Glomerulonephritis is a disease that is caused due to inflammation of the small filters that are present within the kidneys or glomeruli. Glomeruli eliminate the excess waste, electrolytes and fluids from the blood, discharged through urine. A glomerular disease can be either acute or chronic. If the condition arises without a combination of any other disease, it is termed as primary glomerulonephritis. Secondary glomerulonephritis is characterized by diabetes or lupus (an auto-immune disorder) being at the root of the disease. Prolonged or severe inflammation can take a toll on the kidneys.


Causes-


Nephrotic syndrome can be primary, being a disease specific to the kidneys, or it can be secondary, being a renal manifestation of a systemic general illness. In all cases, injury to glomeruli is an essential feature. Kidney diseases that affect tubules and interstitium, such as interstitial nephritis, will not cause nephrotic syndrome.


Primary causes of nephrotic syndrome include the following, in approximate order of frequency:
Minimal -change nephropathy
Focal glomerulosclerosis
Membranous nephropathy
Hereditary nephropathies


Secondary causes include the following, again in order of approximate frequency:
Diabetes mellitus
Lupus erythematosus
Viral infections (e.g., hepatitis B, hepatitis C, human immunodeficiency virus [HIV] )
Amyloidosis and paraproteinemias
Preeclampsia
Allo-antibodies from enzyme replacement therapy


Nephrotic- range proteinuria may occur in other kidney diseases, such as IgA nephropathy. In that common glomerular disease, one third of patients may have nephrotic- range proteinuria.


Nephrotic syndrome may occur in persons with sickle cell disease and evolve to renal failure. From a therapeutic perspective, nephrotic syndrome may be classified as steroid sensitive, steroid resistant, steroid dependent, or frequently relapsing.


Treatment-
Whether one is suffering from acute or chronic nephrotic glomerular , with symptoms moderate or severe, the treatment lies in treating high blood pressure and other underlying conditions of the disease.
Water pills help control sweating, thus increasing the fluid flushed from the kidneys.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
For kidney failure, dialysis can come to the aid in eliminating excess fluids and regulating hypertension.


Nephrotic Syndrome: Causes and Treatment

Kidney stones can range from being the size of a grain to a pebble. These stones can be described as crystallized mineral deposits in the kidneys. Some kidney stones can be passed out of the body along with urine while others may require surgery. Symptoms of having a kidney stone vary from mild to severe. In the case of very small kidney stones, the patient may not experience any symptoms at all. The 5 most common kidney stone symptoms usually experienced are:

Pain: Pain in the lower abdomen and back is one of the most common symptoms of having a kidney stone. This may be felt just below the ribs, on the centre and sides of the abdomen, in the lower back and in the groin. The intensity of pain is not directly related to the size of the kidney stone. This pain can come and go and will vary in terms of intensity. In certain cases, the pain can be severe enough to warrant a trip to the hospital. This pain is usually a sign that the stone is moving.
Frequent Urination: People suffering from kidney stones may find themselves needing to go to the bathroom more often than normal. In some cases, patients may also wake up in the middle of the night with the urge to urinate. However, only a small amount of urine may be passed at a time. This is a sign that the kidney stone has moved into the lower urinary tract. Small stones may later be passed out of the body along with urine.
Bloody Urine: Urine should ideally be pale yellow. Patients suffering from kidney stones may notice that their urine is darker than normal and cloudy. There may also be blood in the urine. This is known as hematuria. The colour of blood in such cases can range from pink to brown. Cloudy urine is also considered a sign of a urinary infection. This is a sign that the urine also contains pus cells or pyuria.
Nausea: Vomiting and nausea are common symptoms of kidney stones. This is caused by the nerve connections shared by the kidneys and the gastrointestinal tract. The presence of kidney stones in the kidneys or urinary system can trigger an upset stomach. Some people also feel nauseous because of the pain caused by kidney stones.
Foul Smelling Urine: Under normal conditions, urine should not have a very strong smell. Urine that smells bad is a symptom of a urinary infection. Bacteria in the kidneys or urinary tract can be the cause of this smell. It may also be caused by the high concentration of urine. 

5 Symptoms Of Kidney Stones!

Most people believe kidneys to be organs solely responsible for the filtration of blood and production of urine. But the truth is that the kidneys perform a host of vital functions in the body which include regulation of blood pressure, blood volume, and blood Ph. Around half of the individuals affected by lupus suffer from kidney problems, and the most affected part is the glomerulus whose function is filtering substances from the blood.

