Ibuprofen

Ibuprofen is prescribed for the management of pain and swelling. It is also used for treating inflammatory diseases and rheumatoid disorders including juvenile rheumatoid arthritis, mild to moderate pain, fever, dysmenorrhea, gout, ankylosing spondylitis and acute migraine headache.

This medicine belongs to the class of non-steroidal anti-inflammatory drugs. Ibuprofen works by altering the levels of hormones in the body to give relief from pain and inflammation.

The drug is suitable for adults as well as children who are 6 months and above. Ensure that you do not take Ibuprofen if-

• You have heart disease and are at a risk of suffering from a stroke or heart attack. Even those who do not have heart problems are likely to suffer a stroke or a heart attack because of prolonged use of Ibuprofen.
• You have recently had a bypass operation.
• You are allergic to any substance that is present in Ibuprofen.

This medication is not advisable for patients at the risk of cardiovascular diseases, recent bypass operation or with an allergy to the components of the medicine. It must also not be prescribed during the trimester of pregnancy and during breastfeeding.

Health conditions such as asthma, fluid retention, kidney problems, chronic ulcers, and bleeding, etc. also discourage the use of Ibuprofen. Get in touch with the doctor if you experience any of these-

• Signs of aseptic meningitis such as severe headache, high temperature, stiffness of the neck or intolerance to bright light.
• Signs of intestinal bleeding such as passing blood in your faeces (stools/motions), passing black tarry stools or vomiting any blood or dark particles that look like coffee grounds.

Ibuprofen can be prescribed to adults as well as children above 6 months. However, the dosage and duration vary according to the condition under treatment as well as the medical history of the patient. Doctor’s advice must be followed in this respect.

This medicine is useful against the following conditions:

• Pain Relief

• Juvenile Idiopathic Arthritis

• Mild To Moderate Pain

• Fever

• Dysmenorrhea

• Gout

• Ankylosing Spondylitis

• Acute Migraine Pain

• Allergy

  Not recommended in patients with known allergy to Ibuprofen or non-steroidal anti-inflammatory (NSAID) drugs

• Asthma

  Not recommended in patients with known conditions like asthma, rhinitis, and urticaria.

• Coronary Artery Bypass Surgery (Cabg)

  Not recommended in patients with recent heart surgery.

• Gastrointestinal Bleeding

  Not recommended in patients with peptic ulcer disease or any gastrointestinal bleeding disorders.

Below are some of the common side effects of ibuprofen:

• Dizziness

• Fatigue

• Rash

• Urticaria

• Abdominal Cramp

• Heartburn

• Indigestion

• Nausea

• Headache

• Nervousness

• Itching

• Fluid Retention

• Dyspepsia

• Vomiting

• Abdominal Pain

• Peptic Ulcer

• Gastrointestinal Bleeding

• Tinnitus

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 4 to 6 hours.

• What is the onset of action?

  The effect of this medicine can be observed in 30 to 60 minutes.

• Are there any pregnancy warnings?

  This medicine is not recommended for pregnant women.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is known to excreted through breast milk in small amounts. It is recommended in breastfeeding women.

• Does this affect kidney function?

  No relevant information is available. Consult a doctor before taking Ibuprofen.

• Does this affect liver function?

  Ibuprofen must be avoided in severe hepatic impairment.

• Missed Dose instructions

  The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for the next dose.

• Overdose instructions

  Seek emergency medical treatment or contact the doctor in case of overdose.

• India

• United States

• Japan

Below is the list of medicines, which contains Ibuprofen as ingredient

• Answell 400 Mg/325 Mg Tablet

  Cadila Pharmaceuticals Ltd

• Ibugesic 400Mg Tablet

  Cipla Ltd

• Combiflam Tablet

  Sanofi India Ltd

• Megadol Syrup

  Alembic Pharmaceuticals Ltd

• Imol Plus Tablet

  Zydus Cadila

• Maximol 400 Mg/325 Mg/100 Mg Tablet

  Croford Pharma Pvt Ltd

• Pyreflam 400 Mg/325 Mg Tablet

  Jawa Pharmaceuticals Pvt Ltd

• Bufex Kid 100 Mg/125 Mg Tablet

  Adcock Ingram Healthcare Pvt Ltd

• Magadol 100 Mg/125 Mg Syrup

  Alembic Pharmaceuticals Ltd

• Ibu P 100 Mg/162.5 Mg Suspension

  Indoco Remedies Ltd

Belonging to the class of NSAID, this medicine works by inhibiting the enzyme cyclo-oxygenase I and II. This leads to a decrease in the synthesis of prostaglandins that regulate fever, inflammation, pain and swelling.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

• Interaction with Alcohol

  This medicine should not be consumed with alcohol. Symptoms of stomach bleeding (such as the presence of dried and coffee colored blood in cough or stools) should be reported to the doctor immediately.

• Interaction with Lab Test

  Information not available.

• Interaction with Medicine

  Methotrexate

  Ibuprofen may increase the blood levels of methotrexate and can cause liver injury, breathing problem, and bleeding. Inform the doctor if you are receiving pain killers. The dose should be adjusted based on the clinical condition. Close monitoring of kidney function and blood cell count is necessary.

  Corticosteroids

  Use with caution as this combination will increase the risk of gastrointestinal bleeding. Inform the doctor if you are taking either of the medicines. Consider taking alternative medicine after consulting your doctor.

  Aspirin

  Ibuprofen may reduce the effect of aspirin and increases the risk of bleeding. Any symptoms like gastrointestinal bleeding, abdominal pain, blood in stools should be informed to the doctor. An alternate medicine should be considered based on the clinical condition.

  Antihypertensives

  If you are taking antihypertensives like furosemide and ramipril with Ibuprofen, then you are at increased risk of kidney damage. This interaction is more likely to happen in the elderly population. Regular monitoring of kidney function is necessary. The dose should be adjusted based on the clinical condition.

• Interaction with Disease

  Asthma

  Ibuprofen should not be taken if you have NSAID-sensitive asthma. Any such history should be reported to the doctor so that appropriate substitution can be done.

  Fluid Retention And Edema

  Ibuprofen should be taken only after consulting a doctor. Monitoring of blood pressure and heart conditions is necessary on a regular level during the course of therapy.

  Skin Rash

  Ibuprofen can cause these fatal skin allergies without any warnings. Signs and symptoms like rashes, hives, fever or other allergic symptoms should be reported without any delay. This condition requires immediate medical intervention.

• Interaction with Food

  Information not available.