Age 74 Brain injury 1 April 2013 Craniotomy then Cranioplasty Persistent vegetative state since then on 100% nursing care Tracheostomy Feed thru PEG Urine thru supra pubic catheter We have been changing spc every 15 days thru our nursing staff Today morning while inserting cath thru his spc opening there was lot of bleeding thru his normal urine route and also thru spc opening 20 ml approx. We removed spc and put condom cath. Water intake increased Now blood is still coming in urine bag but little like 3 ml to 4 ml along with urine No fever so far Shall we wait for fever to start and then give IV antibiotics or we can start now Can we send urine for culture now or post infection and fever starts. What antibiotics we can administer in case fever starts.