Irrfan Khan's saddening revelation about his health and diagnosis of Neuroendocrine tumour (NET) has undoubtedly created a rage amongst his fans, which is now being followed by good wishes for speedy recovery from his supporters all across social media.  

The actor shared in an emotional Twitter post that he s been diagnosed with NET, a rare tumour that develops from cells of the neuroendocrine system and grows predominantly in the digestive or respiratory tract - lungs, appendix, small intestine, rectum, and pancreas - it can occur in any part of the body.

Here is more on Irrfan s disease:

What is NET?

A neuroendocrine tumor is characterized by a rapid and abnormal growth that happens in the nerve cells which produce hormones. Hormones control how different organs in the body work.

It is a condition wherein, endocrine cells, the hormone-producing cells of the body, develop a tumor in any part of the body - while it can can grow in lungs or the thymus, or more rarely, in the ovaries, kidneys, or testicles - the most common is lung, intestines, and pancreas.

What causes NET?

A neuroendocrine tumour is quite a rare disease, occurs in less than one per million cases. The exact cause is not known.

The Symptoms-

It can cause a myriad of symptoms, depending on where in the body the NET is.

If it is in your digestive system, it can cause pain or discomfort in the abdomen area that comes and goes. You may feel sick, nauseated, vomited, or there may be a change in how often you pass stools.
If the NET is in the lung, it can cause shortness of breath, chest infections, or you can even have a cough up blood.
Weight loss and loss of appetite may also be some common signs of a neuroendocrine tumour.
Some NETs may overproduce a hormone-like substance called serotonin. This causes a group of symptoms called carcinoid syndrome. Symptoms include wheezing (like asthma), flushing of the skin and diarrhoea.
Who can be affected with NET?

These tumours, depending on the type, are more common in certain age or sex. And few have very strong family history too.
People who have a rare condition called multiple endocrine neoplasia 1 have an increased risk of developing a NET.
Did You Know?

Apple founder  Steve Jobs  died from the same disease in 2011. The tumour affected his pancreas.

Know The Different Types of NET:

Based on the organ that is affected, NET can vary a lot. When the chromaffin cells that produce adrenaline are affected, it is called Pheochromocytoma, and it is related to the stress levels of the body.

When a cell is formed abnormally under the skin and the hair follicles, it is called Merkel cell cancer. This is also called neuroendocrine carcinoma of the skin and the condition can occur anywhere in the body. The commonly occurring places include lungs, gastrointestinal tract, and brain.

The status of the tumour, cancerous (malignant) or noncancerous (benign), decides the survival rate. Often slow-growing and noncancerous, they can invade surrounding parts of the body and at times, turn cancerous and spread across the body. However, you can still choose to live a good quality life with strict modifications in diet and lifestyle. The changes are made after taking into consideration the symptoms of the tumor. The organ where the tumor is formed also matters.

How Is It Treated?

Treatment depends on the location of the tumour, its type, how severe it is and whether it has spread to other parts of the body. Usually, the first treatment choice is surgery to remove the tumour. And, if the NET cannot be removed, your will prescribed with a treatment that will not only relieve the symptoms but will also improve the quality of your life.

How can a NET be prevented?

The first thing you need to do for the prevention of NET is to curb stress. Stress affects the entire body severely.

Lifestyle modifications:

A healthy lifestyle is what you need to stick to if you want to manage its symptoms during the treatment cycle. Your doctor will prescribe you to do exercises at least 4 days a week for a minimum of 30 minutes. You can also try a walk instead of strenuous exercises.

People with carcinoid syndrome may be advised to avoid food or activities that may trigger flushing, such as eating spicy food or drinking alcohol.

Indulge yourself in therapies that help in gaining more positive energy. If you are already affected by NET, eliminate all the sources of stress and get a good night's sleep every day. Join the support groups that make you grow strong and happy. After all, the mind is devised to do miracles when it is full of life and positive thoughts.

Is Irrfan Khan's tumour curable?

Dr Saumitra Rawat, HOD, Surgical Gastroenterology & Liver Transplant, Sri Ganga Ram Hospital, said, "NeuroEndocrine Tumour is an abnormal growth of Neuroendo cells which are present in bodies. When there is an abnormal growth, then it forms a tumor - Normally seen in intestine, pancreas, lung, thyroid and other parts of the body".

