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Overview

Grisoral 250 MG Tablet

Grisoral 250 MG Tablet

Manufacturer: Micro Labs Ltd
Medicine composition: Griseofulvin
Prescription vs.OTC: Prescription by Doctor required

Grisoral 250 MG Tablet is an antifungal medication used to cure fungal infections of the hair, skin and nails. The oral tablet is available both as a generic and brand name medication in all pharmacies. The liquid suspension however, is only available as a generic drug. And the brand name Gris-PEG comes in both liquid and tablet form. Grisoral 250 MG Tablet works by not only preventing the fungal infection from spreading to new cells but also arrests the infection causing fungus from multiplying.

The common side effects that come with taking this drug include skin rashes, nausea, heartburn, diarrhea, dizziness, clouded thoughts, headache, signs of insomnia and numbness in various parts of the body. If these effects keep on persisting with no signs of leaving, then seek help from your doctor immediately. This drug can cause serious effects which can prove to be fatal in the long run. These serious reactions comprise of swelling, fever, blisters, marked decrease in appetite, joint pain and constant feelings of fatigue. Should such an instance occur seek help immediately. Certain conditions under which it is advised that you should refrain from taking this drug are:

  • If you are allergic to the medication.
  • If you have a history of porphyria or liver failure.
  • If you have a history of lupus.
  • If you are pregnant, are planning to become pregnant or are breastfeeding.
  • If you are under any kind of medications, be it prescriptive or non-prescriptive and herbal.
  • Ensure not to conceive while you are taking this drug and also for at least six months after stopping it.
  • If you are taking hormonal pills as contraception.

The recommended dose for adults ranges between 500-1000 mg every day. Children are prescribed a low-power dose of about 125 mg depending on the height, weight and overall health. Make sure to take this drug only after you have had some food whether it is your full-fledged meal or a light snack. Food substance in your stomach helps to absorb this drug better. In case of a missed dose, take it as soon as you recall it. If it is too late and already time for your next dose, do not overdose, skip the previous missed one entirely. In case of an instance of drug overdose contact your physician right away.

Fungal infections (Tinea strains)
This medicine is used for the treatment of fungal infections of the scalp, hair, skin, toenails, crotch, thighs, skin caused by tinea strains of fungi.
This medicine is not recommended for use if you have a known history of allergy to Grisoral 250 MG Tablet or any other ingredient present with it.
This medicine is not recommended for use in patients having this this hereditary disease of the blood and skin.
Impaired Liver function
This medicine is not recommended for use in patients having an impairment of liver function or have severe liver damage.
In addition to its intended effect, Grisoral 250 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Skin rash and peeling Major Rare
Mouth Sores Moderate Less Common
Sore Throat Moderate Less Common
Headache Moderate Less Common
Diarrhea Moderate Less Common
Increased thirst Minor Common
Dizziness and fainting Moderate Less Common
Unusual tiredness and weakness Moderate Rare
Black or Tarry stools Major Rare
Cloudy urine Major Rare
Chest pain and discomfort Minor Less Common
Trouble Sleeping Minor Common
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 2 days.
What is the onset of action?
The effect of this medicine can be observed within 4-5 hours of oral administration.
Are there any pregnancy warnings?
Use of this medicine by pregnant women is not recommended unless absolutely necessary. Consult your doctor before taking this medicine.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
Use of this medicine by women who are breastfeeding is not recommended. Your doctor may prescribe a safer alternative if needed.
Below is the list of medicines, which have the same composition, strength and form as Grisoral 250 MG Tablet, and hence can be used as its substitute.
Glaxosmithkline Pharmaceuticals Ltd
Dr. Reddys Laboratories Ltd
Glaxosmithkline Pharmaceuticals Ltd
Glaxosmithkline Pharmaceuticals Ltd
Glaxosmithkline Pharmaceuticals Ltd
Missed Dose instructions
Take the missed dose as soon as you remember. The missed dose can be skipped if the next scheduled dose is less than two hours away.
Overdose instructions
Contact your doctor immediately if an overdose with this medicine is suspected.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Disease
Information not available.
Interaction with Alcohol
Ethanol Moderate
Avoid or minimize the use of alcohol while taking this medicine. Any side effects experienced should be reported to the doctor on priority.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Ketoconazole Moderate
Report the use of either of the medicine to the doctor. The risk of adverse effects is higher when these medicines are used together. Your doctor may determine the best course of treatment in such cases.
Warfarin Moderate
Report the use of either of the medicine to the doctor. Your doctor may advise certain specific blood test to determine the right dose. Suitable dose adjustment and frequent monitoring is advised if these medicines are to be used together.
Ethinyl Estradiol Major
Report the use of ethinyl estradiol or any other hormonal medicine to the doctor. The effect of the hormonal preparations may get reduced and result in failure of contraception. Your doctor may determine the best course of treatment after accessing the condition.
Atorvastatin Moderate
Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring while using these medicines together.
Sildenafil Moderate
Report the use of either of the medicine to the doctor. The efficacy of sildenafil may reduce while using it together with griseofulvin. Your doctor may prescribe an alternate medicine or make suitable dose adjustment to ensure safe and effective use of these medicines.

