A 42 years women taking carbamazepine olanzapine and valproate since 2.5 months but now painful mouth sores occurred with slight face inflammation what is cause and what to do?

Question

Patient on chronic antiepileptic therapy tend to develop vit deficiency manifestations. Usually oral lesion can be due to plethora of reasons and maybe completely unrelated to antiepileptic therapy as such. But usually we give patients with antiepileptic medication a supplemental therapy of vit b12 and folic acid. Folic acid is more important with or without vit b12 to check homocysteine levels in thes patients. The dose and drug recommendation wrt antiepileptic therapy is best done with your treating physician. So I will advise you to supplement your child with folic acid with or without vit b12 and also consult your treating physician regarding the same.

Shamsul Haq · Accepted Answer

Patient on chronic antiepileptic therapy tend to develop vit deficiency manifestations. Usually oral lesion can be due to plethora of reasons and maybe completely unrelated to antiepileptic therapy as such. But usually we give patients with antiepileptic medication a supplemental therapy of vit b12 and folic acid. Folic acid is more important with or without vit b12 to check homocysteine levels in thes patients. The dose and drug recommendation wrt antiepileptic therapy is best done with your treating physician. So I will advise you to supplement your child with folic acid with or without vit b12 and also consult your treating physician regarding the same.