Proline 1 MG Tablet

Proline 1 MG Tablet is primarily prescibed for the management of anxiety disorders or short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms.

Proline 1 MG Tablet falls under a class of psychoactive drugs known as benzodiazepine. It is given to people with anxiety disorders. It also used for sleeping disorder, seizures, surgery. Proline 1 MG Tablet is also used to treat acute coronary syndrome arising out of cocaine use.

On using Proline 1 MG Tablet the common side effects that you will experience are drowsiness, fatigue, low blood pressure and difficulty in breathing. For those of you already suffering from severe depression injecting this drug into your body may induce the increased desire for committing suicide. Therefore, close monitoring of such patients is advised.

In order to lower the chances of probable side effects, you should discuss with your doctor if you are or have:

• History of glaucoma.
• Pregnant, or are planning to become pregnant or are breastfeeding a baby.
• Alcoholic.
• Allergic to any of the ingredients contained within Proline 1 MG Tablet.
• History of depression.
• Seizures or epilepsy.
• Asthma or liver or kidney disease.
• Younger than 18 years of age.
• Taking any other medications.

The dosage for Proline 1 MG Tablet will be prescribed by your personal physician depending on your age, gender, medical history and the seriousness of your ailing condition. The recommended dosage in adults generally is about 2 to 3 mg orally about 2-3 times a day.

In case of IV injection, the dose is about 1-2 mg twice or thrice in a day. There should be equal intervals between doses. If you are taking it orally, have it with ample amounts of water. In case of a missed dose, take it as soon as possible, otherwise skip it. Do not double dose and in case of drug overdose, notify your doctor immediately.

Symptoms of Proline 1 MG Tablet overdose include confusion, coma, hypoactive reflexes, dyspnea, labored breathing. Treatment for benzodiazepine overdose is supportive. Rarely is mechanical ventilation required.

Flumazenil has been shown to selectively block the binding of benzodiazepines to CNS receptors, resulting in a reversal of benzodiazepine-induced CNS depression but not respiratory depression. Treatment requires support of blood pressure and respiration until drug effects subside.

Take exactly as directed (do not increase dose or frequency); may cause physical and/or psychological dependence. Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake).

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• Status Epilepticus

  Proline 1 MG Tablet is used in the treatment of status epilepticus which is a condition in which seizures present for a long time or a seizure follows immediately after another.

• Preanesthetic

  Proline 1 MG Tablet is used to relieve the symptoms of anxiety and tension in the patients undergoing surgical procedures.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• Allergy

  Not recommended in the patients with allergy to Proline 1 MG Tablet.

• Narrow Angle Glaucoma

  Not recommended in the patients with known case of narrow-angle glaucoma.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• Sedation

• Respiratory Depression

• Hypotension

• Confusion

• Dizziness

• Akathisia

• Unsteadiness

• Headache

• Depression

• Disorientation

• Dermatitis

• Rash

• Unexpected Weight Gain Or Loss

• Nausea

• Weakness

• Nasal Congestion

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 24 to 36 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed in 2 hours after an oral dose and 3 hours after an intramuscular injection.

• Are there any pregnancy warnings?

  This medicine is not recommended for pregnant women.

• Is it habit forming?

  Habit forming tendency has been reported

• Are there any breast-feeding warnings?

  This medicine is not recommended in breastfeeding women.

• Is It safe with alcohol?

  It is unsafe to consume alcohol with this medication.

• Is it safe to drive while on this medicine?

  It is unsafe to drive while you are taking this medication. As this medicine might affect the alertness of the patient.

• Does this affect kidney function?

  Caution must be taken in patients with kidney disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

• Does this affect liver function?

  Caution must be taken in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

Below is the list of medicines, which have the same composition, strength and form as Proline 1 MG Tablet , and hence can be used as its substitute.

• Larpose 1 MG Tablet

  Cipla Ltd

• Lopez 1 MG Tablet

  Intas Pharmaceuticals Ltd

• Lorvan 1 MG Tablet

  Cipla Ltd

• Nirsan 1 MG Tablet

  Glenmark Pharmaceuticals Ltd

• Norpose 1 MG Tablet

  Mankind Pharmaceuticals Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• Missed Dose instructions

  If you miss a dose of Proline 1 MG Tablet, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

This medication behaves as a type of Benzodiazepine drug which reduces nerve activity in the spinal cord and brain. It increases the effects of neurotransmitter gamma-aminobutyric acid which promotes relaxation by binding with the GABA receptors in the brain.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.

