Schnitzler s syndrome is a very rare condition described by a reddish rash that looks like hives (urticaria) and lifted levels of a particular protein in the blood (monoclonal IgM gammopathy). Symptoms connected with the Schnitzler disorder may include increased levels of fever, joint inflammation, joint pain (arthralgia), bone agony, and different discoveries, for example, swollen lymph nodes (lymphadenopathy). It also causes weight reduction, discomfort, exhaustion, and broadened spleen and liver. This condition should be treated in terms of taking care of the symptoms so that they do not become debilitating.

Some of the other symptoms include the following:

Urticaria (hives) depicts red raised patches of the skin. These are once in a while irritated. They may last for about 12 hours to 3 days. This may become severely painful if not treated in time.
80% of such patients suffer from painful or swollen. A few patients experience bone pain as well.
High fever might be there accompanied by chills and night sweating. This can give rise to further uneasiness and is usually caused when the immune system is attacked by the ailment.
One of the main symptoms of the Schnitzler disorder is monoclonal gammopathy. This mostly means a raised level of immunoglobulin M (IgM)
Reasons behind it

The main cause behind the Schnitzler syndrome is unknown. Specialists believe that particular parts of the immune system may not work appropriately in the end because of the Schnitzler syndrome. Individuals with the Schnitzler disorder additionally have monoclonal IgM gammopathy, in which abnormal production of immunoglobins result in elevated levels of immunoglobulin M (IgM) in the body. Immunoglobulins are proteins delivered by the white blood cells. A few analysts believe that IgM antibodies accumulate in the skin (epidermis), setting off a reaction that causes the rash. At the time of diagnosis, IgM levels may just be somewhat raised and may stay stable for quite a long time.

Diagnosis

The diagnosis of the Schnitzler disorder is based upon an intensive clinical assessment, patient history, rejection of different other disorders and proof of fever, joint pain or aggravation, bone pain, discernible lymph nodes, amplification of the liver or spleen, lifted quantities of white platelets (leukocytosis), raised red platelet (erythrocyte) or anomalies, which can uncover expanded bone thickness (osteosclerosis).

Treatment: 
Anakinra is a successful treatment for Schnitzler syndrome. It is also very commonly used to treat rheumatoid joint inflammation. The following medicines and therapies have been proven to be successful for treating the Schnitzler disorder over a period of time. These are as follows:

Antihistamines
Nonsteroidal calming specialists
Systemic steroids (prednisone)
Hydroxychloroquine
Colchicine
Dapsone
Pamidronate
Thalidomide
Pefloxacin
Phototherapy
Immunosuppressive specialists (ciclosporin, methotrexate, cycloposphamide)
Biologic specialists (tocilizumab, rituximab)
The Schnitzler disorder is a long-term infection, so stopping a promising treatment can tend to cause a relapse and may cause the disease to reappear. Also, the medicines mentioned above should not be taken without consulting a doctor as they can have sever side effects, if not administered under the guidance of a physician.

Schnitzler Syndrome - Things You Must Know About It!

Hives are a common allergic reaction that appears in the form of swollen, red bumps or patches on the skin. These usually appear suddenly and cause itchiness. In some cases, it may also sting or burn. Hives can affect any part of the body including the face, ears, tongue, lips and throat. Hives are usually small in size but may grow as large as the size of a dinner plate. In some cases, hives may also join together to form plaques.

Hives are caused as a result of the production of histamines in the body that make plasma leak out of blood vessels in the skin. These histamines are released as a result of an allergic reaction, exposure to chemicals, insect bites, sunlight or adverse reactions to certain medicines. There are four main types of hives:

Acute Urticaria: These hives usually last for less than 6 weeks. They are triggered by insect bites, allergic reactions to food, latex, medicines or by exposure to infections. The most common food items that trigger this type of hives are chocolates, nuts, fish, tomatoes, eggs, soy, wheat and milk. Aspirin and other medicines like ibuprofen, ACE inhibitors and codeine can also trigger these hives.

Chronic Urticaria: Hives that last for longer than 6 weeks fall into the category of chronic urticaria. IT is harder to find what triggers a case of chronic urticaria than it is for acute urticaria. Along with the triggers mentioned above, hormonal disorders, tumours, chronic infections and immune system disorders can also trigger these hives.

Physical Urticaria: Hives caused as a result of physically stimulating skin are called physical urticaria. This includes sudden exposure to heat or cold, sunlight, vibrations, pressure, exercise etc. These hives usually resolve themselves within an hour and only affect the part of the skin that has been stimulated.

Dermatographism: Hives caused by scratching or firmly stroking the skin fall under this fourth category.

