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Gentamicin

Prescription vs.OTC: Prescription by Doctor required

Gentamicin helps in the treatment of a range of bacterial infections. It belongs to a group of drugs called the aminoglycoside antibiotics. The drug stops bacterial growth thus preventing or treating the infection.

The drug is mostly administered via an injection as per the doctor’s guidance. An injection may be administered after a span of 8 hours, depending on the health of the patient, age, weight, extensity of the infection and the body’s reaction to the medication. Generally certain laboratory tests, for instance a kidney function test may be done before administering the drug so as to determine the dosage that can be given. Such tests are regularly done once Gentamicin is started to check the progress of the drug and its effect on the body.

Certain common side effects of the drug include vomiting, feeling nauseous, appetite loss and stomach upset. Redness or itching at the site of the injection is very rare, if this does occur or any of the side effects worsen contact your doctor and seek relevant medical advice.

Patients should provide doctors their detailed medical history, including information about any allergies or existing health condition they suffer from before taking the injection. Especially if you suffer from medical problems like cystic fibrosis, kidney issues, Parkinson’s, or deafness inform your doctor and discuss the various possibilities of the drug use. Expecting women are also not encouraged to take this drug as it may harm the fetus. The drug is known to pass into the breast milk, but most doctors consider it safe for breast feeding mothers.

Gentamicin should be kept away from the reach of children as well as pets. In case of a missed dose, get in touch with your doctor for a new schedule. A double dosage can result in severe complications/

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Internal Medicine Specialist before using this medicine.

Bacteremia
Gentamicin is used in the treatment of bacteremia which is an infection of the blood caused by Staphylococci and Streptococcus pyogenes.
Intraabdominal Infection
Gentamicin is used in the treatment of intra-abdominal infections caused by Helicobacter pylori, Staphylococci and Streptococci.
Bacterial Meningitis
Gentamicin is used in the treatment of meningitis, which is an inflammation of the protective membranes that surround the brain and spinal cord, caused by Streptococcus pneumoniae and Neisseria meningitidis.
Gentamicin is used in the treatment of bone and joint infections like Osteomyelitis caused by Staphylococci and Streptococci species.
Skin and Soft tissue infections
Gentamicin is used to treat skin and soft tissue infections caused by Staphylococcus aureus and Streptococcus pyogenes.
Pyelonephriits
Gentamicin is used in the treatment of Pyelonephritis which is a type of kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.
Avoid if you have a known allergy to Gentamicin or any other aminoglycosides.
In addition to its intended effect, Gentamicin may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Abdominal pain Major Rare
Agitation Major Rare
Blurred vision Major Rare
Changes in urine frequency Major Rare
Hearing loss Major Rare
Dizziness when getting up suddenly from a sitting position Major Rare
Dry mouth Major Rare
Fast heartbeat Major Rare
Itching or rash Major Rare
Increased salivation Minor Rare
Depression Minor Rare
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 6 to 8 hours.
What is the onset of action?
The peak effect of this medicine can be observed in 30 to 90 minutes for an intramuscular injection and 30 minutes after an intravenous injection.
Are there any pregnancy warnings?
This medicine is not recommended for pregnant women.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
Small amounts of this medicine is excreted in the human breast milk. Discuss with the doctor about benefits and risks. Monitoring of undesired effects like diarrhea, candidiasis is necessary.
Missed Dose instructions
The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of an overdose.
India
United States
Japan
Below is the list of medicines, which contains Gentamicin as ingredient
Sigmund Promedica
Lincoln Pharmaceuticals Ltd
Merck Ltd
Karlin Pharmaceuticals & Exports Pvt Ltd
Zydus Cadila
Maneesh Pharmaceuticals Ltd
Parker Robinson Pvt. Ltd
Lesanto Laboratories
Cadila Pharmaceuticals Ltd
Nem Laboratories
Calibar Pharmaceuticals
Sigmund Promedica
Blue Cross Laboratories Ltd
Fulford India Ltd
Micro Labs Ltd
Merck Ltd
Palson Drug
Biochem Pharmaceutical Industries
Cipla Ltd
Gentamicin belongs to the class aminoglycosides. It works by binding to the 30S subunit of the bacterial ribosomes thus inhibits the protein synthesis in the bacteria and stops the growth of the bacteria.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Disease
Dehydration Major
Consume an adequate amount of water to prevent kidney injury and hearing problem. Fluid status should be monitored closely in the patients with severe diarrhea and vomiting. Frequent monitoring of kidney function tests is necessary. Dose adjustments are to be made based on the clinical condition.
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Furosemide Major
Gentamicin is not recommended with loop diuretics due to the increase in the risk of kidney injury and hearing problem. Inform the doctor if you are receiving these medicines and any symptoms of hearing loss, dizziness, numbness should be reported immediately. Frequent monitoring of kidney function tests is necessary. An alternate medicine should be considered based on the clinical condition.
Nonsteroidal anti-inflammatory drugs Moderate
Use of Gentamicin with nonsteroidal anti-inflammatory drugs like diclofenac, aspirin may increase the risk of kidney injury. Any symptoms of swelling, weight gain, increased thirst, changes in the frequency of urination should be reported to the doctor. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.
Cephalosporins Moderate
Use of Gentamicin with cephalosporins like ceftriaxone, cefotaxime may increase the risk of kidney injury. Any symptoms of swelling, weight gain, increased thirst, changes in the frequency of urination should be reported to the doctor. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.
What are you using Gentamicin for?
Skin and Soft tissue infections
Other
Bacteremia
Bacterial Meningitis
Intraabdominal Infection
Pyelonephriits
Osteomyelitis
How much was the improvement?
Excellent
Poor
Average
How long did it take before seeing improvement?
Within 2 hours
More than 2 days
How frequently did you take this medicine?
Once a day
How did you take this medicine?
With Food
What were the side effects of this medicine?
Changes in urine frequency
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Sir my mouth is acne and pimple and I use a cream gentamicin clob g So sir tell me what I do for pimple and acne which is on my mouth.

