Common Specialities
{{speciality.keyWord}}
Common Issues
{{issue.keyWord}}
Common Treatments
{{treatment.keyWord}}

Overview

Cystic Fibrosis - Symptom, Treatment And Causes

What is Cystic fibrosis?

Cystic fibrosis is a disorder which can cause chronic damage to the digestive system, lungs and other organs of the body. Cystic fibrosis affects the cells which produce digestive juices, sweat and mucus. These fluids are slippery and thin. People who have Cystic fibrosis usually have thick and sticky secretions. This is caused by a defective gene. Instead of becoming a lubricant, the secretions plug up the passageways, ducts and tubes in the pancreas and lungs.

What causes cystic fibrosis?

During Cystic fibrosis a mutation in the gene transform a protein which regulates movement in and out of these cells. This results in sticky and thick mucus in the reproductive, digestive and respiratory system. A lot of defects can occur which usually depends on the severity of this disorder. Children can develop Cystic fibrosis if one or both the parent had this disease.

Risk factors of Cystic fibrosis:

  • Family history- Since Cystic fibrosis is a hereditary disease, it tends to run in the family.
  • Race- Though Cystic fibrosis can affect people of all races, it is more common in people belonging to the Northern European ancestry.

Complications of Cystic fibrosis:

  • Bronchiectasis (Damaged airways)- Cystic fibrosis can cause bronchiectasis. This condtion damages the airways and makes it difficult to clear the mucus form the bronchial tubes and move air out of the lungs.
  • Chronic infections- Mucus n the sinuses and lungs are an ideal breeding spot for fungi and bacteria. People who have Cystic fibrosis are more prone in developing pneumonia, bronchitis and sinus infections.
  • Nasal polyps (growths inside the nose)- Since the lining of the nose tends to be swollen and inflamed, it can develop fleshy and soft growth (polyps).
  • Hemoptysis (coughing blood)- Cystic fibrosis can sometimes cause thinning in the airway walls. Teenagers and adults who have Cystic fibrosis can also cough up blood in severe cases.
  • Pneumothorax- In this condition the air starts to collect in the empty space which separates the chest walls from the lungs. Pneumothorax can also cause breathlessness and chest pain.
  • Nutritional deficiencies- Many times, thick mucus can create obstruction the tubes which carry enzymes aiding in digestion from the pancreas to the intestines. In such cases, the body fails to absorb fat-soluble vitamins, fats and proteins.
  • Distal intestinal obstruction syndrome (DIOS)- This condition is characterized by the complete or partial blockage where the large intestine meets the small intestine.
Can't be cured, but treatment helps Require medical diagnosis Lab test always required Chronic: can last for years or be lifelong Non communicable
Symptoms
Repeated lung infections. Inability to gain weight. Fatty stools.

Popular Health Tips

Cystic Fibrosis - 5 Strange Signs You Must Know About!

MBBS, MD - TB & Chest, Fellowship Training Intensive Care, Fellow College of Chest physicians, European Diploma in Respiratory Medicine, Interventional Pulmonology , Greece, European Diploma in Intensive Care Medicine, Fellow Indian college of critical care
Pulmonologist, Gurgaon
Cystic Fibrosis - 5 Strange Signs You Must Know About!

Do you know about a condition called cystic fibrosis that makes your baby’s skin taste very salty after birth? The condition changes over time, in which the body makes sweat and mucus, and also affects the digestive system and lung functioning. The condition generally occurs because of a flawed gene. This is a severe and life-threatening disease that affects different people in different ways.

Causes
The gene, called CTFR is present in all humans. It makes a protein that controls the amount of water and salt, which get moved in and out of your cells. In the case of cystic fibroids, the CTFR gene is broken. This happens when a person inherits two bad copies of this specific gene. One bad CFTR gene may cause your cells to make the wrong or imbalanced amount of water and salt. Because of this, your body becomes unable to get the supply of sufficient nutrients and oxygen that are lost through sweating.

Symptoms
There are several symptoms associated with cystic fibroids that include the following:

  1. It is likely for you to cough up thin mucus, along with shortness of breath, and wheezing.
  2. The development of polyps in your nose is indicated.
  3. Sinus infections, pneumonia, or bronchitis may occur.
  4. Your stool may be oily, bulky, and with a foul odor.
  5. Liver diseases and gallstones may develop later in life because of cystic fibroids.

Treatment
There is no certain treatment for cystic fibroids. However, there are various treatment procedures that are used for providing relief to the symptoms of the condition. This allows an affected patient to breathe easily, feel better, and experience lesser stomach infections. You can opt for airway clearance technique that helps you with your breathing. The procedure involves the clearance of mucus from your lungs. This procedure is carried out in several ways and special devices may be used during the proceedings.

