My wife is 56 years old, I am suffering from Migraine pain since long. After taking too much medicine of Allopathic (vasograin, ultracet, etc) and homeopathic Sanguinaria, spigelia, Nat mur, Nux Vom, gelsemium belladonna) but no improvement has shown. She is also suffering with diabetes, High blood pressure etc, she is too much sensitive of any change of weather and most of the ailments takes place in late night.