Vitiligo is a skin disorder where white patches of depigmentation develop on the skin and keep enlarging. This disorder is long term and continuous in nature. The patches appear due to the death of melanocytes within the skin. Melanocytes are skin pigment producing cells, which produce melanin. Vitiligo can affect the skin of several areas, including the eyes, hair and the portion inside the mouth.

Causes
The causes of this disease are as follows:
1. Autoimmune disorders in which the immune system of a patient becomes over reactive and the melanocytes are destroyed.
2. This disease may also occur due to genetic oxidative stress imbalance.
3. Stressful events may also lead to vitiligo.
4. Harm or damage to the skin from sunburns or cuts also leads to vitiligo.
5. Exposure of the skin to several harmful chemicals may be a cause.
6. Neural disorders are also responsible for vitiligo.
7. Vitiligo may also happen from viral causes or may be hereditary and passed on from family members.

Symptoms
Vitiligo has only one major symptom. White, flat spots and patches develop on the surface of the skin. The earliest of these white patches appear on the parts of the body which are exposed to the sun continuously.
It starts off as a simple spot in the beginning and gradually, the spot starts getting pale and finally turns white. The patches have irregular shapes, and in some cases the edges get inflamed and are red in color. Itchiness is experienced in the affected areas. Symmetrical patches signify slow development of vitiligo.

The two major types of vitiligo are:
1. Non segmental vitiligo, which affects the back of the hand, the arms, knees, elbows, feet, mouth.
2. Segmental vitiligo, which is more stable than non segmental vitiligo, but spreads faster. It usually affects areas of the skin, which are attached to nerves.

Treatment
The different methods of treatment for vitiligo are:
1. Phototherapy with UVB and UVA light: Exposing the affected area of the skin to UVB lamps is a popular cure for vitiligo. This treatment can be performed easily at home. UVA treatment incorporates taking of a drug which makes the skin more sensitive to ultraviolet light and then the skin is exposed to high doses of UVA light.
2. Skin Camouflage: Cosmetic creams and makeup can be used to camouflage affected areas of the skin. These topical creams are waterproof.
3. Depigmentation: Depigmentation is used to treat widespread areas affected by vitiligo. The skin color of the unaffected areas is reduced in order to match the affected areas. It is done using topical ointments.
Vitiligo is a skin disease, the major causes of which are still to be discovered. Proper care and treatment should be taken for skin areas affected by vitiligo.

Vitiligo: Causes, Symptoms and Treatments

Vitiligo is a disease which results in the loss of skin colouring pigment and ultimately the person loose his or her skin colour in blotches. The rate and to what extent the colour loss will happen is always unpredictable. When the Melanocytes cells lose their ability or get destroyed completely, the human skin starts losing it's skin colour produced by these Melanocyte cells. Vitiligo can generally affect skin present of any body part. Vitiligo is a common disease and it affects almost one million people every year all over the world. The disease can affect a person of any age.

Causes of Vitiligo

There are different causes due to which Vitiligo is caused. Let us have a look :

Vitiligo can happen due to an autoimmune disorder, when the immune system becomes overactive and results in the destruction of the colour pigment-producing cells i.e. the Melanocytes.
Vitiligo is also believed to affect people because of genetic factors. The immune system can get affected by the genes and results in a loss of skin colouring melanocytes. It can be hereditary and gets passed on. However, it is not at all contagious and cannot be passed on to someone else.
Harmful exposure to UV rays can cause the body to loose melanocyte cells. Heavy sunburn is also a common cause of the disease.
A stressful life schedule or oxidative stress imbalance can easily make the melanocyte cells to go weak and eventually wither away.
A foreign virus or bacteria which may enter into the immune system and if not destroyed affects the melanocytes in different parts of the body.
Treatment for Vitiligo-

Vitiligo Treatment or White Patches Treatment is based on improving your skin s appearance by restoring its colour. Re-pigmentation treatment is most successful on face and trunk; hands, feet and areas with white hair respond poorly. Compared to long-standing patches, new ones are more likely to respond to medical therapy.

