Common Specialities
{{speciality.keyWord}}
Common Issues
{{issue.keyWord}}
Common Treatments
{{treatment.keyWord}}

Overview

Cystic Fibrosis - Symptom, Treatment And Causes

What is Cystic fibrosis?

Cystic fibrosis is a disorder which can cause chronic damage to the digestive system, lungs and other organs of the body. Cystic fibrosis affects the cells which produce digestive juices, sweat and mucus. These fluids are slippery and thin. People who have Cystic fibrosis usually have thick and sticky secretions. This is caused by a defective gene. Instead of becoming a lubricant, the secretions plug up the passageways, ducts and tubes in the pancreas and lungs.

What causes cystic fibrosis?

During Cystic fibrosis a mutation in the gene transform a protein which regulates movement in and out of these cells. This results in sticky and thick mucus in the reproductive, digestive and respiratory system. A lot of defects can occur which usually depends on the severity of this disorder. Children can develop Cystic fibrosis if one or both the parent had this disease.

Risk factors of Cystic fibrosis:

  • Family history- Since Cystic fibrosis is a hereditary disease, it tends to run in the family.
  • Race- Though Cystic fibrosis can affect people of all races, it is more common in people belonging to the Northern European ancestry.

Complications of Cystic fibrosis:

  • Bronchiectasis (Damaged airways)- Cystic fibrosis can cause bronchiectasis. This condtion damages the airways and makes it difficult to clear the mucus form the bronchial tubes and move air out of the lungs.
  • Chronic infections- Mucus n the sinuses and lungs are an ideal breeding spot for fungi and bacteria. People who have Cystic fibrosis are more prone in developing pneumonia, bronchitis and sinus infections.
  • Nasal polyps (growths inside the nose)- Since the lining of the nose tends to be swollen and inflamed, it can develop fleshy and soft growth (polyps).
  • Hemoptysis (coughing blood)- Cystic fibrosis can sometimes cause thinning in the airway walls. Teenagers and adults who have Cystic fibrosis can also cough up blood in severe cases.
  • Pneumothorax- In this condition the air starts to collect in the empty space which separates the chest walls from the lungs. Pneumothorax can also cause breathlessness and chest pain.
  • Nutritional deficiencies- Many times, thick mucus can create obstruction the tubes which carry enzymes aiding in digestion from the pancreas to the intestines. In such cases, the body fails to absorb fat-soluble vitamins, fats and proteins.
  • Distal intestinal obstruction syndrome (DIOS)- This condition is characterized by the complete or partial blockage where the large intestine meets the small intestine.
Can't be cured, but treatment helps Require medical diagnosis Lab test always required Chronic: can last for years or be lifelong Non communicable
Symptoms
Repeated lung infections. Inability to gain weight. Fatty stools.

Popular Health Tips

Cystic Fibrosis - 5 Strange Signs You Must Know About!

MBBS, MD - TB & Chest, Fellowship Training Intensive Care, Fellow College of Chest physicians, European Diploma in Respiratory Medicine, Interventional Pulmonology , Greece, European Diploma in Intensive Care Medicine, Fellow Indian college of critical care
Pulmonologist, Gurgaon
Cystic Fibrosis - 5 Strange Signs You Must Know About!

Do you know about a condition called cystic fibrosis that makes your baby’s skin taste very salty after birth? The condition changes over time, in which the body makes sweat and mucus, and also affects the digestive system and lung functioning. The condition generally occurs because of a flawed gene. This is a severe and life-threatening disease that affects different people in different ways.

Causes
The gene, called CTFR is present in all humans. It makes a protein that controls the amount of water and salt, which get moved in and out of your cells. In the case of cystic fibroids, the CTFR gene is broken. This happens when a person inherits two bad copies of this specific gene. One bad CFTR gene may cause your cells to make the wrong or imbalanced amount of water and salt. Because of this, your body becomes unable to get the supply of sufficient nutrients and oxygen that are lost through sweating.

