Pelizaeus-Merzbacher Disease is an inherited condition that impairs the proper functioning of the central nervous system. It is a part of a category of disorders termed as leukodystrophies. When myelin, the covering that secures the nerves and allows smooth transmission of nerve impulses begins to degenerate, leukodystrophies occur. Dysmyelination, i.e. the inability to produce myelin leads to Pelizaeus-Merzbacher Disease. This disease severely affects motor skills, obstructing normal movement and coordination. It also affects the patient’s intellectual abilities, such as abilities related to memory and language use. Although both of these are obstacles in the normal functioning of life, the disease has a more severe effect on the motor skills of the patient.
HOW IS PELIZAEUS-MERZBACHER DISEASE DIAGNOSED?
There is no known cure for this disease. The treatment that is offered is generally supportive and specific to certain symptoms of the disease.