  • Certain inhaled drugs like steroids, salt solutions, and antibiotics are used for thinning your mucus layers, and for clearing lung infections.
  • If your pancreas do not work properly, you may be prescribed enzyme pills for the digestion of fats and protein, and for the absorption of more nutrients from the food you consume.
  • You may also be prescribed vitamin A, D, and E supplements for getting these nutrients, which are not being absorbed by your intestine.
  • You must consult a doctor on experiencing any symptom of cystic fibrosis in your baby. This will allow the condition to be diagnosed at an early stage, thereby preventing further worsening. Consult an expert & get answers to your questions!
3135 people found this helpful

Influenza Vaccine - Why is it Important for Kids?

Senior Residency, MD - Paediatrics, MBBS
Pediatrician, Gurgaon
Influenza Vaccine - Why is it Important for Kids?

Influenza is more commonly known as the flu. It is an infection that affects the respiratory system and is caused by the influenza virus. This injection is recommended for kids who are under the age of 6 months. It ensures that the baby is safeguarded from the virus during an influenza outbreak. Since the nature of virus changes year on year, the immunity doesn’t last for more than 1 year. This vaccination is ideally taken during the month of October and November. The effect of the vaccination typically lasts for 6-8 months.

Ideally, kids who have never had a flu vaccination should take 2 vaccinations within 4 weeks. Kids who have received a shot of flu should undertake this vaccination once in a year. This arrangement is ideal up to 9 years of age. Flu shot is extremely important for a kid due to the following reasons:

  • It saves a kid from chronic lung and heart disorders such as asthma and cystic fibrosis
  • Kids suffering from immune deficiency, cancer, and HIV should take this vaccination to avoid further complication of the existing disease
  • Kids suffering from diabetes, kidney diseases, and metabolic disorders should go for this vaccination without a second thought
  • Kids suffering from a neurological disorder, haemoglobin deficiency, and anaemia should take this vaccination to refrain from the risk of aggravation of the present disease
  • Pregnant women should ideally take it for the safeguarding the fetus

Flu shot should not be taken be taken if:
1. A baby is under the age of 6 months.
2. The baby has thimerosal allergy.

Is flu shot safe?
The flu shot is considered to be very safe. It does not result in flu. Few side effects include:
a. Soreness of the place where the needle is injected. This doesn’t last for more than a couple of day.
b. Body ache and mild fever for the first couple of days after the vaccination is done.
c. There is little to no pain in the place where the injection is injected by the doctor.

What is nasal flu vaccine?
This is an influenza dose that is not injected into the body, but given in the form of nasal spray. Healthy kids above the age of 2 years are fit to get this injection. For those kids who have a history of chronic illness should check with their doctor to go ahead with nasal spray. Each dose is given in each nostril. Like the influenza vaccine, nasal flu vaccine should be undertaken once for those who have already taken this dose once. Kids who have not undergone this vaccination are eligible for 2 dosages each 4 weeks apart from each other. If you wish to discuss about any specific problem, you can consult a doctor.

2545 people found this helpful

Cystic Fibrosis- Causes and Symptoms!

DDF, FCCP, MD , MBBS
General Physician, Delhi
Cystic Fibrosis- Causes and Symptoms!

Cystic Fibrosis is a genetic disorder that is known to affect some of the vital organs of the body including the lungs, digestive system to name a few. For long it was believed that cystic fibrosis affects a person in their childhood. However, various research and studies suggest that adults are also susceptible to this inheritable disorder. In this article, we will discuss the cause and symptoms associated with cystic fibrosis.

Cause
The epithelial cells that line the stomach, nasal cavity and lungs, are responsible for the production of the digestive fluids, sweat, tears, mucus. The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene codes for a protein called the CFTR protein. The CFTR protein, a membrane protein plays a pivotal role in transporting the chloride ions of the epithelial cells inside and out of the cell. This regulation of the chloride ions goes a long way in ensuring that the mucus produced is free-flowing and thin.

In the case of Cystic Fibrosis, the CFTR gene that codes for the protein undergoes a mutation. With the CFTR protein unable to perform its function, sticky and thick mucus builds up and clogs some of the major systems of the body including the digestive system, reproductive, and respiratory system. There is also a higher salt content in the sweat of the affected person.

For a person to be affected by cystic fibrosis, he/she must inherit a copy of the mutated CFTR gene from both the parents ( Autosomal Recessive Disorder) at birth.

Symptoms
The symptoms associated with cystic fibrosis depends on the organs and systems affected.

