Grisovin Fp 500 MG Tablet

Manufacturer: Glaxosmithkline Pharmaceuticals Ltd
Medicine composition: Griseofulvin
Prescription vs OTC: Prescription by Doctor required

Grisovin Fp 500 MG Tablet is an antifungal medication used to cure fungal infections of the hair, skin and nails. Grisovin Fp 500 MG Tablet works by not only preventing the fungal infection from spreading to new cells but also arrests the infection causing fungus from multiplying.

The common side effects that come with taking this drug include skin rashes, nausea, heartburn, diarrhea, dizziness, clouded thoughts, headache, signs of insomnia and numbness in various parts of the body. If these effects keep on persisting with no signs of leaving, then seek help from your doctor immediately.

This drug can cause serious effects which can prove to be fatal in the long run. These serious reactions comprise of swelling, fever, blisters, marked decrease in appetite, joint pain and constant feelings of fatigue. Should such an instance occur seek help immediately.

Certain conditions under which it is advised that you should refrain from taking this drug, if you have or are:

  • Allergic to the medication.
  • A history of porphyria or liver failure.
  • A history of lupus.
  • Pregnant, are planning to become pregnant or are breastfeeding.
  • Under any kind of medications, be it prescriptive or non-prescriptive and herbal.
  • Ensure not to conceive while you are taking this drug and also for at least six months after stopping it.
  • Taking hormonal pills as contraception.

The recommended dose for adults ranges between 500-1000 mg every day. Children are prescribed a low-power dose of about 125 mg depending on the height, weight and overall health. Make sure to take this drug only after you have had some food whether it is your full-fledged meal or a light snack.

Food substance in your stomach helps to absorb this drug better. In case of a missed dose, take it as soon as you recall it. If it is too late and already time for your next dose, do not overdose, skip the previous missed one entirely. In case of an instance of drug overdose contact your physician right away.

Take as directed; around-the-clock with food. Take full course of medication; do not discontinue without notifying your prescriber. Avoid alcohol while taking this drug (disulfiram reactions). Symptoms of overdose include lethargy, vertigo, blurred vision, nausea, vomiting, diarrhea.

Practice good hygiene measures to prevent reinfection. Frequent blood tests may be required with prolonged therapy. Report skin rash, respiratory difficulty, CNS changes (confusion, dizziness, acute headache), changes in color of stool or urine, white plaques in mouth, or worsening of condition.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

The most common use of this medication is:

  • Fungal Infections (Tinea Strains)

    This medicine is used for the treatment of fungal infections of the scalp, hair, skin, toenails, crotch, thighs, skin caused by tinea strains of fungi.

Here are some of the possible side effects of this drug:

  • How long is the duration of effect?

    The effect of this medicine lasts for an average duration of 2 days.
  • What is the onset of action?

    The effect of this medicine can be observed within 4-5 hours of oral administration.
  • Are there any pregnancy warnings?

    Use of this medicine by pregnant women is not recommended unless absolutely necessary. Consult your doctor before taking this medicine.
  • Is it habit forming?

    No habit forming tendencies were reported.
  • Are there any breast-feeding warnings?

    Use of this medicine by women who are breastfeeding is not recommended. Your doctor may prescribe a safer alternative if needed.
  • Is It safe with alcohol?

    Consumption of alcohol is found to be unsafe while taking this medicine.
  • Is it safe to drive while on this medicine?

    This medicine might affect the alertness of the patient, thus driving must be avoided while taking this medicine.
  • Does this affect kidney function?

    This medicine is probably safe to be used in patients with kidney disease. Available limited data suggests that adjustment of dose is not required. Kindly consult your doctor before taking it.
  • Does this affect liver function?

    Caution must be taken in patient with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as Grisovin Fp 500 MG Tablet , and hence can be used as its substitute.

  • Missed Dose instructions

    Take the missed dose as soon as you remember. The missed dose can be skipped if the next scheduled dose is less than two hours away.
  • Are there any overdose instructions?

    Contact your doctor immediately if an overdose with this medicine is suspected.
  • India

  • United States

  • Japan

This medication works by inhibiting fungal cell wall division by disrupting the mitotic spindle structure and also interferes with DNA production. It binds to keratin present in human skin and provides temporary resistance to fungal infections.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Avoid or minimize the use of alcohol while taking this medicine. Any side effects experienced should be reported to the doctor on priority.
  • Interaction with Lab Test

    False-positive urinary VMA levels.
  • Interaction with Medicine

    • Decreased effect:
      • Barbiturates may decrease levels of griseofulvin
      • Decreased warfarin, cyclosporine, and salicylate activity with griseofulvin
      • Griseofulvin decreases oral contraceptive effectiveness
    • Increased toxicity: With alcohol tachycardia and flushing
  • Interaction with Food

    Enhanced absorption with high fat meals; for enhanced absorption, should be administered with high fat meal; alcohol will cause "disulfiram"-type reaction consisting of flushing, headache, nausea, and in some patients, vomiting and chest and/or abdominal pain.
  • Interaction with Disease

    Safe use in children <2 years of age has not been established; during long-term therapy, periodic assessment of hepatic, renal, and hematopoietic functions should be performed; may cause fetal harm when administered to pregnant women; avoid exposure to intense sunlight to prevent photosensitivity reactions; hypersensitivity cross reaction between penicillins and griseofulvin is possible

Ques: What if I forget to take a dose of Grisovin Fp 500 MG Tablet?

Ans: If you forget a dose of Grisovin Fp 500 MG Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Ques: Is Grisovin Fp 500 MG Tablet effective?

Ans: Grisovin Fp 500 MG Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition.

Ques: Is Grisovin Fp 500 MG Tablet a steroid?

Ans: No, Grisovin Fp 500 MG Tablet is not a steroid. It is a medicine which is used to kill a wide variety of infection-causing fungus. It is applied on the affected skin or nails to treat fungal infections of the skin and nails.

Ques: Can Grisovin Fp 500 MG Tablet cause any local reaction or rashes?

Ans: Yes, the use of Grisovin Fp 500 MG Tablet may cause allergic reactions, but the probability is unknown. Such allergic reaction is not very common and is likely to occur in only susceptible or sensitive individuals. Immediately contact your doctor if you experience such reactions.

Ques: Is Grisovin Fp 500 MG Tablet safe?

Ans: Yes, the medication is safe, if used in the dose and duration advised by your doctor.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Grisovin Fp 500 MG Tablet
What are the uses of Grisovin Fp 500 MG Tablet
What are the contraindications of Grisovin Fp 500 MG Tablet ?
What are the side effects of Grisovin Fp 500 MG Tablet ?
Key highlights of Grisovin Fp 500 MG Tablet
What are the substitutes for Grisovin Fp 500 MG Tablet ?
What are the dosage instructions?
Where is the Grisovin Fp 500 MG Tablet approved?
How does this medication work?
What are the interactions of Grisovin Fp 500 MG Tablet ?
FAQs about Grisovin Fp 500 MG Tablet