Betnovate 0.1% Cream

Manufacturer: Glaxosmithkline Pharmaceuticals Ltd
Medicine composition: Betamethasone
Prescription vs OTC: Prescription by Doctor required
Last Updated: March 21, 2022

Betnovate 0.1% Cream is primarily prescribed to treat various rheumatic disorders such as systemic lupus erythematous and rheumatoid arthritis. It is also used against various skin diseases including psoriasis and dermatitis, allergic conditions such as angioedema and asthma, certain blood disorders, certain eye and skin conditions. Betnovate 0.1% Cream belonging to the glucocorticoid class of medication, acts as a steroid.

Multiple sclerosis, crohn's disease and leukaemia can also be treated with Betnovate 0.1% Cream. It can be administered into the body orally, in the form of an injection or applied as a cream. Being a corticosteroid, it works by decreasing inflammation and modifying the body's immune response to various conditions.

You are advised to not take this medication if you have allergy, systemic fungal infection or an active untreated infection. Betnovate 0.1% Cream can interact with a few other medicines so inform your doctor if you take amlodipine, mifepristone, warfarin, ethinyl, estradiol, insulin, ciprofloxacin, BCG vaccine.

Also inform your doctor if you suffer from tuberculosis, electrolytic imbalance, gastrointestinal perforations, infections, myocardial infarction, ocular herpes infection, scleroderma or threadworm infection. This medicine is not recommended to use during pregnancy or breastfeeding unless absolutely required, in which case breastfeeding should be discontinued.

Serious side effects may include an increased risk of infection, severe allergic reactions, muscle weakness, and psychosis. Using Betnovate 0.1% Cream for a long time can cause adrenal insufficiency. Discontinuing the medication suddenly after a long-term use may be dangerous. The cream commonly results in skin irritation and increased hair growth.

Take Betnovate 0.1% Cream as instructed by the doctor. Your dosage duration, timings, forms and other attributes can vary depending on the medical condition and hence following instructions are necessary to ensure this medicine is safe and effective to use.

Take oral medication with or after meals. Limit intake of caffeine or stimulants. Prescriber may recommend increased dietary vitamins, minerals, or iron. Diabetics should monitor glucose levels closely (antidiabetic medication may need to be adjusted). Inform prescriber if you are experiencing greater than normal levels of stress (medication may need adjustment).

Some forms of this medication may cause GI upset (oral medication may be taken with meals to reduce GI upset; small frequent meals and frequent mouth care may reduce GI upset). You may be more susceptible to infection (avoid crowds and persons with contagious or infective conditions).

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

The primary use of this medication is as follows:

  • Allergy And Inflammation

  • Joint Inflammation

  • Eye Inflammation

  • Skin Disorders

  • Allergy

  • Systemic Fungal Infection

  • Active Untreated Infection

Here are some of the possible side effects of this drug:

  • Blurred Vision

  • Increased Appetite

  • Indigestion

  • Anxiety And Nervousness

  • Skin Itch

  • Drying And Cracking Of Skin

  • Acne

  • Change In Skin Color

  • Persistent Infections

  • Irregular Menstrual Periods

  • Depression

  • Growth Retardation In Children

  • Hoarseness Of Voice

  • How long is the duration of effect?

    The time duration for which this medicine remains effective is subject to vary depending on the form and route of administration.
  • What is the onset of action?

    The effect of this medicine can be observed within a few minutes after oral administration as it is rapidly absorbed from the gastrointestinal tract. It is subject to vary depending on the route of administration.
  • Are there any pregnancy warnings?

    Use of this medicine during pregnancy is not recommended unless absolutely necessary and the benefits outweigh the risks. Consult your doctor before using this medicine.
  • Is it habit forming?

    No habit forming tendencies were reported.
  • Are there any breast-feeding warnings?

    Use of this medicine while breastfeeding is not recommended. However, if it absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.
  • Is It safe with alcohol?

    Consult your doctor before consuming alcohol.
  • Is it safe to drive while on this medicine?

    It is safe to drive while you are taking this drug unless you experience side effects of blurred vision.
  • Does this affect kidney function?

    It must be used cautiously if the patient has a history of kidney disorders.
  • Does this affect liver function?

    It does not affect the liver adversely.

Below is the list of medicines, which have the same composition, strength and form as Betnovate 0.1% Cream , and hence can be used as its substitute.

  • Missed Dose instructions

    Contact your doctor for instructions if you missed a scheduled dose of this medicine. A self-attempt to make up for the lost dose may result in adverse effects.
  • Overdose instructions

    Contact your doctor if an overdose with this medicine for is suspected especially when the prescribed dose is very high. Symptoms may include thinning of the skin, easy bruising and bleeding, body fat deposits etc.
  • India

  • United States

  • Japan

Betnovate 0.1% Cream is a potent glucocorticoid with minimal mineralocorticoid action. It decreases inflammation by inhibiting the migration of leukocytes and reduces the permeability of capillaries and inhibiting prostaglandins and other inflammatory mediators.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Interaction with Lab Test

    Information not available.
  • Interaction with Medicine


    Report the use of either of the medicine to the doctor. Taking these medicines together may reduce the efficacy of Amlodipine. You may need a dose adjustment and more frequent monitoring of blood pressure levels while using them together.