  1. The thick mucus formed can clog the digestive tract resulting in incomplete absorption of the essential nutrients from the food. This may have an impact on the overall growth and development of the body.
    • - There may be stunted growth or no weight gain.
    • - The stool may appear greasy and foul smelling. Some may also suffer from constipation.
    • - Newborns and infants may suffer from an intestinal blockage.
  2. Cystic fibrosis, left unattended can lead to diabetes, intestinal blockage or obstruction.
    • - The mucus can also block the bile duct triggering a host of problems including liver disorders.
    • - At times, the obstruction or blockage can occur at the junction where the large and the small intestine meets (Distal intestinal obstruction syndrome).
  3. The thick mucus can also affect the lungs and the respiratory system by blocking the tubes that act as a passage carrying the air inside and out of the lungs. As a result,
    • - A person may suffer from lung infections frequently.
    • - There may be difficulty in breathing, stuffy and blocked nose, or wheezing.
    • - Some people may also suffer from a chronic cough with a thick sputum.

Left untreated the complications can worsen resulting in

Nasal polyps, Chronic infections, Hemoptysis (there is blood while coughing), and Pneumothorax (air fills up in the space bifurcates the chest wall from the lungs).

In severe cases, there may be a respiratory failure.

Cystic fibrosis can also trigger fertility problems (both in males and females).

1 person found this helpful

Treatment of Cystic fibrosis!

MD - Acupuncture, Diploma In Accupuncture, Advanced Diploma In Accupuncture
Acupuncturist, Delhi
Treatment of Cystic fibrosis!

Treatment of Cystic fibrosis
Homeopathic Treatment of Cystic fibrosis
Acupuncture & Acupressure Treatment of Cystic fibrosis
Psychotherapy Treatment of Cystic fibrosis
Conventional / Allopathic Treatment of Cystic fibrosis
Surgical Treatment of Cystic fibrosis
Dietary & Herbal Treatment of Cystic fibrosis
Other Treatment of Cystic fibrosis
What is Cystic fibrosis
Symptoms of Cystic fibrosis
Causes of Cystic fibrosis
Risk factors of Cystic fibrosis
Complications of Cystic fibrosis
Lab Investigations and Diagnosis of Cystic fibrosis
Precautions & Prevention of Cystic fibrosis

Treatment of Cystic fibrosis

Homeopathic Treatment of Cystic fibrosis

Homeopathy helps in getting healthy lung tissue and improvement in complaints like breathing difficulty, cough etc. Homeopathic treatment for cystic fibrosis helps the individual to feel better. It helps in reducing pain. Some of the homeopathic remedies for cystic fibrosis are:

Thuja
Calc
Silicea
Sang

Acupuncture & Acupressure Treatment of Cystic fibrosis

Acupuncture may help stimulate respiratory function, and improve immunity against infections in cystic fibrosis suffers. It involves inserting fine needles into specific points on the body.

Psychotherapy and Hypnotherapy Treatment of Cystic fibrosis

Some children with cystic fibrosis experience severe anxiety and depression. Different forms of psychotherapy and hypnotherapy are used to help children, including psychodynamic therapy, cognitive behaviour therapy and play therapy.

Conventional / Allopathic Treatment of Cystic fibrosis

Allopathic Treatment of Cystic fibrosis involves the following medications:

Antibiotics
Mucus-thinning drugs
Bronchodilators

Surgical Treatment of Cystic fibrosis

Surgical Treatment of Cystic fibrosis involves the following surgeries:

Lung transplant
Bowel surgery
Feeding tube

 Dietary & Herbal Treatment of Cystic fibrosis

Drink lots of fluids
Take high-calorie nutrition
Add seaweed and nutritional yeast to your diet
Avoid refined sugar
Avoid animal origin products
Other Treatment of Cystic fibrosis

Regular exercise helps loosen mucus in your airways and strengthens your heart and lungs.

What is Cystic fibrosis?

Cystic fibrosis is an inherited disorder that causes severe lung damage and nutritional deficiencies. It causes your mucus to be thick and sticky.

Symptoms of Cystic fibrosis

Persistent cough
Wheezing
Repeated lung infections
Repeated sinus infections
Belly pain from severe constipation
Foul-smelling, greasy stools
Delayed growth
Loss of appetite
Shortness of breath
Causes of Cystic fibrosis

Cystic fibrosis (CF) is caused by a defective gene which causes the body to produce abnormally thick and sticky fluid, called mucus. This collection of sticky mucus results in life-threatening lung infections and serious digestion problems. The disease may also affect the sweat glands and a man’s reproductive system.

