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Clobetamil G Cream

Manufacturer :  Merck Ltd
Medicine Composition :  Clobetasol, Gentamicin
Prescription vs OTC : Prescription by Doctor not required

About Clobetamil G Cream

Clobetamil G Cream is a well-known prescription extensively used by major dermatologists to cure bacterial skin cultures, inflammations, redness, itching, eczema, psoriasis, allergy rash and multiple skin infections.

It is also used for the short-term relief of inflammation of moderate to severe corticosteroid-responsive dermatosis (very high potency topical corticosteroid).

Clobetamil G Cream is enriched with Clobetasol and Gentamicin. Topical base compounds which help in the growth and reproduction of bacteria cultures on the applied area. This cream also acts as a strong Corticosteroid by treating the inflammation sensations and swelling sustained with Clobetasol interactions.

The clobetasol and gentamicin compositions in the Clobetamil G Cream base helps in activating the inhibitory epidermal proteins which results in reduction of bacterial growth preventing the synthesis of the skin friendly proteins.

This cream is widely prescribed for dermatitis and skin related infections. It is only suggested for external use and it should not be applied without consulting your personal physician.

A thin film of cream or ointment is effective; do not overuse. Do not use tight-fitting diapers or plastic pants on children being treated in the diaper area. Use only as prescribed and for no longer than the period prescribed.

Apply sparingly in light film, rub in lightly. Avoid contact with eyes. Notify physician if condition being treated persists or worsens, you can gently massage cream into affected area until foam disappears.

    What are the uses of Clobetamil G Cream

    What are the contraindications of Clobetamil G Cream ?

    What are the side effects of Clobetamil G Cream ?

    • Application Site Reactions (Burning Sensation)

    • Dry Skin

    • Redness Of Skin

    • Itching Of Skin

    • Increased Hair Growth

    • Easy Bruising And Bleeding

    Key highlights of Clobetamil G Cream

    • How long is the duration of effect?

      No specific data is available to be able to define the duration for the effect of this medicine. The duration of the effect varies on the prescription quantity, which differs for every symptom respectively.

    • What is the onset of action?

      The onset of action of the medicine varies with the skin condition and the extent of absorption of the medicine.

    • Are there any pregnancy warnings?

      Pregnant women should consult a doctor before being prescribed for this drug. The doctor needs to be well informed regarding any previous clobetasol related allergies as usage without diagnosis can cause further allergic reactions.

    • Is it habit forming?

      This medicament has not been found to be habit forming or addictive in any way for the patients. However, continuous application to the impacted area should not be more than 50 grams per week or longer than 2 weeks.

    • Are there any breast-feeding warnings?

      It is safe for women who are breastfeeding and for their babies.

    • Is It safe with alcohol?

      This medicament comes in compound application bases to used externally over the skin. There are no lab records suggesting a prohibition of the course of this medicine with alcohol.

    • Is it safe to drive while on this medicine?

      This medicament doesn’t impact decision making mental metabolism or balance impeding impulses. Since it is applied externally, one can easily drive after applying this cream.

    • Does this affect kidney function?

      It is not harmful to the kidney.

    • Does this affect liver function?

      Clobetamil cream does not interfere with normal liver functioning.

    What are the substitutes for Clobetamil G Cream ?

    Below is the list of medicines, which have the same composition, strength and form as Clobetamil G Cream , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Apply the missed dose as soon as it is possible. But do not apply it if its time for the next dose.

    • Are there any overdose instructions?

      If you overdose, contact your doctor immediately. You will suffer from severe skin infections and allergies.

    How does this medication work?

    Clobetasol belongs to corticosteroids. It works as an anti-inflammatory by inhibiting the metabolism of arachidonic acid by inhibiting phospholipase A2 thus inhibits the production of inflammatory mediators like prostaglandins and leukotrienes. On the other hand, the other constituent of the medicine, Gentamicin belongs to the class aminoglycosides. It works by binding to the 30S subunit of the bacterial ribosomes thus inhibits the protein synthesis in the bacteria and stops the growth of the bacteria.