Effects of lupus nephritis on the kidneys
Lupus itself doesn t lead to kidney infection or inflammation. But lupus nephritis, which is the Systemic lupus erythematosus (SLE) that affects the kidneys and the medications used for treating the condition tend to suppress the immune system. It makes the person affected with lupus vulnerable to the infections of various types. It is one of the most severe conditions of that could be encountered by a person wherein the immune system starts attacking various parts of the body as they would tackle a disease.

Lupus nephritis makes the kidney unable to remove the waste materials effectively from the blood. This leads to loss of control over the amounts of fluids regulating in the body. As a result, an abnormal amount of waste can build up in the blood resulting in edema or swelling.

When left untreated, these conditions can cause scarring along with permanent damage to the kidneys and end-stage renal disease. When a person has end stage renal disease, he or she needs regular filtering of the waste products of the body with the help of a machine. In severe cases, a kidney transplant may be required to ensure that at least one kidney is working properly.

Individuals who are susceptible to developing lupus nephritis:
A person with lupus may see the symptoms of lupus nephritis within 5 years and the people aged between 20 and 40 years are most vulnerable to it. In some common instances, it is seen that lupus nephritis is leading to unexplained weight gain along with swelling and puffiness in different parts of the body such as ankles, hands, eyelids, legs, and feet. During the first stages, these symptoms are often ignored which causes worsening of the condition. The urine may also become frothy or foamy with a reddish tinge in it. It is estimated that about 40 percent of children having lupus would develop kidney complications. Lupus nephritis may also cause increased urination, blood in the urine and elevated blood pressure.

If you have lupus, it is imperative to consult with a nephrologist. Testing a sample of the urine can help in showing the problems in the functioning of the kidneys. Your doctor will advise you about the diagnostic tests that can help in determining whether the disease has progressed to severe levels and start with the treatment process accordingly.

How Does Lupus Nephritis Affect Your Kidneys?

The urinary tract starts from the kidneys to the urethra where urine is passed out. Given the rich concentration of minerals and toxic wastes, it is highly prone to multiple infections. UTI, as urinary tract infections are often referred to, is one of the most common infections. In women, especially, every 1 in 2 women is affected by an UTI. Whichever part of the tract is affected, the symptoms and treatment are mostly the same. Read on to know some of the most common symptoms and treatment options for these.

Symptoms

A burning sensation with urination
Pain with urination
Burning sensation or pain in the urethra or vagina
Frequent urge to urinate, though not much urine is passed out
Sense of incomplete emptying of the bladder
Pain in the lower back on the sides of the spine
Change in the urine characteristics color, smell, or appearance
Fever or chills, maybe associated with shivering, nausea and vomiting
Causes

Most urinary tract infections are bacterial in nature, and these could find their way into the body through multiple ways.

The most common is through the urethra, which could happen due to unclean toilet habits.
Women especially are advised to wipe the urethra after each toilet visit. The bacteria from the feces can also enter the urethra due to close proximity
Use of unclean public toilets is another reason for UTIs
Tests

Though most often UTI does not require specific testing, the following are useful in confirming the diagnosis.

Culture and sensitivity: The urine is sent for a culture to identify the exact organism that has caused the infection. It also helps identify the right antibiotic which will help bring the infection under control.
Treatment:

UTIs are very common infections and though there is nothing to worry, it should be cleared completely.

Antibiotic course to get rid of the infection. Though you begin to feel better, the complete course should be completed to clear the infection.
Following culture testing to ensure the infection is cleared
Improve water intake to get rid of the toxins
Fever and pain to be controlled with medications
Healthy hygiene habits to ensure clearing of infection
Prevention:

Recurrent UTIs is a common problem, and the following can help prevent.

Ensure complete emptying of the bladder
Drink adequate water
Safe toilet habits, including before and after sex
Comfortable and clean underwear to prevent infection

Urinary Tract Infection - 8 Signs You Are Suffering From It!

Bladder stones, not to be confused with kidney stones, are formed when substances such as calcium oxalate found in urine coalesce into solid lumps and form deposits in the bladder. Though usually small enough to be excreted during urination, sometimes they get trapped in the neck of the bladder. In such cases, as the residues continue to grow larger, they cause extreme pain, infections, and may need surgical attention.