Risk factors of Cystic fibrosis

Family history
Common in white people of northern European ancestry

Complications of Cystic fibrosis

Chronic infections
Collapsed lung
Bronchiectasis
Respiratory failure
Nasal polyps
Nutritional deficiencies
Osteoporosis
Electrolyte imbalances
Diabetes
Rectal prolapsed
Blocked bile duct

Diagnosis of Cystic fibrosis

Diagnosis of Cystic fibrosis involves the following tests:

Newborn screening test
Sweat test
Sputum tests
Genetic testing
Organ function tests
X-rays
CT scans and MRI
Lung function tests

Precautions & Prevention of Cystic fibrosis

There is no prevention for cystic fibrosis, but treatments can ease symptoms and reduce complications.

Cystic Fibrosis - Therapies That You Can Go For!

MBBS Bachelor of Medicine and Bachelor of Surgery, MD - Chest & TB
Pulmonologist, Faridabad
Cystic Fibrosis - Therapies That You Can Go For!

Cystic fibrosis is a genetic condition, which primarily affects the lungs and persistence of this condition might lead to severe breathing problems and loss of lung function. If you have inherited two copies of the defective gene from your parents, you are likely to suffer from this disease. Cystic Fibrosis causes a buildup of thick mucus in your lungs and affects other organs such as the kidneys, pancreas and the intestines in your body.

It isn't very uncommon as one out of fifty people in Asia is a carrier of this disease. The disease gets its name from the cysts formed in the pancreas of the sufferer. However, this disease can be detected by testing the quantity of salt present in your sweat. Prenatal testing for Fibrosis is another method to test if your newborn is likely to contract a lung infection.

Complications faced due to cystic fibrosis include:

  1. Serious sinus infections
  2. Serious damage in lungs due to inflammation and incessant infection
  3. Malnutrition
  4. Complication in breaking down protein
  5. Respiratory tract contamination

If you observe one or more of the following symptoms, you might be suffering from Cystic Fibrosis:

  1. Salty-tasting skin
  2. Bowel obstruction caused due to meconium ileus (obstruction of the bowels)
  3. Persistent coughing with phlegm discharge
  4. Shortness of breath while engaging in a physical task
  5. Stunted or measly growth despite healthy lifestyle habits
  6. Infertility in males

If you're suffering from cystic fibrosis, there isn't any particular treatment which is recommended due to the varying degrees of it found in people. However, consultation with a medical practitioner and an individualised treatment plan can help you minimise the risks and lead a better life.

Diagnosis:

Diagnosis of Cystic fibrosis can be made by measuring the quality of salt i.e. the amount of chloride in your sweat (sweat chloride test). Genetic testing for CFTR gene mutation detection can also be done at specialized centres. 

Some therapies you can opt for are:

  • Airway clearance: This therapy helps sift the thick layer of mucus around your organs. Some people have also chosen to use the inflatable vest which vibrates around your chest, thereby, thinning and loosening the layer of mucus.
  • Inhaled medicines: Another breakthrough in the field of respiratory medicine, this method requires the patient to sniff a liquid consisting of mist, which is inhaled with the aid of a nebuliser. This method is known to be beneficial for opening airways.
  • Pancreatic enzyme supplements: Along with multivitamins, these specially designed supplements are known to cater to your pancreas with the much-needed nutrients and they need to be consumed with every meal.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2605 people found this helpful

Popular Questions & Answers

Cect chest reveals small fibrosis lesions in both fields with subcentimeter sized lymphnoed in mediastinum, indicating sequelae of previous infective pathology.

MBBS, DM - Cardiology, md medicine
Cardiologist, Bhopal
If you are asymptomatic. No need of further evaluation. Just follow. But if you have any gastro intestinal symptoms consult gastro- enetrologist. Actually it's difficult to evaluate small size sub centermeter lymph node. Sometime they having no significant. So need to clinicaly correlation.
1 person found this helpful

I am 28 years male. My Fibro scan results are as follows: CAP (dB/m)-median 381 E (kPa)-Median 5 IQR .5 IQR/med 10% what do these result indicate?

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
FibroScan results range from 2.5 kPa to 75 kPa. Between 90–95% of healthy people without liver disease will have a liver scarring measurement <7.0 kPa (median is 5.3 kPa. YOur result is high and need to Assessed with general check up.

What is fibrosis apities both side and what is its treatment. Please give brief answer for the treatment.

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
Appetite stimulants, although efficacious in treating malnutrition in CF, should only be prescribed if decreased food intake secondary to inadequate appetite is the principal cause of the malnutrition and all other contributing factors have been assessed, ruled-out or treated. the use of several appetite stimulants used in CF and other diseases to improve appetite and maximize caloric intake