Hi mam, my last period was 18 days late and doctor told me this is due to the acne medicine isotrenion. Doctor suggested me regestrone 5 mg for 5 days and I got my period on 7 day. My last period date was 17 nov and lasted on 22 nov and flow was normal like period moreover I did 4 upt with prega news and found negative. But this month also I did not get my period till date and I have taken isotrenion for 5 days 8-12. So please help me is their any change of pregnancy.