Other side effects or reactions that you may experience on taking Altaxel 300 MG Infusion are nausea, vomiting tendency, hair loss, diarrhea, hypersensitivity, mucositis, skin rash, flushing, blurred vision, numbness, dizziness, fever, paleness, difficulty in breathing, cough, sweating, slow or irregular heartbeat and chest pain. In certain adverse cases, it may cause major arthralgia, myalgia. It is advised that you seek medical attention if you are afflicted with any of these side effects.

Before taking Altaxel 300 MG Infusion discuss with your doctor if you have any of the conditions mentioned below:

  • If you are taking any prescriptive or over the counter drugs, herbal medications or dietary supplements.
  • If you are planning to take any immunization, vaccination or radiation treatment anytime soon.
  • If you are pregnant or are planning to become pregnant or are nursing a baby.
  • If you have any allergies, bacterial or viral infections.
  • If you are under 18 years of age.
  • If you have heart, liver, kidney or bone marrow disorders.

Do not get pregnant while under Altaxel 300 MG Infusion treatment. Use contraception for both men and women. Should you become pregnant, notify your doctor. The dosage is determined by your doctor according to your individual specifications and condition. The usual dose for treatment in ovarian and breast cancer is of two types; one is giving about 175 mg for three hours every three weeks followed by a Cisplatin therapy. And the second one is giving 135 mg for 24 hours every three weeks followed by the same cisplatin therapy.

Altaxel 300 MG Infusion is used in the treatment of cancer that affects the female reproductive system.
Altaxel 300 MG Infusion is used in the treatment of breast cancer.
Altaxel 300 MG Infusion is used in the treatment of Non-Small Cell Lung Cancer which is a type of cancer that affects the lungs.
Altaxel 300 MG Infusion is used in the treatment of Kaposi's Sarcoma which is a type of cancer that develops under the skin in the lining of mouth, nose, and throat.
Not recommended in the patients with known allergy to Altaxel 300 MG Infusion.
Neutrophils count
Not recommended in the patients with neutrophils count less than 1,500 cells/mm3
In addition to its intended effect, Altaxel 300 MG Infusion may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Neutropenia Major Common
Difficult or painful urination Major Common
Dizziness when getting up suddenly from a sitting position Major Common
Fever and chills Major Common
Pale skin Major Common
Allergic Skin Reaction Major Common
Mouth ulcers Major Common
Difficulty in breathing Major Less Common
Chest discomfort Major Less Common
Swelling and redness at the injection site Minor Common
Diarrhea Minor Common
Hair loss or thinning of the hair Minor Common
Nausea and Vomiting Minor Common
Joint pain Minor Common
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 27 hours.
What is the onset of action?
The peak effect of this medicine can be observed in less than an hour.
Are there any pregnancy warnings?
This medicine is not recommended for pregnant women.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
This medicine is not recommended in breastfeeding women.
Below is the list of medicines, which have the same composition, strength and form as Altaxel 300 MG Infusion, and hence can be used as its substitute.
Intas Pharmaceuticals Ltd
Bms India Pvt. Ltd
Missed Dose instructions
It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of an overdose.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
cardiac conduction abnormalities Major
This medicine is known to cause serious heart conduction abnormalities. Inform the doctor if you have any heart diseases. Close monitoring of low blood pressure and decreased heartbeat is necessary.
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Clozapine Major
These medicines may further lower the white blood cell count if received together. Any symptoms of fever, diarrhea, sore throat, chills should be informed to the doctor. Close monitoring of blood cell count is necessary. An alternate medicine should be considered based on the clinical condition.
Diltiazem Moderate
Diltiazem may increase the concentration of Altaxel 300 MG Infusion and may cause serious effects like low white blood cells count, hair loss, nausea, and vomiting. Inform the doctor if you are receiving any antihypertensives before initiation of the treatment. An alternate medicine should be considered based on the clinical condition.
Atorvastatin Moderate
These medicines may increase the risk of nerve damage if given together. Any symptoms of numbness, tingling or burning sensation in feet, hands should be informed to the doctor. An alternate medicine should be considered based on the clinical condition.
Live vaccines Major
You may be at the risk of developing infections if these medicines are taken together. Inform the doctor if you had received either of these medicines. Your doctor may postpone therapy based on the condition.
What are you using Altaxel 300 MG Infusion for?
Breast Cancer

Popular Questions & Answers

Hello, My wife is suffering from angiosarcoma of breast with bones and liver mets doctors are giving her paclitaxel 130 weekly but no response Please advice any homeopath who can deal in angiosarcoma.

