Sir, I have been suffering from cholangio metastatic from last month, 02 cycles and day 1 chemotherapy already have taken. Now my physical condition is very week. I can't sit and walk. Always laid down on the bed constantly and result made bed sore. Last two days I can't talk easily due to mouth problems. I also used candid mouth gel. So, I request to you kindly advice me the chemotherapy is working or not. My hemoglobin percentage is decreasing. Sir, my problems will be solve or not. Kindly what I do.