• Interaction with Lab Test

  This medication may increase the results of liver function tests

• Interaction with Medicine

  • Use with caution in elderly or debilitated patients, patients with hepatic disease (including alcoholics) or renal impairment. Use with caution in patients with respiratory disease or impaired gag reflex. Initial doses in elderly or debilitated patients should not exceed 2 mg. Prolonged lorazepam use may have a possible relationship to GI disease, including esophageal dilation.
  • Causes CNS depression (dose-related) resulting in sedation, dizziness, confusion, or ataxia which may impair physical and mental capabilities. Patients must be cautioned about performing tasks which require mental alertness (ie, operating machinery or driving). Use with caution in patients receiving other CNS depressants or psychoactive agents. Effects with other sedative drugs or ethanol may be potentiated. Benzodiazepines have been associated with falls and traumatic injury and should be used with extreme caution in patients who are at risk of these events (especially the elderly).
  • Lorazepam may cause anterograde amnesia. Paradoxical reactions, including hyperactive or aggressive behavior have been reported with benzodiazepines, particularly in adolescent/pediatric or psychiatric patients. Does not have analgesic, antidepressant, or antipsychotic properties.
  • Use caution in patients with depression, particularly if suicidal risk may be present. Use with caution in patients with a history of drug dependence. Benzodiazepines have been associated with dependence and acute withdrawal symptoms on discontinuation or reduction in dose. Acute withdrawal, including seizures, may be precipitated after administration of flumazenil to patients receiving long-term benzodiazepine therapy.
  • As a hypnotic agent, should be used only after evaluation of potential causes of sleep disturbance. Failure of sleep disturbance to resolve after 7-10 days may indicate psychiatric or medical illness. A worsening of insomnia or the emergence of new abnormalities of thought or behavior may represent unrecognized psychiatric or medical illness and requires immediate and careful evaluation.

• Interaction with Food

  Information not available.

• Interaction with Disease

  • Use with caution in elderly or debilitated patients, patients with hepatic disease (including alcoholics) or renal impairment. Use with caution in patients with respiratory disease or impaired gag reflex. Initial doses in elderly or debilitated patients should not exceed 2 mg. Prolonged lorazepam use may have a possible relationship to GI disease, including esophageal dilation.
  • Causes CNS depression (dose-related) resulting in sedation, dizziness, confusion, or ataxia which may impair physical and mental capabilities. Patients must be cautioned about performing tasks which require mental alertness (ie, operating machinery or driving). Use with caution in patients receiving other CNS depressants or psychoactive agents. Effects with other sedative drugs or ethanol may be potentiated. Benzodiazepines have been associated with falls and traumatic injury and should be used with extreme caution in patients who are at risk of these events (especially the elderly).
  • Lorazepam may cause anterograde amnesia. Paradoxical reactions, including hyperactive or aggressive behavior have been reported with benzodiazepines, particularly in adolescent/pediatric or psychiatric patients. Does not have analgesic, antidepressant, or antipsychotic properties.
  • Use caution in patients with depression, particularly if suicidal risk may be present. Use with caution in patients with a history of drug dependence. Benzodiazepines have been associated with dependence and acute withdrawal symptoms on discontinuation or reduction in dose. Acute withdrawal, including seizures, may be precipitated after administration of flumazenil to patients receiving long-term benzodiazepine therapy.
  • As a hypnotic agent, should be used only after evaluation of potential causes of sleep disturbance. Failure of sleep disturbance to resolve after 7-10 days may indicate psychiatric or medical illness. A worsening of insomnia or the emergence of new abnormalities of thought or behavior may represent unrecognized psychiatric or medical illness and requires immediate and careful evaluation.

• Ques : Is Proline 1 MG Tablet an opioid? Is it habit-forming medicine?

  Ans : No, this medication is not an opioid. Yes, it is a habit-forming medicine and can make a person physically and psychologically dependent.

• Ques : Can Proline 1 MG Tablet be used as a sleeping pill?

  Ans : Proline 1 MG Tablet is used for sleeping difficulties caused due to short-term anxiety.

• Ques : For how long will Proline 1 MG Tablet stay in my system?

  Ans : This drug may take around 3 days to get completely removed from the system.

• Ques : Are there any symptoms that I would experience if I get addicted to Proline 1 MG Tablet?

  Ans : You might feel unpleasant if you consume Proline 1 MG Tablet. Another symptom could be that you may increase the dose on your own to feel its effect.

• Ques : If I suddenly stop taking Proline 1 MG Tablet, will it affect me adversely?

  Ans : It is advised to reduce the dose of this drug gradually before completely stopping it. Suddenly stopping it may lead to withdrawal symptoms which include loss of the sense of reality, feeling detached from life, and unable to feel emotion.

• Ques : Does Proline 1 MG Tablet cause weight gain?

  Ans : The effect of Proline 1 MG Tablet on weight gain or loss is not known.

• Ques : Does Proline 1 MG Tablet cause depression?

  Ans : Yes, it might increase the risk of depression. This medication should be avoided by patients suffering from depression.

• Ques : Are there any harmful effects of taking more than the recommended doses of Proline 1 MG Tablet?

  Ans : Taking more than the recommended dose of this drug may cause loss of muscle control, low blood pressure, mental confusion, slow breathing, and even coma. It is advised to seek immediate medical help if you have consumed higher than the recommended dose.

• lorazepam-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 04 May 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/lorazepam

• lorazepam-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 04 May 2022].Available from:

  https://go.drugbank.com/drugs/DB00186

• LORAZEPAM injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 04 May 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=LORAZEPAM