DHMS (Hons.)
Homeopath, Patna
Hello, It requires :underlying information to begine homoeopathic medication, please. Age of the patient, Dimensions of tumor, All sorts of reports in this regards. Image of her affected part. Tk, care.
2 people found this helpful

My mother has breast cancer. Her chemotherapy is going on. It is known to us that during the period of chemotherapy there is a chance of muscle pain. She sometimes suffers from that. It isn't possible to bring a physician every time. So I've to serve her. What should be the best way to give her a physiotherapy to reduce her muscle pain for that time. Please suggest something.

MD - Radiation Oncology, MBBS, DNB (Radiotherapy)
Oncologist, Howrah
Chemotherapy drugs such as paclitaxel or docetaxel may cause myalgia , arthralgia for few days after each cycle. Depending on the severity use of analgesics for few days will be helpful.
29 people found this helpful

My father has been diagnosed with Non-Small Cell Lung Cancer, Stage 4 with primary tumour in his Left Upper Lung and metastasis in Liver and Bone. The biopsy report has confirmed it to be adenocarcinoma. The cancer was detected while he was admitted at a hospital in Mumbai and was undergoing treatment for Acute Paraplegia which happened on 02 Nov 16, due to arteries-Venous Fistula at D-10 level resulting in oedema/ ischemia of the spine from D-5 to Conus. After two failed attempts of embolization, towards treatment of the AVF, surgical clipping of the fistula was undertaken on 10 Nov 16. As part of post-operative rehabilitation therapy for his paraplegia, he was given 65 session of Hyper-basic Oxygen Therapy at 2.4 ata pressure for about two and a half month and about two hour of Physiotherapy for the same duration. My father was recovering well and had started walking with the help of support (walker). MRI of the spine taken in mid Jan & Mid June 2017 indicates that the spinal cord oedema had improved significantly, although atrophy of the spine cord is still present. He complained of wheezing and breathing difficulty and towards ascertaining the cause a X-ray was taken on 23 Feb 17 which showed massive pleural effusion in his left lungs. A series of tests followed with the ultimate result as NSCLC Stage 3B. He was started with CCRT treatment which concluded on 05 May 17. During the treatment he was given daily dose of radiation therapy using IGRT (60 Gy/ 30 #/6 weeks) and weekly chemotherapy with paclitaxel (150 mg) & Carboplatin (300 mg) for 6 weeks. Despite the treatment, the cancer is advancing and has now spread to Liver and Bones as brought out in his latest PET CT report. Lung tissue which was obtained during CT guided biopsy conducted in the month of Mar 17, before the CCRT treatment was started, has tested positive for EGFR mutation – “E746_A750del is detected in EXON 19 of EGFR gene”. The medicine oncologist has however said that the gene profiling of the primary tumour tissue is not sufficient for starting Targeted Therapy and gene profiling of a tissue obtained from any of the metastatic site is necessary for the same. Three procedures have been undertaken to obtain tissue sample from the metastases site, twice from the liver and once from the pleural deposits, and all the three times the cancerous tissue could not be obtained. Due to non-availability of conformed cancerous tissue from the metastases site, a firm treatment plan has yet not been made for my father. In the meantime, the doctor has recently started my father on Erlotinib 150 mg OD as there has been considerable delay in his next phase of treatment due to non availability of metastases cancerous tissue. Could you please help me by answering the following:- 1.Can you suggest anything towards treatment of my father? 2.Is gene profiling of tissue from a metastases site absolutely necessary for starting targeted therapy for my father? 3.I read online that Erlotinib or Afatinib can be used as Targeted Therapy for patient with EGFR Lung cancer mutation. Is this true? If yes, will a daily tablet of these drugs be sufficient for his next phase of treatment, or a concurrent conventional chemotherapy is also required? 4.Can 65 session of Hyper-basic Oxygen Therapy at 2.4 ata given at a stretch of about 80 days, with a daily dose of 02 hour be a cause of his cancer? I have read it online that the oxygen free radical produced during HBOT treatment can cause cancer.

