Cytodrox 500Mg Capsule is an oral medicene that is prescribed to patients suffering from chronic myelogenous leukemia, acute myelogenous leukemia, sickle-cell disease, ovarian cancer, cervical cancer, and polycythemia vera. Cytodrox 500Mg Capsule slows down the growth of cancer cells in the body and can reduce the need for blood tranfusion. It comes as a capsule that is usually taken once in a day. But talk to your doctor regarding the right dosage for you.
Common side effects of Cytodrox 500Mg Capsule drug are fever, loss of appetite, shortness of breath, headache, drowsiness, nausea, vomiting, bone marrow suppression, psychiatric problems. Contact your doctor if you notice any unusual symptoms such as dizziness, confusion, joint pain, seizures, tarry stools, sores in the mouth or unusual bleeding.
Do not use this medicine if; you are allergic to any of its ingredients; have a prescription for didanosine or stavudine; have severe bone marrow depressin; have anemia or count of white blood cells or platelets is low. Also, let your healthcare provider know before prescription if- you are pregnant or are planning to become pregnant, are breastfeeding, have a history of allergies to food or medicine, have anemia, kidney or liver problems or if you are a HIV positive patient.
Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Hematologist before using this medicine.
The Eosinophilic disorders are one of the major hematological diseases, which deal with the white blood cells in the human body. The Eosinophils or the white blood cells play an important role in the human body while responding to asthma, allergic reactions, and infections that are caused due to parasites. Eosinophils not only play an important role in protective immunity against parasites but also contribute a lot to inflammation which occurs during allergic disorders.
Different disorders of the Eosinophils
Low count of eosinophils
A low count of eosinophils in the blood usually occurs with the sepsis or the infections in the blood stream, cushing syndrome. They are usually treated with the corticosteroids. The treatment of the lower count of eosinophils is able to restore the normal count of the eosinophils.
High count of eosinophils
The condition of the high count of the eosinophils is known as eosinophilia or hypereosinophilia. Some of the most common causes which increase the count of the eosinophils are
Symptoms of eosinophilia
When the count of the eosinophils increases considerably, it can not only inflame the tissues but can also cause damage to the organs. The organs that are usually affected due to this are the heart, skin, lungs and the nervous system. People may suffer from skin rashes, shortness of breath or wheezing and fatigue. One can also suffer from throat as well as stomach pain if the stomach or the esophagus gets affected.
It is generally treated with antibiotics even if no infection is detected. Doctors usually treat such conditions with the oral corticosteroids.
Idiopathic Hypereosinophilic Syndrome
In this disorder, the eosinophil count increases to more than 1500 cells/microliter of blood. It is common in the ones who have crossed 50 and usually suffers from a condition of the heart known as Loffler endocarditis which leads to heart attacks.
Most of the people need to treat this with the drugs of prednisone, hydroxyurea and sometimes chemotherapy drugs. Eosinophilic disorders should always be treated according to the drugs prescribed by the doctors. If you wish to discuss any specific problem, you can consult a hematologist.
Have you heard of a health condition in which there are insufficient red blood cells in your body for carrying sufficient oxygen to all parts of the body? This condition is called sickle cell anemia and it is an inherited form of anemia. Usually, the red blood cells in your body are round and flexible and move through the blood vessels easily. In case of sickle cell anemia, the red blood cells become sticky and rigid. They are shaped like crescent moon or sickle. Because of the irregular shape, these can get stuck in the blood vessels, which slows down the blood flow.
The only potential cure of sickle cell anemia is a bone marrow transplant. Other treatment measures focus on easing the symptoms and preventing further complications. The various treatment modes are as follows:
It is recommended for you to consult a doctor on experiencing any symptom of sickle cell anemia. This is a dangerous health condition and requires proper diagnosis and treatment before it gets out of your hands.
Polycythemia is a rare condition where the count of red blood cells in the body increases. The normal count of red blood cells ranges from 4.9-5.2 million cells per cmm. People having polycythemia witness an increase in the count of hemoglobin, hematocrit or red blood cells as compared to the normal level.
Women with hemoglobin levels higher than 16.5g/dL and hematocrit value higher than 48, are believed to have polycythemia. In case of men, hemoglobin levels higher than 18.5g/dL and hematocrit value greater than 52 are suggestive of polycythemia.
A myeloproliferative disorder that involves an uncontrolled red blood cells formation in the bone marrow is called as polycythemia vera. It is a slow growing cancer involving the blood cells. The cells growing in an excess quantity cause a thickening of blood and cause a reduction in the flow rate of blood. Thickening or clot formation can lead to a stroke or a cardiac arrest. This condition can develop and progress without any symptoms and go undiagnosed for a long period of time. Lack of prompt diagnosis and treatment can cause the condition to become life-threatening. It may also progress to other forms of cancers like acute leukemia.
The two main types of polycythemia are primary and secondary. Polycythemia vera is symptomless usually. When symptoms appear, the commonly seen ones are as follows – constant headache of mild to moderate intensity, itchy rashes on skin, bruises with bleeding points, lethargy, blurring of vision, excess sweating, joint swelling and excessive pain, unexpected weight loss, neuropathy in limbs, low to moderate grade fever and even shortness of breath. There is no specific age group predilection for its incidence, it can occur at any age. However, the prevalence rate is common in adults over 60 years of age. The male to female ratio of occurrence is also even, with no gender predilection.
Polycythemia vera is not completely curable, with the treatment being focused on reduction of red blood cell count. Symptomatic treatment allows for reducing the complications related to the presenting signs and symptoms. Phlebotomy is done where the blood volume is decreased by drawing out of blood from the veins. Thrombolytic drugs like low dose aspirin is given to break clots. Anti-cancer drug Ruxolinitib helps in the destruction of cancer cells to some extent.
What are the possible causes of polycythemia?
Look out for the symptoms!
The usual symptoms of polycythemia include the following-
The symptoms may vary from mild to severe. If left untreated, polycythemia can lead to severe health complications like scarring of the bone marrow, acute leukemia or myelodysplastic syndrome. Recognizing the symptoms at an early stage can help prevent the complications.
This disorder can cause various complications, formation of blood clots in the body being the most common of them. Formation of such blood clots in organs like lungs can cause an embolism or in the blood vessels can cause an obstruction to the blood flow. Deep vein thrombosis is a common complication caused by the presence of a thrombus formation due to blood clot in the veins of lower limbs. Polycythemia also causes splenomegaly due to increased exertion on the spleen by the uncontrolled growth of red blood cells. Other complications include formation of ulcers in the intestines, joint inflammation and development of more severe blood disorders.
How is polycythemia treated?
Treatment of polycythemia depends on its cause and severity.
Phlebotomy is the procedure whereby the doctor uses a needle to remove a tiny amount of blood from the vein. This decreases the volume and count of red blood cells so that excess blood cells are not formed, and oxygen is carried to different organs in the body.
People who are at high-risk, or have reached an advanced stage, require more specialized treatment. Certain medications used in the treatment of polycythemia include-
Other treatment procedures for easing symptoms like persistent itching may include antihistamines, Selective Serotonin Reuptake Inhibitors (SSRIs) and phototherapy.