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Brufen 400Mg Tablet

Manufacturer: Abbott India Ltd
Medicine composition: Ibuprofen
Prescription vs.OTC: Prescription by Doctor not required

Brufen 400Mg Tablet is prescribed for the management of pain and swelling. It is also used for treating inflammatory diseases and rheumatoid disorders including juvenile rheumatoid arthritis, mild to moderate pain, fever, dysmenorrhea, gout, ankylosing spondylitis and acute migraine headache.

This medicine belongs to the class of non-steroidal anti-inflammatory drugs. Brufen 400Mg Tablet works by altering the levels of hormones in the body to give relief from pain and inflammation.

Get in touch with the doctor if you experience any of these-

  • Signs of aseptic meningitis such as severe headache, high temperature, stiffness of the neck or intolerance to bright light.
  • Signs of intestinal bleeding such as passing blood in your faeces (stools/motions), passing black tarry stools or vomiting any blood or dark particles that look like coffee grounds.

Brufen 400Mg Tablet can be prescribed to adults as well as children above 6 months. However, the dosage and duration vary according to the condition under treatment as well as the medical history of the patient. Doctor’s advice must be followed in this respect.

This medication is not advisable for patients at the risk of cardiovascular diseases, recent bypass operation or with an allergy to the components of the medicine. It must also not be prescribed during the trimester of pregnancy and during breastfeeding.

Health conditions such as asthma, fluid retention, kidney problems, chronic ulcers, and bleeding, etc. also discourage the use of Brufen 400Mg Tablet.

Brufen 400Mg Tablet is helpful in treating the below provided problems:

  • Allergy

  • Coronary Artery Bypass Surgery (Cabg)

  • Asthma

  • Peptic Ulcer

Common side effects of Brufen 400Mg Tablet are as follows:

  • How long is the duration of effect?

    The action of Brufen 400Mg Tablet lasts for 4 hours to 6 hours.

  • What is the onset of action?

    The effect of Brufen 400Mg Tablet starts within half an hour to one hour of consumption.

  • Are there any pregnancy warnings?

    Brufen 400Mg Tablet is unsafe during pregnancy, especially during the third trimester, as it can harm the foetus.

  • Is it habit forming?

    Brufen 400Mg Tablet is not habit forming.

  • Are there any breast-feeding warnings?

    This medication is unsafe for the baby during breastfeeding.

  • Is It safe with alcohol?

    Brufen 400Mg Tablet can result in blood in a cough and stools when consumed with alcohol.

  • Is it safe to drive while on this medicine?

    It is safe to drive while using Brufen 400Mg Tablet.

  • Does this affect kidney function?

    Brufen 400Mg Tablet affects renal function.

  • Does this affect liver function?

    Brufen 400Mg Tablet must be avoided in severe hepatic impairment.

  • Are there any missed dose instructions?

    Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.
  • Are there any overdose instructions?

    If overdose of Brufen 400Mg Tablet results in serious side effects, inform the physician.

Brufen 400Mg Tablet is a nonsteroidal anti-inflammatory drug that works by inhibiting the enzymes cyclo-oxygenase I and II. This leads to a decrease in the synthesis of prostaglandins that regulate fever, inflammation, pain and swelling.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Brufen 400Mg Tablet interacts with alcohol and is not safe for consumption with alcohol.

  • Interaction with Medicine

    Brufen 400Mg Tablet must not be prescribed along with medicines like Digoxin, Methotrexate, Corticosteroids, Aspirin and Antihypertensive.

  • Interaction with Disease

    Brufen 400Mg Tablet interacts with diseases like asthma, oedema and existing dermatological disorders like skin rashes. It may also result in fluid retention. Use must be taken in patients with congestive heart failure, dehydration, hypertension, decreased renal or hepatic function, history of GI disease (bleeding or ulcers).

  • Interaction with Food


    Brufen 400Mg Tablet May decrease the rate but not the extent of oral absorption; drug may cause GI upset, bleeding, ulceration, perforation. Take this medicine with food or milk to minimize GI upset.

Ques: What is Brufen 400Mg Tablet?

Ans: Brufen 400Mg Tablet is used to relieve pain in conditions like Osteoarthritis, Rheumatoid Arthritis. It is also used to treat mild to moderate fever. It contains Ibuprofen as an active ingredient. Brufen 400Mg Tablet works by reducing the activity of a chemical in the body that causes pain and swelling.

Ques: What are the uses of Brufen 400Mg Tablet?

Ans: Brufen 400Mg Tablet is used for the treatment and prevention from conditions and symptoms of diseases like dysmenorrhea, osteoarthritis, rheumatoid arthritis, and fever and pain. The patient should inform the doctor about any ongoing medications and treatment before using Brufen 400Mg Tablet to avoid undesirable effects.

Ques: What are the Side Effects of Brufen 400Mg Tablet?

Ans: This is a list of possible side-effects that may occur due to the constituting ingredients of Brufen 400Mg Tablet. This is not a comprehensive list. These side-effects have been observed and not necessarily occur. Some of these side-effects may be serious. These include acidic or sour stomach, heartburn, nausea and vomiting, abdominal discomfort, and constipation. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

Ques: What are the instructions for storage and disposal Brufen 400Mg Tablet?

Ans: Brufen 400Mg Tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. A doctor should be consulted regarding the dosage of Brufen 400Mg Tablet. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

Ques: How long do I need to use Brufen 400Mg Tablet before I see improvement of my conditions?

Ans: Brufen 400Mg Tablet is a medicine which takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients. There are numerous elements to consider such as, salt interactions, precautions to be taken care of, time is taken by the salt to performs its action, etc. we beg you to visit your doctor to realize to what extent before you can see improvements in your health while at the same time taking Brufen 400Mg Tablet.

Ques: What are the contraindications to Brufen 400Mg Tablet?

Ans: Contraindication to Brufen 400Mg Tablet. In addition, Brufen 400Mg Tablet should not be used if you have the following conditions such as weakness, slurring of speech, chest pain, shortness of breath, etc.

Ques: Is Brufen 400Mg Tablet safe to use when pregnant?

Ans: This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. The benefits from use in pregnant women may be acceptable despite the risk but there is no data available regarding the effect of Brufen 400Mg Tablet during pregnancy.

Ques: Will Brufen 400Mg Tablet be more effective if taken in more than the recommended dose?

Ans: No, taking higher than the recommended dose of Brufen 400Mg Tablet can lead to increased chances of side effects such as diarrhea, fatigue, gas, headache, nausea, skin rashes, vomiting, etc. If you are observing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Brufen 400Mg Tablet
What are the uses of Brufen 400Mg Tablet
What are the contraindications of Brufen 400Mg Tablet ?
What are the side effects of Brufen 400Mg Tablet ?
Key highlights of Brufen 400Mg Tablet
What are the dosage instructions?
How does this medication work?
What are the interactions of Brufen 400Mg Tablet ?
FAQs about Brufen 400Mg Tablet