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Clobetamil G Cream

Manufacturer: Merck Ltd
Medicine composition: Clobetasol, Gentamicin
Prescription vs.OTC: Prescription by Doctor not required

Clobetamil cream is a combination of two medicines- clobetasol and germaticin. Clobetasol belongs to a class of drugs called corticosteroids; it reduces the production and effects of chemicals in the body that cause inflammation. Germaticin belongs to a class of drugs known as aminoglycoside antibiotics; it works against both Gram-positive and Gram-negative bacteria.

Clobetamil is used to treat and prevent inflammation, redness of the skin and itching due to eczema, allergy, dermatitis, rashes and psoriasis. It is also used to treat several autoimmune diseases like vitiligo, alopecia areata, lichen planus and lichen sclerosus.

It is available as a shampoo, ointment, mousse and emollient cream. Apply the cream on the affected area twice every day as per your doctor’s instructions. Apply the exact amount as directed by the doctor. Avoid contact with your face, eyes, underarms and groin. Continue applying it as long as the doctor recommends. Do not continue it post the expiration date of the medicine to avoid skin infections.

Clobetamil cream is helpful in treating the below provided problems:

Clobetamil cream causes side effects such as:

  • Application Site Reactions (Burning Sensation)

  • Dry Skin

  • Redness Of Skin

  • Itching Of Skin

  • Cough

  • Sore Throat

  • Body Pain

  • Headache

  • How long is the duration of effect?

    The duration of effect is not clinically evaluated.

  • What is the onset of action?

    The onset of action of the medicine varies with the skin condition and the extent of absorption of the medicine.

  • Are there any pregnancy warnings?

    Consult your doctor before using this cream. It may cause harmful effects on your baby’s health.

  • Is it habit forming?

    It does not have any addictive properties.

  • Are there any breast-feeding warnings?

    It is safe for women who are breastfeeding and for their babies.

  • Is It safe with alcohol?

    The interaction of Clobetamil with alcohol is unknown. Consult a doctor before proceeding.

  • Is it safe to drive while on this medicine?

    It is safe to drive while applying Clobetamil cream since it does not make you sleepy.

  • Does this affect kidney function?

    It is not harmful to the kidney.

  • Does this affect liver function?

    Clobetamil cream does not interfere with normal liver functioning.

Below is the list of medicines, which have the same composition, strength and form as Clobetamil G Cream , and hence can be used as its substitute.

  • Are there any missed dose instructions?

    Apply the missed dose as soon as it is possible. But do not apply it if its time for the next dose.

  • Are there any overdose instructions?

    If you overdose, contact your doctor immediately. You will suffer from severe skin infections and allergies.

Clobetasol belongs to corticosteroids. It works as an anti-inflammatory by inhibiting the metabolism of arachidonic acid by inhibiting phospholipase A2 thus inhibits the production of inflammatory mediators like prostaglandins and leukotrienes. On the other hand, the other constituent of the medicine, Gentamicin belongs to the class aminoglycosides. It works by binding to the 30S subunit of the bacterial ribosomes thus inhibits the protein synthesis in the bacteria and stops the growth of the bacteria.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Interaction of this medicine with alcohol is still unknown. Doctor’s consultation is advised.

  • Interaction with Medicine

    Clobetamil cream interacts severely with drugs like Tacrolimus, Bacitracin, Capreomycin and Furosemide. It moderately interacts with Aspirin, Paracetamol, Caffeine and Deferasirox. Avoid these drugs while applying this cream since they modify the effects of the cream and result in severe side-effects.

  • Interaction with Disease

    It interacts severely in patients with pre-existing liver disease, kidney disease, high blood sugar, Parkinson’s disease and Cushing’s syndrome.

  • Interaction with Food

    Clobetamil does not react with any food. No changes to the diet are required.

Ques: What is Clobetamil G Cream?

Ans: Clobetamil Cream is a medication which has Clobetasol Topical and Gentamicin Topical as active elements present in it. This medicine performs its action by activating the phospholipase A2 inhibitory proteins, binding to 30 S ribosomal subunit, providing the ability to avoid the synthesis of the proteins, constrict the growth and reproduction of bacteria. Clobetamil is used to treat conditions such as Minor bacterial skin infections, Redness, itching, dryness and swelling of skin and scalp, Inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, Folliculitis, Bacterial infections, etc.

Ques: What are the uses of Clobetamil G Cream?

Ans: Clobetamil Cream is a medication, which is used for the treatment and prevention from conditions such as Inflammation of inner layer of the heart, Psoriasis, Blood poisoning, Gynecological infections, Paronychia, Inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Apart from these, it can also be used to treat conditions like Folliculitis, Bacterial infections, Redness, itching, dryness and swelling of the scalp, Diseases from uncooked meat, Pus-filled swelling, Meninges inflammation, and Furunculosis. The patient should inform the doctor about any ongoing medications and treatment before using Clobetamil to avoid undesirable effects.

Ques: What are the Side Effects of Clobetamil G Cream?

Ans: Clobetamil is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of this Cream are as follows: Burning sensation at the application site, Dry skin, Redness of the skin, Itching of skin, Cough, Sore throat, Body pain, and Headache. It is a list of possible side-effects which may occur due to the constituting ingredients of Clobetamil.

Ques: What are the instructions for storage and disposal Clobetamil G Cream?

Ans: Clobetamil Cream should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects. It is a prescribed medication.

Ques: What are the precautions needed to be taken while using Clobetamil G?

Ans: Clobetamil is an ointment which should not be used on the face and contact with eyes should be avoided. Do not apply a bandage or dressing to the area being treated, as this will increase absorption of this medication and increase the risk of side effects. This ointment should only be used for the condition it is prescribed for. Do not use it for any other condition without consulting your doctor. Do not give it to other people even if their condition appears to be the same. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

Ques: How long do I need to use clobetamil g cream before I see improvement in my condition?

Ans: In most of the cases, the average time taken by this medication to reach its peak effect is around 1 to 3 days, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to consume this medication.

Ques: At what frequency do I need to use clobetamil g cream?

Ans: This medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

Ques: Should I use clobetamil g cream empty stomach, before food or after food?

Ans: This medication is commonly used by applying it to the affected area. As this medication is for external use, the action of salts involved in this medication does not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
General Physician
Table of Content
About Clobetamil G Cream
What are the uses of Clobetamil G Cream
What are the contraindications of Clobetamil G Cream ?
What are the side effects of Clobetamil G Cream ?
Key highlights of Clobetamil G Cream
What are the substitutes for Clobetamil G Cream ?
What are the dosage instructions?
How does this medication work?
What are the interactions of Clobetamil G Cream ?
FAQs about Clobetamil G Cream