MD - Alternative Medicine
Alternative Medicine Specialist, Mumbai
Sir my mouth is acne and pimple and I use a cream gentamicin clob g So sir tell me what I do for pimple and acne whic...
Acne / Pimples Most common skin disease due to wrong feeding habit such as Irregular hours of eating, improper food, excess of starches sugar food n bakery products. Excess of fatty foods, chronic constipation and menstruation disorder in Female are some of common cause in this Also it’s found in cases of excessive use of tea, coffee, alcohol, tobacco and hence only depend on ointment’s / OTC Products n medicine’s does not serve your any purpose, but suppressed a symptom n same re-appear after some time with brutal symptoms particularly in skin diseases issue So find out where you have to correct? Fresh Juicy fruits, such as apple, pears, grapes, pineapple, lemon, or plan water either hot or cold should be Drink. Vitamin A, E, nutrition and zinc to be consider part of treatment. Treatment: 1.A teaspoonful of coriander juice mixed with pinch of turmeric powder is effective home remedy for Pimples / Acne. Mixture should be applied to the face at night after thoroughly wash every day. 2.If you have constipation or menstruation in case of Female, then remove a same, or go for treatment 3.Cap. Neem Guard - 1 daily in morning after breakfast 4.Cap Garlic Pearls - 1 daily after breakfast 5.Steam on face buy using Neem Patti / leaves thrice in a week 6.Avoid cosmetic cream available at OTC and use pure chandan and other herbs made paste along with non side effect face wash 7.Stress Management 8.Steam bath twice a week Diet: 1.In morning: A glass of lukewarm water with half a freshly –squeezed lime and Honey 2.Breakfast: Any fresh fruit and fresh milk. 3.Lunch: A bowl of freshly-prepared steamed vegetable, one or two whole wheat chapattis, and glass of butter milk or curd. 4.Afternoon: A fresh fruit or juice 5.Dinner: A large bowl of raw vegetable salad, with lime juice dressing, sprouted mung beans 6.Bedtime: A glass of fresh milk or fresh fruit 7.Avoid cosmetic cream available at OTC and use pure chandan and other herbs made paste along with non side effect face wash 8.Stress Management 9.Steam bath twice a week
3 people found this helpful

How safe using Clobetasol Propionate & Gentamicin Sulphate Cream Clop-G cream for 3 months old baby boy? Is it contain steroids?

