Gentamicin helps in the treatment of a range of bacterial infections. It belongs to a group of drugs called aminoglycoside antibiotics. The drug stops bacterial growth thus preventing or treating the infection.
This medicine, when used topically to treat superficial infections of the skin or ophthalmic infections caused by susceptible bacteria. It also helps in preventing bacterial endocarditis prior to dental or surgical procedures.
The medicine may be administered after a span of 8 hours, depending on the health of the patient, age, weight, extensity of the infection and the body’s reaction to the medication. Expecting women are also not encouraged to take this drug as it may harm the fetus. The drug is known to pass into breast milk, but most doctors consider it safe for breastfeeding mothers.
Generally certain laboratory tests, for instance, a kidney function test may be done before administering the drug so as to determine the dosage that can be given. Such tests are regularly done once Gentamicin is started to check the progress of the drug and its effect on the body.
Gentamicin is used for the treatment of susceptible bacterial infections, normally gram-negative organisms including Pseudomonas, Proteus, Serratia, and gram-positive Staphylococcus. And also in the treatment of bone infections, respiratory tract infections, skin and soft tissue infections, as well as abdominal and urinary tract infections, endocarditis, and septicemia.
Certain common side effects of the drug include vomiting, feeling nauseous, appetite loss and stomach upset. Redness or itching at the site of the injection is very rare, if this does occur or any of the side effects worsen contact your doctor and seek relevant medical advice.
Patients should provide doctors with their detailed medical history, including information about any allergies or existing health condition they suffer from before taking the injection. Inform your doctor and discuss the various possibilities of the drug use, especially if you suffer from medical problems like -
- Cystic fibrosis
- Kidney issues
- Parkinson’s disease
Gentamicin should be kept away from the reach of children as well as pets. In case of a missed dose, get in touch with your doctor for a new schedule. A double dosage can result in severe complications.
This medicine is used to treat the following clinical conditions:
Skin And Soft Tissue Infections
How long is the duration of effect?The effect of this medicine lasts for a duration of about 6 to 8 hours.
What is the onset of action?The top effect of this medicine is observed within 30 to 90 minutes of administration.
Are there any pregnancy warnings?This medicine is not suggested for pregnant women. Consult your doctor before using it.
Is it habit forming?No habit forming tendencies are reported for Gentamicin.
Are there any breast-feeding warnings?The medicine is known to excrete through human breast milk. It is always suggested to discuss with the doctor about benefits and risks associated with Gentamicin.
Does this affect kidney function?Caution must be taken in patients with kidney disease. Adjustment of dose is required. Kindly consult your doctor before taking this medicine.
Does this affect liver function?Caution must be taken in patients with liver disease. Adjustment of dose is required. Kindly consult your doctor before taking this medicine.
Is it safe to drive while on this medicine?This medicine is expected to cause side effects like drowsiness or dizziness and may affect the consciousnesses of the patient. Thus driving must be avoided.
Are there any missed dose instructions?The missed dose can be taken as soon as possible. However, skip the missed dose if it is almost time for the next scheduled dose.
Are there any overdose instructions?Consult a doctor if symptoms of overdose are suspected.
Below is the list of medicines, which contains Gentamicin as ingredient
This medication works by works by binding to the 30S subunit of the bacterial ribosomes thus inhibits protein synthesis in bacteria and stops the growth of the bacteria.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
FurosemideGentamicin is not recommended with loop diuretics due to the increase in the risk of kidney injury and hearing problem. Inform the doctor if you are receiving these medicines and any symptoms of hearing loss, dizziness, numbness should be reported immediately. Frequent monitoring of kidney function tests is necessary. An alternate medicine should be considered based on the clinical condition.
Nonsteroidal anti-inflammatory drugsUse of Gentamicin with nonsteroidal anti-inflammatory drugs like diclofenac, aspirin may increase the risk of kidney injury. Any symptoms of swelling, weight gain, increased thirst, changes in the frequency of urination should be reported to the doctor. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.
CephalosporinsUse of Gentamicin with cephalosporins like ceftriaxone, cefotaxime may increase the risk of kidney injury. Any symptoms of swelling, weight gain, increased thirst, changes in the frequency of urination should be reported to the doctor. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.
OthersIncreased toxicity: Neuromuscular blocking agents may increase neuromuscular blockade.
Interaction with Disease
DehydrationAlways consume good amount of water to avoid any kidney injury and hearing problem caused due to dehydration.
OthersNot intended for long-term therapy due to toxic hazards associated with extended administration; pre-existing renal insufficiency, vestibular or cochlear impairment, myasthenia gravis, hypocalcemia, conditions which depress neuromuscular transmission.
Interaction with Food
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Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.