Symptoms
There are several symptoms associated with cystic fibroids that include the following:

  1. It is likely for you to cough up thin mucus, along with shortness of breath, and wheezing.
  2. The development of polyps in your nose is indicated.
  3. Sinus infections, pneumonia, or bronchitis may occur.
  4. Your stool may be oily, bulky, and with a foul odor.
  5. Liver diseases and gallstones may develop later in life because of cystic fibroids.

Treatment
There is no certain treatment for cystic fibroids. However, there are various treatment procedures that are used for providing relief to the symptoms of the condition. This allows an affected patient to breathe easily, feel better, and experience lesser stomach infections. You can opt for airway clearance technique that helps you with your breathing. The procedure involves the clearance of mucus from your lungs. This procedure is carried out in several ways and special devices may be used during the proceedings.

  • Certain inhaled drugs like steroids, salt solutions, and antibiotics are used for thinning your mucus layers, and for clearing lung infections.
  • If your pancreas do not work properly, you may be prescribed enzyme pills for the digestion of fats and protein, and for the absorption of more nutrients from the food you consume.
  • You may also be prescribed vitamin A, D, and E supplements for getting these nutrients, which are not being absorbed by your intestine.
  • You must consult a doctor on experiencing any symptom of cystic fibrosis in your baby. This will allow the condition to be diagnosed at an early stage, thereby preventing further worsening. Consult an expert & get answers to your questions!
3135 people found this helpful

Influenza Vaccine - Why is it Important for Kids?

Senior Residency, MD - Paediatrics, MBBS
Pediatrician, Gurgaon
Influenza Vaccine - Why is it Important for Kids?

Influenza is more commonly known as the flu. It is an infection that affects the respiratory system and is caused by the influenza virus. This injection is recommended for kids who are under the age of 6 months. It ensures that the baby is safeguarded from the virus during an influenza outbreak. Since the nature of virus changes year on year, the immunity doesn’t last for more than 1 year. This vaccination is ideally taken during the month of October and November. The effect of the vaccination typically lasts for 6-8 months.

Ideally, kids who have never had a flu vaccination should take 2 vaccinations within 4 weeks. Kids who have received a shot of flu should undertake this vaccination once in a year. This arrangement is ideal up to 9 years of age. Flu shot is extremely important for a kid due to the following reasons:

  • It saves a kid from chronic lung and heart disorders such as asthma and cystic fibrosis
  • Kids suffering from immune deficiency, cancer, and HIV should take this vaccination to avoid further complication of the existing disease
  • Kids suffering from diabetes, kidney diseases, and metabolic disorders should go for this vaccination without a second thought
  • Kids suffering from a neurological disorder, haemoglobin deficiency, and anaemia should take this vaccination to refrain from the risk of aggravation of the present disease
  • Pregnant women should ideally take it for the safeguarding the fetus

Flu shot should not be taken be taken if:
1. A baby is under the age of 6 months.
2. The baby has thimerosal allergy.

Is flu shot safe?
The flu shot is considered to be very safe. It does not result in flu. Few side effects include:
a. Soreness of the place where the needle is injected. This doesn’t last for more than a couple of day.
b. Body ache and mild fever for the first couple of days after the vaccination is done.
c. There is little to no pain in the place where the injection is injected by the doctor.

What is nasal flu vaccine?
This is an influenza dose that is not injected into the body, but given in the form of nasal spray. Healthy kids above the age of 2 years are fit to get this injection. For those kids who have a history of chronic illness should check with their doctor to go ahead with nasal spray. Each dose is given in each nostril. Like the influenza vaccine, nasal flu vaccine should be undertaken once for those who have already taken this dose once. Kids who have not undergone this vaccination are eligible for 2 dosages each 4 weeks apart from each other. If you wish to discuss about any specific problem, you can consult a doctor.

2545 people found this helpful

Cystic Fibrosis - Therapies That You Can Go For!

MBBS Bachelor of Medicine and Bachelor of Surgery, MD - Chest & TB
Pulmonologist, Faridabad
Cystic Fibrosis - Therapies That You Can Go For!