    These medicines should not be used together. Combining them would significantly reduce the efficacy of betamethasone. Your doctor may determine the best course of treatment in such cases.


    Report the use of either of the medicine to the doctor. You may need a dose adjustment of warfarin based on the result of clotting time test performed. Any incidence of unusual bleeding and bruising, chest pain, loss of vision, swelling of arms and feet should be reported to the doctor immediately.

    Ethinyl Estradiol

    Ethinyl estradiol can potentially reduce the efficacy of betamethasone. You may need a dose adjustment and special test to safely use these medicines together. Do no stop the use of any medicine without consulting your doctor.


    Report the use of either of the medicine to the doctor. You may need a dose adjustment of the diabetic medicine and more frequent monitoring of blood glucose levels while using them together.


    Report the use of either of the medicine to the doctor. The risks of adverse effects are significantly high especially in the elderly. Your doctor may prescribe a suitable alternative. Any pain or swelling of the tendons in the ankle, shoulder, biceps etc should be reported immediately.

    BCG vaccine

    This medicine should not be used when you have taken a vaccine containing a live and attenuated strain of the bacteria or virus. Report any recent vaccine taken to the doctor so that suitable alternatives could be prescribed.
  • Interaction with Disease


    This medicine should be used with caution in patients who have recently recovered from tuberculosis. The risks of a relapse are significantly high and hence close monitoring of signs and symptoms is necessary.

    Electrolyte Imbalance

    This medicine is known to cause imbalances in the levels of minerals like calcium, potassium, and sodium in the body. Hence it should be administered with caution in patients with a pre-existing electrolyte imbalance disorder.

    Gastrointestinal Perforations

    This medicine is known to cause perforations and bleeding in the gut especially when high doses are consumed. Hence this medicine should be administered with caution in patients having a pre-existing perforation disorder of the stomach or intestine.


    This medicine can suppress the immune system especially if the dose is high. This may increase the chances of contracting an infection or reduce the capacity to fight an infection. Hence, this medicine or corticosteroids, in general, should not be used in patients with active infections.

    Myocardial Infarction

    This medicine should be used with extreme caution in patients who have recovered or are recovering from a recent heart attack.

    Ocular Herpes Infection

    This medicine should be used with caution if the patient is suffering from an eye infection caused by herpes simplex virus.


    This medicine should be used with caution in patients suffering from this disease where the skin and connective tissue beneath becomes hard and stiff.

    Threadworm Infection

    This medicine should be used with caution in patients suffering from an infection caused by threadworm (Strongyloides).
  • Interaction with Food

    Information not available.

Ques: What is Betnovate 0.1% Cream?

Ans: This drug is a steroid that inhibits the formation of chemicals in the body that may lead to inflammation (redness and swelling) and allergies.

Ques: What are the uses of Betnovate 0.1% Cream?

Ans: Betnovate 0.1% Cream is helpful in treating allergic conditions.

Ques: What are the side effects of Betnovate 0.1% Cream?

Ans: Thinning of skin, Increased risk of infection, Weight gain, Mood changes and Behavioural changes are some of the known side effects of this medication.

Ques: Is Betnovate 0.1% Cream a steroid?

Ans: Yes, the drug comes under the category of corticosteroids and can help with many conditions including allergic reaction.

Ques: Is Betnovate 0.1% Cream safe to use?

Ans: This medication is considered safe to use if used in dose and duration as prescribed by the healthcare professional. However, it is not safe to use Betnovate 0.1% Cream if you have a known history of allergy to it.

Ques: Does Betnovate 0.1% Cream cause hair loss?

Ans: Betnovate 0.1% Cream does not cause hair loss. Moreover, it can lead to an increase in hair growth on the body when this drug is used for longer duration. Consult your doctor if you encounter this side effect.

Ques: Can I take Betnovate 0.1% Cream with ibuprofen?

Ans: It is suggested to first inform your doctor before taking any other medications in combination with Betnovate 0.1% Cream to avoid the risk of any adverse interactions. Ibuprofen is a non steroid and may cause certain problems when taken with a steroidal drug like Betnovate 0.1% Cream.

Ques: Does Betnovate 0.1% Cream cause weight gain?

Ans: Yes, this medication may lead to problems of weight gain in some individuals. This is more prominent if the drug is consumed for a long term. Please consult your healthcare expert if you are facing this symptom.

Ques: Is Betnovate 0.1% Cream a hydrocortisone?

Ans: No, this medication is not a type of hydrocortisone. Hydrocortisone is another type of drug that also belongs to the category of corticosteroids.

Ques: Is Betnovate 0.1% Cream over the counter?

Ans: This medicine is not an over the counter (OTC) drug. It can be used only when it is prescribed by a doctor.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Betnovate 0.1% Cream
What are the uses of Betnovate 0.1% Cream
What are the contraindications of Betnovate 0.1% Cream ?
What are the side effects of Betnovate 0.1% Cream ?
Key highlights of Betnovate 0.1% Cream
What are the substitutes for Betnovate 0.1% Cream ?
What are the dosage instructions?
Where is the Betnovate 0.1% Cream approved?
How does this medication work?
What are the interactions of Betnovate 0.1% Cream ?
FAQs about Betnovate 0.1% Cream