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Prescription vs.OTC: Prescription by Doctor required
Last Updated: August 11, 2021

Ibuprofen is prescribed for the management of pain and swelling. It is also used for treating inflammatory diseases and rheumatoid disorders including juvenile rheumatoid arthritis, mild to moderate pain, fever, dysmenorrhea, gout, ankylosing spondylitis and acute migraine headache.

This medicine belongs to the class of non-steroidal anti-inflammatory drugs. Ibuprofen works by altering the levels of hormones in the body to give relief from pain and inflammation.

The drug is suitable for adults as well as children who are 6 months and above. Ensure that you do not take Ibuprofen if-

  • You have heart disease and are at a risk of suffering from a stroke or heart attack. Even those who do not have heart problems are likely to suffer a stroke or a heart attack because of prolonged use of Ibuprofen.
  • You have recently had a bypass operation.
  • You are allergic to any substance that is present in Ibuprofen.

This medication is not advisable for patients at the risk of cardiovascular diseases, recent bypass operation or with an allergy to the components of the medicine. It must also not be prescribed during the trimester of pregnancy and during breastfeeding.

Health conditions such as asthma, fluid retention, kidney problems, chronic ulcers, and bleeding, etc. also discourage the use of Ibuprofen. Get in touch with the doctor if you experience any of these-

  • Signs of aseptic meningitis such as severe headache, high temperature, stiffness of the neck or intolerance to bright light.
  • Signs of intestinal bleeding such as passing blood in your faeces (stools/motions), passing black tarry stools or vomiting any blood or dark particles that look like coffee grounds.

Ibuprofen can be prescribed to adults as well as children above 6 months. However, the dosage and duration vary according to the condition under treatment as well as the medical history of the patient. Doctor’s advice must be followed in this respect.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

This medicine is useful against the following conditions:

  • Allergy

    Not recommended in patients with known allergy to Ibuprofen or non-steroidal anti-inflammatory (NSAID) drugs
  • Asthma

    Not recommended in patients with known conditions like asthma, rhinitis, and urticaria.
  • Coronary Artery Bypass Surgery (Cabg)

    Not recommended in patients with recent heart surgery.
  • Gastrointestinal Bleeding

    Not recommended in patients with peptic ulcer disease or any gastrointestinal bleeding disorders.

Below are some of the common side effects of ibuprofen:

  • How long is the duration of effect?

    The effect of this medicine lasts for an average duration of 4 to 6 hours.
  • What is the onset of action?

    The effect of this medicine can be observed in 30 to 60 minutes.
  • Are there any pregnancy warnings?

    This medicine is not recommended for pregnant women.
  • Is it habit forming?

    No habit forming tendencies were reported.
  • Are there any breast-feeding warnings?

    This medicine is known to excreted through breast milk in small amounts. It is recommended in breastfeeding women.
  • Does this affect kidney function?

    No relevant information is available. Consult a doctor before taking Ibuprofen.
  • Does this affect liver function?

    Ibuprofen must be avoided in severe hepatic impairment.
  • Is It safe with alcohol?

    Consumption of alcohol must be avoided while taking Ibuprofen.
  • Is it safe to drive while on this medicine?

    Ibuprofen usually does not affect the consciousness of the patient, hence the ability of driving.
  • Missed Dose instructions

    The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for the next dose.
  • Overdose instructions

    Seek emergency medical treatment or contact the doctor in case of overdose.
  • India

  • United States

  • Japan

Below is the list of medicines, which contains Ibuprofen as ingredient

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Belonging to the class of NSAID, this medicine works by inhibiting the enzyme cyclo-oxygenase I and II. This leads to a decrease in the synthesis of prostaglandins that regulate fever, inflammation, pain and swelling.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    This medicine should not be consumed with alcohol. Symptoms of stomach bleeding (such as the presence of dried and coffee colored blood in cough or stools) should be reported to the doctor immediately.
  • Interaction with Lab Test

    Information not available.
  • Interaction with Medicine


    Ibuprofen may increase the blood levels of methotrexate and can cause liver injury, breathing problem, and bleeding. Inform the doctor if you are receiving pain killers. The dose should be adjusted based on the clinical condition. Close monitoring of kidney function and blood cell count is necessary.


    Use with caution as this combination will increase the risk of gastrointestinal bleeding. Inform the doctor if you are taking either of the medicines. Consider taking alternative medicine after consulting your doctor.


    Ibuprofen may reduce the effect of aspirin and increases the risk of bleeding. Any symptoms like gastrointestinal bleeding, abdominal pain, blood in stools should be informed to the doctor. An alternate medicine should be considered based on the clinical condition.


    If you are taking antihypertensives like furosemide and ramipril with Ibuprofen, then you are at increased risk of kidney damage. This interaction is more likely to happen in the elderly population. Regular monitoring of kidney function is necessary. The dose should be adjusted based on the clinical condition.
  • Interaction with Disease


    Ibuprofen should not be taken if you have NSAID-sensitive asthma. Any such history should be reported to the doctor so that appropriate substitution can be done.

    Fluid Retention And Edema

    Ibuprofen should be taken only after consulting a doctor. Monitoring of blood pressure and heart conditions is necessary on a regular level during the course of therapy.

    Skin Rash

    Ibuprofen can cause these fatal skin allergies without any warnings. Signs and symptoms like rashes, hives, fever or other allergic symptoms should be reported without any delay. This condition requires immediate medical intervention.
  • Interaction with Food

    Information not available.

Ques: What is Ibuprofen?

Ans: This medication contains Ibuprofen as an active ingredient in it. It controls the hormone responsible for the cause of pain and inflammation in the body. Thus provides relief from several problems like toothache, headache, arthritis, pain in the back, other types of small injuries and menstrual cramps.

Ques: How long do I need to use Ibuprofen before I see improvement in my condition?

Ans: This medication is to be taken till the time you see an improvement in your health conditions.

Ques: At what frequency do I need to use Ibuprofen?

Ans: This medication should be taken in the dosage as prescribed by the doctor.

Ques: Should I use Ibuprofen empty stomach, before food or after food?

Ans: This medication should be taken after food in a prescribed dosage.

Ques: What are the instructions for the storage and disposal of Ibuprofen?

Ans: This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

Ques: Does Ibuprofen cause blood in urine?

Ans: Yes, this medication can cause hematuria (blood in the urine), therefore, it is advised to not use this medication unless prescribed by your doctor.

Ques: Is Ibuprofen a Nonsteroidal Anti-inflammatory Drug?

Ans: Yes, this medication is an anti-inflammatory drug from the class called nonsteroidal anti-inflammatory drugs (NSAID). It works by reducing hormones that cause inflammation and pain in the body.

Ques: Can I take Ibuprofen with Tamsulosin or paracetamol?

Ans: Yes, this medication can be taken with Tamsulosin or paracetamol. No harmful side effects or other interactions have been seen when they are taken together.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Ibuprofen
What are the uses of Ibuprofen
What are the contraindications of Ibuprofen ?
What are the side effects of Ibuprofen ?
Key highlights of Ibuprofen
What are the dosage instructions?
Where is the Ibuprofen approved?
Medicines containing Ibuprofen
How does this medication work?
What are the interactions of Ibuprofen ?
FAQs about Ibuprofen