D. C. H (pediatrics), M.B.B.S
Pediatrician,
How safe using Clobetasol Propionate & Gentamicin Sulphate Cream Clop-G cream for 3 months old baby boy? Is it contai...
Clobetasol is a local steroid and gentamycin is and antibiotic. It will depend on how long you are using and the condition for which you are using this particular preparation.
1 person found this helpful

I have itching problem since three years. Having levocetirizine and various creams but it is not completely diminishing. Please give me a prescription. Applying clobetasol propionate, Gentamicin sulphate, tolnaftate, iodochlorhydroxyquinoline & ketoconazole cream.

MBBS
General Physician, Jalgaon
I have itching problem since three years. Having levocetirizine and various creams but it is not completely diminishi...
Please Avoid oily spicy and fast food, non veg food, fish, curd, rice Go for morning and evening walk daily till good sweating Use neem soap for bath Take bath Twice a day Take Tab purim by Himalaya 2 2 for 3 mths Mahamnjishtadi kadha 20 ml twice a day for 3 months Vidangarishta 20 ml twice a day for 3 months Can take Tab atarex 15 1 sos for itching when needed.
1 person found this helpful

What is the appropriate oral medication (with dose) for chronic ringworm infection after failure of complete eradication using topical creams like clotrimazole, clobetasol, terbinafine, neomycin, gentamicin etc.

MBBS, M.D., Post Graduate Program in Pediatric Nutrition (PGPN)
Pediatrician, Noida
Itaconazole 100 mg twice a day for 21 days as well candid lotion on clean affected area followed by itaconazole powder twice a day.

I am 49 yrs old male, married, at the time of intercourse with my wife feel inflammation at the foreskin of my penis for last 2 months. I use the ointment of Gentamicin and Miconazole but find no remedy. After intercourse I find cut mark at the top of my foreskin. I am a diabetic patient. Now my PP is 180. How it can be healed?

MBBS (Gold Medalist, Hons), MS (Obst and Gynae- Gold Medalist), DNB (Obst and Gynae), Fellow- Reproductive Endocrinology and Infertility (ACOG, USA), FIAOG, MRCOG (London, UK)
Gynaecologist, Kolkata
I am 49 yrs old male, married, at the time of intercourse with my wife feel inflammation at the foreskin of my penis ...
Control sugar tightly. It may be a case of phimosis. Don't ignore it. Get it checked by doctor and get the cure.

Popular Health Tips

Meniere's Disease - What Is The Right Way To Manage It?

MBBS, MS - ENT
ENT Specialist, Ghaziabad
Meniere's Disease - What Is The Right Way To Manage It?

Meniere’s disease is a condition of the middle ear, the exact cause of which is not known. If often affects one ear and affects adults who are aged over 40. It is diagnosed by few characteristic symptoms:

There could be periods of dizziness, where the patient falls, known as “drop attacks.” These attacks are followed by long periods with no symptoms whatsoever. It is unpredictable and so a patient can never really be prepared for an attack. While it is not easy to diagnose the condition, doctors do a detailed history to confirm the diagnosis. Hearing test, CT scan, and MRI may be used to confirm the diagnosis.