The treatment can be classified into

Medical

Medicines applied to the skin, such as:
Corticosteroid creams or ointments
Immunomodulator creams or ointments, such as Elidel & Protopic
Topical drugs such as methoxsalen (Oxsoralen)
Oral Medical treatment includes the use of immune-modulating drugs such as systemic corticosteroids, levamisole, cyclophosphamide, azathioprine, vitamin supplements (especially vitamin B12 and folic acid).
Phototherapy NBUVB full body   A medical procedure in which your skin is exposed to ultraviolet A (UVA) or ultraviolet B (UVB) light from a special lamp in full body chambers.
Excimer (Targeted Phototherapy)   Targeted phototherapy, also called concentrated phototherapy, focused phototherapy and microphototherapy, involves delivery of ultraviolet radiation directly focused on, or targeted at, the skin lesion through special delivery mechanisms.
Surgical Procedures

Surgical treatment   Normal skin is used as donor tissue and then grafts are surgically transplanted on areas of Vitiligo treatment. The new skin grafts start producing pigment. Patients who are candidates for this procedure must have stable Vitiligo, or Vitiligo that has not changed for at least one year. The criteria of stability is taken as (a) no new White patches, (b) no extension of existing White patches and (c) no loss of pigmentation of previously repigmened patches for at least 1 year. This procedure can be used for patients with limited areas of Vitiligo and also in those with more extensive disease.
Melanocyte cell transplantation   In this procedure, a skin graft is taken from the patients own thigh, this skin is then treated with an enzyme known as trypsin which separates all the layers of the skin and thus Melanocytes and Keratinocytes are concentrated. The Vitiligo (Skin White Spot) skin is then removed with the use of diamond burs or Lasers and the cells are transplanted. The advantage of this procedure is that cell culture is not needed and that skin harvesting from the donor area, preparation of cell separation and application of Melanocytes can all be undertaken in a single 3-h procedure.
Blister Grafting   In this procedure, blisters are created on your pigmented skin primarily by using suction. The tops of the blisters are then cut out and transplanted to a depigmented skin area where a blister of equal size has been created and removed.
Punch grafting  Punch grafting is the simplest and the least expensive of all the grafting procedures in Vitiligo. The procedure involves the transfer of circular pieces or punches of skin tissue from the donor area into similar shaped pits that are made on the recipient skin. The size of these punches can range from 1 mm to 2 mm and they are spaced 5-10 mm apart on the recipient skin.
De-pigmentation  Depigmentation involves fading the rest of the skin on your body to match the already-white areas. If you have vitiligo on more than 50 percent of your body, depigmentation may be the best treatment option. In this procedure, the drug monobenzone (Benoquin) is applied twice a day to the pigmented areas of your skin until they match the already-depigmented areas. Some patients who are resistant to depigmentation with drug monobenzone (Benoquin) will need Q Switch NDYAG Laser to destroy the pigment cells. Depigmentation in most patients is a permanent technique in which the whole body is gradually turned white.
Color (Camouflage)   Camouflage used to treat vitiligo can be classified into two- temporary and permanent. 
Temporary colouring is the method which intends to blend the white patches with the rest of the body s colour. The method is done using coloured creams to the affected skin. Those creams will have the same shade as that of the natural skin. Applying the creams make the patches less noticeable.
Tattooing (permanent coloring)   Tattooing is injecting artificial pigment into the depigmented area. After selecting the pigment shade which matches the surrounding skin color, the pigment granules are implanted into the depigmented patch either with a manual or electrically driven needles. Though the patch resembles the surrounding normal skin, it may permanently fade or acquire a bluish hue after 1   2 years which is distinctly noticeable and may become unacceptable. Hence, tattooing is usually not advised unless the patch is in an inoperable site.

Best Vitiligo Treatment  - Medical & Surgical Methods

Vitiligo is a condition in which white patches appear on the skin. It can affect any part of the body. It can affect the inside of the mouth and the hair as well. It happens when the skin cells (melanocytes) that make or produce pigment (colour) of the skin die or stop functioning. This disease is not contagious or life-threatening, it cannot be caught from another person having vitiligo. All types of skin can be affected by vitiligo but it may be more evident in people with darker skin. It develops between the ages 10 to 30 and it often appears before the age of 40.

Causes

The main cause of this disorder is still not clear, why the cells die or fail. For some reason, the colour or pigment-forming cells called melanocytes dies. However, these are the following reasons that can cause this problem:

An autoimmune disorder, where the defences of the body turn on their own cells instead of attacking the germs that destroyed the melanocytes

A trigger or stressful events such as exposure to industrial chemicals, stress, or sunburn

Family history (heredity)

A neural cause

A virus

A genetic oxidative stress imbalance

Symptoms

The one and only symptom of this condition is the appearance of white patches or flat white spots on the skin. Those white patches are irregular in shape. They may stay the same for a while but may get bigger with time on different parts of the body. It generally affects body folds such as armpits, around body openings, or around moles. It can also affect hair and eyelids. It does not cause any irritation, dryness, discomfort, or soreness in the skin.

