Chromosomal abnormality happens when a cell has too many or too few chromosomes. The most common form of chromosomal anomaly is Down s syndrome. If a parent has a chromosomal anomaly, she/he will pass it on to the child. PGD or Pre-implantation Genetic Testing aims to select only the embryos with normal chromosomal count and only these embryos are implanted to achieve a healthy pregnancy and bring down the number of children affected with a chromosomal anomaly.

The risk of Aneuploid pregnancy:

The older a woman is when she tries to conceive (aged 35 or more), the higher the risk of Aneuploid pregnancy (carrying a baby with genetic or chromosomal abnormality). Most of these pregnancies end in miscarriages and the few that come to term produce babies with chromosomal abnormalities.

Causes of Chromosomal Abnormality:

Usually, chromosomal abnormalities occur due to an error in the cell division. Meiosis refers to the cell division, which the sperm and the egg undergo during the development procedure. Normally, meiosis breaks the chromosomal material into two equal halves, so that each of the parents contributes 23 chromosomes to the pregnancy. However, when the number of chromosomes in the cell goes up or down than the normal, it results in genetic/chromosomal anomalies.

PGD Procedure for a Chromosomal Anomaly:

If a couple elects to go for Pre-implantation Genetic Diagnosis, they have to undergo ICSI Cycle. ICSI cycle initiates a fertilization cycle to produce embryos. When the embryos reach upto day 5 and blastocyst are formed, they are biopsied and further sent to genetic lab for detecting the chromosomal abnormalities. The embryos are incubated for the entire duration of the genetic screening. Only the embryos that the genetic test clears are implanted. PGD never reveals the gender of the embryo.

PGD can help detect the single genetic disorders that may lead to the following ailments:

  Cystic fibrosis
  Muscular dystrophy
  Tay-Sachs
  Sickle cell anaemia
  Thalassemia
  Turner syndrome

PGD is a revolutionary science that can help root out incurable disorders linked to genetics. It ensures that pregnancy is sustained until term and a healthy baby is born.

Suffering From Genetic & Chromosomal Anomalies - Know About PGD!

Obesity is the new-age lifestyle disease with multiple ramifications. While its effects on the physical aspects are very evident, the damage it does to the brain are more severe, though not obvious. Read on to know some harmful effects of obesity on the emotional well-being.

Leads to binge eating: There is a certain pleasure in eating sugary and fatty food, and this is lost with depression. Therefore, to get that emotional satisfaction, people tend to eat more chocolates, cookies, milkshakes, and other weight-accumulating food items, which further add to obesity. Greater the weight gained by a person, lesser the response or happiness from such food products.
Increases impulsivity: The area of the brain known as orbitofrontal cortex, which is in charge of controlling impulsivity, shrinks in obese people. This results in people eating more impulsively.
Affects immunity: Obesity is a major cause of inflammation, leading to damage in certain parts of the brain. This impairs the immune system, making the affected person more prone to infections and tissue damage. This leads to increased chances of diabetes, heart disease, stroke, sleeping disorders, eating disorders, etc. The chemical known as C-reactive protein increases as seen on MRIs in obese people, and which is usually seen in patients with chronically increased inflammation.
Effects on memory: As the BMI increases, there is a decrease in scores of memory tests. This effect is more obvious in women after menopause. With increased fat accumulation, more hormones are released, which affects the memory. Increased inflammation also affects cognition and memory.
Increased risk of dementia: With more belly fat accumulating, there is extra stress on the body to burn the visceral fat. This reduces brain size and causes certain hormones to release, which further affects the body s ability to remember things. It has been proven that people with smaller brain size are at greater risk for developing dementia.
Weight loss stress adding to more stress: When obesity sets in and the BMI goes up, there is an added pressure to lose weight, which further ups the stress levels. During these dieting days, the brain is constantly alert and finds ways to eat more. This also leads to excess eating. Moreover, there are indications that there could be genetic changes during this phase, which may leave a permanent mark in the person s composition.
Depression: When a person is not happy with their reflection in the mirror, the chances of feeling good and happy are very less. In this age, where aesthetics plays a major morale booster, an obese image staring back does not help at all.
So, if you have a risk of obesity, watch out. It is not just how you look, but how you feel is also altered.