Cystic fibrosis is a genetic condition, which primarily affects the lungs and persistence of this condition might lead to severe breathing problems and loss of lung function. If you have inherited two copies of the defective gene from your parents, you are likely to suffer from this disease. Cystic Fibrosis causes a buildup of thick mucus in your lungs and affects other organs such as the kidneys, pancreas and the intestines in your body.

It isn't very uncommon as one out of fifty people in Asia is a carrier of this disease. The disease gets its name from the cysts formed in the pancreas of the sufferer. However, this disease can be detected by testing the quantity of salt present in your sweat. Prenatal testing for Fibrosis is another method to test if your newborn is likely to contract a lung infection.

Complications faced due to cystic fibrosis include:

  1. Serious sinus infections
  2. Serious damage in lungs due to inflammation and incessant infection
  3. Malnutrition
  4. Complication in breaking down protein
  5. Respiratory tract contamination

If you observe one or more of the following symptoms, you might be suffering from Cystic Fibrosis:

  1. Salty-tasting skin
  2. Bowel obstruction caused due to meconium ileus (obstruction of the bowels)
  3. Persistent coughing with phlegm discharge
  4. Shortness of breath while engaging in a physical task
  5. Stunted or measly growth despite healthy lifestyle habits
  6. Infertility in males

If you're suffering from cystic fibrosis, there isn't any particular treatment which is recommended due to the varying degrees of it found in people. However, consultation with a medical practitioner and an individualised treatment plan can help you minimise the risks and lead a better life.

Diagnosis:

Diagnosis of Cystic fibrosis can be made by measuring the quality of salt i.e. the amount of chloride in your sweat (sweat chloride test). Genetic testing for CFTR gene mutation detection can also be done at specialized centres. 

Some therapies you can opt for are:

  • Airway clearance: This therapy helps sift the thick layer of mucus around your organs. Some people have also chosen to use the inflatable vest which vibrates around your chest, thereby, thinning and loosening the layer of mucus.
  • Inhaled medicines: Another breakthrough in the field of respiratory medicine, this method requires the patient to sniff a liquid consisting of mist, which is inhaled with the aid of a nebuliser. This method is known to be beneficial for opening airways.
  • Pancreatic enzyme supplements: Along with multivitamins, these specially designed supplements are known to cater to your pancreas with the much-needed nutrients and they need to be consumed with every meal.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2605 people found this helpful

5 Strange Signs You Must Know About Cystic Fibrosis!

MBBS, MD - Pulmonary Medicine
Pulmonologist, Faridabad
5 Strange Signs You Must Know About Cystic Fibrosis!

Do you know about a condition called cystic fibrosis that makes your baby’s skin taste very salty after birth? The condition changes over time, in which the body makes sweat and mucus, and also affects the digestive system and lung functioning. The condition generally occurs because of a flawed gene. This is a severe and life-threatening disease that affects different people in different ways.

Causes
The gene, called CTFR is present in all humans. It makes a protein that controls the amount of water and salt, which get moved in and out of your cells. In the case of cystic fibroids, the CTFR gene is broken. This happens when a person inherits two bad copies of this specific gene. One bad CFTR gene may cause your cells to make the wrong or imbalanced amount of water and salt. Because of this, your body becomes unable to get the supply of sufficient nutrients and oxygen that are lost through sweating.

Symptoms
There are several symptoms associated with cystic fibroids that include the following:

  1. It is likely for you to cough up thin mucus, along with shortness of breath, and wheezing.
  2. The development of polyps in your nose is indicated.
  3. Sinus infections, pneumonia, or bronchitis may occur.
  4. Your stool may be oily, bulky, and with a foul odor.
  5. Liver diseases and gallstones may develop later in life because of cystic fibroids.

Treatment
There is no certain treatment for cystic fibroids. However, there are various treatment procedures that are used for providing relief to the symptoms of the condition. This allows an affected patient to breathe easily, feel better, and experience lesser stomach infections. You can opt for airway clearance technique that helps you with your breathing. The procedure involves the clearance of mucus from your lungs. This procedure is carried out in several ways and special devices may be used during the proceedings.