Hives can also be genetic in nature. Some people suffer from hereditary angioedema which is a painful swelling under the skin.

Hives caused by an allergic reaction can recur and hence if you suffer from hives you should try and identify the allergen. This can be done by taking an allergen test in a hospital or by changing aspects of your diet and studying the results. Hives are usually treated with antihistamines but in some cases, steroids may also be needed. However, it is usually nothing to worry about.

What Are Hives? What Causes Hives?

Hives or urticaria is an outbreak of reddish swollen bumps around the skin surface, formed mainly due to the body s response to particular allergens. Generally, the infectious bumps are of varied shapes and sizes and last for about 5-6 weeks. Although not a serious medical condition, hives can cause tremendous discomfort to the concerned person and affect his/her daily activities. Hives can be cured with a prescribed dosage of antihistamines or oral corticosteroids.

Causes of hives

Although the exact reason behind their formation is still unknown, researchers suggest that this disorder occurs as a response to involuntary histamine release by the skin blood vessels (that in turn, causes a leakage of blood plasma). Some other factors that can be responsible are:

Hives can occur due to insect or parasite bites.
Hives can also result as a side effect of painkillers such as codeine and other anti- inflammatory drugs such as ibuprofen or ACE inhibitors.
Excessive exposure to sunlight or high levels of stress (leading to high cortisol levels in the body) can also result in hives.
Intense scratching around the same spot can also result to hive formation.
Excessive alcohol intake can render you even more vulnerable to this disease.
Excessive intake of foods such as eggs, fish, nuts, chocolate and berries might also cause hives. Additionally, excessive consumption of certain food preservatives can also trigger the release of histamine.
Suffering from serious underlying medical conditions such as cancer, hepatitis or thyroid disorders can make you prone to chronic cases of hives (which might last for more than 6 weeks).
Symptoms of hives 
The symptoms of hives include, but are not limited to:

Appearances of several reddish welts around the face or arms which might cause a severe itchy sensation.
Painful and abnormal swelling around the mouth
You might also feel tightness in your chest along with recurring bouts of dizziness.
If not treated promptly after diagnosis, hives might result in life-threatening allergic reactions, such as Anaphylaxis (narrowing down of the bronchial tubes, thus causing significant breathing trouble) and auto-immune disorders such as rheumatoid arthritis.

7 Things that Can Cause Hives

If stressed, consuming certain food and medications can trigger skin rashes. This kind of rash is called hives. It is also known as urticaria. Anyone can be affected by hives, at least 20% of people are affected by hives at some time or the other in their lives. The itching could be severe or mild. It starts as a patch of scaly white skin that develops into red welts over time. To make sure the itching does not worsen, scratching, emotional stress, alcoholic drinks and exercise should be avoided.

Symptoms
1. Itchy bumps that are raised and are either red or flesh coloured
2. If the hive is pressed in the middle, the skin whitens this symptom is called blanching.
3. The hive formation can appear anywhere, disappear and then reappear somewhere else.

Common Triggers
1. Certain food like shellfish, eggs, peanuts and other nuts
2. Certain medicines like antibiotics, ibuprofen and aspirin
3. Insect bites or stings
4. Physical causes like pressure, sun exposure, cold, exercise and heat
5. Latex
6. Blood transfusions
7. Bacterial infections
8. Pet allergens
9. Viral infections like the common cold, hepatitis and infectious mononucleosis
10. Certain plants like poison ivy and poison oak
11. Pollen

Treatment
There is no distinct cure for hives. But you can control its symptoms in the following ways:
1. Antihistamines help in blocking histamines, which cause the allergy symptoms. Non sedating or low sedating Antihistamines will be mostly recommended by your doctor.
2. If episodes of hives are several, it may require limited treatment with prednisone. Prednisone will be able to lessen the symptoms.
3. If the symptoms get severe enough so much so that it swells up your tongue and you have problem breathing, then the doctor might prescribe an epinephrine. However, these symptoms can mean another thing, an anaphylaxis shock. Epinephrine is the only treatment for an anaphylaxis shock.

Prevention
If what caused hives to break out is figured out, then measures should be taken to avoid or eliminate the triggers.
1. Avoid eating food items that triggered the symptoms in the first place
2. If harsh soaps, frequent bathing cause hives, they should be avoided
3. Tight clothing should be avoided
4. If cold triggers hives, then wear warm clothing, wrap a scarf and do not swim in cold water.
5. Avoid sun exposure and wear sunblock
6. If a specific medication is causing the hives, inform your doctor.