Obesity - How It Affects The Human Brain?

Silk pillowcase slows down skin aging

Using silk pillowcase is known to slow down skin aging by giving you a wrinkle-free skin. This is due to many good qualities of silk fibers.

Silk is a natural fiber obtained from animals and contains amino acids which are compatible and friendly to the human skin. It also contains temperature regulators which adjust your skin to the changing temperatures. Hypoallergenic silk fibers resist many skin allergens like fungus, spores etc making it ideal for sensitive skin.

The tightly woven fiber which remains most in contact with your face retains moisture to your skin and keeps your skin well hydrated. Unlike dry and flaky skin, moistened skin cells are most likely to show fewer wrinkles and hence slow down skin aging process.

Did You Know a Silk Pillowcase Can Slow Down Your Skin's Aging?

The pitta dosha can be balanced by consuming fresh and whole foods, both raw and cooked. These foods are energising, cooling, dry, and have high carbohydrate content. They can effectively deal with pitta by fighting inflammation, absorb excess oil and liquid, and reduce internal heat. Pitta is basically liquid that is light, hot, sharp, oily and tends to spread fast. In light of this, the diet should comprise food that is dense, cool, dry and mild. Due to pitta s substantive nature, a proper diet can help to strike the right balance. 

Here is an overview of achieving a pitta balance to get rid of digestive problems:

Cold food: Surprising as it may sound, food with a low temperature helps in balancing the pitta dosha compared to its hot counterparts. Raw foods tend to have a decreased temperature compared to the cooked ones. Having a good mix of raw fruits and vegetable is, therefore, part of a good a diet. Stay away from all types of caffeine and alcohol while following a pitta diet.
Dense, nourishing and grounding food: Although heavy food might sound ideal to tackle light weight pitta, Ayurveda is the view that heavy food does more harm than good. Food that fits the bill includes root vegetables, cooking oils, grains, milk, and seeds. Since these foods tend to be sweet, it is necessary to ensure that a portion size is kept in mind and one must not overindulge in order to refrain from putting on weight. Food that should be slashed from the regular diet includes processed fast foods, pastries, heavy snacks that comprise chemicals and preservatives, and sweet beverages.
Dry food instead of liquid: Between a semi-liquid and solid meal, the latter should be chosen since it helps in fighting pitta better. Some of the ideal food that fits the bill include pasta, potatoes, beans, oats, millet, corn and other leafy green vegetables. While cooking it is advised that a good quality ghee or oil is used. Some food stuff that needs to be totally slashed from the existing diet includes nuts, cheese, cream, olives eggs and nuts. Mild food:
In terms of food flavours, it makes sense to choose flavours that are gentler and milder in taste such as the ones found in apples, soft cheese, cucumbers and lime juice over sharp flavours such as vinegar, pineapple, old cheese, and pickles. Simultaneously stimulants such as hard alcohol, nicotine, drugs etc. should be completely eschewed in order to avoid indigestion. This is especially true during night-time when the level of indigestion is more due to reduced mobility of the body. 

Pitta - How It Affects Digestion?

If you are suffering from gastritis, it is important for you to know about the most ideal tips and treatment methods related to the condition. Gastritis is an inflammation, irritation, or erosion of the stomach lining called gastric mucosa. The most common symptoms of the condition include nausea, vomiting and illness in the upper abdomen, right after having a meal. Heartburn, abdominal pain, loss of appetite, indigestion and bloating are other symptoms of gastritis.

