Hi, I'm 55 years female from kolkata. I'm a diabetic (take Glycomet GP1 FORTE (GLIMEPIRIDE 1 mg + METFORMIN 1000 mg) twice & 10 iu insulin overnight ,fasting 80, PP 254 measured yesterday) & pancreatic (taking Panlipase 25000 after food thrice every day for last 5 years) patient. For the last 1 year, I'm feeling pain in fingers of both hands and in shoulder joints. Pain is unbearable at times. In afternoon often we see middle fingers of the hands get deformed. Visited a doctor. And he told this is a rheumatic arthritis. He gave Wysolone 10 mg for 45 days followed by wysolone 5 mg for 30 days. HCQ (Hydroxychloroquine) 300 mg, ARAVA (Leflunomide) 20 mg, INJ. Folitrax 20 mg once on sundays. Folvite 5 mg mondays to saturdays. Wysolone is now completely stopped. When I take wysolone there is no pain in fingers. Here is the test reports at a glance, Uric Acid 3.69 (range 2.6-6.0), RF 7.15 (<14), CRP 3.02 (<5) vit D (25 oh D) 36.12 (30 -100. AntiCCP Anti Body 5.61 (<20). CBC, Haemoglobin 11.8 gm/dl (range 12.5 - 15.3), MCHC (Mean corpuscular Hemoglobin concentration) 32.9 (range 33.4-35.5),Total RBC 4.0 million cells/cu mm (range 4.5-5.1), lymphocytes 52% (range 20-40) basophil 00 (range 01-02), ESR 16 (range <30) SGPT 13.8 U/L (range <35, Lipase 32.5 U/L (range 30-300), CRP 1.20 (range <10), amylase 78.2 (range 30 -110) Test was done in SERUM, Kolkata in 15th june 2017. Many doctors are telling me that this is rheumatic arthritis, But after 6 months of taking medicines for the same pain the still there, only fingers does not get deformed in afternoon. Please tell me is the diagnosis is right? Am I on right treatment? Or there is any other problem? Is there any bad action for taking panlipase 25000 for last 5 years? One more question for RA CRP & RF should be positive, but for my case it is negative, so how can it be RA?