On commenting on Khan's case, he said, "It depends on the location of tumour, its size, and what is its mitotic index".

"Depending on where the tumour is localized, you can take it out surgically and the chances of cure are very high", Dr Rawat explained.

Actor Irrfan, who has been diagnosed with the disease is one of the most versatile actors in India, has also made a name for himself in the west, where he has been an important part of critically-acclaimed films such as  The Namesake ,  Jurassic World , and  Life of Pi . At home, the actor has delivered remarkable performances in films such as  Haasil ,  Paan Singh Tomar ,  Maqbool ,  Lunch Box ,  Piku , and the most recent  Hindi Medium .

Irrfan Khan is not just a disarmingly natural actor, but also an endearing human being -- honest and humble to the core. It s time to stand together and pray for him a speedy recovery!

Irrfan Khan - Battle Against Neuroendocrine Tumour!

Are you aware of the link between air pollution and cancer? Air pollution refers to the mixture of several harmful substances, which lead to various serious health hazards on exposure. The primary sources of air pollution are man-made, including fumes from automobiles and the smoke from burning fuels. Desert dust, radon gas, and several other natural sources of air pollution are equally dangerous. Air pollution is classified into outdoor and indoor air pollution. It is highly associated with increased risks of developing cancer. Smoking is considered to be one of the major agents, which pollute the air and increase the chances of cancer to a large extent.

Outdoor air pollution

Outdoor air pollution is strongly linked with cancer development.
As every person is exposed to some form of air pollution, it has a more harmful effect on the whole population across the globe as a general threat.
A certain part of outdoor air pollution referred to as PM 2.5, or solid dust particles, are highly responsible for the development of cancer.
The chances of cancer increase with the increase in PM 2.5 levels in the air.
Indoor air pollution

There are several sources of indoor air pollution that are closely associated with an increased risk of cancer.
The sources include fuels used for heating homes and for cooking, radon, and tobacco smoke.
Second hand smoke is another harmful indoor air pollutant that causes cancer.
Second hand smoke

Secondhand smoke increases the risk of cancer development, along with the risk of developing other diseases such as stroke and lung disease.
A lot of people all over the world get exposed to second hand smoke.
A lot of deaths occur due to cancer because of second hand smoke exposure which is common every year, all over the globe.
Radon

Radon is a natural radioactive gas, which is associated with increased risks of developing lung cancer.
It is found at low levels outdoors. It may also build in high concentrations indoors.
Although radon exposure does not pose a huge threat for cancer, a lot of radon-associated cancers develop due to exposure to radon, along with tobacco smoke.
Benzene

This is a flammable liquid having no color and with a sweet odor.
It is closely associated with the development of leukemia and cancers affecting other cells of the body.
Cigarette smoking and tobacco smoke are major cancer causing elements that are found in the air commonly. Both of these are quite harmful. It is recommended that you not only quit smoking, but also keep away from passive smoking.

Pollution and Cancer - How They Are Related?

Science has advanced a lot through the ages. Doctors have also succeeded in curing many diseases in this time. But even with one of the most advanced technologies, they still haven t found a fool proof way to cure cancer. Even out of the many types of cancer, blood cancer is the worst among them. You surely wouldn t want to get into such a situation. Would you? The best way out of blood cancer is never to get one. To prevent it you can take care of a few things:

Maintaining proper body weight: Although you can t do much to prevent cancer, you must ensure that you maintain a healthy body weight. This implied that your BMI should be normal (healthy weight) so that you have a good chance of fighting it. It has been said by many leading institutions worldwide as the best way to prevent cancer. One can maintain proper body weight by making sure they exercise every day for at least 30 minutes and also maintain a well-balanced diet. This would help you maintain a healthy body weight.
Reduction in the consumption of calorie dense food: Not only because calorie dense foods like cold drinks increase your weight, the sugar mixes with your blood and thus is difficult to transport through the body. Thus they add a lot of impurities to the body and must be avoided for the best interests in your effort to fight cancer. The worst fact about calorie dense foods is that you can easily consume 1000   2000 calories long before you can satisfy your hunger. Thus, it also defeats your first preventive measure to avoid cancer.
Staying away from harmful chemicals like pesticides: You might not know it and be happily spraying pest control sprays everywhere without a proper mask thinking you will make the pests go away. What you don t know is that those pesticides are harmful for your blood and one should avoid them. To increase the probability of winning against blood cancer, it s vital to keep this in mind.
Consulting a doctor from time to time: One should always go and visit a medical practitioner from time to time so that they can maintain proper health. Furthermore, if you see symptoms like fever, frequent infections, night sweating, swollen liver with abdomen pain, enlarged lymph nodes (they are usually painless), then be sure to go to a medical practitioner. Always remember that prevention is better than cure. Thus one should try to prevent blood cancer not cure it.

Blood Cancer - How To Prevent It? 

Cancer today is not as rare as it once was. Today, cancer affects the young and old alike. One of the reasons for this is the pollution in particular air and water pollution that we are exposed to on daily basis.
The air we breathe in today is a mixture of smoke, particulate matter and noxious gases that causes great harm to our bodies. Amongst these, particulate matter that is smaller than 2.5 millionths of a metre is the worst.

These particle matters are emitted into the air from car exhausts, industrial exhausts, coal fires, wood stoves etc. While the body s natural defences help keep larger particle matter out of the system by sneezing or coughing it out, smaller particle matter enters the body easily. These then get trapped in the lungs and enter the bloodstream. Particle matter has in particular been linked to increasing number of lung cancer cases. Apart from lung cancer, coal tar particle matter has been linked to bladder cancer, soot to oesophageal cancer and benzene and other pesticides to leukaemia.

Radon is another source of air pollution that is emitted from the ground. In some cases, radon can also be emitted through the water. As this gas decays, it releases tiny particles that when inhaled bombard the lung cells with radiation that can cause radiation. Smoking can worsen this effect and increase a person s risk of suffering from lung cancer. Both first-hand and second-hand smoking have also been linked to breast cancer. Apart from trying to reduce emissions to lower air pollution, it is also important to clean filets of air conditions, etc. regularly to lower indoor air pollution. Preventing the smoking of tobacco in public spaces can also help improve air quality.

All pollutants emitted by us eventually find their way into the water we drink. Even if you are not drinking contaminated water, merely, showering or swimming in contaminated water can make your body more vulnerable to the carcinogens in it. Common water pollutants include arsenic, hazardous waste, animal waste, radon, chemicals and asbestos. Drinking water with concentrated amounts of arsenic has been linked to cancer of the lungs, liver, kidney and bladder while the chlorine used to treat drinking water increases the risk of bladder and rectal cancer.

To reduce the risks of cancer caused by polluted water, it is essential to reduce disinfectant by products by keeping water treatment facilities updated and promote green chemistry and alternative assessments to reduce pollution as a whole.

Pollution - How It Has Increased the Risk Of Cancer?

Developing cancer is either totally your bad luck where you haven t been doing anything wrong in your diet and lifestyle still develop it or it is out of bad lifestyle, eating habits and negative attitude towards life. But death due to cancer is totally due to carelessness in which a person didn t pay attention to initial symptoms and left cancer for thriving in the body. The truth has been said that cancer isn t a killer but delayed diagnosis and wrong or improper treatment is. Awareness, early diagnosis and treatment is the key to survival. Cancer does not always mean death if some earlier signs of cancer are noted and action is taken timely.

In normal conditions our body functions normally, i.e. we eat, pass urine and stool, breath, and drink water. Any alteration from this is abnormal and must be noticed like difficulty in swallowing, difficulty in urinating and defecating, passing blood in urine or stool, long continued severe pain in any part of the body.

The appearance of new moles on the body which keep on growing with an irregular border, painful and bleed.

Hoarseness of voice

Long persisting cough and blood in saliva. Cough lasting more than a month.

Loose stools or any change in bowel habits without any dietary changes lasting more than a few weeks needs to look into.

Presence of blood in stool without any obvious reason like ulcers or hemorrhoids.