      What are the interactions of Clobetamil G Cream ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

      • Interaction with Alcohol

        Interaction of this medicine with alcohol is still unknown. Doctor’s consultation is advised.

      • Interaction with Medicine

        Clobetamil cream interacts severely with drugs like Tacrolimus, Bacitracin, Capreomycin and Furosemide. It moderately interacts with Aspirin, Paracetamol, Caffeine and Deferasirox. Avoid these drugs while applying this cream since they modify the effects of the cream and result in severe side-effects.

      • Interaction with Disease

        Since this cream is not subjected to ingestion, it has no lab results concluding the study of mixed interactions with other prescribed medicines. If you are already using regular skin ointments - cosmetic or medical, please don’t forget to consult with your nearest doctor immediately for dosage recommendations.
      • Interaction with Food

        Clobetamil does not react with any food. No changes to the diet are required.

      FAQs about Clobetamil G Cream

      • Ques : What is Clobetamil G Cream?

        Ans : Clobetamil Cream is a medication which has Clobetasol Topical and Gentamicin Topical as active elements present in it. This medicine performs its action by activating the phospholipase A2 inhibitory proteins, binding to 30 S ribosomal subunit, providing the ability to avoid the synthesis of the proteins, constrict the growth and reproduction of bacteria. Clobetamil is used to treat conditions such as Minor bacterial skin infections, Redness, itching, dryness and swelling of skin and scalp, Inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, Folliculitis, Bacterial infections, etc.

      • Ques : What are the uses of Clobetamil G Cream?

        Ans : Clobetamil Cream is a medication, which is used for the treatment and prevention from conditions such as Inflammation of inner layer of the heart, Psoriasis, Blood poisoning, Gynecological infections, Paronychia, Inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Apart from these, it can also be used to treat conditions like Folliculitis, Bacterial infections, Redness, itching, dryness and swelling of the scalp, Diseases from uncooked meat, Pus-filled swelling, Meninges inflammation, and Furunculosis. The patient should inform the doctor about any ongoing medications and treatment before using Clobetamil to avoid undesirable effects.

      • Ques : What are the Side Effects of Clobetamil G Cream?

        Ans : Clobetamil is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of this Cream are as follows: Burning sensation at the application site, Dry skin, Redness of the skin, Itching of skin, Cough, Sore throat, Body pain, and Headache. It is a list of possible side-effects which may occur due to the constituting ingredients of Clobetamil.

      • Ques : What are the instructions for storage and disposal Clobetamil G Cream?

        Ans : Clobetamil Cream should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects. It is a prescribed medication.

      • Ques : What are the precautions needed to be taken while using Clobetamil G?

        Ans : Clobetamil is an ointment which should not be used on the face and contact with eyes should be avoided. Do not apply a bandage or dressing to the area being treated, as this will increase absorption of this medication and increase the risk of side effects. This ointment should only be used for the condition it is prescribed for. Do not use it for any other condition without consulting your doctor. Do not give it to other people even if their condition appears to be the same. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

      • Ques : How long do I need to use clobetamil g cream before I see improvement in my condition?

        Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 to 3 days, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to consume this medication.

      • Ques : At what frequency do I need to use clobetamil g cream?

        Ans : This medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

      • Ques : Should I use clobetamil g cream empty stomach, before food or after food?

        Ans : This medication is commonly used by applying it to the affected area. As this medication is for external use, the action of salts involved in this medication does not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use.


      • Gentamicin- Drug Information Portal [Internet]. 2019 [Cited 24 April 2019]. Available from:

      • Clobetasol- Drug Information Portal [Internet]. 2019 [Cited 25 April 2019]. Available from:

      • Clobetasol (Clovate): Information You Need To Know- Drugs Bank [Internet]. 2018 [Cited 25 April 2019]. Available from:

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Rohini DhillonMBA( CHA), MBBS, PGDMCHGeneral Physician

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