Management: There is no definitive treatment for this condition. However, various options have been proposed, and many people have found them to be helpful. Some commonly used measures including diet and cognitive therapy are listed below:

  • Medications: There is no medication to attack the root cause. Medicines are used often to control dizziness, which is the most irritating symptom of this condition. Meclizine and diazepam are often used. In some people, gentamicin or corticosteroid injections are used. However, long-term use of gentamicin can cause hearing loss.
  • Salt restriction: Reducing salt intake indirectly reduces the fluid retention in the body, which helps manage the blood pressure and vertigo
  • Dietary changes: When a detailed history is taken, there are patterns which indicate that increased caffeine, chocolate, or alcohol worsen the symptoms. These are reduced with an intent to reduce the symptoms
  • Pulse treatment: A pulse of air is pushed through to the inner ear, which helps in symptom relief. This device fits into the outer ear, and when the pulse of air is pushed through, it improves fluid circulation within the middle ear, which is believed to be a cause for the condition.
  • Surgery: As a last resort, some surgical options are used:
    • A shunt is placed in the middle ear to drain out the excess fluid and maintain balance.
    • Labyrinthectomy may also be done to reduce symptoms, which may also involve removal of the eighth cranial nerve, which is believed to be the cause.
    • Hearing aids can be used if the hearing loss is severe.
    • Alternative medicines including acupressure and acupuncture are proven to reduce symptoms in some people.
    • Herbs like gingko biloba and ginger root have also been used, not with proven effect though.
  • Prevention: When possible, avoid
    • Driving
    • Operating heavy machinery
    • Swimming
    • Use of ladders
    • Being on terraces without somebody supervising

In case you have a concern or query you can always consult an expert & get answers to your questions!

3306 people found this helpful

Dizziness: Check Your Symptoms and Signs!

MD - Physician, Diploma in Otorhinolaryngology (DLO), Fellow of Academy of General Education (FAGE)
ENT Specialist, Chennai
Dizziness: Check Your Symptoms and Signs!

Are you feeling lightheaded, unbalanced or woozy lately? Are you having strange sensations in the ears and eyes? These indicate that you are suffering from dizziness, a condition affecting the body’s sensory organs. It can cause fainting at times as well. It is not a disease, but a symptom of several disorders. Dizziness is caused by inner ear disturbances, effects of medication, motion sickness and underlying health conditions, such as poor blood circulation, infections or injuries.

Test and diagnosis

If you feel dizzy for a prolonged period of time or if the dizziness occurs and reoccurs, a special treatment is required. This is because dizziness may make you prone to several risks in everyday life. Several tests are carried out to find out the cause of the dizziness. If a stroke is suspected, an MRI scan or CT scan is carried out. A physical examination is undertaken in which the way you walk and balance are observed and the nerves of the central nervous system are checked. Hearing and balance tests may also be required, which are as follows:

  • Eye movement testing in which the path of the eyes is observed while tracking an object in motion. An eye motion test may be given where cold and warm water is placed in the ear canal.
  • Head movement tests are carried out when benign paroxysmal positional vertigo is suspected.

Treatment

Treatment of dizziness includes medicines, therapies and balance exercises.

Medicines

  • Various types of medicines are used initially to control the acute phase of imbalance. Drugs are even continued for some patients for a bit longer duration depending on clinical findings..

Therapy

  • Head position maneuvers: A technique known as canalith repositioning helps in resolving dizziness quickly. It can be performed by a doctor, therapist or audiologist. The position of the head is maneuvered in the process.
  • Balance therapy: Several exercises help in making the body’s balance system lesser sensitive to motion. This technique, known as vestibular rehabilitation, is used for people suffering from dizziness due to inner ear conditions.
  • PsychotherapyThis therapy may be used for patients who experience dizziness because of anxiety disorders.
  • Use of antibiotics: An antibiotic by the name of gentamicin may be injected in the inner ear for disabling the balance function. The unaffected ear performs that function.
  • Other procedures: A procedure known as labyrinthectomy may be used for disabling the vestibular labyrinth in the affected ear.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2667 people found this helpful

Gonorrhea - How It Is Affecting Your Sexual Life?