Popular Questions & Answers

Sir I am suffering from jock itch and ringworm on other body parts from last 5-6 months. I have been given fluconazole for 3 months, then griseofulvin 1000 mg for 2 months and currently now I am on Terbinafine 500 mg daily for about 5 days. Side by side I am also applying clotrimazole cream for 3 months. Although the redness and rings are reducing but it is very itching at the fungus locations. I am using LC-Z 10 but it is not helping. The continuous itching is very irritating as well as with burning sensation.

MBBS, MD - Dermatology , Venereology & Leprosy
Dermatologist, Mumbai
You are suffering from tinea cruris which is fungal infection of the inner thighs and genital area. It can be treated by taking four to six weeks of anti fungal treatment which includes tablets along with creams. Do not use soap over that area. I don't think even terbinafine a works these days. Other option are there. Please contact me using online consult option with photos for detailed prescription.
1 person found this helpful

I have a skin problem like ringworm and I use daily terbinaforce but my skin not recover my skin.

BAMS
Ayurveda, Bangalore
Hi, Take tab Gandhak Rasayana 1tab 3 times a day and apply Six-c ointment to the affected area 2-3 times a day. Use this continuously for 1 month.

Sir I have fungal infection near penis and back side. How to control that .i am facing same problem from year but I felling Shay to go hospital. And I am using tablet TERBINAFINE TABLET 250 MG and cream EBERNET. But now after using tab griseofulvin 250 mg 1 tab od mor tab fluconazole 150 mg 1 tab twice weekly tab levocetirizine 1 tab odhs tab doxycycline 100 mg 1 tab bd for 15 days ketoconazole cream locally mor nights take this treatment for 15 days This tablet's it is clear but now speeded to testis Near testis itching and skin removing Sir. What I should do.

BHMS
Homeopath, Sindhudurg
Sir I have fungal infection near penis and back side. How to control that .i am facing same problem from year but I f...
Ringworm of groin is also known as tinea cruris or jock itch . It causes raised red sores with marked edges. This type of ringworm can spread to the buttocks, Inner thigh and external genitilia. Fungal infections of skin are the most common of all and are effectively treated with homoeopathy. This disease is more common in hot and moist weather and is more frequently seen in people who keep their feet enclosed in shoes or socks most of the time, (Athlete?s foot). It is also encouraged by the sharing of wash places and swimming pools. In frequent washing of socks and use of occlusive foot wear encourages relapses. It has been a widely acknowledged fact that homoeopathy can treat this condition effectively and without any side effects. you can Consult me for homoepathic treatment without side effects
1 person found this helpful

Popular Health Tips

Fungal Infection on Scalp: How to Treat It?

IAT, BHMS
Trichologist, Mumbai
Fungal Infection on Scalp: How to Treat It?

Ringworm of the scalp usually affects children. This is a common type of a fungal infection of the scalp and has nothing to do with the worms as the name suggests. This is treated with antifungal medications and though the antifungal shampo-is not to-effective, it might be advised along with medication.

Causes of scalp ringworm:

  • Most of the times a ringworm infection is transfered from person to person through sharing towels and touching. The fungi and its spores can remain alive on brushes, combs, sheets, furniture and unwashed towels for long. Some people are only carriers of fungi, meaning that they carry the fungi and its spores in their hair and skin but do not have any infection and symptoms. But they might pass the fungi to others who may develop the symptoms.
  • It spreads from pets like cats and dogs who are very prone to fungal infection of the skin. They easily pass their infection to children and other family members. Farm animals are also a source of fungal infection and if the farm gate is touched from where the infected cattle passes, it is enough to cause infection.
  • Also at times there is no reason and fungi infection can just happen out of the blue. Like for example, the fungi spores can get transmitted through air, they might get into the air by an infected person and land on someone else's head. This can develop into fungi and can cause infection.

Symptoms of scalp ringworm:

  1. The infection looks more like dandruff, a severe form of dandruff in different parts of the scalp. This is often mistaken to be psoriasis.
  2. In some infection there is loss of hair leading to bald patches. These patches become scaly and inflamed. The patches might have broken off small hair.
  3. Several painful pustules and boils occur on the scalp
  4. In severe infection there is boggy swelling on some part of the scalp, which is known as kerion. This might be tender and oozing and if not treated can lead to hair loss and permanent scarring.
  5. In severe infections like with pustules and kerion, one might develop high fever and the glands of the neck might swell. 

Treatment of scalp ringworm:
The treatment of the fungal infection of the scalp involves the following:

  1. Antifungal Medicines: These are usually taken in the form of tablets and following are advised:
  2. Griseofulvin: This is often the first choice and a course of 8-12 weeks is required. The tablet can be crushed and taken with water.
  3. Terbinafine: The course for this is four weeks and is important to complete the course in order to get rid of the infection.
3645 people found this helpful