Endometrial receptivity array test (ERA) is recommended to ascertain the receptivity of the endometrium for embryo transfer. The endometrium is the inner lining of the uterus. Once the eggs are released from the ovaries, the endometrium prepares itself for receiving the fertilized egg.
Women patients who are unable to conceive naturally may have problems with the embryo reception/implantation process. Assessing the receptivity of the endometrium or the optimum time for the embryo to be introduced to the uterus becomes pertinent for the success of assisted reproductive procedures. In a natural cycle, the uterus prepares automatically for the implantation and reaches the optimal thickness as the embryo is released from the ovaries. In an artificially induced cycle, the embryo has to be introduced externally, there are no means to ascertain the state of the endometrium at the time of embryo transfer. The embryo was transferred in accordance with conventional wisdom about the length of cycles and scans. However, this approach does not take into account that individual cycles that may differ.
Gynechologits use endometrial receptivity array treatment as a reliable measure to test the readiness of the uterus. The test involves a biopsy of the lining to analyze the tissues. Certain genes are activated in a receptive endometrium. The test determines the presence of these genes and their level of activation. It is generally carried out a month prior to the IVF cycle, and the results are used to determine the time for embryo transfer. This technique is particularly useful for patients who have had repeated failures during the implantation process.