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Sexologist, Pune
Gonorrhea - How It Is Affecting Your Sexual Life?

Gonorrhoea is transmitted infection caused when people come in a physically intimate contact. It can affect both male and female. The most vulnerable organs that are susceptible to gonorrhoea infection include rectum, urethra, and throat. In females, gonorrhoea might affect the cervix as well. Since the infection spreads from having sex, there are wide chances that the baby gets affected too. Although there could be no visible symptoms of gonorrhoea, early detection and treatment increase the chances of a permanent cure.

How does gonorrhoea affect the sexual life?
Once a person gets affected, gonorrhoea may wreak havoc on the sex life of both a male and female. In males, there could be swelling and pain in one testicle leading to difficulty in having sex. Additionally, urination after sex becomes painful. There could be a pus-like discharge from the penis thereby completely obstructing the chances of sex.

In females, there could be abdominal pain during the intercourse. Intercourse itself could be extremely painful. Apart from this, the urination after sex could be very painful. Additionally, there are chances of vaginal discharge after sex. There are high chances of vaginal bleeding after sex followed by itching of the anus. If the bacteria are very active, lymph nodes of the throat getting swollen after oral sex.

The treatment plan for gonorrhoea in adults

  1. Adults infected with the gonorrhoea bacteria are treated with antibiotics. Since gonorrhoea bacteria are increasingly becoming drug-resistant, doctors treat the patient with an antibiotic known as Ceftriaxone in the form of injection.
  2. In addition to this, two antibiotics that are prescribed to be taken in the oral form include Doxycycline and Azithromycin. There are some studies which revealed that injectable Gentamicin along with oral Azithromycin is a successful combination that can treat gonorrhoea. Furthermore, this combination proves to be highly successful in treating patients who are allergic to cephalosporin-based antibiotics.
  3. In addition to the treatment of the infected patient, the partner should also be thoroughly checked for symptoms of gonorrhoea treatment even if there exist no symptoms of the disease as such. There is a high likelihood of one partner getting infected in case the other one is infected.
  4. If a baby gets infected with gonorrhoea in the womb, he/she should get immediate eye medication to ensure that there no loss of vision when he/she is born. Babies should also get a dosage of antibiotics.
  5. Some basic hygiene such as not having sex during the course of the treatment, use of protection during sex, avoiding oral sex, avoiding sex with multiple partners etc. should be followed.

In case you have a concern or query you can always consult an expert & get answers to your questions!

3285 people found this helpful

Dizziness - Can it be a Sign of Ear Disturbance?

MBBS, MS - ENT, DNB (ENT)
ENT Specialist, Delhi
Dizziness - Can it be a Sign of Ear Disturbance?

Are you feeling lightheaded, unbalanced or woozy lately? Are you having strange sensations in the ears and eyes? These indicate that you are suffering from dizziness, a condition affecting the body’s sensory organs. It can cause fainting at times as well. It is not a disease, but a symptom of several disorders. Dizziness is caused by inner ear disturbances, effects of medication, motion sickness and underlying health conditions, such as poor blood circulation, infections or injuries.

Test and diagnosis
If you feel dizzy for a prolonged period of time or if the dizziness occurs and reoccurs, a special treatment is required. This is because dizziness may make you prone to several risks in everyday life. Several tests are carried out to find out the cause of the dizziness. If a stroke is suspected, an MRI scan or CT scan is carried out. A physical examination is undertaken in which the way you walk and balance are observed and the nerves of the central nervous system are checked. Hearing and balance tests may also be required, which are as follows:

  • Eye movement testing in which the path of the eyes is observed while tracking an object in motion. An eye motion test may be given where cold and warm water is placed in the ear canal.
  • Head movement tests are carried out when benign paroxysmal positional vertigo is suspected.

Treatment

Treatment of dizziness includes medicines, therapies and balance exercises.

Medicines

  • Water pills are prescribed when a patient has Meniere’s disease, which helps in reducing dizziness.
  • Antihistamines provide temporary relief from dizziness.