  • Certain inhaled drugs like steroids, salt solutions, and antibiotics are used for thinning your mucus layers, and for clearing lung infections.
  • If your pancreas do not work properly, you may be prescribed enzyme pills for the digestion of fats and protein, and for the absorption of more nutrients from the food you consume.
  • You may also be prescribed vitamin A, D, and E supplements for getting these nutrients, which are not being absorbed by your intestine.
  • You must consult a doctor on experiencing any symptom of cystic fibrosis in your baby. This will allow the condition to be diagnosed at an early stage, thereby preventing further worsening.

Nasal Polyposis In Cystic Fiborsis

MD - Bio-Chemistry, MF Homeo (London), DHMS (Diploma in Homeopathic Medicine and Surgery), BHMS
Homeopath, Kolkata
Nasal Polyposis In Cystic Fiborsis

Cystic fibrosis should be suspected in any child which fails to thrive with malabsorption or rectal prolapse; with chronic or recurrent cough with sputum; or with cirrhosis portal hypertension. Difficulties arise where there is little involvement of either the pancreas or lung or when manifestations appear in older children or even later. Evidence should be sought for pancreatic insufficiency. The high concentration of sodium in sweat parotid secretion is of major diagnostic value. The normal sweat sodium concentration rises from a mean value of 22 mmoi/i in infancy to 55 mmoi/i in adults. Values above 70 mmoi/i are diagnostic in infants, but not so in adolescents adults. In cystic fibrosis, however, the fall in sweat sodium concentration after 9a - fluorohydrocortisone is usually less than 10% whereas in normals the fall is much greater. With respiratory infection there is usually a polymorphonuclear leucocytosis. The chest radiograph may show only parallel line shadows cast by bronchial walls in the more peripheral parts of the lung. Ill - defined nodules or patchy clouding up to 10 - 20 mm in size may appear these shadows may cavitate. Ring shadows honeycombing, segmental or lobar consolidation with or without atelectasis usually under 1 - 2 years of age, enlarged hilar nodes are also seen. None of these shadows are diagnostic alone, but in the aggregate they are very characteristic.

Etiology: - chronic naso - pharyngeal allergy. Chronic bacterial viral infection. Vasomotor disturbances.

Symptoms: - *onset insidious. * nasal obstruction, uniateral or bilateral.*anosmia, *epiphora.* post nasal drip.* snoring.

Signs:- reveals ethmoidal polypi. Bilateral. Multiple  other.

Patient homeopathic treatment for symptomatic signs or other sig base medician apply.

1 person found this helpful

Popular Questions & Answers

Cect chest reveals small fibrosis lesions in both fields with subcentimeter sized lymphnoed in mediastinum, indicating sequelae of previous infective pathology.

MBBS, DM - Cardiology, md medicine
Cardiologist, Bhopal
If you are asymptomatic. No need of further evaluation. Just follow. But if you have any gastro intestinal symptoms consult gastro- enetrologist. Actually it's difficult to evaluate small size sub centermeter lymph node. Sometime they having no significant. So need to clinicaly correlation.
1 person found this helpful

I am 28 years male. My Fibro scan results are as follows: CAP (dB/m)-median 381 E (kPa)-Median 5 IQR .5 IQR/med 10% what do these result indicate?

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
FibroScan results range from 2.5 kPa to 75 kPa. Between 90–95% of healthy people without liver disease will have a liver scarring measurement <7.0 kPa (median is 5.3 kPa. YOur result is high and need to Assessed with general check up.

What is fibrosis apities both side and what is its treatment. Please give brief answer for the treatment.

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
Appetite stimulants, although efficacious in treating malnutrition in CF, should only be prescribed if decreased food intake secondary to inadequate appetite is the principal cause of the malnutrition and all other contributing factors have been assessed, ruled-out or treated. the use of several appetite stimulants used in CF and other diseases to improve appetite and maximize caloric intake