All About Hives

Urticaria, commonly known as hives, usually occurs due to an allergic reaction. Sheetapitta is a similar condition in Ayurveda, as the symptoms are similar. Sheetapitta is comprised of two words-  sheeta  (cold) and  pitta  (warm). The condition occurs due to dominance of cold (existing in kapha and vata dosha) over pitta dosha.

Causes of Sheetapitta/urticaria-
Ayurveda believes, sheetapitta is caused due to the following reasons-

Excess intake of pungent (katu) and salty (lavana) food, mustard
Over consumption of sour gruels
Sleeping during the day
Contact with cold substances
Exposure to cold wind
Improper emesis (vomiting)
Insect bite (keeta damsha)
Coming in contact with poisonous bugs and insects (krimi samsarga)
Effect of seasonal changes on the body
Due to the factors mentioned above, especially because of exposure to cold wind, kapha and vata doshas become aggravated, and inevitably combine with pitta dosha. These spread all over the body and produce rashes on the surface of your skin.

Symptoms-
A person having sheetapitta/urticaria will encounter these symptoms-

Itching/pricking sensation
Nausea/vomiting
Fatigue
Tastelessness (aruchi)
Thirst (pipasa)
Lethargy
Reddish discoloration of the eyes (rakta lochanata)
Fever
Ayurvedic approach to cure Sheetapitta-

Ayurveda focuses on eradicating the doshas and purifying of the body toxins with Ayurvedic medicines & Panchkarma procedures. This is the essential part of Ayurvedic approach to cure urticaria. Abhyanga (massage), svedana (fomentation), vaman (induced vomiting) and virechen (induced lose motion) are very effective in treating Urticaria.

Ayurvedic treatment for Urticaria (Sheetapitta)-
Ayurvedic treatment for urticaria involves body purification therapy like Samshodhana, and oral medications. Some popular, effective techniques used in the treatment are-

Applying mustard oil all over the body
Applying mustard oil mixed with Saindhava lavana and Yavakshara
Use of a herbal powder named Eladi choornam that contains natural ingredients like elaichi
Applying medicated paste prepared from Haridra and Doorva, Kushta and Ghee over the rashes
Apart from these, herbs such as Guduchi, Yashtimadhu, Amalaki are recommended in the treatment of sheetapitta
Although urticaria is not a fatal condition, it can seriously affect one s quality of life. Many people suffer from urticaria for several months or years. Continual intake of conventional medicines reduces body s immunity. Moreover, the incidence of recurrence of this condition is often found. Thus, Ayurveda has an upper hand in treating hives, as it offers a comprehensive and permanent solution for this problem.

Sheetapitta - Causes, Symptoms & Ayurvedic View On It!

 Hives  or  urticaria  can be defined as an outbreak of reddish swollen bumps on the skin surface. This happens because of the body s response to involuntary histamine release by the skin s blood vessels (which in turn, cause a leakage of blood plasma). The infection generally lasts for about 5-6 weeks, varying significantly in sizes and shapes. Although it is not a serious medical condition, hives can posit considerable discomfort to the affected person (coupled with severe itching and a constant burning sensation near the spot).

Although the exact reason behind the development of this condition is still unknown, researchers suggest that there are some factors that initiate the disorder.

Hives can occur as a result of insect or parasite bites.
In some cases, this disorder might occur as a side effect of painkillers or anti-inflammatory drugs.
Excessive intake of alcohol or foods rich in proteins such as eggs, fish, nuts, chocolate, berries etc. might also cause hives.
Excessive exposure to the harmful UV rays of the sun or high levels of stress can also result in hives.
Also, suffering from serious underlying medical conditions such as cancer, hepatitis or thyroid disorders might drastically aggravate chances of chronic hives as well.
Symptoms

Development of numerous reddish welts around the face or the arms along with a severe itchy sensation, recurrent feeling of tightness around the chest and constant dizziness.
Oral inflammation
If not treated immediately after diagnosis, this disorder might cause life- threatening allergic reactions such as Anaphylaxis (a condition which narrows down the bronchial tubes and causes significant breathing troubles) and auto-immune disorders such as rheumatoid arthritis.

The homeopathic preparations useful for treating hives have been mentioned below:

Apis mellifica: This medication works best for a case of hives that has resulted from insect or parasite bites. Other symptoms that are taken care of by this medication include severe itching and a stinging sensation that worsens at night or with exposure to cold, coupled with mild fever.
Arsenicum album: This homeopathic preparation is effective to cure hives that include symptoms of a burning sensation, abnormal swelling, and constant restlessness.
Ichthyolum and Astacus: This preparation is effective to cure chronic hives caused due to serious medical conditions such as uric acid, tuberculosis, or excessive alcohol consumption. People suffering from this particular type exhibit symptoms such as a large appetite, irritability, and a constant itchiness.

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