Here are 10 tips for treating gastritis using simple home remedies:

Carom seeds: Carom seeds are natural antacids and are effective for curing gastritis. They give relief to the mucous membrane of the stomach from acidity and hyper acidity. Nausea, indigestion and bloating are also treated.
Ginger: Ginger treats gastritis effectively because of its antibacterial and anti-inflammatory properties. It reduces inflammation, treats infections and eases gas, stomach pain and nausea.
Yoghurt: Yoghurt is essential when you are suffering from gastritis. Yogurt containing active live culture is more beneficial in the case of this disease. It contains probiotics, which protect the stomach lining from the bacteria that causes gastritis. Your immune system also gets a boost.
Chamomile: Chamomile tea works wonders in treating gastritis. It contains several essential oils, which are helpful for your digestive system. It also soothes the intestinal walls, giving relief from pain. Stomach inflammation also goes down.
Peppermint: This herb is also efficient for gastritis treatment because of its anti-inflammatory, antispasmodic and antibacterial properties. Its soothing properties reduce inflammation and also help with heartburn, indigestion and nausea.
Strawberries: Strawberries are also beneficial in healing gastritis because of their antioxidant properties and phenolic compounds. They help in preventing the start of stomach lining inflammation.
Holy basil: Holy basil helps in healing acute gastritis because of its anti-inflammatory and antibacterial properties. These help in reducing inflammation and infection. Stomach pain, vomiting, and nausea are also reduced.
Fennel seeds: Fennel seeds help in soothing your digestive system and relaxing your gastrointestinal tract muscles. This is an important part of gastritis treatment. These seeds contain antispasmodic, anti-inflammatory, and stomachic properties and are beneficial in relieving symptoms such as indigestion, intestinal gas, heartburn, and vomiting.
Licorice: This Ayurvedic remedy for gastritis contains anti-inflammatory and soothing properties which help in reducing inflammation. Symptoms such as heartburn and indigestion are also treated. The stomach s inner lining is protected from infection, thereby reducing the risk of ulcers.
Raw potato juice: Raw potato juice is considered to be an important remedy for gastritis because of its antacid and healing properties. The alkaline properties of potato help in reducing cramps, bloating, and other common symptoms of the condition.

Gastritis - 10 Home Remedies For It!

Vitiligo is a disease that causes the loss of skin shading and colour in patches. The degree and rate of colour loss from vitiligo cannot be determined. It can influence any part of the skin on your body. It might also influence one s hair, inside of the mouth and even the eyes. 


Ordinarily, the shade of one s hair, skin and eyes is measured by melanin. Vitiligo happens when the cells that create melanin quit working or die. Vitiligo influences individuals of all skin types; however, it might be more common in individuals with a darker skin. The condition is not contagious or life threatening.


Numerous medicines may be used to restore the skin shading or level out the skin tone. A few medicines might have some serious side effects on some people. So your specialist may propose that you first try to improve your skin by applying self-tanning products or make-up. Here are some of the top ways to treat vitiligo:


Medicines 
Creams that control aggravation: A topical corticosteroid may cause the skin to return to its natural shade (repigment), especially if you begin utilising it right at the start of the disease. 
A type of vitamin D: Topical calcipotriene (Dovonex) is a cream that can be used with corticosteroids. Possible reactions include dry skin, rash and itching. 
Medicines that influence the immune system: Treatments containing tacrolimus or pimecrolimus (calcineurin inhibitors) might be compelling for individuals with little ranges of depigmentation, particularly on the face and neck.
Therapies
Light therapy: This uses a narrow band of UVB light. You may get treatment in a specialist s office up to three times each week. 
Laser treatment: This technique brings the shading back to the patches of light skin by treating them with an excimer laser, which utilises a particular wavelength of UVB light. 
Depigmentation: A solution with monobenzone is connected to the unaffected zones of the skin. This progressively lightens the skin so that it blends with the affected areas.
Surgery
Skin grafting: In this system, your specialist removes little segments of your ordinary, pigmented skin and joins them to regions that have lost colour. 
Rankle grafting: In this system, your specialist makes blisters on your pigmented skin with suction. He or she then removes the highest points of the blisters and transplants them to a range of stained skin. 
Micropigmentation: In this method, your specialist utilises an extraordinary surgical instrument to embed colour into your skin. 
Other treatments
Shield your skin from the sun and UV light. In case that you have vitiligo, especially in case you have light skin, use a wide range of waterproof sunscreen with an SPF of not less than 30. 
Abstain from tattoos that are not associated with treating your vitiligo. 
Make-up concealers may enhance the appearance of the skin and help you feel better about yourself, particularly if your vitiligo patches are on uncovered skin.


4 Top Ways You Get Vitiligo Treated

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