Therapy

  • Head position maneuvers: A technique known as canalith repositioning helps in resolving dizziness quickly. It can be performed by a doctor, therapist or audiologist. The position of the head is maneuvered in the process.
  • Balance therapy: Several exercises help in making the body’s balance system lesser sensitive to motion. This technique, known as vestibular rehabilitation, is used for people suffering from dizziness due to inner ear conditions.
  • PsychotherapyThis therapy may be used for patients who experience dizziness because of anxiety disorders.
  • Use of antibiotics: An antibiotic by the name of gentamicin may be injected in the inner ear for disabling the balance function. The unaffected ear performs that function.
  • Other procedures: A procedure known as labyrinthectomy may be used for disabling the vestibular labyrinth in the affected ear.

If you experience dizziness continuously, it is important for you to visit an ENT specialist. An ENT specialist deals with problems related to the ear, nose and throat and will be able to provide you with the best diagnosis and treatment for dizziness.

2512 people found this helpful

Dizziness - Is It A Symptom Of Ear Disturbance?

MS- Otorhinolaryngology, DNB- Otorhinolaryngology, MBBS, USMLF
ENT Specialist, Delhi
Dizziness - Is It A Symptom Of Ear Disturbance?

Are you feeling lightheaded, unbalanced or woozy lately? Are you having strange sensations in the ears and eyes? These indicate that you are suffering from dizziness, a condition affecting the body’s sensory organs. It can cause fainting at times as well. It is not a disease, but a symptom of several disorders. Dizziness is caused by inner ear disturbances, effects of medication, motion sickness and underlying health conditions, such as poor blood circulation, infections or injuries.

Test and diagnosis
If you feel dizzy for a prolonged period of time or if the dizziness occurs and reoccurs, a special treatment is required. This is because dizziness may make you prone to several risks in everyday life. Several tests are carried out to find out the cause of the dizziness. If a stroke is suspected, an MRI scan or CT scan is carried out. A physical examination is undertaken in which the way you walk and balance are observed and the nerves of the central nervous system are checked. Hearingand balance tests may also be required, which are as follows:

  • Eye movement testing in which the path of the eyes is observed while tracking an object in motion. An eye motion test may be given where cold and warm water is placed in the ear canal.
  • Head movement tests are carried out when benign paroxysmal positional vertigo is suspected.

Treatment

Treatment of dizziness includes medicines, therapies and balance exercises.

 

Medicines

  • Water pills are prescribed when a patient has Meniere’s disease, which helps in reducing dizziness.
  • Antihistamines provide temporary relief from dizziness.

Therapy

  • Head position maneuvers: A technique known as canalith repositioning helps in resolving dizziness quickly. It can be performed by a doctor, therapist or audiologist. The position of the head is maneuvered in the process.
  • Balance therapy: Several exercises help in making the body’s balance system lesser sensitive to motion. This technique, known as vestibular rehabilitation, is used for people suffering from dizziness due to inner ear conditions.
  • PsychotherapyThis therapy may be used for patients who experience dizziness because of anxiety disorders.
  • Use of antibiotics: An antibiotic by the name of gentamicin may be injected in the inner ear for disabling the balance function. The unaffected ear performs that function.
  • Other procedures: A procedure known as labyrinthectomy may be used for disabling the vestibular labyrinth in the affected ear.

If you experience dizziness continuously, it is important for you to visit an ENT specialist. An ENT specialist deals with problems related to the ear, nose and throat and will be able to provide you with the best diagnosis and treatment for dizziness.

Table of Content

About Gentamicin
When is Gentamicin prescribed?
What are the contraindications of Gentamicin ?
What are the side effects of Gentamicin ?
Key highlights of Gentamicin
What are the dosage instructions?
Where is the Gentamicin approved?
Medicines containing Gentamicin
How does medicine works?
What are the interactions for Gentamicin ?