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Overview

Napilex 200 MG Syrup

Manufacturer :  Mankind Pharmaceuticals Ltd
Medicine Composition :  Sodium Valproate
Prescription vs OTC : Prescription by Doctor not required

About Napilex 200 MG Syrup

Napilex 200 MG Syrup, an anticonvulsant, helps in controlling seizures in patients who suffer from epilepsy. It effectively increases a certain type of brain chemical that control some seizures. This medication should be consumed orally and can be taken before or with a meal. It is generally advised that the drug should not be taken with carbonated drinks, as irritation in the throat may occur. The dosage of the drug depends on the patient’s age, health, weight and severity of the condition. In case you are taking Napilex 200 MG Syrup to control seizures do not stop it suddenly. It is advised that the drug should be discontinued gradually, so as to prevent any complications.

Napilex 200 MG Syrup use can lead to some side effects which include- dizziness, hair loss, tremor, diarrhea, changed in weight and blurred or double vision. These side effects stop gradually, but in case any of them continue or tend to worsen seek medical help immediately. A few patients may also experience mood swings and undergo depression resulting in suicidal thoughts. In case of overdosage, consult doctor immediately. Symptoms of over dosage can include coma, irregular heart rate and extreme drowsiness.

The allergic reaction to this drug may result in a rash or chest pain along with shortness of breath. Seek medical help in this case.

    What are the uses of Napilex 200 MG Syrup

    • Epilepsy

      Napilex 200 MG Syrup treats Epilepsy which is a brain disorder that causes repeated seizures. Uncontrolled jerking movements and loss of consciousness are some of the symptoms of Epilepsy.

    • Mania

      Napilex 200 MG Syrup helps in treating mania which is a mental disorder characterized by hyperactivity and racing thoughts.

    • Migraine Prophylaxis

      Napilex 200 MG Syrup is used as prophylaxis in migraine headaches characterized by severe headache, eye pain, nausea, and vomiting.

    What are the contraindications of Napilex 200 MG Syrup ?

    • Allergy

      Avoid this medication if you have a known allergy to Napilex 200 MG Syrup.

    • Liver Disease

      Do not take if you have any liver injury or a family history of liver injury.

    • Urea Cycle Disorders

      Do not use in patients with urea cycle disorder (high ammonium levels in the blood) or family history of urea cycle disorder.

    • Mitochondrial Disorders

      Do not use in patients and in children who are suspected to have the mitochondrial disorder (POLG e.g Alpers-Huttenlocher Syndrome).

    What are the side effects of Napilex 200 MG Syrup ?

    Key highlights of Napilex 200 MG Syrup

    • How long is the duration of effect?

      The effect of Napilex 200 MG Syruplasts for an average duration of 24 hours.

    • What is the onset of action?

      The peak effect of Napilex 200 MG Syrup can be observed in 2 hours.

    • Are there any pregnancy warnings?

      Napilex 200 MG Syrup is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      Breastfeeding women should not use this medication. Monitoring of undesired effects like discoloration of eyes and skin is necessary.

    What are the substitutes for Napilex 200 MG Syrup ?

    Below is the list of medicines, which have the same composition, strength and form as Napilex 200 MG Syrup , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Napilex 200 MG Syrup, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    How does this medication work?

    Napilex 200 MG Syrup belongs to the class anticonvulsants. it works by increasing the levels of neurotransmitter GABA and inhibits sodium and calcium channels thus it reduces the excitation of the brain cells.

      What are the interactions of Napilex 200 MG Syrup ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Alcohol

        Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Lamotrigine

        Napilex 200 MG Syrup may increase the concentration of lamotrigine and can cause serious skin reactions. Frequent monitoring of undesired effects like skin rash, seizures, tremors is necessary. Suitable dose adjustments or an alternate medicine should be considered based under the doctor's supervision.

        Metoclopramide

        Use of Napilex 200 MG Syrup with metoclopramide should be avoided if possible. Do not operate heavy machinery if you are using these medicines. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition under the doctor's supervision.

        Warfarin

        Napilex 200 MG Syrup should be given with caution in patients with warfarin or other anticoagulants as this combination may increase the risk of bleeding. Frequent monitoring of blood cells count and prothrombin time is necessary. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition under the doctor's supervision.

        Ethinyl Estradiol

        The desired effect of Napilex 200 MG Syrup will not be observed if taken with oral contraceptives. Inform the doctor if you are receiving either of the medications. Monitoring of behavior changes and seizures are necessary. An alternate medicine should be considered based on the clinical condition of the under the doctor's supervision.

        Imipenem

        Use of these medicines is not recommended as it increases the concentration of Napilex 200 MG Syrup. An alternate medicine should be considered based on the clinical condition under the doctor's supervision.
      • Interaction with Disease

        Depression

        Napilex 200 MG Syrup should be given with caution in the patients with depression and suicidal thoughts. Frequent monitoring of depression symptoms is necessary. Dose adjustments are to be made based on the outcomes in the patient.

        Liver Disease

        Napilex 200 MG Syrup is not recommended in patients with liver injury or a family history of liver injury. This risk is more in children less than 2 years of age. Liver function tests are to be performed before starting the treatment. Discontinue the medicine if any abnormality is identified.
      • Interaction with Food

        Food

        Information not available.
      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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