Fractional skin rejuvenation is a procedure executed by the cosmetologist who involves interaction with the skin to produce microthermal zones of injury and heat for treating areas on the skin. Intense beam of light is provided on the skin and it becomes hot to stimulate the cells for the production of collagen and elastin for improving the skin elasticity and overall appearance. The light also targets damaged blood vessels and age spots. The CO2 lasers are now more modern with latest technological advancements and have proven amazing results with significant enhancements and no downtime. The conventional resurfacing laser treatment would work on the entire skin surface however the latest fractional skin rejuvenation works only on the affected area of small portion on the skin that require treatment. The primary goal of the fractional skin rejuvenation treatment is to target only a fraction of the skin that requires treatment and by reducing the healing time and quicker recovery. In the fractional skin rejuvenation treatment there are no gels or no pain with the advanced procedures. The treatment will include only milder sensations or vibrations of heat. The results are visible within a week's time of process with enhancements in the skin texture, tone and pigmentation. More effective results of reduced fine lines are visible after more sessions of laser treatments. The fractional skin rejuvenation is the most preferred treatment suggested by dermatologists and cosmetologist worldwide as a cosmetic treatment to enhance and improve the damage caused to the skin due to aging and other reasons.