Treatment

There is no known way to cure or prevent the condition but the appearance of the affected skin can be improved with corticosteroid creams and cosmetics. The doctor can recommend melanocyte transplant surgery which includes a new needling micro-grafting technique. The surgery includes a split-thickness skin graft that is taken from the normal area. Later, it is cut into very small pieces in diameter ranging from 0.1 mm-0.3 mm. The local anesthesia is given to the recipient area to implant the micro-grafts into the dermis by using the needling technique. This new method of treating this condition delivers satisfactory and rapid pigmentation.

Takeaway

Vitiligo is a disorder in which flat white spots or patches appear and can affect any area of the body. It happens when the melanocytes die or stop functioning. The condition can be managed by cosmetics, corticosteroid creams, therapies, and surgeries. Out of all these methods, melanocyte transplant surgery is a new and effective technique to manage this disease. However, it is always advisable to consult a doctor before opting for any of these methods. 

Vitiligo - Its Causes, Symptoms And Treatments!

Vitiligo is a skin condition that causes loss of pigmentation of the skin. Melanocytes, the pigment cells, within the skin are destroyed. This causes these parts of the skin to lose color and turn pale. It might affect different parts of the body including the arms, legs, face and even genitalia. It can affect a person of any age, ethnicity or gender.

Causes
The exact cause of vitiligo is not definitively known. However, there are a number of risk factors that might contribute towards the condition. These include-

Autoimmune disorders- Vitiligo might be a result of an autoimmune disorder where the overactive immune system destroys the pigment cells of the skin.
Exposure to Chemicals- Exposure to certain chemicals can increase the risk of vitiligo by causing depigmentation.
Hereditary factors- There might be a genetic pre-disposition towards vitiligo. Though a person can exhibit symptoms of the condition at any age, it is most commonly found to manifest itself around the age of 20 years.
Symptoms
Vitiligo may start with a simple spot of pale skin but over time, this spot expands and turns paler until it is white in color. Irregular in shape, the edges of these spots may inflame and cause itchiness.

Treatment
The treatment of vitiligo will be determined by a number of factors such as the number and the extent of the white patches and where they are located. Vitiligo treatment includes cosmetic, medical and surgical methods.

Cosmetic Treatment- Cosmetic and skincare products such as sunscreens, dye or makeup can help relieve and hide signs of the condition.
Medical Treatment- Oral medication or medicated ointments may be prescribed to treat Vitiligo. Photochemotherapy which involves the use of PUVA rays to induce re-pigmentation may also be prescribed. If the condition has spread to a considerable extent then the physician might advise that the color from the remaining areas of the skin also be removed in order to match the affected areas.
Surgical Treatment- Surgical treatments are at times prescribed which involve skin grafting or tattooing. This is usually prescribed for those with small patches of affected areas.
With ongoing and extensive research being conducted on this skin condition, we will in the near future be able to both understand and treat it better.

Vitiligo - What Causes It and How Can It Be Treated?

If you see continual and long-term white patches of depigmentation on your skin, it could be vitiligo. Vitiligo is a condition that appears when melanocytes in your skin are no more alive. This bunch of cells is responsible for producing the melanin pigment that endows the skin with its colour as well as protects it from the harmful UV rays. The area which may be affected by this dermatological disease varies from person to person, and it can also affect the hair, mouth and eyes as well. In most cases, the vitiligo affected area stays discoloured for the rest of the patient s life.

Various types of vitiligo and their symptoms
Scientists have classified vitiligo into two types: segmental and non-segmental. The non-segmental vitiligo is the most common variant and 90 percent of vitiligo affected patients suffer from this kind of disorder. In this disease, the patches take place with little symmetry on both sides of the body. It can be further broken down into 5 sub-divisions.