Unexplained low blood count, i.e. anemia. Anemia needs to be evaluated unless there is any obvious source of blood loss.

Not all breast lumps are cancerous but all of them should be investigated. Also if there is any bloody discharge or discharge only from one nipple that should also not be ignored at all. Self-examination of the breast daily once a week is necessary and it is easy too. Check for any nodule or discharge from the breast.

Any lump in the testicles should be evaluated thoroughly. Men should also do a self-examination of the testicles, once in a month.

Urinary symptoms like less urine, pain while passing urine, blood or burning in urine, especially in men shouldn t be ignored. It can be a sign of bladder or pelvic cancer

Hoarseness without any respiratory infection or persistent for more than 3-4 weeks.

Normally lymph nodes swell due to any surrounding infection and then shrink eventually when the infection goes away. If it remains for a longer time and without any infection in the body, should be investigated.

A mole that is multicoloured with irregular borders, bleeding can be cancerous. Especially which is growing rapidly and is painful shouldn t be avoided at all.

Long continued heartburn and difficulty in swallowing even after using over the counter antacids. This can be a sign of esophageal cancer.

Bloody discharge or bleeding from the vagina which is unusual or after menopause can be due to cancer of the uterus or cervix.

Unobvious or unexplained weight loss, fever or night sweats can be an early sign of different types of cancer.

Continuous itching in the genital or anal area, non-healing sores and pain in back, head, bloating and indigestion which is there for a long time without any cause, should be inspected.

Cancer can be horrifying and debilitating but if diagnosed early by giving attention to the symptoms mentioned above and treated properly can fight off. Cancer is no more incurable if treated early. In cases where this disease is out of carelessness if some points are kept in mind and followed, prove to be preventive. If not preventive then definitely reduce the risk of developing it at least.

Do not overuse the birth control pills. Using them randomly can increase the chances of cancer.

Excessive consumption of alcohol shouldn t be done as it irritates the gastric mucosa and increases the incidences of malignancy. However, an occasional glass is fine and does no harm.

Avoid using pesticides around you or having things on which they are sprayed as many of them are definitely carcinogen.

Say no to smoking as tobacco in any form is an invitation to death. Smoking for a long time like 10-30 years can make you pay a heavy price for that.

Long continued anxiety and stress create havoc in the hormonal system of the body which ultimately results in diseases. Try to keep yourself more optimistic and relax in daily life.

Prefer organic vegetables and fruits as other ones have pesticides used while growing them which are definitely a source of getting carcinogens in the body.

Limit intake of processed and packaged food as they increase the risk or certain types of cancer. 

Stay active and try to maintain healthy weight.

Cancer can be the biggest slayer of the health but one can fight it and keep it at bay if mentioned tips are read and implement. Early diagnosis can prevent many lives. So spread awareness and let more people know about it. 

Cancer - A Misfortune Or Carelessness!

According to a major study that provides a connection between height and cancer, it is stated that taller people are more prone to developing cancer. Research has found that the risk of developing any kind of cancer in women rises by 18% for an increase of every 10 cm in height. In men, the risk rises by 11%, even though height is not as major a factor as are obesity, smoking and a bad, unhealthy diet.

Several reasons have been put forward for the above statement. One of the reasons is that the number of body cells in taller people is more than people with average height. This leads to an increase in the number of cells which could potentially turn malignant.

While individually analysing the impact of height on different cancer forms, it was found that the highest increase in risk was in skin cancer (30% for every 10 cm increase in height), while a 20% increase was noted in taller women developing breast cancer.

Development of cancer in regions including the colon and rectum is known as colorectal cancer. Long legs have been surprisingly associated with this form of cancer. In comparison with shorter people, it was reported that taller people had a higher risk percentage of developing colorectal cancer. Two hypotheses regarding the formation of colorectal cancer have been developed. One hypothesis is that taller people have longer colons, which in turn result in more surface area where colon cancer can develop. The other hypothesis is that taller people experience increased levels of growth hormones. These particularly affect the length of their legs. The growth hormone called 'insulin-like growth factor 1' is increased during puberty and is considered to be a risk factor for colorectal cancers occurring at later stages.

Being Taller Increases Your Risk of Cancer!

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