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Dear doctor we have a patient of schizophrenia having auditory hallucinations (female 34 year) and is taking clozapine 50 mg as prescribed by doctors of Aiims Delhi. Now that the third generation partial agonist are ready we want to shift her to cariprazine. You are requested to kindly reply if this new anti psychotic molecule makes permanent covalent bond with the receptors d2 and d3. Has it permanent effect and can cure the patient of schizophrenia. Please prescribe the dose so that we can arrange from online pharmacy. We will be highly obliged and thankful to you.
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To my knowledge Cariprazine is not still available in India for prescriptuon. Studies till now have shown its efficacy in negative symptoms but hallucinations are positive symptoms. Clozapine is effective if other drugs have failed. Till now there is no permanent cure for schizophrenia.
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