Generalised vitiligo: It can occur at any part of the body without any rules, and this is by far the most common type.
Acrofacial vitiligo: It is mostly seen on the toes and fingers.
Mucosal vitiligo: In this condition, the discolouration normally takes place around the lips and mucous membranes.
Universal vitiligo: This is the rarest type of vitiligo where the whole body is covered in white patches.
Focal vitiligo: This is most commonly found in children. The children have white and scattered patches across the body.
Possible treatments for vitiligo

Though there are no treatments possible that will re-pigment your skin to its original colour, there are several remedies that aid in decreasing the visibility of white patches on the affected areas of the skin. Some of them include:

Phototherapy with UVB radiation: This is a common form of treatment where the affected area is exposed to UVB radiation and can be performed at home too. If you have large white spots across the body, it is important to have the treatment performed by an expert at any healthcare centre.
Phototherapy with UVA radiation: In this treatment, a drug is first administered for increasing skin s sensitivity to this radiation. Then the affected area of the skin is exposed to high doses of UVA radiation.
Skin camouflage: In mild cases of vitiligo, cosmetic creams and make-up can be used to camouflage the affected area. It can last for about 12- 18 hours when applied in proper techniques.
In case you are suffering from vitiligo, it is crucial to speak with an expert and opt for the best means to curb down the impact of vitiligo.

Vitiligo - Signs You Are Suffering From It!

Vitiligo is a condition wherein the affected person starts losing the color of the skin, resulting in white patches. It can affect people of any age, sex, class, race, and ethnicity. Though Vitiligo is a lifelong condition, it can be managed with proper care and treatment.

Understanding the problem 

Vitiligo is a skin disorder where certain areas of the skin start losing its normal pigment. The total area of the skin that can be affected by the disease may vary from one person to another. It may even affect the inner side of the mouth, eyes and in some cases, even the hair.

Vitiligo is a photosensitive skin disorder which means that the affected areas shall be more sensitive to the rays of the sun than the unaffected areas. It is very difficult to determine whether the patches will start spreading or not, and to what extent. It may take weeks to spread, or the patches may remain stable for months or even years together. The lighter patches become more visible in people with dark and sun-tanned skin.

Causes

The destruction of pigment-causing cells called the melanocytes cause Vitiligo. The exact cause of vitiligo remains unknown, some conditions that contribute to vitiligo are mentioned below:

Albinism: It is a rare genetic disorder that lead to loss of color of the skin, hair, and the eyes.
Alopecia Areata: It is an auto-immune disease that leads to hair loss in patches. It can also lead to vitiligo.
Hashimoto s thyroid: It is also an autoimmune disease that leads to discoloration of the skin. This also makes the skin more sensitive.
Symptoms

Patchy loss of skin color
Premature whitening or graying of the hair on your scalp, eyelashes, eyebrows or beard
Loss of color in the tissues that line the inside of your mouth and nose (mucous membranes)
Loss of or change in color of the inner layer of the eyeball (retina)
These white patches are more common in areas where the skin is exposed to the sun. The patches may be on the hands, feet, arms, face, and lips. Other common areas for white patches are:

The armpits and groin (where the leg meets the body)
Around the mouth
Eyes
Nostrils
Navel
Genitals
Rectal areas
Complications

If leaft untreated, patient can have an increased risk of:

Sunburn and skin cancer
Social or psychological distress
Hearing loss
Eye problems, such as inflammation of the iris (iritis)
Treating vitiligo
Vitiligo is described as more than a cosmetic problem; it is rather a health issue requiring clinical attention. Several remedies can aid in making the condition less visible, and some of them include:

Using sunscreen regularly: Using sunscreen protects the lighter areas of the skin which are more sensitive to sun rays. Since there are several types of sunscreen available, consulting with a dermatologist is safe before choosing a sunscreen.
Phototherapy using UVB light: Controlled exposure to UVB light is an effective treatment option for vitiligo. When this treatment is done at a clinic, you will need around 2 to 3 visits in a week, and the time required for the treatment will also be longer. UVB phototherapy can also be used when there are numerous white spots all over the body. Since this is a full-body treatment, it is performed in a hospital. This treatment, together with other treatments can have a substantial effect on vitiligo, but it is always necessary to have realistic expectations about the treatment.
Skin camouflage: Those who are suffering from mild instances of vitiligo can greatly benefit from the camouflage treatment done with cosmetic creams or white patches.
Laser therapy: People suffering from limited, stable patches of vitiligo can immensely benefit from vitiligo. Laser therapy is a safe and effective way to treat this condition. It may not be very cost effective, but the results are totally worth it, a patient may have to be treated twice a week and take 24-48 session to treat the localised lesions of vitiligo.
It is best to start the treatment of vitiligo as soon as possible to manage the condition to a substantial extent. So, visit a dermatologist today and understand which treatment option would work best for you.

Vitiligo - How Can The Condition Be Treated?

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