Clobetamil cream is a combination of two medicines- clobetasol and germaticin. Clobetasol belongs to a class of drugs called corticosteroids; it reduces the production and effects of chemicals in the body that cause inflammation. Germaticin belongs to a class of drugs known as aminoglycoside antibiotics; it works against both Gram-positive and Gram-negative bacteria.
Clobetamil is used to treat and prevent inflammation, redness of the skin and itching due to eczema, allergy, dermatitis, rashes and psoriasis. It is also used to treat several autoimmune diseases like vitiligo, alopecia areata, lichen planus and lichen sclerosus.
It is available as a shampoo, ointment, mousse and emollient cream. Apply the cream on the affected area twice every day as per your doctor’s instructions. Apply the exact amount as directed by the doctor. Avoid contact with your face, eyes, underarms and groin. Continue applying it as long as the doctor recommends. Do not continue it post the expiration date of the medicine to avoid skin infections.
How long is the duration of effect?
The duration of effect is not clinically evaluated.
What is the onset of action?
The onset of action of the medicine varies with the skin condition and the extent of absorption of the medicine.
Are there any pregnancy warnings?
Consult your doctor before using this cream. It may cause harmful effects on your baby’s health.
Is it habit forming?
It does not have any addictive properties.
Are there any breast-feeding warnings?
It is safe for women who are breastfeeding and for their babies.
Is It safe with alcohol?
The interaction of Clobetamil with alcohol is unknown. Consult a doctor before proceeding.
Is it safe to drive while on this medicine?
It is safe to drive while applying Clobetamil cream since it does not make you sleepy.
Does this affect kidney function?
It is not harmful to the kidney.
Does this affect liver function?
Clobetamil cream does not interfere with normal liver functioning.
Below is the list of medicines, which have the same composition, strength and form as Clobetamil G Cream , and hence can be used as its substitute.
Are there any missed dose instructions?
Apply the missed dose as soon as it is possible. But do not apply it if its time for the next dose.
Are there any overdose instructions?
If you overdose, contact your doctor immediately. You will suffer from severe skin infections and allergies.
Clobetasol belongs to corticosteroids. It works as an anti-inflammatory by inhibiting the metabolism of arachidonic acid by inhibiting phospholipase A2 thus inhibits the production of inflammatory mediators like prostaglandins and leukotrienes. On the other hand, the other constituent of the medicine, Gentamicin belongs to the class aminoglycosides. It works by binding to the 30S subunit of the bacterial ribosomes thus inhibits the protein synthesis in the bacteria and stops the growth of the bacteria.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction of this medicine with alcohol is still unknown. Doctor’s consultation is advised.
Interaction with Medicine
Clobetamil cream interacts severely with drugs like Tacrolimus, Bacitracin, Capreomycin and Furosemide. It moderately interacts with Aspirin, Paracetamol, Caffeine and Deferasirox. Avoid these drugs while applying this cream since they modify the effects of the cream and result in severe side-effects.
Interaction with Disease
Interaction with Food
Clobetamil does not react with any food. No changes to the diet are required.
Ques: What is Clobetamil G Cream?
Ques: What are the uses of Clobetamil G Cream?
Ques: What are the Side Effects of Clobetamil G Cream?
Ques: What are the instructions for storage and disposal Clobetamil G Cream?
Ques: What are the precautions needed to be taken while using Clobetamil G?
Ques: How long do I need to use clobetamil g cream before I see improvement in my condition?
Ques: At what frequency do I need to use clobetamil g cream?
Ques: Should I use clobetamil g cream empty stomach, before food or after food?
Gentamicin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:https://druginfo.nlm.nih.gov/drugportal/rn/1403-66-3
Clobetasol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:https://druginfo.nlm.nih.gov/drugportal/name/clobetasol
Clobetasol (Clovate): Information You Need To Know- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 25 April 2019]. Available from:https://www.drugsbanks.com/clovate/
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