MS, DNB (Surgical Oncology)
Oncologist, Jodhpur
Hi lybrate-user, You summarize the case very well. I understanding of your case says, he has Ca lung adenoca, treated with dCTRT, that progressed and now disseminated disease, which is not curable by any means. The goal of the treatment in such cases would be palliative only, which means to increase longevity without causing much side effects of the drugs and reduce his problem. Now going towards your questions, 1&2. At this juncture, Gene profiling is not necessary for me but to start the EGFR targeted medicines, which includes Erlotinib/Gefitinib or Afatinib. Usually patients with such mutation as in your case responded but unfortunately not for the indefinite period but averagely 6 to 10 months. On progression, you have to get the gene profiling to see the change in the mutational status. You can refer to NCCN guidelines or American cancer society information. 3. Your father should receive, targertd therapy only, no chemotherapy for sure. It is proven better than chemotherapy in terms of Quality of life and progression free survival (average duration to progress on Treatment) 4. Regarding etiology or causation of lung cancer, HBOT not implicated for such cancers. And more so any carcinogen if cause cancer, it has a reasonable time to show its effects, like you must have seen chronic (long term) smokers will develop lung cancer. HBOT cause local hypervascularization and produce free radicles, so many studies tried see its role as a carcinogen, but tilll date it is not proven carcinogen as per ICAR. Hoping it solves your query. It is nice to see a son is keen and read in-depth about his father's illness. Good luck for further treatment.
2 people found this helpful

Popular Health Tips

Benefits of Turmeric

Master in Psychology, MD - Ayurveda, Dems, Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Ayurveda, Ghaziabad
Benefits of Turmeric
Health benefits of turmeric

1. It is a natural antiseptic and antibacterial agent, useful in disinfecting cuts and burns.

2. When combined with cauliflower, it has shown to prevent prostate cancer and stop the growth of existing prostate cancer.

3. Prevented breast cancer from spreading to the lungs in mice.

4. May prevent melanoma and cause existing melanoma cells to commit suicide.

5. Reduces the risk of childhood leukemia.

6. Is a natural liver detoxifier.

7. May prevent and slow the progression of alzheimer's disease by removing amyloyd plaque buildup in the brain.

8. May prevent metastases from occurring in many different forms of cancer.

9. It is a potent natural anti-inflammatory that works as well as many anti-inflammatory drugs but without the side effects.

10. Has shown promise in slowing the progression of multiple sclerosis in mice.

11. Is a natural painkiller and cox-2 inhibitor.

12. May aid in fat metabolism and help in weight management.

13. Has long been used in Chinese medicine as a treatment for depression.

14. Because of its anti-inflammatory properties, it is a natural treatment for arthritis and rheumatoid arthritis.

15. Boosts the effects of chemo drug paclitaxel and reduces its side effects.

16. Promising studies are underway on the effects of turmeric on pancreatic cancer.

17. Studies are ongoing in the positive effects of turmeric on multiple myeloma.

18. Has been shown to stop the growth of new blood vessels in tumors.

19. Speeds up wound healing and assists in remodeling of damaged skin.

20. May help in the treatment of psoriasis and other inflammatory skin conditions.
7 people found this helpful

Table of Content

About Altaxel 300 MG Infusion
When is Altaxel 300 MG Infusion prescribed?
What are the contraindications of Altaxel 300 MG Infusion?
What are the side effects of Altaxel 300 MG Infusion?
Key highlights of Altaxel 300 MG Infusion
What are the substitutes for Altaxel 300 MG Infusion?
What are the dosage instructions?
Where is the Altaxel 300 MG Infusion approved?
What are the interactions for Altaxel 300 MG Infusion?