What causes bladder stones?
The most common causes of bladder stones are-

A diet which is high in oxalic acid can cause bladder stones.
Dehydration and a reduced intake of water cause bladder stones.
A protracted use of a urinary catheter, infections of the urinary tract, or an injury that might have impaired bladder function can cause stones to form.
Most often, stones originate somewhere else in the urinary tract and move downwards obstructing the neck of the bladder. There are significant hereditary factors at play here.
Symptoms-

Blood in the urine usually apparent only in the last few drops.
Interruption of the stream of urine and an inability to do so except in certain positions.
Dark-coloured urine.
Diagnosis-

1.Physical Exam
The physician will physically examine to evaluate if the bladder or the rectum are enlarged.

2.Urinalysis
A sample of your urine will be tested for the presence of bacteria, blood and crystallized minerals.

3.CT scan
A CT scan to build a detailed image of the internal organs.

Treatment-

If the size of the bladder stones is small then a simple increase in water and fluid intake should be enough to excrete them out naturally.
If they are too large to flush out from the system naturally, they will either be broken down to smaller sizes using laser ray or similar other energies, or surgically removed.
In order to prevent bladder stones from recurring, here are 5 foolproof methods-

1.Increase the daily fluid intake
A sure-fire way to prevent bladder stones is to increase the amount of water you drink every day. The idea is to reduce the concentration of your urine. A minimum of 2-3 litres of water per day is absolutely necessary.

2.Urinate more often.
If you drink more water throughout the day, you are going to have to urinate more frequently anyway. Do not put it off because you are worried that you will be mocked for having an old lady s bladder.

3.Laxatives.
If you feel like you are constipated, use a laxative. There is no shame in wanting to regulate your bowel movements.

4.Regular Tests.
Get a sample of your urine tested regularly to ensure that your kidneys and bladder are functioning properly and there are no irregularities.

5.Eat fruits.
Get the essential sugar component of your diet from fresh fruits. Say no to saturated sugar and fizzy drinks. Opt for fruits with high water content like melons to add more fluids in your diet.

5 Full-Proof Methods To Prevent Bladder Stones!

The kidneys are the main excretory organs and remove all toxins and wastes from the body in a liquid medium, the urine. The urine is normally straw coloured as there are filters which do not allow blood to enter the kidneys. However, due to various reasons, when there is a disease in the urinary tract, red blood cells can escape into the urine. The urine then assumes a pinkish tinge; the exact colour would depend on the amount of blood leaked. While the thought of pinkish urine is scary, it becomes a bigger concern when seen in children. Read on to know a little more about the types, causes, and ways to manage this condition. 

Types: 

Microscopic: When there is blood visible only through a microscope. This is quite common in children, and unless there is no accompanying kidney disease, it does not pose a problem when found occasionally. 
Gross: It is when the color of the urine changes to a pinkish tinge. This is of concern and requires immediate attention. 
Causes: 

There are various reasons and some of them are listed below 

Inherited causes: Conditions like sickle cell disease, polycystic kidney disease, Kidney stones and inherited nephritis. 
Structural causes: Cysts in the kidneys can cause hematuria 
Trauma: An injury (to the abdominal area) during sports should be ruled out, which could have damaged the problem 
Infections: Infections along the entire urinary tract right from glomerulonephritis to kidneys to bladder can cause blood in the urine 5.   Imbalances in minerals: High levels of serum calcium, which puts them at a higher risk of developing kidney stones later. Dietary calcium should be reduced. These children also could have a history of stones in the family. 
Idiopathic: When the cause of the hematuria is not known, it is termed idiopathic. 
Associated issues/Diagnosis: 

Hematuria is an indication or a symptom of an underlying medical condition (be it infection or trauma) and the underlying cause always needs complete evaluation. Accompanying symptoms can help narrow down the diagnosis. If any inherited cause is suspected, presence of hematuria should always be assessed in parents and grandparents. 

Check for history of trauma 
Known prior kidney disease 
Symptoms of infection 

Family medical history 
Urine tests to analyse its composition 
Urine culture, MRI, CT scanning, or biopsy may be required in more serious cases. 
When to worry? 

Associated proteinuria 
Microscopic hematuria which is persistent 
Kids with high blood pressure 
Kids with other existing kidney diseases 
Management: 

In most cases, no specific treatment for hematuria is required as the condition subsides after the underlying problem is addressed. For instance, once the infection clears, the hematuria also clears. Follow-up urine tests may be required to confirm that it is cleared. Blood in urine must always be evaluated by pediatric nephrologist as its causes range from very mild disease to rapidly evolving kidney failure, which may occur over days to weeks.

Blood In Urine In Kids - Know The Reasons Behind It!

Don't wait any longer, manage your Home Hemodialysis Nurse online with a Lybrate doctor today

Consult for Home Hemodialysis Nurse - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES